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DRD1 Gene

protein-coding GIFtS: 68

GC05M174800

dopamine receptor D1
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
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Aliases
DADR ^²
DRD1A ^²
OTTHUMP00000161116 ^²

Descriptions
dopamine receptor D1 ^²

External Ids
HGNC: 3020¹
Entrez Gene: 1812²
UniProtKB: P21728³
Ensembl: ENSG00000184845⁷

Search outside databases for aliases for DRD1 gene

Previous GC identifers: GC05M175180 GC05M175606 GC05M174803 GC05M174848

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for DRD1:

This gene encodes the D1 subtype of the dopamine receptor. The D1 subtype is the most abundant

dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates

adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate

neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor

D2-mediated events. Alternate transcription initiation sites result in two transcript variants of

this gene. [provided by RefSeq]

UniProtKB/Swiss-Prot: DRD1_HUMAN, P21728

Function: This is one of the five types (D1 to D5) of receptors for dopamine. The activity of this

receptor is mediated by G proteins which activate adenylyl cyclase

Gene Wiki entry for DRD1 (Dopamine_receptor_D1)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the DRD1 gene

Entrez Gene cytogenetic band: 5q35.1 Ensembl cytogenetic band: 5q35.2 HGNC cytogenetic band: 5q34-q35

DRD1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 5 GeneLoc Exon Structure

GeneLoc location for GC05M174800: (about GC identifiers)

Start:	174,800,281 bp from pter
End:	174,803,769 bp from pter
Size:	3,489 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000005.8 NT_023133.12

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: DRD1_HUMAN, P21728 (See protein sequence)

Recommended Name: D(1A) dopamine receptor

Size: 446 amino acids; 49293 Da

Subunit: Interacts with DNAJC14 via its C-terminus (By similarity). Interacts with DRD1IP

Subcellular location: Cell membrane; Multi-pass membrane protein (By similarity). Endoplasmic

reticulum membrane; Multi-pass membrane protein (By similarity). Note=Transport from the

endoplasmic reticulum to the cell surface is regulated by interaction with DNAJC14 (By similarity)

PDB structures from and Proteopedia :

1OZ5 (3D)

Secondary accessions: Q4QRJ0

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_000785.1

ENSEMBL proteins:

ENSP00000327652 ENSP00000377353

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Millipore Purified and/or Recombinant DRD1 Protein
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (Dopamine Receptor D1)
	Browse Abnova for Human Recombinant Proteins

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

5 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005624	membrane fraction	IEA	--
GO:0005783	endoplasmic reticulum	IEA	--
GO:0005789	endoplasmic reticulum membrane	IEA	--
GO:0005886	plasma membrane	IDA	11500503
GO:0005887	integral to plasma membrane	IC	2144334

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Antibodies for DRD1:

	Browse Antibodies Central at Invitrogen
	Millipore Mono- and Polyclonal Antibodies for the study of DRD1
	Sigma-Aldrich Antibodies for DRD1
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (Dopamine Receptor D1), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (DRD1)
	Novus Biologicals Antibodies for DRD1

Assays for DRD1:

	Invitrogen Assays for DRD1
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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Graphical View of Domain Structure for InterPro Entry P21728

ProtoNet protein and cluster: P21728

2 Blocks protein families:

IPB000929 Dopamine receptor signature

IPB001413 Dopamine 1A receptor signature

UniProtKB/Swiss-Prot: DRD1_HUMAN, P21728

Similarity: Belongs to the G-protein coupled receptor 1 family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (DRD1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (DRD1)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_000794

Applied Biosystems Silencer® siRNAs for DRD1

Sigma-Aldrich siRNA and siRNA Panels for DRD1

Sigma-Aldrich shRNA Panels and shRNA for DRD1

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for DRD1
		Millipore Clones for the Expression of DRD1

OriGene GFP tagged cDNA clone in CMV expression vector: NM_000794
Myc/DDK tagged cDNA clone in CMV expression vector: NM_000794
untagged cDNA clone in CMV expression vector: NM_000794

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_000794

UniProtKB/Swiss-Prot: DRD1_HUMAN, P21728

Function: This is one of the five types (D1 to D5) of receptors for dopamine. The activity of this

receptor is mediated by G proteins which activate adenylyl cyclase

Genatlas biochemistry entry for DRD1:

dopamine receptor D1,mainly expressed in hypophysis and parathyroid in ovary and granulosa luteal

cells,adenylate cyclase stimulating,G protein coupled receptor superfamily,involved in the control

of vascular tone

11 MGI mutant phenotypes (inferred from 6 alleles) (MGI details for Drd1a):

behavior/neurological	growth/size	homeostasis/metabolism	immune system	lethality-postnatal
life span-post-weaning/aging	muscle	nervous system	normal	respiratory system
skin/coat/nails

