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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

DPY30 Gene

protein-coding   GIFtS: 46
GCID: GC02M032093

dpy-30 homolog (C. elegans)
 Explore 3 diseases affiliated with
DPY30 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for DPY30    

Aliases
for DPY30 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Dpy-30 Homolog (C. Elegans)1 2     Dpy-30L3
HDPY-301 2     Protein Dpy-30 Homolog2
Saf191 2     Dpy-30L3
Dpy-30-Like Protein2 3     

External Ids:    HGNC: 245901   Entrez Gene: 846612   Ensembl: ENSG000001629617   OMIM: 6120325   UniProtKB: Q9C0053   

Export aliases for DPY30 gene to outside databases

Previous GC identifers: GC02M032103 GC02M031993


Summaries
for DPY30 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for DPY30:
DPY30 is a component of a Set1-like multiprotein histone methyltransferase complex (Cho et al., 2007 (PubMed
17500065)).(supplied by OMIM, May 2008)

UniProtKB/Swiss-Prot: DPY30_HUMAN, Q9C005
Function: As part of the MLL1/MLL complex, involved in the methylation of histone H3 at 'Lys-4', particularly
trimethylation. Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation.
May play some role in histone H3 acetylation. In a teratocarcinoma cell, plays a crucial role in retinoic acid-induced
differentiation along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental
loci. May also play an indirect or direct role in endosomal transport




Genomic Views
for DPY30 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000002.11  NC_018913.1  NT_022184.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the DPY30 gene promoter:
         NCX/Ncx   POU3F2 (N-Oct-5a)   POU3F2 (N-Oct-5b)   Cdc5   POU3F2   GATA-1   E2F-1   E2F   FOXO1a   FOXO1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: DPY30 promoter sequence
   Search SABiosciences Chromatin IP Primers for DPY30

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DPY30


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2p22.3   Ensembl cytogenetic band:  2p22.3   HGNC cytogenetic band: 2p22.3

DPY30 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DPY30 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02M032093:  view genomic region     (about GC identifiers)

Start:
 32,092,878 bp from pter      End:
 32,264,881 bp from pter
Size:
 172,004 bases      Orientation:
 minus strand

Proteins
for DPY30 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: DPY30_HUMAN, Q9C005 (See protein sequence)
Recommended Name: Protein dpy-30 homolog  
Size: 99 amino acids; 11250 Da
Subunit: Homodimer. Core component of several methyltransferase-containing complexes including MLL1/MLL, MLL2/3 (also
named ASCOM complex) and MLL4/WBP7. Each complex is at least composed of ASH2L, RBBP5, WDR5, DPY30, one or more
specific histone methyltransferases (MLL, MLL2/ALR, MLL3 and MLL4/WBP7), and the facultative components MEN1, HCFC1,
HCFC2, NCOA6, KDM6A, PAXIP1/PTIP, PAGR1 and alpha- and beta-tubulin (By similarity). Interacts with ASH2L; the
interaction is direct. Interacts with ARFGEF1. Component of the SET1 complex, at least composed of the catalytic
subunit (SETD1A or SETD1B), WDR5, WDR82, RBBP5, ASH2L/ASH2, CXXC1/CFP1, HCFC1 and DPY30
Subcellular location: Nucleus. Golgi apparatus, trans-Golgi network. Note=Associated with chromatin at regions enriched
in histone H3 trimethylated at 'Lys-4. Highly enriched in gene promoter regions and 5' UTRs, but not in downstream
regions of genes or 3' UTRs (By similarity)
1 PDB 3D structure from and Proteopedia for DPY30:
3G36 (3D)    
Secondary accessions: D6W578

Explore the universe of human proteins at neXtProt for DPY30: NX_Q9C005

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9C005

    • DPY30 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_115963.1  
    ENSEMBL proteins: 
     ENSP00000397583   ENSP00000411685   ENSP00000399358   ENSP00000401668   ENSP00000415620  
     ENSP00000345837   ENSP00000295066  

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    Uscn Proteins for DPY30

    Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730NOT nucleolus IDA--
    GO:0005794Golgi apparatus IEA--
    GO:0005802trans-Golgi network IDA19651892
    GO:0035097histone methyltransferase complex IDA17500065


    DPY30 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for DPY30

    Protein Domains /
    Families
    for DPY30 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    DPY30 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR007858 Dpy-30_motif

    Graphical View of Domain Structure for InterPro Entry Q9C005

    ProtoNet protein and cluster: Q9C005

    1 Blocks protein family: IPB007858 Dpy-30

    UniProtKB/Swiss-Prot: DPY30_HUMAN, Q9C005
    Similarity: Belongs to the dpy-30 family


    Function
    for DPY30 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: DPY30_HUMAN, Q9C005
    Function: As part of the MLL1/MLL complex, involved in the methylation of histone H3 at 'Lys-4', particularly
    trimethylation. Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation.
    May play some role in histone H3 acetylation. In a teratocarcinoma cell, plays a crucial role in retinoic acid-induced
    differentiation along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental
    loci. May also play an indirect or direct role in endosomal transport

