DPH1 Gene
protein-coding GIFtS: 53
GCID: GC17P001933
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DPH1 homolog (S. cerevisiae)(Previous names: diptheria toxin resistance protein required for diphthamide...) (Previous symbols: DPH2L, DPH2L1)
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Aliases for DPH1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| DPH1 Homolog (S. Cerevisiae)1 2 | | DPH-Like 1 (S. Cerevisiae)1 | | DPH2L11 2 3 5 | | Candidate Tumor Suppressor In Ovarian Cancer 12 | | OVCA11 2 3 5 | | Diphthamide Biosynthesis Protein 12 | | DPH2L1 2 3 | | Diptheria Toxin Resistance Protein Required For Diphthamide Biosynthesis(Saccharomyces)-Like 12 | | Diphthamide Biosynthesis Protein 2 Homolog-Like 12 3 | | Diptheria Toxin Resistance Protein Required For Diphthamide Biosynthesis-Like 12 | | Ovarian Cancer-Associated Gene 1 Protein2 3 | | Ovarian Tumor Suppressor Candidate 12 | | DPH-Like 12 3 | | HsDph13 | | DPH2-Like 12 3 | | Diphthamide Biosynthesis Protein 2-Like3 | | Diptheria Toxin Resistance Protein Required For Diphthamide Biosynthesis-Like 1(S. Cerevisiae)1 | | DPH1 Homolog3 |
Export aliases for DPH1 gene to outside databasesPrevious GC identifer: GC17P001881 |
Summaries for DPH1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for DPH1: Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2; MIM130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylationand inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH1 is 1 of several enzymes involved insynthesis of diphthamide in EEF2 (Liu et al., 2004 (PubMed 15485916)).(supplied by OMIM, Mar 2008) UniProtKB/Swiss-Prot: DPH1_HUMAN, Q9BZG8Function: Required for the first step in the synthesis of diphthamide, a post-translational modification of histidinewhich occurs in translation elongation factor 2. When overexpressed, suppresses colony formation ability and growthrate of ovarian cancer cells. Acts also as a tumor suppressor in lung and breast cancers (By similarity). Plays a rolein embryonic growth, organogenesis and postnatal survival (By similarity) Gene Wiki entry for DPH1
|
Genomic Views for DPH1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000017.10 NC_018928.1 NT_010718.16
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the DPH1 gene promoter: Max1 NF-1 NCX/Ncx SREBP-1c LUN-1 GATA-2 SREBP-1b SREBP-1a Chx10 c-Myc Other transcription factors
Search SABiosciences Chromatin IP Primers for DPH1
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DPH1 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 17p13.3 Ensembl cytogenetic band: 17p13.3 HGNC cytogenetic band: 17p13.3DPH1 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 17 GeneLoc Exon Structure GeneLoc location for GC17P001933: view genomic region
(about GC identifiers)
Start:
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1,933,404 bp from pter |
End:
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1,946,725 bp from pter |
Size:
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13,322 bases |
Orientation:
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plus strand |
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Proteins for DPH1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: DPH1_HUMAN, Q9BZG8 (See
protein sequence)Recommended Name: Diphthamide biosynthesis protein 1 Size: 443 amino acids; 48805 Da
Subunit: Interacts with DPH2 (By similarity). Interacts with RBM8A
Subcellular location: Nucleus. Cytoplasm. Note=Punctate, primarily perinuclear localization
Caution: It is uncertain whether Met-1 or Met-6 is the initiator
Secondary accessions: D3DTI3 Q16439 Q4VBA2 Q9BTW7 Q9UCY0Alternative splicing: 3 isoforms: Q9BZG8-1 Q9BZG8-2 Q9BZG8-3 Explore the universe of human proteins at neXtProt for DPH1: NX_Q9BZG8
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9BZG8 DPH1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001374.3 ENSEMBL proteins: ENSP00000263083 ENSP00000460431 ENSP00000458838 ENSP00000459308 ENSP00000458726 ENSP00000467936 ENSP00000460813 Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
DPH1 for ontologies About GeneDecksing
DPH1 Antibody Products: Assay Products for DPH1: |
Protein
Domains / Families for DPH1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
DPH1 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9BZG8ProtoNet protein and cluster: Q9BZG8 1 Blocks protein family: IPB002728 Diphthamide synthesis DPH2 protein
UniProtKB/Swiss-Prot: DPH1_HUMAN, Q9BZG8Similarity: Belongs to the DPH1/DPH2 family. DPH1 subfamily |
Function for DPH1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Function Summary: UniProtKB/Swiss-Prot: DPH1_HUMAN, Q9BZG8Function: Required for the first step in the synthesis of diphthamide, a post-translational modification of histidinewhich occurs in translation elongation factor 2. When overexpressed, suppresses colony formation ability and growthrate of ovarian cancer cells. Acts also as a tumor suppressor in lung and breast cancers (By similarity). Plays a rolein embryonic growth, organogenesis and postnatal survival (By similarity)