4 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0001590	dopamine D1 receptor activity	IEA	--
GO:0004872	receptor activity	IEA	--
GO:0004930	G-protein coupled receptor activity	IEA	--
GO:0005515	protein binding	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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4 Sigma-Aldrich "Your Favorite Gene" Pathways for DRD1 (Your Favorite Gene powered by Ingenuity)

G-Protein Coupled Receptor Signaling
CDK5 Signaling
Dopamine Receptor Signaling
cAMP-mediated Signaling

GeneDecks DRD1 for the pathways selected above

About GeneDecksing

Gene Network Central^TM Interacting Genes and Proteins Network for DRD1

5/37 Interacting proteins for DRD1 (ENSP00000327652³) via UniProtKB, MINT, and/or STRING (see all 37 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
DNAJC14	ENSP00000316240³	STRING (score=.98)
PPP1R1B	ENSP00000254079³	STRING (score=.976)
CALY	ENSP00000252939³	STRING (score=.969)
GNAL	ENSP00000334051³	STRING (score=.962)
GNAS	ENSP00000302237³	STRING (score=.948)

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5/25 Gene Ontology (GO) biological process terms (links to tree view) (see all 25 ):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0001975	response to amphetamine	IEA	--
GO:0007165	signal transduction	IEA	--
GO:0007187	G-protein signaling, coupled to cyclic nucleotide second messenger	IDA	1282671
GO:0007191	activation of adenylate cyclase activity by dopamine receptor signaling pathway	IEA	--
GO:0007416	synaptogenesis	ISS	--

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Enzo Life Sciences drugs & compounds for DRD1

Sigma-Aldrich Small Molecules for DRD1:

Metabolite Antagonist Blocker Agonist Inhibitor

Compounds for DRD1 available from Tocris Bioscience

Compound	Action	CAS number
Fenoldopam hydrochloride	Selective D1-like partial agonist	[67227-56-9]
Dihydrexidine hydrochloride	Selective D1-like agonist	[123039-93-0]
SCH 23390 hydrochloride	Standard selective D1-like antagonist. Also 5-HT2C agonist	[125941-87-9]
SKF 81297 hydrobromide	D1 agonist	[71636-61-8]

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10/20 Novoseek chemical compound relationships for DRD1 gene (see all 20 )

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
skf-83959	78.91	1	16771826 (1)
forskolin	53.75	7	8853375 (1), 10082211 (1), 15255946 (1), 12417592 (1) (see all 6)
cyclic amp	51.65	15	8223965 (3), 10082211 (1), 10366011 (1), 8978703 (1) (see all 12)
ethylamine	38.54	1	7608904 (1)
n6-cyclopentyladenosine	35.21	4	16956604 (2), 9468534 (1)
ipsp	24.62	1	8593741 (1)
dopac	24.25	1	10683111 (1)
catecholamine	21.42	4	17353515 (1), 1355478 (1), 9920182 (1)
8-bromo-cyclic amp	19.36	1	8853375 (1)
tyrosine	15.42	5	10101226 (1), 17353515 (1), 18381284 (1), 9364244 (1) (see all 5)

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2 PharmGKB drug compound relationships for DRD1 gene

Drug compound	PharmGKB Relations	PubMed IDs for articles supporting these relationships
clozapine	PD	12351588
cocaine	FA	11543872

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (DRD1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (DRD1)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_000794

Sigma-Aldrich siRNA and siRNA Panels for DRD1

Sigma-Aldrich shRNA Panels and shRNA for DRD1

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_000794

REFSEQ mRNAs for DRD1 gene:

NM_000794.3

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_000794

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_000794
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_000794
                                 untagged cDNA clone in CMV expression vector: NM_000794

Additional cDNA sequence:

AF498961.1 AK314031.1 BC074978.2 BC074979.2 BC096837.1 CR541922.1 X58987.1

1 DOTS entry:

DT.308039

13 AceView cDNA sequences:

BM690062 AF498961 CR541922 NM_000794 CK903140 BC074978 X58987 BC074979

CB565882 CA950381 BV183492 BV183491 BM661781

highest scoring ESTs for DRD1:

X58987 AF498961 BM690062 CA950381 CB565882 CK903140 NM_000794 BC074978 BC074979 BC096837

Unigene Cluster for DRD1:

Dopamine receptor D1

Hs.2624 [show with all ESTs]

Unigene Representative Sequence: NM_000794

GeneLoc Exon Structure

2 Ensembl transcripts including schematic representations:

ENST00000329144 ENST00000393752

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

DRD1 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for DRD1

¹ / ² / ³

3 probe-sets matching DRD1 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
34550_at²^{, 3}	U95-A	1	1.00	1.00	1.00	1.00	X58987	0.80	1.00	0.91	1
214652_at²^{, 3}	U133-A	1	1.00	1.00	--	--	X58987	0.80	1.00	0.91	1
214652_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: TGTCAGGTAG

