Free for academic non-profit institutions. Other users need a Commercial license

Aliases for DPY19L2P1 Gene

Aliases for DPY19L2P1 Gene

  • DPY19L2 Pseudogene 1 2 3 5
  • Dpy-19-Like 2 Pseudogene 1 (C. Elegans) 2
  • Dpy-19-Like Protein 2 Pseudogene 1 4
  • Protein Dpy-19 Homolog 2-Like 1 4
  • EC 2.4.1.- 4

External Ids for DPY19L2P1 Gene

Previous GeneCards Identifiers for DPY19L2P1 Gene

  • GC07U901560
  • GC07M035087

Summaries for DPY19L2P1 Gene

GeneCards Summary for DPY19L2P1 Gene

DPY19L2P1 (DPY19L2 Pseudogene 1) is a Pseudogene. GO annotations related to this gene include transferase activity, transferring glycosyl groups.

UniProtKB/Swiss-Prot for DPY19L2P1 Gene

  • Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins.

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for DPY19L2P1 Gene

Genomics for DPY19L2P1 Gene

Regulatory Elements for DPY19L2P1 Gene

Enhancers for DPY19L2P1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH07G035185 0.9 ENCODE 0.7 -0.4 -359 1.1 ZNF76 SIN3A BMI1 RAD21 ZBTB7B GLIS2 SCRT2 EGR2 ZNF263 ZEB2 DPY19L2P1 TBX20
GH07G035228 1 VISTA dbSUPER 0.3 -43.2 -43174 0.9 MTA2 SMARCA4 POLR2A TBX20 DPY19L2P1
GH07G035248 1.3 VISTA ENCODE dbSUPER 0.2 -63.4 -63350 2.0 TBP KLF1 SUZ12 TAF1 MAX E2F1 POLR2A ZNF143 ZNF600 KLF7 TBX20 DPY19L1 DPY19L2P1
GH07G035253 1.1 ENCODE dbSUPER 0.2 -68.0 -67971 1.1 SIN3A ZNF2 ZNF391 ZNF263 ELF4 ZEB2 REST ZNF623 ZFP69B ZNF341 TBX20 DPY19L1 DPY19L2P1
GH07G035214 0.6 VISTA 0.3 -29.1 -29111 0.7 RNF2 SUZ12 CBX2 SIN3A ZBTB8A EZH2 DPY19L2P1 TBX20
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around DPY19L2P1 on UCSC Golden Path with GeneCards custom track

Promoters for DPY19L2P1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000210798 361 400 ZNF263 CTCF RFX1 NRF1 JUN SIN3A ZEB2 BMI1 RAD21 JUND

Genomic Location for DPY19L2P1 Gene

Chromosome:
7
Start:
35,079,989 bp from pter
End:
35,186,162 bp from pter
Size:
106,174 bases
Orientation:
Minus strand

Genomic View for DPY19L2P1 Gene

Genes around DPY19L2P1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
DPY19L2P1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for DPY19L2P1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for DPY19L2P1 Gene

Proteins for DPY19L2P1 Gene

  • Protein details for DPY19L2P1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6NXN4-D19P1_HUMAN
    Recommended name:
    Putative C-mannosyltransferase DPY19L2P1
    Protein Accession:
    Q6NXN4
    Secondary Accessions:
    • B4E2E3

    Protein attributes for DPY19L2P1 Gene

    Size:
    242 amino acids
    Molecular mass:
    28036 Da
    Quaternary structure:
    No Data Available
    Miscellaneous:
    • It has been suggested that DPY19L2P1 is an inactive pseudogene from which DPY19L2 has evolved by duplication. However, expressed transcript sequences derived from the DPY19L2P1 locus are known to exist.

neXtProt entry for DPY19L2P1 Gene

Post-translational modifications for DPY19L2P1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for DPY19L2P1 Gene

Domains & Families for DPY19L2P1 Gene

Protein Domains for DPY19L2P1 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for DPY19L2P1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q6NXN4

UniProtKB/Swiss-Prot:

D19P1_HUMAN :
  • Belongs to the dpy-19 family.
Family:
  • Belongs to the dpy-19 family.
genes like me logo Genes that share domains with DPY19L2P1: view

No data available for Gene Families for DPY19L2P1 Gene

Function for DPY19L2P1 Gene

Molecular function for DPY19L2P1 Gene

UniProtKB/Swiss-Prot Function:
Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins.

