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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

DRAM1 Gene

protein-coding   GIFtS: 47
GCID: GC12P102271

DNA-Damage Regulated Autophagy Modulator 1

  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
DNA-Damage Regulated Autophagy Modulator 11 2
Damage-Regulated Autophagy Modulator1 2 3
DRAM2 3
DNA Damage-Regulated Autophagy Modulator Protein 12

External Ids:    HGNC: 256451   Entrez Gene: 553322   Ensembl: ENSG000001360487   OMIM: 6107765   UniProtKB: Q8N6823   

Export aliases for DRAM1 gene to outside databases

Previous GC identifers: GC12P100798 GC12P099330


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for DRAM1 Gene:
This gene is regulated as part of the p53 tumor suppressor pathway. The gene encodes a lysosomal membrane protein
that is required for the induction of autophagy by the pathway. Decreased transcriptional expression of this gene
is associated with various tumors. This gene has a pseudogene on chromosome 4. (provided by RefSeq, Jul 2008)

GeneCards Summary for DRAM1 Gene: 
DRAM1 (DNA-damage regulated autophagy modulator 1) is a protein-coding gene. Diseases associated with DRAM1 include sarcoma. An important paralog of this gene is DRAM2.

UniProtKB/Swiss-Prot: DRAM1_HUMAN, Q8N682
Function: Lysosomal modulator of autophagy that plays a central role in p53/TP53-mediated apoptosis. Not involved
in p73/TP73-mediated autophagy




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000012.11  NT_029419.12  NC_018923.2  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for DRAM1
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidDRAM1 promoter sequence
   Search SABiosciences Chromatin IP Primers for DRAM1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DRAM1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q23.2   Ensembl cytogenetic band:  12q23.2   HGNC cytogenetic band: 12q23.2

DRAM1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DRAM1 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12P102271:  view genomic region     (about GC identifiers)

Start:
102,271,105 bp from pter      End:
102,405,908 bp from pter
Size:
134,804 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: DRAM1_HUMAN, Q8N682 (See protein sequence)
Recommended Name: DNA damage-regulated autophagy modulator protein 1  
Size: 238 amino acids; 26253 Da
Subcellular location: Lysosome membrane; Multi-pass membrane protein
Sequence caution: Sequence=BAA92091.1; Type=Erroneous initiation;
Secondary accessions: Q7L3E3 Q9NUN1

Explore the universe of human proteins at neXtProt for DRAM1: NX_Q8N682

Explore proteomics data for DRAM1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8N682

  • DRAM1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    DRAM1 Protein Expression
    REFSEQ proteins: NP_060840.2  
    ENSEMBL proteins: 
     ENSP00000258534   ENSP00000445827   ENSP00000448075   ENSP00000447171   ENSP00000447906  

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    Browse Sino Biological Cell Lysates 
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    Cloud-Clone Corp. Proteins for DRAM1 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IDA19895784
    GO:0005764lysosome IDA19895784
    GO:0005765lysosomal membrane IEA--
    GO:0016021integral to membrane IEA--

    DRAM1 for ontologies           About GeneDecksing



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    Cloud-Clone Corp. CLIAs for DRAM1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR019402 Frag1/DRAM/Sfk1

    Graphical View of Domain Structure for InterPro Entry Q8N682

    ProtoNet protein and cluster: Q8N682

    UniProtKB/Swiss-Prot: DRAM1_HUMAN, Q8N682
    Similarity: Belongs to the DRAM/TMEM150 family


    DRAM1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: DRAM1_HUMAN, Q8N682
    Function: Lysosomal modulator of autophagy that plays a central role in p53/TP53-mediated apoptosis. Not involved
    in p73/TP73-mediated autophagy
    Induction: By p53/TP53 and p73/TP73. Directly activated by p53/TP53. Significantly down-regulated in tumor cell
    lines by methylation-dependent transcriptional silencing

    Phenotypes:
         1 GenomeRNAi human phenotype for DRAM1:

     Synthetic lethal with Ras 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for DRAM1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for DRAM1

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    miRTarBase miRNAs that target DRAM1:
    hsa-mir-124 (MIRT004906)

