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DPRX Gene

protein-coding   GIFtS: 36
GCID: GC19P054136

Divergent-Paired Related Homeobox

  Search for DPRX
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Divergent-Paired Related Homeobox1 2
Divergent Paired-Related Homeobox2

External Ids:    HGNC: 321661   Entrez Gene: 5038342   Ensembl: ENSG000002045957   OMIM: 6111655   UniProtKB: A6NFQ73   

Export aliases for DPRX gene to outside databases

Previous GC identifers: GC19U900486 GC19P058828


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for DPRX Gene:
Homeobox genes encode DNA-binding proteins, many of which are thought to be involved in early embryonic
development. Homeobox genes encode a DNA-binding domain of 60 to 63 amino acids referred to as the homeodomain.
This gene is a member of the DPRX homeobox gene family. Evidence of mRNA expression has not yet been found for
this gene. Multiple, related processed pseudogenes have been found which are thought to reflect expression of
this gene in the germ line or embryonic cells. (provided by RefSeq, Jul 2008)

GeneCards Summary for DPRX Gene:
DPRX (divergent-paired related homeobox) is a protein-coding gene. GO annotations related to this gene include sequence-specific DNA binding and sequence-specific DNA binding transcription factor activity.

UniProtKB/Swiss-Prot: DPRX_HUMAN, A6NFQ7
Function: Putative transcription factor (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000019.10  NC_018930.2  NT_011109.17  
Regulatory elements:
   Regulatory transcription factor binding sites in the DPRX gene promoter:
         E4BP4   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidDPRX promoter sequence
   Search Chromatin IP Primers for DPRX

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat DPRX


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.42   Ensembl cytogenetic band:  19q13.42   HGNC cytogenetic band: 19q13.42

DPRX Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DPRX gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19P054136:  view genomic region     (about GC identifiers)

Start:
54,135,310 bp from pter      End:
54,140,263 bp from pter
Size:
4,954 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: DPRX_HUMAN, A6NFQ7 (See protein sequence)
Recommended Name: Divergent paired-related homeobox  
Size: 191 amino acids; 21648 Da

Explore the universe of human proteins at neXtProt for DPRX: NX_A6NFQ7

Explore proteomics data for DPRX at MOPED


See DPRX Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_001012746.1  
ENSEMBL proteins: 
 ENSP00000365838  

DPRX Human Recombinant Protein Products:

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Cloud-Clone Corp. ELISAs for DPRX
Cloud-Clone Corp. CLIAs for DPRX


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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HGNC Gene Families:
PRD: Homeoboxes / PRD class

3 InterPro protein domains:
 IPR017970 Homeobox_CS
 IPR001356 Homeobox_dom
 IPR009057 Homeodomain-like

Graphical View of Domain Structure for InterPro Entry A6NFQ7

ProtoNet protein and cluster: A6NFQ7

UniProtKB/Swiss-Prot: DPRX_HUMAN, A6NFQ7
Similarity: Belongs to the paired homeobox family
Similarity: Contains 1 homeobox DNA-binding domain


DPRX for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

     UniProtKB/Swiss-Prot Summary: DPRX_HUMAN, A6NFQ7
Function: Putative transcription factor (By similarity)

     Gene Ontology (GO): 3 molecular function terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0003677DNA binding ----
GO:0003700sequence-specific DNA binding transcription factor activity IEA--
GO:0043565sequence-specific DNA binding IEA--
     
DPRX for ontologies           About GeneDecksing


Animal Models:
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   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for DPRX
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for DPRX

miRNA
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Browse SwitchGear 3'UTR luciferase reporter plasmids
Inhib. RNA
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Predesigned siRNA for gene silencing in human, mouse, rat DPRX

Gene Editing
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Browse Sino Biological Human cDNA Clones
DNA2.0 Custom Codon Optimized Gene Synthesis Service for DPRX
Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat DPRX

Cell Line
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GenScript Custom overexpressing Cell Line Services for DPRX
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In Situ Assay
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DPRX


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot
DPRX_HUMAN, A6NFQ7: Nucleus (By similarity)
Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
nucleus3
golgi apparatus1

Gene Ontology (GO): 1 cellular component term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005634nucleus IEA--

DPRX for ontologies           About GeneDecksing


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for DPRX
Interactions:

