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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

DRG2 Gene

protein-coding   GIFtS: 61
GCID: GC17P017992

Developmentally Regulated GTP Binding Protein 2

(Previous name: developmentally regulated GTP-binding protein 2)
Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Developmentally Regulated GTP Binding Protein 21 2
Developmentally Regulated GTP-Binding Protein 21
Developmentally-Regulated GTP-Binding Protein 22
DRG-23

External Ids:    HGNC: 30301   Entrez Gene: 18192   Ensembl: ENSG000001085917   OMIM: 6029865   UniProtKB: P550393   

Export aliases for DRG2 gene to outside databases

Previous GC identifers: GC17P018236 GC17P019363 GC17P017934 GC17P018191 GC17P017932 GC17P017744


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for DRG2 Gene:
This gene encodes a GTP-binding protein known to function in the regulation of cell growth and differentiation.
Read-through transcripts containing this gene and a downstream gene have been identified, but they are not
thought to encode a fusion protein. This gene is located within the Smith-Magenis syndrome region on chromosome
17. (provided by RefSeq, Jan 2012)

GeneCards Summary for DRG2 Gene: 
DRG2 (developmentally regulated GTP binding protein 2) is a protein-coding gene. Diseases associated with DRG2 include smith magenis syndrome, and tuberculosis. GO annotations related to this gene include GTP binding.

UniProtKB/Swiss-Prot: DRG2_HUMAN, P55039
Function: May play a role in cell proliferation, differentiation and death

Gene Wiki entry for DRG2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000017.10  NT_010718.16  NC_018928.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the DRG2 gene promoter:
         HNF-3beta   POU2F1   POU2F1b   POU2F1a   HNF-1   POU2F1c   NF-Y   CBF(2)   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidDRG2 promoter sequence
   Search SABiosciences Chromatin IP Primers for DRG2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DRG2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17p11.2   Ensembl cytogenetic band:  17p11.2   HGNC cytogenetic band: 17p13-p12

DRG2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DRG2 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17P017992:  view genomic region     (about GC identifiers)

Start:
17,991,200 bp from pter      End:
18,011,292 bp from pter
Size:
20,093 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: DRG2_HUMAN, P55039 (See protein sequence)
Recommended Name: Developmentally-regulated GTP-binding protein 2  
Size: 364 amino acids; 40746 Da
Subunit: Interacts with RWDD1 (By similarity)
Subcellular location: Cytoplasm
Secondary accessions: B2R8G5 Q53Y50 Q9BWB2

Explore the universe of human proteins at neXtProt for DRG2: NX_P55039

Explore proteomics data for DRG2 at MOPED 

Post-translational modifications:

  • UniProtKB: Polyubiquitinated; which induces proteolytic degradation and is impaired by interaction with RWDD1 (By similarity)
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P55039

  • DRG2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    DRG2 Protein Expression
    REFSEQ proteins: NP_001379.1  
    ENSEMBL proteins: 
     ENSP00000225729   ENSP00000462978   ENSP00000379076   ENSP00000464004   ENSP00000464076  
     ENSP00000463747   ENSP00000463268   ENSP00000463522   ENSP00000464244   ENSP00000463436  
     ENSP00000462060   ENSP00000463256  

    Human Recombinant Protein Products for DRG2: 
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    Novus Biologicals DRG2 Protein
    Novus Biologicals DRG2 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for DRG2 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IDA--
    GO:0005739mitochondrion IEA--
    GO:0016021integral to membrane ----

    DRG2 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    5/6 InterPro protein domains (see all 6):
     IPR027417 P-loop_NTPase
     IPR005225 Small_GTP-bd_dom
     IPR012676 TGS-like
     IPR006073 GTP_binding_domain
     IPR004095 TGS

    Graphical View of Domain Structure for InterPro Entry P55039

    ProtoNet protein and cluster: P55039

    2 Blocks protein domains:
    IPB002917 GTP-binding protein
    IPB006073 GTP1/OBG GTP-binding protein family signature


    UniProtKB/Swiss-Prot: DRG2_HUMAN, P55039
    Similarity: Belongs to the GTP1/OBG family
    Similarity: Contains 1 G (guanine nucleotide-binding) domain


    DRG2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: DRG2_HUMAN, P55039
    Function: May play a role in cell proliferation, differentiation and death

         Genatlas biochemistry entry for DRG2:
    developmentally regulated GTP-binding protein,41kDa,expressed in normal but not virally transformed fibroblasts

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005525GTP binding IEA--
    GO:0015093ferrous iron transmembrane transporter activity ----
         
    DRG2 for ontologies           About GeneDecksing


    Phenotypes:
         4 GenomeRNAi human phenotypes for DRG2:
     Decreased NANOG protein expres  Decreased OCT4 protein express  Decreased POU5F1-GFP protein e  Decreased homologous recombina 

