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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

DPT Gene

protein-coding   GIFtS: 56
GCID: GC01M168664

Dermatopontin

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
dermatopontin1 2
Tyrosine-Rich Acidic Matrix Protein2 3
TRAMP2 3

External Ids:    HGNC: 30111   Entrez Gene: 18052   Ensembl: ENSG000001431967   OMIM: 1255975   UniProtKB: Q075073   

Export aliases for DPT gene to outside databases

Previous GC identifers: GC01M166300 GC01M164315 GC01M165360 GC01M165852 GC01M165396 GC01M166931 GC01M139910


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for DPT Gene:
Dermatopontin is an extracellular matrix protein with possible functions in cell-matrix interactions and matrix
assembly. The protein is found in various tissues and many of its tyrosine residues are sulphated. Dermatopontin
is postulated to modify the behavior of TGF-beta through interaction with decorin. (provided by RefSeq, Jul 2008)

GeneCards Summary for DPT Gene: 
DPT (dermatopontin) is a protein-coding gene. Diseases associated with DPT include aniseikonia, and cycloplegia.

UniProtKB/Swiss-Prot: DERM_HUMAN, Q07507
Function: Seems to mediate adhesion by cell surface integrin binding. May serve as a communication link between
the dermal fibroblast cell surface and its extracellular matrix environment. Enhances TGFB1 activity. Inhibits
cell proliferation. Accelerates collagen fibril formation, and stabilizes collagen fibrils against
low-temperature dissociation (By similarity)

Gene Wiki entry for DPT (Dermatopontin) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.2  NT_004487.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the DPT gene promoter:
         NF-1   AML1a   Tal-1   FOXL1   Arnt   E47   HNF-1A   FOXJ2 (long isoform)   HNF-1   Zic3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidDPT promoter sequence
   Search SABiosciences Chromatin IP Primers for DPT

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DPT


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q12-q23   Ensembl cytogenetic band:  1q24.2   HGNC cytogenetic band: 1q12-q23

DPT Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DPT gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M168664:  view genomic region     (about GC identifiers)

Start:
168,664,695 bp from pter      End:
168,698,502 bp from pter
Size:
33,808 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: DERM_HUMAN, Q07507 (See protein sequence)
Recommended Name: Dermatopontin precursor  
Size: 201 amino acids; 24005 Da
Subunit: Interacts with TGFB1, DCN and collagen (By similarity)
Subcellular location: Secreted, extracellular space, extracellular matrix (By similarity)
Secondary accessions: A8K981 Q8N4R2 Q9UIX8

Explore the universe of human proteins at neXtProt for DPT: NX_Q07507

Explore proteomics data for DPT at MOPED 

Post-translational modifications:

  • UniProtKB: Sulfated on tyrosine residue(s) (By similarity)
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q07507

  • DPT Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    DPT Protein Expression
    REFSEQ proteins: NP_001928.2  
    ENSEMBL proteins: 
     ENSP00000356791  

    Human Recombinant Protein Products for DPT: 
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    OriGene Protein Over-expression Lysate for DPT
    OriGene MassSpec for DPT 
    OriGene Custom Protein Services for DPT
    GenScript Custom Purified and Recombinant Proteins Services for DPT
    Novus Biologicals DPT Proteins
    Novus Biologicals DPT Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for DPT 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005578proteinaceous extracellular matrix IEA--
    GO:0005615extracellular space IDA--
    GO:0031012colocalizes with extracellular matrix ISS--

    DPT for ontologies           About GeneDecksing



    DPT Antibody Products: 
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    Assay Products for DPT: 
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    Cloud-Clone Corp. ELISAs for DPT 
    Cloud-Clone Corp. CLIAs for DPT


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR026645 Dermatopontin_fam

    Graphical View of Domain Structure for InterPro Entry Q07507

    ProtoNet protein and cluster: Q07507

    UniProtKB/Swiss-Prot: DERM_HUMAN, Q07507
    Similarity: Belongs to the dermatopontin family


    DPT for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: DERM_HUMAN, Q07507
    Function: Seems to mediate adhesion by cell surface integrin binding. May serve as a communication link between
    the dermal fibroblast cell surface and its extracellular matrix environment. Enhances TGFB1 activity. Inhibits
    cell proliferation. Accelerates collagen fibril formation, and stabilizes collagen fibrils against
    low-temperature dissociation (By similarity)
    Induction: Induced by TGFB1, repressed by IL4/interleukin-4

         Genatlas biochemistry entry for DPT:
    dermatopontin,human proteoglycan binding cell adhesion protein,22kDa

    Phenotypes:
         3 MGI mutant phenotypes (inferred from 1 allele(MGI details for Dpt):
     adipose tissue  integument  vision/eye 

    DPT for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Dpttm1Hsh for DPT

       inGenious Targeting Laboratory - Custom generated mouse model solutions for DPT 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for DPT

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for DPT 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for DPT 

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat DPT
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate DPT
    SwitchGear 3'UTR luciferase reporter plasmidDPT 3' UTR sequence
    Inhib. RNA
    Products:
        