Enzyme Numbers (IUBMB) for DPY19L2P1 Gene

Gene Ontology (GO) - Molecular Function for DPY19L2P1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000030 mannosyltransferase activity IBA --
genes like me logo Genes that share ontologies with DPY19L2P1: view

Animal Model Products

No data available for Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for DPY19L2P1 Gene

Localization for DPY19L2P1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for DPY19L2P1 Gene

Membrane; Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for DPY19L2P1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005637 nuclear inner membrane IBA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with DPY19L2P1: view

No data available for Subcellular locations from COMPARTMENTS for DPY19L2P1 Gene

Pathways & Interactions for DPY19L2P1 Gene

SuperPathways for DPY19L2P1 Gene

No Data Available

Interacting Proteins for DPY19L2P1 Gene

Gene Ontology (GO) - Biological Process for DPY19L2P1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007286 spermatid development IBA --
GO:0018406 protein C-linked glycosylation via 2-alpha-mannosyl-L-tryptophan IBA --
genes like me logo Genes that share ontologies with DPY19L2P1: view

No data available for Pathways by source and SIGNOR curated interactions for DPY19L2P1 Gene

Drugs & Compounds for DPY19L2P1 Gene

No Compound Related Data Available

Transcripts for DPY19L2P1 Gene

mRNA/cDNA for DPY19L2P1 Gene

(6) Additional mRNA sequences :
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for DPY19L2P1 Gene

Dpy-19-like 2 pseudogene 1 (C. elegans):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for DPY19L2P1 Gene

No ASD Table

Relevant External Links for DPY19L2P1 Gene

GeneLoc Exon Structure for
DPY19L2P1
ECgene alternative splicing isoforms for
DPY19L2P1

Expression for DPY19L2P1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for DPY19L2P1 Gene

mRNA differential expression in normal tissues according to GTEx for DPY19L2P1 Gene

This gene is overexpressed in Heart - Left Ventricle (x9.0) and Heart - Atrial Appendage (x8.2).

NURSA nuclear receptor signaling pathways regulating expression of DPY19L2P1 Gene:

DPY19L2P1

SOURCE GeneReport for Unigene cluster for DPY19L2P1 Gene:

Hs.594815

mRNA Expression by UniProt/SwissProt for DPY19L2P1 Gene:

Q6NXN4-D19P1_HUMAN
Tissue specificity: Brain, heart, placenta and testis.
genes like me logo Genes that share expression patterns with DPY19L2P1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for DPY19L2P1 Gene

Orthologs for DPY19L2P1 Gene

Evolution for DPY19L2P1 Gene

ENSEMBL:
Gene Tree for DPY19L2P1 (if available)
TreeFam:
Gene Tree for DPY19L2P1 (if available)

No data available for Orthologs for DPY19L2P1 Gene

Paralogs for DPY19L2P1 Gene

(2) SIMAP similar genes for DPY19L2P1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with DPY19L2P1: view

No data available for Paralogs for DPY19L2P1 Gene

Variants for DPY19L2P1 Gene

Sequence variations from dbSNP and Humsavar for DPY19L2P1 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs1000096171 -- 35,137,132(+) GAAAA(A/T)ACTCA intron-variant
rs1000287500 -- 35,098,606(+) TGGCA(C/G)ATATA intron-variant
rs1000295303 -- 35,160,372(+) TTCTC(C/G/T)CTTTG intron-variant
rs1000307945 -- 35,166,647(+) CATGG(A/T)ATTTA intron-variant
rs1000327796 -- 35,081,917(+) TGAAA(G/T)TAAGC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for DPY19L2P1 Gene

Variant ID Type Subtype PubMed ID
dgv6320n100 CNV gain 25217958
esv3612810 CNV loss 21293372
esv3612811 CNV loss 21293372
nsv830953 CNV gain 17160897
nsv951628 CNV deletion 24416366
nsv970460 CNV duplication 23825009
nsv970461 CNV duplication 23825009
nsv970815 CNV duplication 23825009
nsv981450 CNV duplication 23825009

Relevant External Links for DPY19L2P1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
DPY19L2P1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for DPY19L2P1 Gene

Disorders for DPY19L2P1 Gene

Relevant External Links for DPY19L2P1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
DPY19L2P1

No disorders were found for DPY19L2P1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for DPY19L2P1 Gene

Publications for DPY19L2P1 Gene

  1. Protein array based interactome analysis of amyloid-I^ indicates an inhibition of protein translation. (PMID: 21244100) Virok D.P. … FA1lAPp L. (J. Proteome Res. 2011) 3 64
  2. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) OlA!h J. … OvA!di J. (J. Biol. Chem. 2011) 3 64
  3. Duplication and relocation of the functional DPY19L2 gene within low copy repeats. (PMID: 16526957) Carson A.R. … Scherer S.W. (BMC Genomics 2006) 4 64
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4 64
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for DPY19L2P1 Gene

Sources for DPY19L2P1 Gene

Content
Loading form....