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Aliases for DPY19L3 Gene

Aliases for DPY19L3 Gene

  • Dpy-19-Like 3 (C. Elegans) 2 3
  • Protein Dpy-19 Homolog 3 4
  • Dpy-19-Like Protein 3 4
  • EC 2.4.1.- 4

External Ids for DPY19L3 Gene

Summaries for DPY19L3 Gene

GeneCards Summary for DPY19L3 Gene

DPY19L3 (Dpy-19-Like 3 (C. Elegans)) is a Protein Coding gene. GO annotations related to this gene include transferase activity, transferring glycosyl groups. An important paralog of this gene is DPY19L2.

UniProtKB/Swiss-Prot for DPY19L3 Gene

  • Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for DPY19L3 Gene

Genomics for DPY19L3 Gene

Genomic Location for DPY19L3 Gene

32,405,543 bp from pter
32,485,895 bp from pter
80,353 bases
Plus strand

Genomic View for DPY19L3 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for DPY19L3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for DPY19L3 Gene

Regulatory Elements for DPY19L3 Gene

Proteins for DPY19L3 Gene

  • Protein details for DPY19L3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Probable C-mannosyltransferase DPY19L3
    Protein Accession:
    Secondary Accessions:
    • Q68DC7
    • Q6ZTB7
    • Q6ZTS2

    Protein attributes for DPY19L3 Gene

    716 amino acids
    Molecular mass:
    83197 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAC86508.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for DPY19L3 Gene


neXtProt entry for DPY19L3 Gene

Proteomics data for DPY19L3 Gene at MOPED

Post-translational modifications for DPY19L3 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for DPY19L3 Gene

No data available for DME Specific Peptides for DPY19L3 Gene

Domains for DPY19L3 Gene

Protein Domains for DPY19L3 Gene



  • Belongs to the dpy-19 family.:
    • Q6ZPD9
genes like me logo Genes that share domains with DPY19L3: view

No data available for Gene Families for DPY19L3 Gene

Function for DPY19L3 Gene

Molecular function for DPY19L3 Gene

UniProtKB/Swiss-Prot Function: Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins.

Enzyme Numbers (IUBMB) for DPY19L3 Gene

Gene Ontology (GO) - Molecular Function for DPY19L3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000030 mannosyltransferase activity IBA --
GO:0016757 transferase activity, transferring glycosyl groups --
genes like me logo Genes that share ontologies with DPY19L3: view

Phenotypes for DPY19L3 Gene

genes like me logo Genes that share phenotypes with DPY19L3: view

miRNA for DPY19L3 Gene

miRTarBase miRNAs that target DPY19L3

No data available for Animal Models , Transcription Factor Targeting and HOMER Transcription for DPY19L3 Gene

Localization for DPY19L3 Gene

Subcellular locations from UniProtKB/Swiss-Prot for DPY19L3 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for DPY19L3 Gene COMPARTMENTS Subcellular localization image for DPY19L3 gene
Compartment Confidence
plasma membrane 3
peroxisome 2

Gene Ontology (GO) - Cellular Components for DPY19L3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005637 nuclear inner membrane IBA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with DPY19L3: view

Pathways for DPY19L3 Gene

SuperPathways for DPY19L3 Gene

No Data Available

Interacting Proteins for DPY19L3 Gene

Gene Ontology (GO) - Biological Process for DPY19L3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008152 metabolic process --
GO:0018406 protein C-linked glycosylation via 2-alpha-mannosyl-L-tryptophan IBA --
genes like me logo Genes that share ontologies with DPY19L3: view

No data available for Pathways by source for DPY19L3 Gene

Transcripts for DPY19L3 Gene

Unigene Clusters for DPY19L3 Gene

Dpy-19-like 3 (C. elegans):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for DPY19L3 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b ^ 7 ^ 8 ^ 9a · 9b ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19a · 19b ^ 20 ^
SP1: - - - - -
SP2: - - - -
SP4: -
SP5: - -
SP6: - -
SP7: -

ExUns: 21a · 21b · 21c

Relevant External Links for DPY19L3 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for DPY19L3 Gene

mRNA expression in normal human tissues for DPY19L3 Gene

Integrated Proteomics: protein expression from ProteomicsDB, MOPED, and MaxQB for DPY19L3 Gene

SOURCE GeneReport for Unigene cluster for DPY19L3 Gene Hs.194392

mRNA Expression by UniProt/SwissProt for DPY19L3 Gene

Tissue specificity: Widely expressed.
genes like me logo Genes that share expressions with DPY19L3: view

Orthologs for DPY19L3 Gene

This gene was present in the common ancestor of animals.