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DPH1 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DPH1 (see all 2) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: DPH1 (NM_001383) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for DPH1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DPH1  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DPH1 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005515 | protein binding |
-- | -- |
DPH1 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for DPH1: Animal Models: Mouse knock-outs for DPH1: Dph1tm2Bhr Dph1tm1Bhr 15/16 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Dph1) (see all 16):
DPH1 for phenotypes About GeneDecksing
|
Pathways & Interactions for DPH1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for DPH1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 23)
 5/51 Interacting proteins for DPH1 (Q9BZG83 ENSP000002630834) via UniProtKB, MINT, STRING, and/or I2D (see all 51)About this table
Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006412 | translation |
TAS | 8603384 | | GO:0008283 | cell proliferation |
IEA | -- | | GO:0017183 | peptidyl-diphthamide biosynthetic process from peptidyl-histidine |
IEA | -- |
DPH1 for ontologies About GeneDecksing
|
Drugs & Compounds for DPH1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
DPH1 for compounds About GeneDecksing
Browse Tocris compounds for DPH1 3 Novoseek chemical compound relationships for DPH1 gene About this table
Search CenterWatch for drugs/clinical trials and news about DPH1 
|
Transcripts for DPH1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for DPH1 gene: NM_001383.3 Unigene Cluster for DPH1: DPH1 homolog (S. cerevisiae) Hs.513856 [show with all ESTs]Unigene Representative Sequence: AK09053016 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000263083(uc002fts.3 uc002ftt.3 uc010cjx.3 uc010vqs.2) ENST00000575667 ENST00000571418 ENST00000572819 ENST00000576684 ENST00000576129 ENST00000570477 ENST00000570833 ENST00000576891 ENST00000572214 ENST00000570867(uc002ftv.3) ENST00000575998 ENST00000571710(uc002ftw.3) ENST00000572684 ENST00000572248 ENST00000575162
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DPH1 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DPH1 (see all 2) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: DPH1 (NM_001383) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for DPH1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DPH1  |
Additional cDNA sequence: AF073528.1 AF321875.1 AF321876.1 AK090530.1 AK297947.1 AK314015.1 BC003099.1 BC040696.2 BC041170.1 BC096086.1 BC096087.1 BC096088.1 BC096089.1 BT019878.1 S81752.1 U34880.1 17 DOTS entries: DT.453769 DT.91765825 DT.95158956 DT.95349153 DT.95158951 DT.100807851 DT.120980892 DT.97836300 DT.100738197 DT.100807846 DT.91765824 DT.120980964 DT.421591 DT.100807850 DT.91765823 DT.120980989 DT.95158962 24/384 AceView cDNA sequences (see all 384): AW874226 BM551324 AA595088 BM699273 CB132890 BC041170 H83609 CA430374 BM558769 CR600107 BM424280 CD674155 AI357934 BM809228 CA868138 BC003099 AI369646 BQ941225 AI753316 AI193095 AA632255 BI117197 AI131155 NM_080822 GeneLoc Exon Structure
5/13 Alternative Splicing Database (ASD) splice patterns (SP) for DPH1 (see all 13) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7a | · | 7b | · | 7c | · | 7d | ^ | 8a | · | 8b | · | 8c | · | 8d | ^ | 9a | · | 9b | ^ | 10 | ^ | 11a | · | 11b | ^ | 12a | · | 12b | · | 12c | ^ | |
| SP1: | |   | |   | |   | |   | |   | |   | |   | - |   | - |   | |   | |   | |   | - |   | - |   | - |   | - |   | |   | |   | |   | - |   | |   | - |   | |   | - |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | |   | - |   | - |   | - |   | |   | |   | |   | - |   | - |   | - |   | - |   | |   | |   | |   | - |   | |   | - |   | |   | - |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | - |   | |   | - |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | - |   | |   | |   | |   | |   |
| ExUns: | 13 | ^ | 14 | ^ | 15a | · | 15b | · | 15c | · | 15d | · | 15e | |
| SP1: | |   | - |   | |   | |   | |   | |   | |   | |
| SP2: | |   | - |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for DPH1
|
Expression for DPH1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| DPH1 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: GTGACTGCCA
About this image See DPH1 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for DPH1
SOURCE GeneReport for Unigene cluster: Hs.513856 UniProtKB/Swiss-Prot: DPH1_HUMAN, Q9BZG8Tissue specificity: Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen,thymus, mammary gland, colon, small intestine, testis and ovary. Reduced expression in primary breast and ovariantumors SABiosciences Custom PCR Arrays for DPH1
