Aliases for DPH7 Gene
External Ids for DPH7 Gene
Previous HGNC Symbols for DPH7 Gene
Previous GeneCards Identifiers for DPH7 Gene
WDR85 is a WD repeat-containing protein that plays a role in the first step of diphthamide biosynthesis (Carette et al., 2009 [PubMed 19965467]).[supplied by OMIM, Feb 2010]
GeneCards Summary for DPH7 Gene
DPH7 (Diphthamide Biosynthesis 7) is a Protein Coding gene.
UniProtKB/Swiss-Prot for DPH7 Gene
Catalyzes the demethylation of diphthine methyl ester to form diphthine, an intermediate diphthamide biosynthesis, a post-translational modification of histidine which occurs in translation elongation factor 2 (EEF2) which can be ADP-ribosylated by diphtheria toxin and by Pseudomonas exotoxin A (Eta).