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DRAP1 Gene

protein-coding   GIFtS: 58
GCID: GC11P065686

DR1-Associated Protein 1 (Negative Cofactor 2 Alpha)

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
DR1-Associated Protein 1 (Negative Cofactor 2 Alpha)1 2     NC2-alpha2 3
DR1-Associated Corepressor1 2     Negative Co-Factor 2-Alpha2
Negative Cofactor 2 Alpha1 2     Dr1-Associated Protein 13
Negative Cofactor 2-Alpha2 3     

External Ids:    HGNC: 30191   Entrez Gene: 105892   Ensembl: ENSG000001755507   OMIM: 6022895   UniProtKB: Q149193   
ORGUL members:         

Export aliases for DRAP1 gene to outside databases

Previous GC identifers: GC11P068221 GC11P067368 GC11P065936 GC11P065462 GC11P065443 GC11P062013


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for DRAP1 Gene:
Transcriptional repression is a general mechanism for regulating transcriptional initiation in organisms ranging
from yeast to humans. Accurate initiation of transcription from eukaryotic protein-encoding genes requires the
assembly of a large multiprotein complex consisting of RNA polymerase II and general transcription factors such
as TFIIA, TFIIB, and TFIID. DR1 is a repressor that interacts with the TATA-binding protein (TBP) of TFIID and
prevents the formation of an active transcription complex by precluding the entry of TFIIA and/or TFIIB into the
preinitiation complex. The protein encoded by this gene is a corepressor of transcription that interacts with DR1
to enhance DR1-mediated repression. The interaction between this corepressor and DR1 is required for corepressor
function and appears to stabilize the TBP-DR1-DNA complex. (provided by RefSeq, Jul 2008)

GeneCards Summary for DRAP1 Gene:
DRAP1 (DR1-associated protein 1 (negative cofactor 2 alpha)) is a protein-coding gene. GO annotations related to this gene include protein heterodimerization activity and sequence-specific DNA binding transcription factor activity.

UniProtKB/Swiss-Prot: NC2A_HUMAN, Q14919
Function: The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both
activated and basal transcription of class II genes. This interaction precludes the formation of a
transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on
its own

Gene Wiki entry for DRAP1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000011.9  NC_018922.2  NT_167190.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the DRAP1 gene promoter:
         CRE-BP1   TBP   STAT1   p53   ATF-2   p300   C/EBPalpha   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for DRAP1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat DRAP1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q13.3   Ensembl cytogenetic band:  11q13.1   HGNC cytogenetic band: 11q13

DRAP1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DRAP1 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11P065686:  view genomic region     (about GC identifiers)

Start:
65,686,728 bp from pter      End:
65,689,048 bp from pter
Size:
2,321 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: NC2A_HUMAN, Q14919 (See protein sequence)
Recommended Name: Dr1-associated corepressor  
Size: 205 amino acids; 22350 Da
Subunit: Heterodimer with DR1. Binds BTAF1
1 PDB 3D structure from and Proteopedia for DRAP1:
1JFI (3D)    
Secondary accessions: Q13448
Alternative splicing: 2 isoforms:  Q14919-1   Q14919-2   

Explore the universe of human proteins at neXtProt for DRAP1: NX_Q14919

Explore proteomics data for DRAP1 at MOPED

Post-translational modifications: 

  • Phosphorylation reduces DNA binding, but has no effect on heterodimerization and TBP binding1
  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See DRAP1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_006433.2  
    ENSEMBL proteins: 
     ENSP00000307850   ENSP00000437225   ENSP00000366190   ENSP00000437287   ENSP00000432445  
    Reactome Protein details: Q14919

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR003958 CBFA_NFYB_domain
     IPR009072 Histone-fold

    Graphical View of Domain Structure for InterPro Entry Q14919

    ProtoNet protein and cluster: Q14919

    1 Blocks protein domain: IPB003958 Transcription factor CBF/NF-Y/archaeal histone

    UniProtKB/Swiss-Prot: NC2A_HUMAN, Q14919
    Similarity: Belongs to the NC2 alpha/DRAP1 family
    Similarity: Contains 1 histone-fold domain


    Find genes that share domains with DRAP1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NC2A_HUMAN, Q14919
    Function: The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both
    activated and basal transcription of class II genes. This interaction precludes the formation of a
    transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on
    its own

         Genatlas biochemistry entry for DRAP1:
    Dr1-associated polypeptide,corepressor of transcription,expressed with higher levels in tissues with low mitotic
    index