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    8/21 QIAGEN miScript miRNA Assays for microRNAs that regulate DRAM1 (see all 21):
    hsa-miR-136 hsa-miR-496 hsa-miR-1297 hsa-miR-124 hsa-miR-199b-5p hsa-miR-29a* hsa-miR-506 hsa-miR-28-5p
    SwitchGear 3'UTR luciferase reporter plasmidDRAM1 3' UTR sequence
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for DRAM1

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006914autophagy IEA--
    GO:0030262apoptotic nuclear changes IDA19895784
    GO:0097194execution phase of apoptosis IC19895784

    DRAM1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for DRAM1

    Search CenterWatch for drugs/clinical trials and news about DRAM1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for DRAM1 gene: 
    NM_018370.2  

    Unigene Cluster for DRAM1:

    DNA-damage regulated autophagy modulator 1
    Hs.525634  [show with all ESTs]
    Unigene Representative Sequence: NM_018370
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000258534(uc001tix.3 uc010svv.2) ENST00000544152 ENST00000551403
    ENST00000549365 ENST00000549066 ENST00000546729
    miRNA
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    hsa-miR-136 hsa-miR-496 hsa-miR-1297 hsa-miR-124 hsa-miR-199b-5p hsa-miR-29a* hsa-miR-506 hsa-miR-28-5p
    SwitchGear 3'UTR luciferase reporter plasmidDRAM1 3' UTR sequence
    Inhib. RNA
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    Additional mRNA sequence: 

    AK002121.1 AK094923.1 AK297785.1 BC013773.1 BC018435.1 

    9 DOTS entries:

    DT.213396  DT.86835766  DT.95353736  DT.99929399  DT.121152169  DT.121152337  DT.99938311  DT.100750270 
    DT.100750272 

    24/145 AceView cDNA sequences (see all 145):

    BM912860 BP352620 BM556097 BU628718 BG250630 CA307951 BM915334 BM915337 
    BQ951996 BM991570 AW449733 BC018435 BM763554 BQ669342 AI148797 BM562526 
    CD369496 BQ575801 BM913441 CA306171 BM997108 AI079438 AI304821 BQ641768 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for DRAM1    About this scheme

    ExUns: 1 ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7
    SP1:                                                
    SP2:                          -                     


    ECgene alternative splicing isoforms for DRAM1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    DRAM1 expression in normal human tissues (normalized intensities)      DRAM1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    DRAM1 Expression
    About this image


    DRAM1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/39 selected tissues (see all 39) fully expand
     
     Brain (Nervous System)    fully expand to see all 5 entries
             Cerebral Cortex
             optic nerve head astrocytes   
     
     Epithelium
             vagina ; squamous epithelial cells   
     
     Uterus (Reproductive System)    fully expand to see all 5 entries
             uterus, post-menopause ; glandular cells   
     
     Testis (Reproductive System)    fully expand to see all 4 entries
             Leydig Cells Testis Interstitium
             seminal vesicle ; glandular cells   
     
     Colon (Gastrointestinal Tract)    fully expand to see all 4 entries
             colon ; peripheral nerve/ganglion   

    See DRAM1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for DRAM1

    SOURCE GeneReport for Unigene cluster: Hs.525634
        SABiosciences Expression via Pathway-Focused PCR Array including DRAM1: 
              Autophagy in human mouse rat

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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for DRAM1 gene from 6/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Dram11 , 5 DNA-damage regulated autophagy modulator 11, 5 88.47(n)1
    94.94(a)1
      10 (43.81 cM)5
    717121  NM_027878.21  NP_082154.21 
     883228045 
    chicken
    (Gallus gallus)
    Aves DRAM11 DNA-damage regulated autophagy modulator 1 72.57(n)
    71.31(a)
      418095  XM_001234898.2  XP_001234899.2 
    lizard
    (Anolis carolinensis)
    Reptilia DRAM16
    Uncharacterized protein
    59(a)
    1 ↔ 1
    5(17451623-17474170)
    zebrafish
    (Danio rerio)
    Actinopterygii dram11 DNA-damage regulated autophagy modulator 1 55.27(n)
    47.86(a)
      450028  NM_001006049.1  NP_001006049.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG40256
    --
    34(a)
    1 → many
    X(1970999-1972488)
    worm
    (Caenorhabditis elegans)
    Secernentea C33A11.26
    Protein C33A11.2
    19(a)
    1 → many
    X(15365994-15370000)


