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Aliases for DPY19L4 Gene

Aliases for DPY19L4 Gene

  • Dpy-19-Like 4 (C. Elegans) 2 3
  • Protein Dpy-19 Homolog 4 4
  • Dpy-19-Like Protein 4 4
  • EC 2.4.1.- 4

External Ids for DPY19L4 Gene

Summaries for DPY19L4 Gene

GeneCards Summary for DPY19L4 Gene

DPY19L4 (Dpy-19-Like 4 (C. Elegans)) is a Protein Coding gene. GO annotations related to this gene include transferase activity, transferring glycosyl groups. An important paralog of this gene is DPY19L2.

UniProtKB/Swiss-Prot for DPY19L4 Gene

  • Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for DPY19L4 Gene

Genomics for DPY19L4 Gene

Genomic Location for DPY19L4 Gene

94,719,703 bp from pter
94,793,848 bp from pter
74,146 bases
Plus strand

Genomic View for DPY19L4 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for DPY19L4 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for DPY19L4 Gene

Regulatory Elements for DPY19L4 Gene

Proteins for DPY19L4 Gene

  • Protein details for DPY19L4 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Probable C-mannosyltransferase DPY19L4
    Protein Accession:
    Secondary Accessions:
    • Q6ZW32
    • Q6ZW42
    • Q7Z329

    Protein attributes for DPY19L4 Gene

    723 amino acids
    Molecular mass:
    83756 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAC85664.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for DPY19L4 Gene

Proteomics data for DPY19L4 Gene at MOPED

Post-translational modifications for DPY19L4 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for DPY19L4 Gene

Domains for DPY19L4 Gene

Protein Domains for DPY19L4 Gene


Suggested Antigen Peptide Sequences for DPY19L4 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the dpy-19 family.:
    • Q7Z388
genes like me logo Genes that share domains with DPY19L4: view

No data available for Gene Families for DPY19L4 Gene

Function for DPY19L4 Gene

Molecular function for DPY19L4 Gene

UniProtKB/Swiss-Prot Function: Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins.

Enzyme Numbers (IUBMB) for DPY19L4 Gene

Gene Ontology (GO) - Molecular Function for DPY19L4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000030 mannosyltransferase activity IBA --
GO:0016757 transferase activity, transferring glycosyl groups --
genes like me logo Genes that share ontologies with DPY19L4: view

miRNA for DPY19L4 Gene

miRTarBase miRNAs that target DPY19L4

No data available for Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for DPY19L4 Gene

Localization for DPY19L4 Gene

Subcellular locations from UniProtKB/Swiss-Prot for DPY19L4 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for DPY19L4 Gene COMPARTMENTS Subcellular localization image for DPY19L4 gene
Compartment Confidence
plasma membrane 3
peroxisome 2

Gene Ontology (GO) - Cellular Components for DPY19L4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005637 nuclear inner membrane IBA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with DPY19L4: view

Pathways for DPY19L4 Gene

SuperPathways for DPY19L4 Gene

No Data Available

Interacting Proteins for DPY19L4 Gene

STRING Interaction Network Preview (showing 4 interactants - click image to see details)
Selected Interacting proteins: ENSP00000389630 for DPY19L4 Gene via STRING

Gene Ontology (GO) - Biological Process for DPY19L4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008152 metabolic process --
GO:0018406 protein C-linked glycosylation via 2-alpha-mannosyl-L-tryptophan IBA --
genes like me logo Genes that share ontologies with DPY19L4: view

No data available for Pathways by source for DPY19L4 Gene

Transcripts for DPY19L4 Gene

Unigene Clusters for DPY19L4 Gene

Dpy-19-like 4 (C. elegans):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for DPY19L4 Gene

ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b ^ 7a · 7b · 7c ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20
SP1: - - -
SP2: -
SP3: - - -

Relevant External Links for DPY19L4 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for DPY19L4 Gene

mRNA expression in normal human tissues for DPY19L4 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for DPY19L4 Gene

SOURCE GeneReport for Unigene cluster for DPY19L4 Gene Hs.567828

mRNA Expression by UniProt/SwissProt for DPY19L4 Gene

Tissue specificity: Widely expressed.
genes like me logo Genes that share expressions with DPY19L4: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA differential expression in normal tissues for DPY19L4 Gene

Orthologs for DPY19L4 Gene

This gene was present in the common ancestor of animals.

