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Aliases for DQX1 Gene

Aliases for DQX1 Gene

  • DEAQ Box RNA-Dependent ATPase 1 2 3
  • DEAQ Box Polypeptide 1 (RNA-Dependent ATPase) 2
  • DEAQ Box Polypeptide 1 4
  • EC 3.6.4.12 4

External Ids for DQX1 Gene

Summaries for DQX1 Gene

GeneCards Summary for DQX1 Gene

DQX1 (DEAQ Box RNA-Dependent ATPase 1) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding and helicase activity. An important paralog of this gene is DHX35.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for DQX1 Gene

Genomics for DQX1 Gene

Genomic Location for DQX1 Gene

Start:
74,518,131 bp from pter
End:
74,526,336 bp from pter
Size:
8,206 bases
Orientation:
Minus strand

Genomic View for DQX1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for DQX1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for DQX1 Gene

Regulatory Elements for DQX1 Gene

Proteins for DQX1 Gene

  • Protein details for DQX1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8TE96-DQX1_HUMAN
    Recommended name:
    ATP-dependent RNA helicase DQX1
    Protein Accession:
    Q8TE96
    Secondary Accessions:
    • Q6B017
    • Q8NAM8

    Protein attributes for DQX1 Gene

    Size:
    717 amino acids
    Molecular mass:
    79476 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for DQX1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for DQX1 Gene

Proteomics data for DQX1 Gene at MOPED

Post-translational modifications for DQX1 Gene

No Post-translational modifications

Other Protein References for DQX1 Gene

No data available for DME Specific Peptides for DQX1 Gene

Domains for DQX1 Gene

Protein Domains for DQX1 Gene

UniProtKB/Swiss-Prot:

DQX1_HUMAN
Domain:
  • Contains 1 helicase ATP-binding domain.:
    • Q8TE96
  • Contains 1 helicase C-terminal domain.:
    • Q8TE96
genes like me logo Genes that share domains with DQX1: view

No data available for Gene Families for DQX1 Gene

Function for DQX1 Gene

Molecular function for DQX1 Gene

UniProtKB/Swiss-Prot CatalyticActivity: ATP + H(2)O = ADP + phosphate

Enzyme Numbers (IUBMB) for DQX1 Gene

Gene Ontology (GO) - Molecular Function for DQX1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004004 ATP-dependent RNA helicase activity IBA --
GO:0004386 helicase activity --
GO:0005524 ATP binding IEA --
GO:0044822 poly(A) RNA binding IBA --
genes like me logo Genes that share ontologies with DQX1: view

Phenotypes for DQX1 Gene

GenomeRNAi human phenotypes for DQX1:
genes like me logo Genes that share phenotypes with DQX1: view

No data available for Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for DQX1 Gene

Localization for DQX1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for DQX1 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for DQX1 Gene COMPARTMENTS Subcellular localization image for DQX1 gene
Compartment Confidence
cytosol 2
nucleus 2
extracellular 1
plasma membrane 1

Gene Ontology (GO) - Cellular Components for DQX1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus --
GO:0005681 spliceosomal complex IBA --
GO:0005737 cytoplasm IBA --
genes like me logo Genes that share ontologies with DQX1: view

Pathways for DQX1 Gene

SuperPathways for DQX1 Gene

No Data Available

Interacting Proteins for DQX1 Gene

Gene Ontology (GO) - Biological Process for DQX1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000398 mRNA splicing, via spliceosome IBA --
GO:0008152 metabolic process --
genes like me logo Genes that share ontologies with DQX1: view

No data available for Pathways by source for DQX1 Gene

Transcripts for DQX1 Gene

Unigene Clusters for DQX1 Gene

DEAQ box RNA-dependent ATPase 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for DQX1 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4a · 4b · 4c ^ 5 ^ 6a · 6b ^ 7a · 7b · 7c ^ 8 ^ 9 ^ 10a · 10b ^ 11 ^ 12
SP1: - - -
SP2: -
SP3: -
SP4:
SP5: -

Relevant External Links for DQX1 Gene

GeneLoc Exon Structure for
DQX1
ECgene alternative splicing isoforms for
DQX1

Expression for DQX1 Gene

mRNA expression in normal human tissues for DQX1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for DQX1 Gene

This gene is overexpressed in Colon - Transverse (17.0), Small Intestine - Terminal Ileum (11.7), and Esophagus - Mucosa (4.7).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for DQX1 Gene

SOURCE GeneReport for Unigene cluster for DQX1 Gene Hs.191705

genes like me logo Genes that share expressions with DQX1: view

Orthologs for DQX1 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for DQX1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia DQX1 36
  • 99.54 (n)
  • 99.58 (a)
DQX1 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia DQX1 36
  • 87.68 (n)
  • 86.33 (a)
DQX1 37
  • 86 (a)
OneToOne
dog
(Canis familiaris)
Mammalia DQX1 36
  • 88.52 (n)
  • 88.01 (a)
DQX1 37
  • 88 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Dqx1 36
  • 84.08 (n)
  • 84.93 (a)
Dqx1 16
Dqx1 37
  • 84 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia DQX1 37
  • 76 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Dqx1 36
  • 84.27 (n)
  • 85.07 (a)
chicken
(Gallus gallus)
Aves DQX1 36
  • 63.95 (n)
  • 62.29 (a)
lizard
(Anolis carolinensis)
Reptilia DQX1 37
  • 57 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii CABZ01087670.1 37
  • 38 (a)
OneToOne
Dr.10422 36
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes PRP43 37
  • 31 (a)
OneToMany
Species with no ortholog for DQX1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for DQX1 Gene

ENSEMBL:
Gene Tree for DQX1 (if available)
TreeFam:
Gene Tree for DQX1 (if available)

Paralogs for DQX1 Gene

Paralogs for DQX1 Gene

Selected SIMAP similar genes for DQX1 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with DQX1: view

Variants for DQX1 Gene

Sequence variations from dbSNP and Humsavar for DQX1 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type MAF
rs1306917 -- 74,521,776(-) aagag(A/G)gggag intron-variant
rs1306918 -- 74,521,766(-) gagag(A/G)gagag intron-variant
rs2286924 -- 74,518,165(+) CACAA(C/G)GGAGT utr-variant-3-prime
rs3815476 -- 74,518,046(+) ATAGT(C/T)GGAGG downstream-variant-500B
rs6546909 -- 74,519,195(+) AGGAG(A/T)AGGTA synonymous-codon, reference

Structural Variations from Database of Genomic Variants (DGV) for DQX1 Gene

Variant ID Type Subtype PubMed ID
dgv1199e1 CNV Complex 17122850
nsv458185 CNV Loss 19166990
nsv515851 CNV Loss 19592680
dgv4166n71 CNV Loss 21882294

Relevant External Links for DQX1 Gene

HapMap Linkage Disequilibrium report
DQX1

Disorders for DQX1 Gene

No disorders were found for DQX1 Gene.

No data available for UniProtKB/Swiss-Prot for DQX1 Gene

Publications for DQX1 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  3. The SH3 domain of postsynaptic density 95 mediates inflammatory pain through phosphatidylinositol-3-kinase recruitment. (PMID: 20467438) Arbuckle M.I. … Grant S.G. (EMBO Rep. 2010) 3
  4. DQX1, an RNA-dependent ATPase homolog with a novel DEAQ box: expression pattern and genomic sequence comparison of the human and mouse genes. (PMID: 11353393) Ji W. … Meisler M.H. (Mamm. Genome 2001) 4
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4

Products for DQX1 Gene

Sources for DQX1 Gene

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