Aliases for DPP9 Gene
External Ids for DPP9 Gene
Previous GeneCards Identifiers for DPP9 Gene
This gene encodes a protein that is a member of the S9B family in clan SC of the serine proteases. The protein has been shown to have post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. Although the activity of this protein is similar to that of dipeptidyl peptidase 4 (DPP4), it does not appear to be membrane bound. In general, dipeptidyl peptidases appear to be involved in the regulation of the activity of their substrates and have been linked to a variety of diseases including type 2 diabetes, obesity and cancer. Several transcript variants of this gene have been described but not fully characterized. [provided by RefSeq, Jul 2008]
GeneCards Summary for DPP9 Gene
DPP9 (Dipeptidyl Peptidase 9) is a Protein Coding gene. Diseases associated with DPP9 include Pulmonary Fibrosis, Idiopathic. Among its related pathways are Lung fibrosis. GO annotations related to this gene include identical protein binding and serine-type peptidase activity. An important paralog of this gene is DPP8.
UniProtKB/Swiss-Prot for DPP9 Gene
Dipeptidyl peptidase that cleaves off N-terminal dipeptides from proteins having a Pro or Ala residue at position 2.