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    Clone
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    OriGene ORF clones in mouse, rat for DPT
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    GenScript: all cDNA clones in your preferred vector: DPT (NM_001937)
    Sino Biological Human cDNA Clone for DPT
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DPT


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for DPT About                                                                                                See pathways by source

    SuperPathContained pathways About
    1TGF-beta Signaling Pathway
    TGF-beta Signaling Pathway


    1 Sino Biological Pathway for DPT 
        TGF-beta Signaling Pathway


    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for DPT

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    5/12 Interacting proteins for DPT (Q075072, 3 ENSP000003567914) via UniProtKB, MINT, STRING, and/or I2D (see all 12)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    BAG6P463792, 3MINT-64058 I2D: score=5 
    ENSG00000096155P463792, 3MINT-64058 I2D: score=5 
    ENSG00000227761P463792, 3MINT-64058 I2D: score=5 
    ENSG00000228760P463792, 3MINT-64058 I2D: score=5 
    ENSG00000229524P463792, 3MINT-64058 I2D: score=5 
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007155cell adhesion IEA--
    GO:0008285negative regulation of cell proliferation IEA--
    GO:0030199collagen fibril organization IEA--

    DPT for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for DPT (DERM)

    Search CenterWatch for drugs/clinical trials and news about DPT / DERM

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for DPT gene: 
    NM_001937.4  

    Unigene Cluster for DPT:

    Dermatopontin
    Hs.80552  [show with all ESTs]
    Unigene Representative Sequence: NM_001937
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000367817(uc001gfp.3)
    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat DPT
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate DPT
    SwitchGear 3'UTR luciferase reporter plasmidDPT 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for DPT
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DPT
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    GenScript: all cDNA clones in your preferred vector: DPT (NM_001937)
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                         Customized lentivirus expression plasmids for stable overexpression of DPT 
    Primer
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    OriGene qPCR primer pairs and template standards for DPT
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DPT
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DPT

    Additional mRNA sequence: 

    AF086330.1 AL049455.1 BC033736.1 

    4 DOTS entries:

    DT.446347  DT.121339269  DT.95219687  DT.86846979 

    24/201 AceView cDNA sequences (see all 201):

    CR596260 W02773 CD245457 BI768348 AI870036 AI146848 AL553890 C02335 
    AW016451 AI620191 AI140053 AW015361 BP341714 CA405771 AI686000 BM729207 
    AI621291 BQ019103 AL543317 CR591165 CB049474 C04320 BP344429 BF222276 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    DPT expression in normal human tissues (normalized intensities)      DPT embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTTAGCAATC
    DPT Expression
    About this image


    DPT expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/16 selected tissues (see all 16) fully expand
     
     Cartilage (Muscoskeletal System)    fully expand to see all 17 entries
             Intervertebral Disc Annulus Fibrosus Cells Thoracic Intervertebral Disc
             Thoracic Intervertebral Disc
             HyStem+TGFbeta3+GDF5-induced SK11 cells
     
     Bone (Muscoskeletal System)    fully expand to see all 12 entries
             Osteochondro Mesenchymal Cells Sacral Vertebrae
             Zeugopod Epiphyseal End
             HyStem+TGFbeta3+GDF5-induced SK11 cells
     
     Fibroblast
             X-gene Foreskin Fibroblasts   
     
     Skeletal Muscle (Muscoskeletal System)    fully expand to see all 2 entries
             pectoral girdle and thoracic body wall/skeletal muscle   
     
     Dermis (Uncategorized)    fully expand to see all 2 entries
             BH2 Dermal Fibroblasts   

    See DPT Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for DPT

    SOURCE GeneReport for Unigene cluster: Hs.80552

    UniProtKB/Swiss-Prot: DERM_HUMAN, Q07507
    Tissue specificity: Expressed in fibroblasts, heart, skeletal muscle, brain and pancreas. Expressed at an
    intermediate level in lung and kidney, and at a low level in liver and placenta. Expressed at a lower level in
    fibroblasts from hypertrophic scar lesional skin and in fibroblasts from patients with systemic sclerosis than in
    normal skin fibroblasts

        SABiosciences Custom PCR Arrays for DPT
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DPT

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for DPT gene from 4/10 species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Dpt1 , 5 dermatopontin1, 5 88.06(n)1
    92.04(a)1
      1 (72.12 cM)5
    564291  NM_019759.21  NP_062733.11 
     1647967325 
    chicken
    (Gallus gallus)
    Aves DPT1 dermatopontin 77.89(n)
    82.32(a)
      768904  XM_001231675.2  XP_001231676.2 
    lizard
    (Anolis carolinensis)
    Reptilia DPT6
    Uncharacterized protein
    82(a)
    1 ↔ 1
    3(175336625-175355099)
    zebrafish
    (Danio rerio)
    Actinopterygii si:dkey-98p3.21 si:dkey-98p3.2 66.47(n)
    64.16(a)
      555282  NM_001030085.2  NP_001025256.2 