SOURCE GeneReport for Unigene cluster: Hs.2624
UniProtKB/Swiss-Prot: DRD1_HUMAN, P21728
Tissue specificity: Detected in caudate, nucleus accumbens and in the olfactory tubercle

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for DRD1 gene from 5/8 species (see all 8 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	DRD1¹	--	dopamine receptor D1	91.85(n) 95.52(a)	489110 XM_546227.2 XP_546227.2
cow (Bos taurus)	DRD1¹	--	dopamine receptor D1	91.03(n) 94.39(a)	281125 NM_174042.2 NP_776467.1
rat (Rattus norvegicus)	Drd1a¹	--	dopamine receptor D1A	86.2(n) 91.4(a)	24316 NM_012546.1 NP_036678.1
mouse (Mus musculus)	Drd1a^{1, 5}	13 (32.00 cM)⁵	dopamine receptor D1A^{1, 5}	87.03(n)¹ 91.86(a)¹	13488¹ NM_010076.2¹ NP_034206.1¹ AF171079⁵ AK021124⁵ (see all 13)
chicken (Gallus gallus)	DRD1¹	--	dopamine receptor D1	77.4(n) 82.66(a)	427633 XM_425206.2 XP_425206.1

About this table Species with no ortholog for DRD1

ENSEMBL Gene Tree for DRD1

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for DRD1 gene

DRD5² DRD5P2²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/37 NCBI SNPs in DRD1 are shown (see all 37 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 58)

AB	SNP ID	Valid	Chr 5 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
--	rs686^1,2	A,C,F,H	174801306(+)	`AGCAAA/GCCCCA`	1	--	ut3¹		7		NA EU EA WA	550
	rs265981^1,2	A,C,F,H	174803508(+)	`GCGGCG/AGCCCA`	1	--	ut5¹ ese³		9		EA NA EU WA	697
	rs4867798^1,2	A,C,F,H	174800505(+)	`ACTTTT/CTTAAA`	1	--	ut3¹		8		EU EA WA	806
--	rs5327^1,2	C,F,H	174802600(-)	`TGTCCA/CSGCTC`	1	T/P	mis¹		11		MN CSAM EA EU WA	1088
--	rs5328^1,2	C,F,H	174802599(-)	`GTCCMC/GGCTCC`	1	T/R	mis¹ ese³		15		MN CSAM EA EU WA	1508
	rs4532^1,2	C,F,H	174802756(+)	`GTTCCT/CAAGCA`	1	--	ut5¹		11		MN EU EA WA CSAM	1142
	rs10078866^1,2	A,C,H	174804926(+)	`AAGTCA/GCACAG`	1	--	ng3¹		4		EU EA WA	420
	rs5326^1,2	C,F,H	174802802(-)	`TGCCTG/AGTGGG`	1	--	ut5¹		15		MN CSAM EA EU WA	1504
	rs10063995^1,2	A,C	174804810(+)	`TCCCCG/TGTGCA`	1	--	ng3¹		0	--	--	--	--
	rs5330^1,2	C,H	174802559(-)	`ATCAGG/TTTCCG`	1	R/S	mis¹ ese³		11		MN CSAM EA EU WA	1078

About this table

HapMap Linkage Disequilibrium images for DRD1 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 126449

10/31 Novoseek disease relationships for DRD1 gene (see all 31 )

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
calcyon	81.08	10	11567648 (6), 14534309 (1), 12853145 (1), 10698743 (1)
schizophrenia	58.77	31	9024661 (2), 17455212 (2), 16397404 (2), 8837716 (2) (see all 24)
parkinson disease	58.64	20	16840977 (2), 8505636 (2), 10401786 (2), 8558425 (1) (see all 17)
cerebral meningioma	57.12	5	1385626 (4), 8869066 (1)
attention-deficit hyperactivity disorder	51.17	2	9613858 (1), 14569274 (1)
neuroepithelioma	41.88	1	16595738 (1)
catalepsy	38.35	2	1975782 (1), 2154287 (1)
huntington disease	37.96	2	8172940 (2)
bipolar disorder	36.74	19	12488059 (4), 16397404 (3), 1385598 (2), 8837716 (2) (see all 9)
parkinsonism	33.46	4	14698740 (1), 8864687 (1), 8098860 (1)

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2 PharmGKB disease relationships for DRD1 gene

Disease	PharmGKB Relations	PubMed IDs for articles supporting these relationships
Mental Disorders	GN	9613858
Schizophrenia	PD GN	12351588 9613858

About this table

Human Gene Mutation Database: DRD1
Genetic Association Database: DRD1
Human Genome Epidemiology Navigator: DRD1 (55 documents)