    Search GeneGlobe Interaction Network for DPRX

STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

2 Interacting proteins for DPRX (A6NFQ73 ENSP000003658384) via UniProtKB, MINT, STRING, and/or I2D
InteractantInteraction Details
GeneCardExternal ID(s)
ATG5Q9H1Y03I2D: score=1 
CHEK2ENSP000003720234STRING: ENSP00000372023
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Gene Ontology (GO): 2 biological process terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0006351transcription, DNA-templated IEA--
GO:0006355regulation of transcription, DNA-templated ----

DPRX for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for DPRX



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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REFSEQ mRNAs for DPRX gene: 
NM_001012728.1  

Unigene Cluster for DPRX:

Divergent-paired related homeobox
Hs.579941
Unigene Representative Sequence: NM_001012728
1 Ensembl transcript including schematic representation, and UCSC links where relevant:
ENST00000376650(uc002qcf.1)
miRNA
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Search for qRT-PCR Assays for microRNAs that regulate DPRX
Browse SwitchGear 3'UTR luciferase reporter plasmids
Inhib. RNA
Products:
     
OriGene RNAi products in human, mouse, rat for DPRX
Predesigned siRNA for gene silencing in human, mouse, rat DPRX
Clone
Products:
     
OriGene clones in human, mouse for DPRX (see all 5)
OriGene ORF clones in mouse, rat for DPRX
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript Custom all cDNA clones Services for DPRX
DNA2.0 Custom Codon Optimized Gene Synthesis Service for DPRX
Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat DPRX
Primer
Products:
    
OriGene qSTAR qPCR primer pairs in human, mouse for DPRX
Pre-validated RT2 qPCR Primer Assay in human, mouse / rat DPRX
  QuantiTect SYBR Green Assays in human, mouse, rat DPRX
  QuantiFast Probe-based Assays in human, mouse, rat DPRX

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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DPRX expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: TTCACTAAGA
DPRX Expression
About this image


DPRX expression in embryonic tissues and stem cells    About this table
Data from LifeMap, the Embryonic Development and Stem Cells Database
 selected tissues (see all 3) fully expand
 
 Neurons
         Mature Rod Cells Outer Nuclear Layer
 
 Inner Cell Mass (Early Embryonic Tissues)
         Inner Cell Mass Cells Inner Cell Mass
 
 Eye (Sensory Organs)
         Mature Rod Cells Outer Nuclear Layer
DPRX Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

DPRX Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.579941
    Custom PCR Arrays for DPRX
Primer
Products:
OriGene qSTAR qPCR primer pairs in human, mouse for DPRX
Pre-validated RT2 qPCR Primer Assay in human, mouse / rat DPRX
QuantiTect SYBR Green Assays in human, mouse, rat DPRX
QuantiFast Probe-based Assays in human, mouse, rat DPRX
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DPRX

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of human and mouse.

Orthologs for DPRX gene from Selected species (see all 2)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Crxos15 Crx opposite strand transcript 1   --   7 (8.60 cM) 15882617 


ENSEMBL Gene Tree for DPRX (if available)
TreeFam Gene Tree for DPRX (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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Paralogs for DPRX gene
2 SIMAP similar genes for DPRX using alignment to 1 protein entry:     DPRX_HUMAN:
POU6F1    HOXB1

DPRX for paralogs           About GeneDecksing


Selected Pseudogenes.org Pseudogenes for DPRX (see all 7)
PGOHUM00000248130 PGOHUM00000237352 PGOHUM00000239172 PGOHUM00000240455 PGOHUM00000243162