    ENSEMBL Gene Tree for DPT (if available)
    TreeFam Gene Tree for DPT (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/881 SNPs in DPT are shown (see all 881)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs674398711,2
    C--139931888(-) GAACT-/TAAAG 
            
    TAAAA
    1 -- int12Minor allele frequency- TAAAG:0.25NA 4
    rs1464208041,2
    --168664206(+) ATACCA/CTCACC 1 -- int10--------
    rs1895156291,2
    --168664219(+) TGGCTA/GAGAGT 1 -- int10--------
    rs1397920371,2
    --168664246(+) TAGAGA/GGGGTG 1 -- int10--------
    rs6814451,2
    C,F,O,A,H--168664259(+) TGGCAG/AGGTAC 1 -- int119Minor allele frequency- A:0.34NA EA NS WA CSA 970
    rs799145351,2
    C--168664265(+) GGTACG/ACGATC 1 -- int13Minor allele frequency- A:0.05NA EA 242
    rs1811257041,2
    --168664267(+) TACGCA/GATCCC 1 -- int10--------
    rs667015641,2
    C--168664345(+) AAAAA-/AGGCAA 1 -- int10--------
    rs1432728851,2
    C--168664392(+) GGGACA/TTCCTG 1 -- int10--------
    rs6823671,2
    C,F,O,A,H--168664450(+) GCTGAG/AAAAAG 1 -- int129Minor allele frequency- A:0.45NA EA NS WA CSA 2737

    HapMap Linkage Disequilibrium report for DPT (168664695 - 168698502 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for DPT:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv831847CNV Gain17160897
    nsv831836CNV Gain+Loss17160897

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing DPT
    DNA2.0 Custom Variant and Variant Library Synthesis for DPT

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 125597    OMIM disorders: --

    20/33 diseases for DPT (see all 33):    About MalaCards
    aniseikonia    cycloplegia    tungiasis    anisometropia
    hypertrophic scars    varicose veins    amblyopia    poliomyelitis
    smallpox    chickenpox    mumps    astigmatism
    japanese encephalitis    hyperopia    rubella    leiomyoma
    keratoconus    keloids    diphtheria    tetanus

    16 diseases from the University of Copenhagen DISEASES database for DPT:
    Pertussis     Diphtheria     Measles     Tetanus
    Poliomyelitis     Astigmatism     Anisometropia     Myopia
    Cycloplegia     Hyperopia     Mumps     Aniseikonia
    Rubella     Amblyopia     Japanese encephalitis     Hepatitis B

    DPT for disorders           About GeneDecksing

    4 Novoseek inferred disease relationships for DPT gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    leiomyoma 44.4 5 15139000 (4)
    infarct 11.4 3 12395208 (2), 16987749 (1)
    myocardial infarction 3.52 1 16987749 (1)
    tumors 0 2 16899568 (1)

    Genetic Association Database (GAD): DPT
    Human Genome Epidemiology (HuGE) Navigator: DPT (6 documents)

    Export disorders for DPT gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for DPT gene, integrated from 9 sources (see all 31):
    (articles sorted by number of sources associating them with DPT)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Complementary DNA sequence and chromosomal mapping of a human proteoglycan-binding cell-adhesion protein (dermatopontin). (PubMed id 8104875)1, 2, 3, 9 Superti-Furga A.... Gitzelmann R. (1993)
    2. Dermatopontin expression is decreased in hypertrophic scar and systemic sclerosis skin fibroblasts and is regulated by transforming growth factor-beta1, interleukin-4, and matrix collagen. (PubMed id 10233760)1, 2, 9 Kuroda K.... Shinkai H. (1999)
    3. Follow-up of a major linkage peak on chromosome 1 rev eals suggestive QTLs associated with essential hypertension: GenNet study. (PubMed id 19536175)1, 4 Ehret G.B....Chakravarti A. (2009)
    4. Pre-B-cell leukemia homeobox 1 (PBX1) shows functional and possible genetic association with bone mineral density variation. (PubMed id 19064610)1, 4 Cheung C.L....Kung A.W. (2009)
    5. Genetic correlates of longevity and selected age-related phenotypes: a genome-wide association study in the Framingham Study. (PubMed id 17903295)1, 4 Lunetta K.L....Murabito J.M. (2007)
    6. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    8. Dermatopontin interacts with transforming growth factor beta and enhances its biological activity. (PubMed id 9895299)1, 9 Okamoto O.... Sato Y. (1999)
    9. Dermatopontin is expressed in human liver and is down regulated in hepatocellular carcinoma. (PubMed id 19916908)1, 9 Li X....Zhang C. (2009)
    10. Tyrosine-rich acidic matrix protein (TRAMP) is a tyrosine-sulphated and widely distributed protein of the extracellular matrix. (PubMed id 8082810)1, 9 Forbes E.G....Hulmes D.J. (1994)

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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 1805 HGNC: 3011 AceView: DPT Ensembl:ENSG00000143196 euGenes: HUgn1805
    ECgene: DPT H-InvDB: DPT

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
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    About This Section
    NameDescription
    PharmGKB entry for DPT Pharmacogenomics, SNPs, Pathways

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