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat DPY30
    1 QIAGEN miScript miRNA Assays for microRNA that regulate DPY30:
    hsa-miR-139-5p
    SwitchGear 3'UTR luciferase reporter plasmid: DPY30 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DPY30 (see all 4)
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    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for DPY30

    Clone
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    Search LifeMap BioReagents cell lines for DPY30

    In Situ Assay
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    Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI19556245
    GO:0042802identical protein binding IPI19556245
    GO:0042803protein homodimerization activity IPI19556245


    DPY30 for ontologies           About GeneDecksing



    Pathways & Interactions
    for DPY30 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for DPY30

    STRING Interaction Network Preview (showing 5 interactants - click image to see 21)

    5/27 Interacting proteins for DPY30 (Q9C0051, 2, 3 ENSP000002950664) via UniProtKB, MINT, STRING, and/or I2D (see all 27)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ASH2LQ9UBL31, 2, 3, ENSP000003408964EBI-744973,EBI-540797 MINT-66596 I2D: score=6 STRING: ENSP00000340896
    DYDC1Q8WWB32, 3, ENSP000003612764MINT-67906 I2D: score=4 STRING: ENSP00000361276
    DPY30Q9C0051, 2EBI-744973,EBI-744973 MINT-68261
    PRPF3O433952, 3, ENSP000003153794MINT-67744 I2D: score=5 STRING: ENSP00000315379
    UIMC1Q96RL13, ENSP000003664344I2D: score=2 STRING: ENSP00000366434
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006355regulation of transcription, DNA-dependent IEA--
    GO:0016197endosomal transport IMP19651892
    GO:0051568histone H3-K4 methylation IDA19556245


    DPY30 for ontologies           About GeneDecksing



    Drugs & Compounds
    for DPY30 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for DPY30
    Search CenterWatch for drugs/clinical trials and news about DPY30 

    Transcripts
    for DPY30 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for DPY30 gene: 
    NM_032574.2  

    Unigene Cluster for DPY30:

    Dpy-30 homolog (C. elegans)
    Hs.531788  [show with all ESTs]
    Unigene Representative Sequence: BM470539
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000446765(uc002rnz.3 uc010ymv.1) ENST00000452582 ENST00000414013
    ENST00000430665 ENST00000422413 ENST00000342166(uc002roa.1 uc002rob.1)
    ENST00000295066

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat DPY30
    1 QIAGEN miScript miRNA Assays for microRNA that regulate DPY30:
    hsa-miR-139-5p
    SwitchGear 3'UTR luciferase reporter plasmid: DPY30 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DPY30 (see all 4)
    OriGene shRNA RFP: DPY30
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    Clone
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      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DPY30

    Additional cDNA sequence: 

    AF226998.1 BC015970.1 

    15 DOTS entries:

    DT.95300943  DT.446351  DT.100038033  DT.120965250  DT.120965251  DT.99955428  DT.100843334  DT.75130879 
    DT.91677905  DT.95210379  DT.95273290  DT.95273295  DT.99943471  DT.102843127  DT.95363675 

    24/318 AceView cDNA sequences (see all 318):

    AI268698 AA428154 CN484634 AA610033 BM460380 CB140582 CB139619 AA394126 
    BU153205 BX100351 CB852882 BU632294 AF363446 BQ021273 BM978930 CB134761 
    BM772730 BC018733 AI093104 BM909697 AI697932 AA026265 CD366686 CF242900 

    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for DPY30 (see all 6)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e ^ 2 ^ 3a · 3b ^ 4a · 4b · 4c ^ 5a · 5b · 5c · 5d
    SP1:                          -                 -                 -                           
    SP2:                                            -                 -                           
    SP3:                          -                 -     -           -                           
    SP4:                          -                 -                                             
    SP5:                          -                 -     -     -     -                           


    ECgene alternative splicing isoforms for DPY30

    Expression
    for DPY30 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    DPY30 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: ATCATTCCCT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image
    See DPY30 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for DPY30