Orthologs for DPY19L3 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia DPY19L3 36
  • 99.58 (n)
  • 99.86 (a)
DPY19L3 37
  • 100 (a)
(Bos Taurus)
Mammalia DPY19L3 36
  • 91.34 (n)
  • 92.32 (a)
DPY19L3 37
  • 92 (a)
(Canis familiaris)
Mammalia DPY19L3 36
  • 90.83 (n)
  • 93.3 (a)
DPY19L3 37
  • 90 (a)
(Mus musculus)
Mammalia Dpy19l3 36
  • 84.36 (n)
  • 87.71 (a)
Dpy19l3 16
Dpy19l3 37
  • 88 (a)
(Monodelphis domestica)
Mammalia DPY19L3 37
  • 84 (a)
(Ornithorhynchus anatinus)
Mammalia DPY19L3 37
  • 84 (a)
(Rattus norvegicus)
Mammalia Dpy19l3 36
  • 84.22 (n)
  • 88.27 (a)
(Gallus gallus)
Aves DPY19L3 36
  • 73.62 (n)
  • 75.77 (a)
DPY19L3 37
  • 75 (a)
(Anolis carolinensis)
Reptilia DPY19L3 37
  • 72 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.8176 36
tropical clawed frog
(Silurana tropicalis)
Amphibia dpy19l3 36
  • 67.61 (n)
  • 68.25 (a)
Str.17229 36
(Danio rerio)
Actinopterygii dpy19l3 36
  • 63.43 (n)
  • 63.94 (a)
DPY19L3 37
  • 62 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG6659 37
  • 16 (a)
Species with no ortholog for DPY19L3:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for DPY19L3 Gene

Gene Tree for DPY19L3 (if available)
Gene Tree for DPY19L3 (if available)

Paralogs for DPY19L3 Gene

Paralogs for DPY19L3 Gene

Selected SIMAP similar genes for DPY19L3 Gene using alignment to 6 proteins: Pseudogenes for DPY19L3 Gene

genes like me logo Genes that share paralogs with DPY19L3: view

Variants for DPY19L3 Gene

Sequence variations from dbSNP and Humsavar for DPY19L3 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs375752 -- 32,450,920(+) CAGTA(A/G)TTGTA intron-variant
rs414898 -- 32,447,475(+) acttt(C/G)ggagg intron-variant
rs723935 -- 32,466,530(+) AGCAC(C/G)TCTCC intron-variant
rs738093 -- 32,439,601(+) ATGCA(A/G)AGTGT intron-variant
rs741441 -- 32,408,168(-) CAACA(C/T)ACCCC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for DPY19L3 Gene

Variant ID Type Subtype PubMed ID
nsv510471 CNV Loss 20534489

Relevant External Links for DPY19L3 Gene

HapMap Linkage Disequilibrium report

Disorders for DPY19L3 Gene

Relevant External Links for DPY19L3

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
genes like me logo Genes that share disorders with DPY19L3: view

No data available for UniProtKB/Swiss-Prot for DPY19L3 Gene

Publications for DPY19L3 Gene

  1. Genome-wide association study of bipolar disorder in European American and African American individuals. (PMID: 19488044) Smith E.N. … Kelsoe J.R. (Mol. Psychiatry 2009) 3 49
  2. Global landscape of HIV-human protein complexes. (PMID: 22190034) JAoger S. … Krogan N.J. (Nature 2012) 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  5. Duplication and relocation of the functional DPY19L2 gene within low copy repeats. (PMID: 16526957) Carson A.R. … Scherer S.W. (BMC Genomics 2006) 4

Products for DPY19L3 Gene

Sources for DPY19L3 Gene

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