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/360 PubMed articles for DRD1 gene (see all 360 ):

Association analysis between Tourette's syndrome and dopamine D1 receptor gene in Taiwanese children. (PubMed id 15564897)^{1, 3, 6} Chou I.C....Tsai F.J. (2004)
Molecular cloning and expression of the gene for a human D1 dopamine receptor. (PubMed id 2144334)^{1, 3, 4} Dearry A....Caron M.G. (1990)
Cloning and expression of human and rat D1 dopamine receptors. (PubMed id 2168520)^{1, 3, 4} Zhou Q.-Y.... Civelli O. (1990)
A48G polymorphism in the D1 receptor genes associated with bipolar I disorder. (PubMed id 15704231)^{1, 3, 6} Severino G....Piccardi M.P. (2005)
Analysis of SNP profiles in patients with major depressive disorder. (PubMed id 15927089)^{1, 3, 6} Koks S....Vasar E. (2006)
An association study of dopamine receptors polymorphisms and the Wisconsin Card Sorting Test in schizophrenia. (PubMed id 15785860)^{1, 3, 6} Rybakowski J.K....Hauser J. (2005)
Ethnic origin determines the impact of genetic variants in dopamine receptor gene (DRD1) concerning essential hypertension. (PubMed id 15607627)^{1, 3, 6} Beige J....Gessner R. (2004)
Association study between the phenotype migraine without aura-panic disorder and dopaminergic receptor genes. (PubMed id 12967601)^{1, 3, 6} Stochino M.E....Severino G. (2003)
Psychosis and aggression in Alzheimer's disease: the effect of dopamine receptor gene variation. (PubMed id 11723200)^{1, 3, 6} Holmes C....Lovestone S. (2001)
Schizophrenia: dopamine D1 receptor sequence is normal, but has DNA polymorphisms. (PubMed id 8471124)^{1, 3, 4} Ohara K....Niznik H.B. (1993)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 1812	HGNC: 3020	AceView: DRD1	Ensembl:ENSG00000184845	euGenes: HUgn1812
ECgene: DRD1	H-InvDB: DRD1

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Licensable Technologies for DRD1
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for DRD1:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for DRD1-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for DRD1		Antibodies for DRD1
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for DRD1		Small molecules for DRD1
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Search for Recombinant Proteins
	Antibodies (DRD1)
	Chimera RNAi (DRD1)
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	Custom Service for Rabbit Pab from Full-length Protein

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	Recombinant Proteins (Dopamine Receptor D1)
	Antibodies (Dopamine Receptor D1)

Search OriGene for DRD1

Tocris compounds for DRD1

	Drugs for DRD1
	Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for DRD1

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DRD1 Gene

protein-coding GIFtS: 68

Aliases &
Descriptions
for DRD1

Summaries
for DRD1

Genomic Location
for DRD1

Proteins
for DRD1

Protein Domains/
Families
for DRD1

Gene Function
for DRD1

Pathways & Interactions
for DRD1

Drugs & Compounds
for DRD1

Transcripts
for DRD1

Expression
for DRD1

Orthologs
for DRD1

Paralogs
for DRD1

SNPs/Variants
for DRD1

Disorders & Mutations
for DRD1

Medical News
for DRD1

Publications
for DRD1

Search for DRD1

Genome Databases showing DRD1

Other Databases showing DRD1

Specialized Databases showing DRD1

Licensable Technologies
for DRD1

Services
for DRD1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

DRD1 Gene

protein-coding GIFtS: 68

Aliases & Descriptionsfor DRD1

Summariesfor DRD1

Genomic Locationfor DRD1

Proteinsfor DRD1

Protein Domains/Familiesfor DRD1

Gene Functionfor DRD1

Pathways & Interactionsfor DRD1

Drugs & Compoundsfor DRD1

Transcriptsfor DRD1

Expression for DRD1

Orthologsfor DRD1

Paralogsfor DRD1

SNPs/Variantsfor DRD1

Disorders & Mutationsfor DRD1

Medical Newsfor DRD1

Publicationsfor DRD1

Search for DRD1

Genome Databases showing DRD1

Other Databases showing DRD1

Specialized Databases showing DRD1

Licensable Technologiesfor DRD1

Servicesfor DRD1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for DRD1

Summaries
for DRD1

Genomic Location
for DRD1

Proteins
for DRD1

Protein Domains/
Families
for DRD1

Gene Function
for DRD1

Pathways & Interactions
for DRD1

Drugs & Compounds
for DRD1

Transcripts
for DRD1

Expression
for DRD1

Orthologs
for DRD1

Paralogs
for DRD1

SNPs/Variants
for DRD1

Disorders & Mutations
for DRD1

Medical News
for DRD1

Publications
for DRD1

Licensable Technologies
for DRD1

Services
for DRD1