    SOURCE GeneReport for Unigene cluster: Hs.531788
        SABiosciences Custom PCR Arrays for DPY30
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    In Situ
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    Orthologs
    for DPY30 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for DPY30 gene from 7/23 species (see all 23)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Dpy301 , 5 dpy-30 homolog (C. elegans)1, 5 92.59(n)1
    97.98(a)1    		   17 (45.64 cM)5
    663101  NM_024428.41  NP_077746.31 
     742994745 
    chicken
    (Gallus gallus)    		 Aves DPY301 dpy-30 homolog (C. elegans) 84.18(n)
    89.9(a)    		   421482  NM_001198907.1  NP_001185836.1 
    lizard
    (Anolis carolinensis)    		 Reptilia DPY306
    		 --
    		 84(a)
    		 1 ↔ 1
    		 1(235477978-235481507)
    African clawed frog
    (Xenopus laevis)    		 Amphibia Xl.81752 Xenopus laevis transcribed sequence with moderate similarity to protein refNP_115963.1 (H.sapiens) dpy-30-like protein [Homo sapiens] less 80.52(n)    48051739 
    zebrafish
    (Danio rerio)    		 Actinopterygii dpy301 dpy-30 homolog (C. elegans) 70.57(n)
    78.72(a)    		   436711  NM_001002438.2  NP_001002438.2 
    fruit fly
    (Drosophila melanogaster)    		 Insecta Dpy-30L26
    Dpy-30L16
    		 Dpy-30-like 1
    		 39(a)
    24(a)
    		 many → 1
    many → 1
    		 3L(4046988-4047735)
    2L(10732749-10733307)
    worm
    (Caenorhabditis elegans)    		 Secernentea dpy-306
    		 Dosage compensation protein dpy-30
    		 28(a)
    		 1 ↔ 1
    		 V(12191296-12192192)


    ENSEMBL Gene Tree for DPY30 (if available)
    TreeFam Gene Tree for DPY30 (if available) 

    Paralogs
    for DPY30 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for DPY30 gene
    1 SIMAP similar gene for DPY30 using alignment to 3 protein entries:     DPY30_HUMAN (see all proteins):
    AK7

    DPY30 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for DPY30
    PGOHUM00000239396


    Genomic Variants
    for DPY30 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/285 NCBI SNPs in DPY30 are shown (see all 285)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 2 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs38320761,2
    		C,--32248479(-) TTTTGAATG/-  
                GGAAT     		1 -- ds50011Minor allele frequency- -:0.50NA 2
    rs576406771,2
    		C--32248481(+) TCCCA-/TTCA  
                AAAAC     		1 -- ds50010--------
    rs1470695331,2
    		--32248508(+) CTTGAC/GCATGT 1 -- ds50010--------
    rs1831131371,2
    		--32248622(+) ATGCCG/TGAAAC 1 -- ds50010--------
    rs1384643781,2
    		--32248852(+) GACTGC/TTGTAT 1 -- ds50010--------
    rs1877895901,2
    		--32249066(+) AAATAA/GGTATG 1 -- ut310--------
    rs1910946001,2
    		--32249144(+) TGTCCA/GGAAGG 1 -- ut310--------
    rs1837960381,2
    		--32249161(+) TACATC/GCAAAA 1 -- ut310--------
    rs1496249221,2
    		--32249176(+) GGAATA/GATCAT 1 -- ut310--------
    rs1176485881,2
    		--32249407(+) AAAACT/GCATCT 1 -- int11Minor allele frequency- G:0.01EA 120

    HapMap Linkage Disequilibrium report for DPY30 (32092878 - 32264881 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for DPY30: --

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    Disorders / Diseases
    for DPY30 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    DPY30 for disorders           About GeneDecksing

    OMIM gene information: 612032    OMIM disorders: --

    3 diseases for DPY30:    About MalaCards
    paraplegia    hermaphroditism    leukemia


    Export disorders for DPY30 gene to outside databases

    Publications
    for DPY30 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for DPY30 gene, integrated from 9 sources (see all 30):
    (articles sorted by number of sources associating them with DPY30)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Crystal structure of the C-terminal domain of human DPY-30-like protein: A component of the histone methyltransferase complex. (PubMed id 19481096)1, 2, 9 Wang X.... Rao Z. (2009)
    2. A role of histone H3 lysine 4 methyltransferase components in endosomal trafficking. (PubMed id 19651892)1, 2 Xu Z.... Ma D. (2009)
    3. On the mechanism of multiple lysine methylation by th e human mixed lineage leukemia protein-1 (MLL1) core complex. (PubMed id 19556245)1, 2 Patel A....Cosgrove M.S. (2009)
    4. Molecular regulation of H3K4 trimethylation by Wdr82, a component of human Set1/COMPASS. (PubMed id 18838538)1, 2 Wu M....Shilatifard A. (2008)
    5. PTIP Associates with MLL3- and MLL4-containing Histone H3 Lysine 4 Methyltransferase Complex. (PubMed id 17500065)1, 2 Cho Y.W.... Ge K. (2007)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
    8. Characterization and crystallization of human DPY-30-like protein, an essential component of dosage compensation complex. (PubMed id 16260194)1, 9 Dong X....Rao Z. (2005)
    9. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    10. Structure of the SPRY domain of human Ash2L and its in teractions with RbBP5 and DPY30. (PubMed id 22231628)1 Chen Y....Lei M. (2012)

    External Searches for DPY30 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    Aliases
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    Genome Databases showing DPY30 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 84661 HGNC: 24590 AceView: C2orf4 Ensembl:ENSG00000162961 euGenes: HUgn84661
    ECgene: DPY30 H-InvDB: DPY30

    Other Databases showing DPY30 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing DPY30 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for DPY30 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for DPY30 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for DPY30 gene:
    Search GeneIP for patents involving DPY30

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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