Aliases for DRC1 Gene
External Ids for DRC1 Gene
Previous HGNC Symbols for DRC1 Gene
Previous GeneCards Identifiers for DRC1 Gene
This gene encodes a central component of the nexin-dynein complex (N-DRC), which regulates the assembly of ciliary dynein. Mutations in this gene can cause ciliary dyskinesia. [provided by RefSeq, Aug 2015]
GeneCards Summary for DRC1 Gene
DRC1 (Dynein Regulatory Complex Subunit 1) is a Protein Coding gene. Diseases associated with DRC1 include Ciliary Dyskinesia, Primary, 21 and Ciliary Dyskinesia, Primary, 1, With Or Without Situs Inversus.
UniProtKB/Swiss-Prot for DRC1 Gene
Key component of the nexin-dynein regulatory complex (N-DRC), essential for N-DRC integrity. Required for the assembly and regulation of specific classes of inner dynein arm motors. May also function to restrict dynein-driven microtubule sliding, thus aiding in the generation of ciliary bending.