(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for DPRX (see all 201)    About this table    
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 19 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs1413824791,2
--54133445(+) CTGGGC/TGACAG 1 -- us2k10--------
rs1503780661,2
--54133446(+) TGGGCG/TACAGA 1 -- us2k10--------
rs288206441,2
--54133457(+) GTGAGA/GCTCCA 1 -- us2k10--------
rs2007931321,2
--54133472(+) AAAAA-/CAAAAA 1 -- us2k10--------
rs121509621,2
C--54133473(+) aaaaaC/Aaaaaa 1 -- us2k1 trp31Minor allele frequency- A:0.50NA 2
rs287182411,2
--54133486(+) AAACTC/TTCATG 1 -- us2k10--------
rs605525411,2
F--54133519(+) TGTGAA/TTTGCC 1 -- us2k11Minor allele frequency- T:0.05WA 118
rs1997293151,2
C--54133997(+) AATGGA/CAAGAA 1 -- us2k10--------
rs1465063681,2
C--54134005(+) AAAAA-/AA    
   ACC
/C
CTGCC
1 -- us2k10--------
rs1998808531,2
C--54134005(-) GGCAGG/TTTTTC 1 -- us2k10--------
rs1911474361,2
--54134164(+) GGTGCA/GATCTC 1 -- us2k10--------
rs1471627691,2
C--54134433(+) CCAGCG/TACTGG 1 -- us2k10--------
rs104172101,2
C--54134440(+) ctgggA/Gaggct 1 -- us2k10--------
rs1432083821,2
--54134476(+) AGAGGC/TGGAGG 1 -- us2k10--------
rs129749641,2
C--54134499(+) gagatT/Cgtgcc 1 -- us2k13Minor allele frequency- C:0.17NA CSA 6
rs1153794061,2
F--54134632(+) ATATTA/TGCCAC 1 -- us2k11Minor allele frequency- T:0.01WA 118
rs104182181,2
C,F,H--54134663(+) TGAAAG/TCCCCT 1 -- us2k111Minor allele frequency- T:0.05NS EA WA 1644
rs1821697011,2
--54134763(+) AAATCA/GTCAGA 1 -- us2k10--------
rs1485624431,2
--54134807(+) CAGGAA/GTTCAA 1 -- us2k10--------
rs1173826821,2
F--54134842(+) AACTCC/TGTCTC 1 -- us2k11Minor allele frequency- T:0.01NA 120
rs1429512991,2
C--54134906(+) CTACTC/TGGGAG 1 -- us2k10--------
rs48019951,2
C,A--54134979(+) ATTGCA/GCTCCA 1 -- us2k18Minor allele frequency- G:0.07NA CSA 133
rs1868571501,2
--54135052(+) TTCTGC/TTCAGG 1 -- us2k10--------
rs1916401841,2
--54135069(+) GGAGTA/GGGCCA 1 -- us2k10--------
rs1511221561,2
C--54135141(+) GAGTCA/GTTGGT 1 -- us2k10--------
rs1830088641,2
--54135216(+) CGAGGA/GATCAT 1 -- us2k10--------
rs1884498681,2
C--54135276(+) TGGCTA/GTGGAG 1 -- us2k10--------
rs1928840681,2
C--54135321(+) TTCTTA/GTCCCT 1 -- ut510--------
rs1854105861,2
C--54135342(+) CCAGGC/TGCACA 1 -- ut511Minor allele frequency- T:0.00EU 1249
rs2011920051,2
--54135346(+) GCGCAC/TATCTG 1 -- ut510--------
rs1488962321,2
C,F--54135382(+) ATCTTC/TGTAAA 2 R C mis11Minor allele frequency- T:0.00NA 4552
rs3752508861,2
C--54135453(+) CGGCGC/GGAAAA 1 -- int10--------
rs770577971,2
C--54135467(+) AGAGGG/TACCAG 1 -- int10--------
rs752356391,2
C--54135468(+) GAGGGA/CCCAGG 1 -- int10--------
rs1436253011,2
C--54135474(+) CCAGGC/TGGCCG 1 -- int10--------
rs1892305001,2
--54135479(+) CGGCCA/GAAGCT 1 -- int10--------
rs116693541,2
C,F,H--54135534(+) TCATCG/ATTTTT 1 -- int117Minor allele frequency- A:0.15NS EA NA 1950
rs356352031,2
C,F--54135570(+) TTTGTC/TTTTTG 1 -- int19Minor allele frequency- T:0.38NA WA CSA EA 370
rs1118067491,2
F--54135648(+) CTCCCG/AGGTTC 1 -- int11Minor allele frequency- A:0.50CSA 2
rs1925814511,2
--54135659(+) AAGCAA/GTTCTC 1 -- int10--------
rs104255391,2
C,H--54135693(+) GGGATT/GACAGG 1 -- int110Minor allele frequency- G:0.00NA WA CSA 19
rs563468121,2
C--54135734(+) TTTTT-/T/TT  
        