         Gene Ontology (GO): Selected molecular function terms (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding TAS8670811
    GO:0003700sequence-specific DNA binding transcription factor activity TAS8608938
    GO:0003714transcription corepressor activity IEA--
    GO:0005515protein binding IPI16189514
    GO:0008134transcription factor binding IEA--
         
    Find genes that share ontologies with DRAP1           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for DRAP1:
     Increased S DNA content 

         2 MGI mutant phenotypes (inferred from 1 allele(MGI details for Drap1):
     embryogenesis  mortality/aging 

    Find genes that share phenotypes with DRAP1           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out Drap1tm1Mms for DRAP1

       genOway: Develop your customized and physiologically relevant rodent model for DRAP1

    miRNA
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    miRTarBase miRNAs that target DRAP1:
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    NC2A_HUMAN, Q14919: Nucleus (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    plasma membrane2
    cytosol1
    endoplasmic reticulum1
    mitochondrion1
    peroxisome1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005634nucleus IEA--

    Find genes that share ontologies with DRAP1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for DRAP1 About    
    See pathways by source

    SuperPathContained pathways About
    1Signaling by NODAL
    Signaling by NODAL0.39
    Signaling by Activin0.39
    2L1CAM interactions
    Developmental Biology0.63
    3Signaling by GPCR
    Signal Transduction0.58


    Find genes that share SuperPaths with DRAP1           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    2 Reactome Pathways for DRAP1
        Signaling by Activin
    Signaling by NODAL


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for DRAP1
    Interactions:

        GeneGlobe Interaction Network for DRAP1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for DRAP1 (Q149191, 2, 3 ENSP000003078504) via UniProtKB, MINT, STRING, and/or I2D (see all 62)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    NFYBP252082, 3, ENSP000002400554MINT-66211 I2D: score=5 STRING: ENSP00000240055
    TAF9BQ9HBM62, 3, ENSP000003399174MINT-68182 I2D: score=5 STRING: ENSP00000339917
    DNAJB11Q9UBS42, 3, ENSP000002650284MINT-8254232 I2D: score=2 STRING: ENSP00000265028
    TNFRSF14Q929562, 3, ENSP000003479484MINT-8274478 I2D: score=2 STRING: ENSP00000347948
    TK1P041832, 3MINT-63370 I2D: score=5 
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000122negative regulation of transcription from RNA polymerase II promoter IEA--
    GO:0006351transcription, DNA-templated IEA--

    Find genes that share ontologies with DRAP1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for DRAP1 (NC2A)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for DRAP1 gene: 
    NM_006442.3  

    Unigene Cluster for DRAP1:

    DR1-associated protein 1 (negative cofactor 2 alpha)
    Hs.356742  [show with all ESTs]
    Unigene Representative Sequence: BF969132
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000312515(uc001ogj.2) ENST00000525501 ENST00000376991 ENST00000531121
    ENST00000527119 ENST00000532933 ENST00000530791 ENST00000534333 ENST00000525190

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    hsa-miR-3658 hsa-miR-513a-3p hsa-miR-3653 hsa-miR-548b-3p hsa-miR-486-3p hsa-miR-548aa
    Browse SwitchGear 3'UTR luciferase reporter plasmids
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    Additional mRNA sequence: 

    BC010025.2 X96506.1 

    6 DOTS entries:

    DT.415022  DT.100780789  DT.97851987  DT.120759072  DT.102827508  DT.92427048 

    Selected AceView cDNA sequences (see all 266):

    AI753931 BQ689916 AI076130 BU633271 F37452 BM705246 BM841158 CK824883 
    BQ018267 BF345953 BM840479 BG395819 BM561293 CA448044 CA950374 BM981253 
    BC010025 NM_006442 BM555269 BQ690026 BQ014552 BQ686162 CF129614 AI879258 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for DRAP1    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b · 6c ^ 7a · 7b
    SP1:                    -                 -                                             
    SP2:                                      -                                             
    SP3:                    -                 -                                             
    SP4:                    -                 -                                             
    SP5:                                                                                    


    ECgene alternative splicing isoforms for DRAP1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    DRAP1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GATGGGGACA
    DRAP1 Expression
    About this image


    DRAP1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 8) fully expand
     
     Brain (Nervous System)
             Cerebral Cortex
     
     Thyroid (Endocrine System)
     
     Pancreas (Endocrine System)
     
     Testis (Reproductive System)
     
     Fibroblasts (Uncategorized)
    DRAP1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    DRAP1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.356742