         3 MGI mutant phenotypes (inferred from 1 allele(MGI details for Drg2):
     behavior/neurological  growth/size  limbs/digits/tail 

    DRG2 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for DRG2 
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for DRG2 
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    6 QIAGEN miScript miRNA Assays for microRNAs that regulate DRG2:
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    SwitchGear 3'UTR luciferase reporter plasmidDRG2 3' UTR sequence
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DRG2


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section




    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for DRG2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 8)

    5/28 Interacting proteins for DRG2 (P550392, 3 ENSP000002257294) via UniProtKB, MINT, STRING, and/or I2D (see all 28)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RWDD1Q9H4462, 3, ENSP000004203574MINT-67842 I2D: score=5 STRING: ENSP00000420357
    RUVBL2Q9Y2303, ENSP000002214134I2D: score=3 STRING: ENSP00000221413
    DRG1Q9Y2953, ENSP000003297154I2D: score=1 STRING: ENSP00000329715
    ENSG00000258947Q135093I2D: score=1 
    TUBB3Q135093I2D: score=1 
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007165signal transduction TAS7929244
    GO:0015684ferrous iron transport ----

    DRG2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for DRG2

    1 HMDB Compound for DRG2    About this table
    CompoundSynonyms CAS #PubMed Ids
    Guanosine triphosphate5'-GTP (see all 10)86-01-1--

    Search CenterWatch for drugs/clinical trials and news about DRG2

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for DRG2 gene: 
    NM_001388.4  

    Unigene Cluster for DRG2:

    Developmentally regulated GTP binding protein 2
    Hs.78582  [show with all ESTs]
    Unigene Representative Sequence: AB209340
    18/21 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 21):
    ENST00000225729(uc002gsh.1) ENST00000577771 ENST00000496428 ENST00000395726
    ENST00000578173 ENST00000582314 ENST00000579601 ENST00000473213 ENST00000578767
    ENST00000582419 ENST00000580055 ENST00000467099(uc010vxg.1) ENST00000579224
    ENST00000584212 ENST00000577450 ENST00000580929 ENST00000583162 ENST00000583355

    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
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    6 QIAGEN miScript miRNA Assays for microRNAs that regulate DRG2:
    hsa-miR-24-2* hsa-miR-24-1* hsa-miR-205* hsa-miR-1207-5p hsa-miR-3612 hsa-miR-650
    SwitchGear 3'UTR luciferase reporter plasmidDRG2 3' UTR sequence
    Inhib. RNA
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    Additional mRNA sequence: 

    AB209340.1 AK095755.1 AK295575.1 AK297569.1 AK313362.1 BC000493.2 BC062572.1 BT006976.1 
    X80754.1 

    16 DOTS entries:

    DT.95125858  DT.415782  DT.91883037  DT.95359910  DT.100809752  DT.99943033  DT.99935550  DT.95125862 
    DT.100809747  DT.120974914  DT.92441378  DT.100724162  DT.100809746  DT.100809748  DT.120974920  DT.120975006 

    24/309 AceView cDNA sequences (see all 309):

    BQ706376 CD514010 CB240882 BI765034 CR613675 NM_016239 AA732361 BQ691017 
    AA405448 BI909797 AU141267 BM967162 BG250562 BU689188 CA444541 CR591061 
    CA393006 CR602137 BP374416 X80754 CR610770 AW594545 AW016504 BM924541 

    GeneLoc Exon Structure

    5/10 Alternative Splicing Database (ASD) splice patterns (SP) for DRG2 (see all 10)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b ^ 3a · 3b · 3c · 3d ^ 4a · 4b · 4c · 4d ^ 5a · 5b · 5c ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12a · 12b ^ 13
    SP1:                                -     -           -     -           -     -     -           -     -                                         -               
    SP2:                                                  -     -                                                                                   -               
    SP3:                                -     -           -     -           -     -     -                                                                           
    SP4:                                -     -           -     -                 -     -                                                                           
    SP5:                                -     -           -     -                                                                                                   


    ECgene alternative splicing isoforms for DRG2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    DRG2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ATGGGAACCA
    DRG2 Expression
    About this image


    See DRG2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for DRG2

    SOURCE GeneReport for Unigene cluster: Hs.78582

    UniProtKB/Swiss-Prot: DRG2_HUMAN, P55039
    Tissue specificity: Highest levels in skeletal muscle, heart and kidney. Low levels in colon, thymus, spleen,
    small intestine, lung and Leukocytes