GTATT
1 -- int11NA 2
rs1835027321,2
C--54135754(+) AGCCGC/GGGGTT 1 -- int10--------
rs1881754181,2
--54135817(+) CTCAGC/TCTCCC 1 -- int10--------
rs1447654571,2
--54135840(+) TGACAG/TGCGTG 1 -- int10--------
rs110842681,2
C,F,H--54135985(+) GAGCCT/ACGGTG 1 -- int16Minor allele frequency- A:0.42NA CSA EA 249
rs1810855121,2
--54136100(+) ACCCCA/GATGCT 1 -- int10--------
rs124615511,2
C,F,H--54136167(+) ATATAG/AGCTTA 1 -- int17Minor allele frequency- A:0.04NS EA WA NA 538
rs81021631,2
C,F,A--54136283(+) ggtggC/Ttcatg 1 -- int19Minor allele frequency- T:0.42WA NA CSA EA 369
rs789700781,2
C--54136385(+) TCTCT-/CMAAAA 1 -- int10--------
rs672357391,2
C--54136386(-) TTTTT-/GTAGAG 1 -- int11Minor allele frequency- G:0.00NA 2
rs81032311,2
C,A--54136414(+) gcatgG/Tcagtg 1 -- int19Minor allele frequency- T:0.16NA WA CSA EA 368
rs1863237591,2
--54136462(+) GGATCA/GCTTGA 1 -- int10--------
rs1455429321,2
--54136563(+) ACATCC/TGTGAC 1 -- int10--------
rs1143330701,2
F--54136566(+) TCCGTG/AACAGC 1 -- int11Minor allele frequency- A:0.03WA 118
rs1899922031,2
--54136576(+) CAGTGA/TTGTTA 1 -- int10--------
rs1816481891,2
--54136608(+) TATATG/TCCTAA 1 -- int10--------
rs1488768441,2
--54136736(+) ACAAGC/TGATCC 1 -- int10--------
rs1870547151,2
C--54136880(+) TGCCTC/TAGCCT 1 -- int10--------
rs1435867091,2
C--54136966(+) ACCATA/GTTAGC 1 -- int10--------
rs1480702531,2
--54136976(+) CCAGAA/GTGGTC 1 -- int10--------
rs116714501,2
C,A,H--54137005(+) gatccA/Gcccgc 1 -- int14Minor allele frequency- G:0.00NA 8
rs1908999201,2
--54137009(+) CGCCCA/GCCTTG 1 -- int10--------
rs285042311,2
--54137041(+) ACAGGC/TATGAG 1 -- int10--------
rs284213261,2
--54137042(+) CAGGCA/GTGAGC 1 -- int10--------
rs1507460701,2
C--54137051(+) GCCACG/TGTGCC 1 -- int10--------
rs1834080901,2
--54137053(+) CACTGG/TGCCCG 1 -- int10--------
rs1393445941,2
--54137223(+) AGGATA/GGAGGA 1 -- int10--------
rs129852961,2
C,F,H--54137359(+) AGGCAC/TGACCC 1 -- int17Minor allele frequency- T:0.19NS EA NA 642
rs1496184891,2
--54137423(+) CTCACA/GCATGT 1 -- int10--------
rs1118777931,2
C,F--54137541(+) TTATCC/TGGGCA 1 -- int12Minor allele frequency- T:0.50CSA 4
rs1401957021,2
--54137553(+) GGTGGC/TGTGCG 1 -- int10--------
rs1435850191,2
C--54137588(+) GCTGAA/GGCAGG 1 -- int10--------
rs1175104401,2
F--54137691(+) CATCAC/TGTTGT 1 -- int11Minor allele frequency- T:0.01NA 120
rs133462181,2
C,F,A--54137721(+) GAAAGC/TTCAGG 1 -- int15Minor allele frequency- T:0.06WA CSA NA 244
rs2014390141,2
C--54137743(+) GGAGTC/TGTTAG 1 -- int10--------
rs1509272641,2
--54137883(+) CAAACC/GCCAGC 2 P A mis10--------
rs1467985101,2
--54138069(+) ACTCAA/CGTCCC 1 -- int10--------
rs1395231531,2
--54138070(+) CTCACA/GTCCCC 1 -- int10--------
rs1851206761,2
--54138114(+) GGGAAA/CATTTT 1 -- int10--------
rs1428445331,2
C--54138158(+) CTTTGG/TGGGCC 1 -- int10--------
rs752816831,2
F--54138237(+) CAAGAG/AGCCCA 1 -- int11Minor allele frequency- A:0.01WA 118
rs1898305961,2
--54138281(+) GAGCAC/TGGTGG 1 -- int10--------
rs1830096791,2
--54138319(+) CCTCCC/TGGGCT 1 -- int10--------
rs1510683711,2
C--54138346(+) CTCAGC/GACCCC 1 -- int10--------
rs1402832371,2
--54138359(+) GTAGCA/TGGGAC 1 -- int10--------
rs1503582141,2
--54138399(+) CCAAAA/GTGTTG 1 -- int10--------
rs1879177351,2
--54138417(+) AAGCAG/TGAGCC 1 -- int10--------
rs748375131,2
C,F--54138452(+) GATGGG/AGTTTC 1 -- int13Minor allele frequency- A:0.06WA NA EA 358