    UniProtKB/Swiss-Prot: NC2A_HUMAN, Q14919
    Tissue specificity: Ubiquitous. Highly expressed in adult testis, heart, skeletal muscle, pancreas and brain, and
    in fetal brain, liver and kidney

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for DRAP1 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Drap11 , 5 Dr1 associated protein 1 (negative cofactor 2 alpha)1, 5 88.58(n)1
    93.92(a)1
      19 (4.32 cM)5
    665561  NM_024176.11  NP_077138.11 
     54228055 
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.237372 Xenopus laevis transcribed sequence with weak similarity more 75.49(n)    BJ617281.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.7192 Danio rerio mRNA similar to Dr1 associated protein more 79.96(n)    BC045853.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta NC2alpha3 negative regulation of transcriptional
    pre-initiation more
    64(a)   57F7   --
    worm
    (Caenorhabditis elegans)
    Secernentea drap-16
    Protein DRAP-1, isoform b (drap-1) mRNA, complete ...
    14(a)
    1 ↔ 1
    V(9730112-9734028) WBGene00009584
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes BUR6(YER159C)4 Subunit of a heterodimeric NC2 transcription regulator more   --   5(491958-491530) 856904  NP_011086.1 


    ENSEMBL Gene Tree for DRAP1 (if available)
    TreeFam Gene Tree for DRAP1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for DRAP1 (see all 40)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1842502271,2
    --65688601(+) TCTCCC/TGAAAG 1 -- int10--------
    rs778829621,2
    C,F--65688625(+) CTGCCA/GGGGCC 1 -- int12Minor allele frequency- G:0.10WA 120
    rs767180901,2
    C,F--65688694(+) CTGGAG/CGGTGG 1 -- int11Minor allele frequency- C:0.03WA 118
    rs2018716331,2
    C--65688818(+) CTTCCC/TGCCCT 2 P L mis10--------
    rs2011301481,2
    --65688825(+) CCCTTC/TGCCTC 2 F syn10--------
    rs2009054481,2
    --65688839(+) TCTGCC/TTTTGC 2 P L mis10--------
    rs1996040091,2
    --65688855(+) GCGCCA/CCCGGG 2 P syn10--------
    rs1442779261,2
    C--65688882(+) GAAGAG/CGACGA 2 /D /E mis11Minor allele frequency- C:0.00NA 4542
    rs2018278941,2
    --65688892(+) AAGAAA/GATTAC 2 N D mis10--------
    rs2009284751,2
    C--65688921(+) CCCCCC/GAGACC 1 -- ut310--------

    HapMap Linkage Disequilibrium report for DRAP1 (65686728 - 65689048 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for DRAP1:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv897767CNV Loss21882294
    nsv897764CNV Loss21882294
    nsv832191CNV Loss17160897
    dgv1185n71CNV Loss21882294
    dgv393e1CNV Complex17122850

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 602289    OMIM disorders: --


    Find genes that share disorders with DRAP1           About GenesLikeMe


    Export disorders for DRAP1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for DRAP1 gene, integrated from 10 sources (see all 34):
    (articles sorted by number of sources associating them with DRAP1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Requirement of a corepressor for Dr1-mediated repression of transcription. (PubMed id 8608938)1, 2, 3 Mermelstein F....Reinberg D. (Genes Dev. 1996)
    2. NC2alpha interacts with BTAF1 and stimulates its ATP-dependent association with TATA-binding protein. (PubMed id 15509807)1, 2, 9 Klejman M.P.... Timmers H.T.M. (Mol. Cell. Biol. 2004)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Crystal structure of negative cofactor 2 recognizing the TBP-DNA transcription complex. (PubMed id 11461703)1, 2 Kamada K.... Burley S.K. (Cell 2001)
    5. A mechanism for repression of class II gene transcription through specific binding of NC2 to TBP-promoter complexes via heterodimeric histone fold domains. (PubMed id 8670811)1, 2 Goppelt A.R.... Meisterernst M. (EMBO J. 1996)
    6. The protein interaction landscape of the human CMGC kinase group. (PubMed id 23602568)1 Varjosalo M....Gstaiger M. (Cell Rep 2013)
    7. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    8. A high-throughput approach for measuring temporal changes in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (Nat. Methods 2012)
    9. N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PubMed id 22814378)2 Van Damme P....Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012)
    10. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 10589 HGNC: 3019 AceView: DRAP1 Ensembl:ENSG00000175550 euGenes: HUgn10589
    ECgene: DRAP1 H-InvDB: DRAP1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for DRAP1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for DRAP1 gene:
    Search GeneIP for patents involving DRAP1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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