    ENSEMBL Gene Tree for DRAM1 (if available)
    TreeFam Gene Tree for DRAM1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for DRAM1 gene
    DRAM22  
    1 SIMAP similar gene for DRAM1 using alignment to 4 protein entries:     DRAM1_HUMAN (see all proteins):
    DRAM2

    DRAM1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1265 SNPs in DRAM1 are shown (see all 1265)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs562781831,2
    C--99336367(+) TTTTT-/T/TT  
            
    GAAAT
    1 -- int12NA 4
    rs765855681,2
    C,F--102269314(+) TTGTAT/GGGCGG 1 -- us2k11Minor allele frequency- G:0.19EA 120
    rs111110661,2
    C,A--102269318(+) ATGGCG/AGGCAC 1 -- us2k14Minor allele frequency- A:0.12NA EA 244
    rs1407175931,2
    --102269333(+) TCCACA/GGCCAC 1 -- us2k10--------
    rs1898647861,2
    --102269511(+) TGTGTA/GTGCAT 1 -- us2k10--------
    rs1508358701,2
    C--102269524(+) CCTCC-/AGTTGT 1 -- us2k10--------
    rs108608041,2
    C,F,A,H--102269821(+) CTCCAT/CTTCCC 1 -- us2k13Minor allele frequency- C:0.28WA NA EA 358
    rs5361751,2
    --102269879(+) caggcA/Gtgagc 1 -- us2k10--------
    rs1453599661,2
    --102269903(+) TAATTA/TTTTGT 1 -- us2k10--------
    rs799305531,2
    C--102269980(+) TCCACC/TCACCT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for DRAM1 (102271105 - 102405908 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 9 variations for DRAM1:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv4264CNV Deletion18987735
    esv2665303CNV Deletion23128226
    esv2499618CNV Deletion19546169
    esv2746283CNV Deletion23290073
    dgv308e199CNV Deletion23128226
    esv2318192CNV Deletion18987734
    esv2746282CNV Deletion23290073
    esv2746281CNV Deletion23290073
    nsv899472CNV Gain21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 610776    OMIM disorders: --

    2 diseases for DRAM1:    About MalaCards
    sarcoma    


    DRAM1 for disorders           About GeneDecksing


    Export disorders for DRAM1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for DRAM1 gene, integrated from 9 sources (see all 20):
    (articles sorted by number of sources associating them with DRAM1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. DRAM, a p53-induced modulator of autophagy, is critical for apoptosis. (PubMed id 16839881)1, 2, 3 Crighton D.... Ryan K.M. (2006)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    3. Differential roles of miR-199a-5p in radiation-induced autophagy in breast cancer cells. (PubMed id 23337876)1 Yi H....Liu X. (2013)
    4. The autophagy-associated factors DRAM1 and p62 regulat e cell migration and invasion in glioblastoma stem cells. (PubMed id 22525272)1 Galavotti S....Salomoni P. (2013)
    5. Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lup us erythematosus in Asians. (PubMed id 23273568)1 Yang W....Lau Y.L. (2013)
    6. Inhibition of damage-regulated autophagy modulator-1 ( DRAM-1) impairs neutrophil differentiation of NB4 APL cells. (PubMed id 22981223)1 Humbert M....Tschan M.P. (2012)
    7. DRAM-1 encodes multiple isoforms that regulate autopha gy. (PubMed id 22082963)1 Mah L.Y....Ryan K.M. (2012)
    8. Downregulation of VRK1 by p53 in response to DNA dama ge is mediated by the autophagic pathway. (PubMed id 21386980)1 Valbuena A....Lazo P.A. (2011)
    9. Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (2011)
    10. c-Jun NH2-terminal kinase activation is essential for DRAM-dependent induction of autophagy and apoptosis in 2-methoxyestradiol-trea ted Ewing sarcoma cells. (PubMed id 19706754)1 Lorin S....Djavaheri-Mergny M. (2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 55332 HGNC: 25645 AceView: FLJ11259 Ensembl:ENSG00000136048 euGenes: HUgn55332
    ECgene: DRAM1 H-InvDB: DRAM1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for DRAM1 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for DRAM1 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for DRAM1 gene:
    Search GeneIP for patents involving DRAM1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     EMD Millipore Mono- and Polyclonal Antibodies for the study of DRAM1
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     Proteins for DRAM1
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     inGenious Targeting Laboratory - Custom generated mouse model solutions for DRAM1
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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    (GIFtS: 73)
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