Orthologs for DPY19L4 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia DPY19L4 35
  • 99.54 (n)
  • 99.02 (a)
DPY19L4 36
  • 98 (a)
(Bos Taurus)
Mammalia DPY19L4 35
  • 93.78 (n)
  • 95.3 (a)
DPY19L4 36
  • 95 (a)
(Canis familiaris)
Mammalia DPY19L4 35
  • 94.71 (n)
  • 96.52 (a)
DPY19L4 36
  • 96 (a)
(Mus musculus)
Mammalia Dpy19l4 35
  • 86.8 (n)
  • 88.64 (a)
Dpy19l4 16
Dpy19l4 36
  • 89 (a)
(Monodelphis domestica)
Mammalia DPY19L4 36
  • 86 (a)
(Ornithorhynchus anatinus)
Mammalia DPY19L4 36
  • 89 (a)
(Rattus norvegicus)
Mammalia Dpy19l4 35
  • 87.21 (n)
  • 88.23 (a)
(Gallus gallus)
Aves DPY19L4 35
  • 79.04 (n)
  • 83.75 (a)
DPY19L4 36
  • 81 (a)
(Anolis carolinensis)
Reptilia DPY19L4 36
  • 75 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia dpy19l4 35
  • 68.75 (n)
  • 69.31 (a)
Str.16649 35
fruit fly
(Drosophila melanogaster)
Insecta CG6659 36
  • 15 (a)
Species with no ortholog for DPY19L4:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for DPY19L4 Gene

Gene Tree for DPY19L4 (if available)
Gene Tree for DPY19L4 (if available)

Paralogs for DPY19L4 Gene

Paralogs for DPY19L4 Gene

Selected SIMAP similar genes for DPY19L4 Gene using alignment to 8 proteins: Pseudogenes for DPY19L4 Gene

genes like me logo Genes that share paralogs with DPY19L4: view

Variants for DPY19L4 Gene

Sequence variations from dbSNP and Humsavar for DPY19L4 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type MAF
rs11025 -- 94,791,522(-) GTGAC(C/T)CACTA utr-variant-3-prime
rs1130289 -- 94,790,695(+) TTCAG(G/T)TTTTT utr-variant-3-prime
rs1130296 -- 94,791,673(+) AGAAC(A/C)CCCTA utr-variant-3-prime
rs3924073 -- 94,759,140(-) CGCTC(G/T)TCACA intron-variant
rs3924074 -- 94,758,945(-) CCAGC(C/T)TGGCC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for DPY19L4 Gene

Variant ID Type Subtype PubMed ID
nsv511392 CNV Loss 21212237
esv2657874 CNV Deletion 23128226
esv2674010 CNV Deletion 23128226
esv271096 CNV Insertion 20981092

Relevant External Links for DPY19L4 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for DPY19L4 Gene

Disorders for DPY19L4 Gene

No disorders were found for DPY19L4 Gene.

No data available for UniProtKB/Swiss-Prot for DPY19L4 Gene

Publications for DPY19L4 Gene

  1. DNA cloning using in vitro site-specific recombination. (PMID: 11076863) Hartley J.L. … Brasch M.A. (Genome Res. 2000) 3
  2. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PMID: 11230166) Wiemann S. … Poustka A. (Genome Res. 2001) 3
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  4. From ORFeome to biology: a functional genomics pipeline. (PMID: 15489336) Wiemann S. … Poustka A. (Genome Res. 2004) 3
  5. The LIFEdb database in 2006. (PMID: 16381901) Mehrle A. … Wiemann S. (Nucleic Acids Res. 2006) 3

Products for DPY19L4 Gene

  • antibodies-online peptides for DPY19L4
  • antibodies-online antibodies for DPY19L4
  • antibodies-online kits for DPY19L4

Sources for DPY19L4 Gene

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