Aliases for DPH6 Gene
External Ids for DPH6 Gene
Previous HGNC Symbols for DPH6 Gene
Previous GeneCards Identifiers for DPH6 Gene
GeneCards Summary for DPH6 Gene
DPH6 (Diphthamine Biosynthesis 6) is a Protein Coding gene. Diseases associated with DPH6 include Spastic Paraplegia 11, Autosomal Recessive. Among its related pathways are Gamma carboxylation, hypusine formation and arylsulfatase activation and Metabolism of proteins. GO annotations related to this gene include diphthine-ammonia ligase activity.
UniProtKB/Swiss-Prot for DPH6 Gene
Amidase that catalyzes the last step of diphthamide biosynthesis using ammonium and ATP. Diphthamide biosynthesis consists in the conversion of an L-histidine residue in the translation elongation factor (EEF2) to diphthamide (By similarity).