rs116727551,2
C,F,H--54138543(+) ataggC/Tataag 1 -- int110Minor allele frequency- T:0.36NS EA NA WA 784
rs72569331,2
C,F,A,H--54138544(+) taggcG/Ataagc 1 -- int112Minor allele frequency- A:0.44NS EA NA CSA WA 788
rs735909441,2
C,F--54138614(+) TTGTTG/TTAAGA 1 -- int11Minor allele frequency- T:0.50WA 2
rs730536971,2
C--54138642(+) CCACAC/TTGGAG 1 -- int10--------
rs116727921,2
C,F,A,H--54138658(+) tggcaC/Tgatca 1 -- int19Minor allele frequency- T:0.34NA WA EA 370
rs1929622531,2
--54138740(+) CAGGTA/GTGTGG 1 -- int10--------
rs1833131841,2
--54138755(+) ACAGCC/TTCCCG 1 -- int10--------
rs1874276111,2
--54138898(+) CCAGAC/GTCCTG 1 -- int10--------
rs1923183451,2
--54138994(+) CACAAA/TATAGT 1 -- int10--------
rs1412113171,2
C--54139076(+) AAGAC-/AGGGGGT 1 -- int10--------
rs104013571,2
C,F,A,H--54139159(+) CTCTCC/TTATCC 1 -- int114Minor allele frequency- T:0.35NS EA NA WA 786
rs1461795731,2
--54139189(+) CCCCTG/TTCTCA 1 -- int10--------
rs744945191,2
C,F--54139264(+) AAGAGG/TATGTA 1 -- int11Minor allele frequency- T:0.03NA 120
rs104032951,2
C,F,A--54139342(+) TTGggT/Ctgggt 1 -- int13Minor allele frequency- C:0.07WA CSA 122
rs1386029451,2
--54139431(+) CCTGGC/TCAATA 1 -- int10--------
rs777647321,2
C--54139580(+) GTGCCA/CCTGAA 1 -- int10--------
rs1480165001,2
--54139599(+) TGGGCA/GACAAG 1 -- int10--------
rs1847044061,2
--54139628(+) AATAAA/CATAAA 1 -- int10--------
rs354363471,2
--54139640(+) TAAAAT/AAAAAA 1 -- int11Minor allele frequency- A:0.50NA 2
rs2020471211,2
--54139641(+) AAAAT-/AAAAATA 1 -- int10--------
rs350864691,2
--54139642(+) AAATAT/AAAATA 1 -- int11Minor allele frequency- A:0.50NA 2
rs1845926831,2
--54139663(+) TAAATA/GTTAGG 1 -- int10--------
rs2000777591,2
C--54139692(+) AAAGG-/AAAAAA 1 -- int10--------
rs595703051,2
C--54139700(+) AAAAA-/A/A   
   GAAAA
GAAAA
2 -- int1 cds12NA 4

HapMap Linkage Disequilibrium report for DPRX (54135310 - 54140263 bp)

Structural Variations
     Database of Genomic Variants (DGV) 3 variations for DPRX:    About this table    
Variant IDTypeSubtypePubMed ID
esv2718812CNV Deletion23290073
nsv515586CNV Loss19592680
nsv912385CNV Gain21882294

Site Specific Mutation Identification with PCR Assays
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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 611165    OMIM disorders: --


DPRX for disorders           About GeneDecksing


Export disorders for DPRX gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for DPRX gene integrated from 10 sources:
(articles sorted by number of sources associating them with DPRX)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Annotation, nomenclature and evolution of four novel homeobox genes expressed in the human germ line. (PubMed id 17005330)1, 2 Booth H.A. and Holland P.W.H. (Gene 2007)
  2. The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)2 Grimwood J.... Lucas S.M. (Nature 2004)

(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 503834 HGNC: 32166 Ensembl:ENSG00000204595 euGenes: HUgn503834 ECgene: DPRX
H-InvDB: DPRX

(According to HUGE)
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  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for DPRX Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for DPRX gene:
Search GeneIP for patents involving DPRX

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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