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DPH1 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat DPH1 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DPH1 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DPH1 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DPH1 |
Orthologs for DPH1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for DPH1 gene from 9/34 species (see all 34) About this table
ENSEMBL Gene Tree for DPH1 (if available) TreeFam Gene Tree for DPH1 (if available)  |
Paralogs for DPH1 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| -- |
Genomic Variants for DPH1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 17 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for DPH1 (1933404 - 1946725 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 2 variations for DPH1 2 CNVs: 67105 7142  | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DPH1 |
|
Disorders
/ Diseases for DPH1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
DPH1 for disorders About GeneDecksing
OMIM gene information: 603527
OMIM disorders: --
11 diseases for DPH1: About MalaCardsovarian cancer diphtheria miller-dieker syndrome esophageal squamous cell carcinoma squamous cell carcinoma sotos syndrome lissencephaly esophagitis breast cancer carcinoma malaria 1 disease from the University of Copenhagen DISEASES database for DPH1:Diphtheria 4 Novoseek disease relationships for DPH1 gene About this table
Export disorders for DPH1 gene to outside databases
|
Publications for DPH1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for DPH1 gene, integrated from 9 sources (see all 25): (articles sorted by number of sources associating them with DPH1) | |  | Utopia: connect your pdf to the dynamic world of online information |
- A cDNA from the ovarian cancer critical region of deletion on chromosome 17p13.3. (PubMed id 8603384)1, 2, 3, 9 Phillips N.J.... Deaven L.L. (1996)
- Identification of the proteins required for biosynthesis of diphthamide, the target of bacterial ADP-ribosylating toxins on translation elongation factor 2. (PubMed id 15485916)1, 3, 9 Liu S....Leppla S.H. (2004)
- Identification and structural analysis of human RBM8A and RBM8B: two highly conserved RNA-binding motif proteins that interact with OVCA1, a candidate tumor suppressor. (PubMed id 11013075)1, 2, 9 Salicioni A.M....Godwin A.K. (2000)
- Expression of OVCA1, a candidate tumor suppressor, is reduced in tumors and inhibits growth of ovarian cancer cells. (PubMed id 10519411)1, 2 Bruening W....Godwin A.K. (1999)
- Identification of two candidate tumor suppressor genes on chromosome 17p13.3. (PubMed id 8616839)1, 2 Schultz D.C....Godwin A.K. (1996)
- Cloning, structure, and expression of the mouse Ovca1 gene. (PubMed id 11527402)1, 9 Chen C.M. and Behringer R.R. (2001)
- The proteomic analysis of endogenous FAT10 substrates identifies p62/SQSTM1 as a substrate of FAT10ylation. (PubMed id 22797925)1 Aichem A....Groettrup M. (2012)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- OVCA1 inhibits the proliferation of epithelial ovaria n cancer cells by decreasing cyclin D1 and increasing p16. (PubMed id 21487939)1 Kong F....Zhao C. (2011)
|
External Searches for DPH1 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing DPH1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing DPH1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing DPH1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
|
About This Section
| Patent Information for DPH1 gene: Search GeneIP for patents involving DPH1
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for DPH1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
|
 | |
 | |
 |
| | | | Browse OriGene Antibodies | | OriGene shRNA RFP for DPH1 | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DPH1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DPH1 | | OriGene Protein Over-expression Lysate for DPH1 | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for DPH1 | | OriGene 3'-UTR Clone for DPH1 | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DPH1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DPH1 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | OriGene Purified Protein for DPH1 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for DPH1 | | OriGene Custom Protein Services for DPH1 | | OriGene Custom Immunoassay Development | | |
| |  |
 |
| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat DPH1 | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DPH1 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DPH1 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DPH1 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DPH1 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DPH1 |
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| | | Search Tocris compounds for DPH1 |
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 | | DPH1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DPH1 |
|  |  |  | | | ThermoFisher Antibodies for DPH1 |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DPH1 |
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