Aliases for DPF2 Gene
External Ids for DPF2 Gene
Previous HGNC Symbols for DPF2 Gene
Previous GeneCards Identifiers for DPF2 Gene
The protein encoded by this gene is a member of the d4 domain family, characterized by a zinc finger-like structural motif. This protein functions as a transcription factor which is necessary for the apoptotic response following deprivation of survival factors. It likely serves a regulatory role in rapid hematopoietic cell growth and turnover. This gene is considered a candidate gene for multiple endocrine neoplasia type I, an inherited cancer syndrome involving multiple parathyroid, enteropancreatic, and pituitary tumors. [provided by RefSeq, Jul 2008]
GeneCards Summary for DPF2 Gene
DPF2 (Double PHD Fingers 2) is a Protein Coding gene. Diseases associated with DPF2 include multiple endocrine neoplasia. Among its related pathways are TNF-alpha/NF-kB Signaling Pathway. GO annotations related to this gene include RNA polymerase II core promoter proximal region sequence-specific DNA binding. An important paralog of this gene is PHF10.
UniProtKB/Swiss-Prot for DPF2 Gene
May be a transcription factor required for the apoptosis response following survival factor withdrawal from myeloid cells. Might also have a role in the development and maturation of lymphoid cells.