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for DRG2 gene from 10/24 species (see all 24)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Drg21 , 5 developmentally regulated GTP binding protein 21, 5 90.93(n)1
    98.63(a)1
      11 (37.81 cM)5
    134951  NM_021354.11  NP_067329.11 
     604545915 
    chicken
    (Gallus gallus)
    Aves DRG21 developmentally regulated GTP binding protein 2 81.23(n)
    96.98(a)
      416513  NM_001030634.1  NP_001025805.1 
    lizard
    (Anolis carolinensis)
    Reptilia DRG26
    Uncharacterized protein
    95(a)
    1 ↔ 1
    GL343977.1(15128-31123)
    African clawed frog
    (Xenopus laevis)
    Amphibia MGC691362 developmentally regulated GTP binding protein 2 79.5(n)    AB104728.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufb96a092 Danio rerio clone RK115A3G01 developmentally regulated more 77.79(n)    AY398336.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG61951 , 3 GTP binding3
    CG61951
    80(a)3
    73.09(n)1
    80.72(a)1
      423431  NM_142565.31  NP_650822.11 
    worm
    (Caenorhabditis elegans)
    Secernentea C02F5.31 , 3 GTP-binding protein3
    Protein C02F5.31
    74(a)3
    63.83(n)1
    75.55(a)1
      III(8317627-8320389)3
    1761631  NM_066407.41  NP_498808.21 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes RBG2(YGR173W)4
    RBG21
    Protein with a role in translation; forms a complex more4
    Rbg2p1
    57.05(n)1
    59.34(a)1
      7(843854-844960)4
    8530831, 4  NP_011689.11, 4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons DRG11 developmentally regulated G-protein 1 62.64(n)
    65.11(a)
      838320  NM_101609.3  NP_173190.1 
    rice
    (Oryza sativa)
    Liliopsida Os.72012 Oryza sativa (japonica cultivar-group) cDNA clone0 more 74.15(n)    AK105299.1 


    ENSEMBL Gene Tree for DRG2 (if available)
    TreeFam Gene Tree for DRG2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for DRG2 gene
    6 SIMAP similar genes for DRG2 using alignment to 10 protein entries:     DRG2_HUMAN (see all proteins):
    COX7A2    MTA3    NUSAP1    ZNF738    DRG1    DKFZp434N1827

    DRG2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/448 SNPs in DRG2 are shown (see all 448)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1901705761,2
    --17742736(+) TCCCTA/TCTTAC 1 -- us2k10--------
    rs1490356851,2
    C--17742746(+) CCCCC-/TGGCCA 1 -- us2k10--------
    rs1420118381,2
    --17989327(+) TAATCA/CTAGCA 1 -- us2k10--------
    rs1181652321,2
    C,F--17989357(+) GAGGAC/ATGCTT 1 -- us2k11Minor allele frequency- A:0.09EA 120
    rs43653461,2
    C--17989373(+) caggaG/Tttcag 1 -- us2k15Minor allele frequency- T:0.42NA CSA WA EA 361
    rs603661171,2
    --17989388(+) AGCCTG/AGGCAA 1 -- us2k11Minor allele frequency- A:0.01EA 120
    rs1929818881,2
    --17989393(+) GGGCAA/GCATAG 1 -- us2k10--------
    rs2013974381,2
    --17989415(+) TCTAC-/AAAAAA 1 -- us2k10--------
    rs43492031,2
    C,A,H--17989425(+) aaaaaT/Attttt 1 -- us2k13Minor allele frequency- A:0.49NA EA 244
    rs1848676851,2
    --17989426(+) AAAATA/TTTTTT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for DRG2 (17991200 - 18011292 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for DRG2:    About this table     
    Variant IDTypeSubtypePubMed ID
    dgv3077n71CNV Loss21882294
    nsv457697CNV Loss19166990
    nsv907769CNV Loss21882294
    nsv155OTHER Inversion15895083
    nsv499114OTHER Inversion21111241

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 602986    OMIM disorders: --

    2 diseases for DRG2:    About MalaCards
    smith magenis syndrome    tuberculosis


    DRG2 for disorders           About GeneDecksing

    Genetic Association Database (GAD): DRG2
    Human Genome Epidemiology (HuGE) Navigator: DRG2 (1 document)

    Export disorders for DRG2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for DRG2 gene, integrated from 9 sources (see all 27):
    (articles sorted by number of sources associating them with DRG2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A novel GTP-binding protein which is selectively repressed in SV40 transformed fibroblasts. (PubMed id 7929244)1, 2, 3 Schenker T....Trueb B. (1994)
    2. Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (2010)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. Assignment of the gene for a developmentally regulated GTP-binding protein (DRG2) to human chromosome bands 17p13-->p12 by in situ hybridization. (PubMed id 9605870)1, 3 Schenker T. and Trueb B. (1997)
    6. DRG represents a family of two closely related GTP-binding proteins. (PubMed id 10760581)1, 9 Li B. and Trueeb B. (2000)
    7. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    8. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    9. A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
    10. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 1819 HGNC: 3030 AceView: DRG2andMYO15A Ensembl:ENSG00000108591 euGenes: HUgn1819
    ECgene: DRG2 H-InvDB: DRG2

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for DRG2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for DRG2 gene:
    Search GeneIP for patents involving DRG2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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