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Aliases for DPCR1 Gene

Aliases for DPCR1 Gene

  • Diffuse Panbronchiolitis Critical Region 1 2 3
  • C6orf37 4 6
  • PBLT 3 4
  • Diffuse Panbronchiolitis Critical Region Protein 1 3

External Ids for DPCR1 Gene

Previous GeneCards Identifiers for DPCR1 Gene

  • GC06P030975
  • GC06P030689
  • GC06P031025
  • GC06P031026
  • GC06P030908

Summaries for DPCR1 Gene

GeneCards Summary for DPCR1 Gene

DPCR1 (Diffuse Panbronchiolitis Critical Region 1) is a Protein Coding gene. Diseases associated with DPCR1 include panbronchiolitis, diffuse.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for DPCR1 Gene

Genomics for DPCR1 Gene

Regulatory Elements for DPCR1 Gene

Genomic Location for DPCR1 Gene

30,940,972 bp from pter
30,954,221 bp from pter
13,250 bases
Plus strand

Genomic View for DPCR1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for DPCR1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

Proteins for DPCR1 Gene

  • Protein details for DPCR1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Diffuse panbronchiolitis critical region protein 1
    Protein Accession:
    Secondary Accessions:
    • C9IZC0
    • Q658M7
    • Q8WYN2

    Protein attributes for DPCR1 Gene

    517 amino acids
    Molecular mass:
    56347 Da
    Quaternary structure:
    No Data Available
    • Sequence=CAH56248.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305}; Sequence=CAI18455.2; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

    Alternative splice isoforms for DPCR1 Gene


neXtProt entry for DPCR1 Gene

Proteomics data for DPCR1 Gene at MOPED

Post-translational modifications for DPCR1 Gene

  • Glycosylation at Asn88, Asn124, and Asn338
  • Modification sites at PhosphoSitePlus

Other Protein References for DPCR1 Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

No data available for DME Specific Peptides for DPCR1 Gene

Domains for DPCR1 Gene

Protein Domains for DPCR1 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with DPCR1: view

No data available for Gene Families and UniProtKB/Swiss-Prot for DPCR1 Gene

Function for DPCR1 Gene

Animal Model Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for DPCR1

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for DPCR1 Gene

Localization for DPCR1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for DPCR1 Gene

Membrane; Single-pass type I membrane protein.

Subcellular locations from

Jensen Localization Image for DPCR1 Gene COMPARTMENTS Subcellular localization image for DPCR1 gene
Compartment Confidence
cytosol 2
plasma membrane 2
extracellular 1
mitochondrion 1
nucleus 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for DPCR1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with DPCR1: view

Pathways for DPCR1 Gene

SuperPathways for DPCR1 Gene

No Data Available

Interacting Proteins for DPCR1 Gene

Gene Ontology (GO) - Biological Process for DPCR1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:1903955 positive regulation of protein targeting to mitochondrion IMP 24270810
genes like me logo Genes that share ontologies with DPCR1: view

No data available for Pathways by source for DPCR1 Gene

Transcripts for DPCR1 Gene

mRNA/cDNA for DPCR1 Gene

Unigene Clusters for DPCR1 Gene

Diffuse panbronchiolitis critical region 1:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for DPCR1

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for DPCR1 Gene

No ASD Table

Relevant External Links for DPCR1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for DPCR1 Gene

mRNA expression in normal human tissues for DPCR1 Gene

mRNA differential expression in normal tissues according to GTEx for DPCR1 Gene

This gene is overexpressed in Stomach (42.3) and Esophagus - Mucosa (5.9).

Protein differential expression in normal tissues for DPCR1 Gene

This gene is overexpressed in Stomach (63.9).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for DPCR1 Gene

SOURCE GeneReport for Unigene cluster for DPCR1 Gene Hs.631993

mRNA Expression by UniProt/SwissProt for DPCR1 Gene

Tissue specificity: Detected in lung, esophagus, stomach, rectum, skin, cervix, testis, kidney, uterus and small intestine.
genes like me logo Genes that share expressions with DPCR1: view

Expression partners for DPCR1 Gene

* - Elite partner

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery for DPCR1 Gene

Orthologs for DPCR1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for DPCR1 Gene

Organism Taxonomy Gene Similarity Type Details
(Canis familiaris)
Mammalia LOC102152456 35
  • 64.92 (n)
  • 43 (a)
DPCR1 36
  • 37 (a)
(Mus musculus)
Mammalia Dpcr1 35
  • 61.07 (n)
  • 43.49 (a)
Dpcr1 16
Dpcr1 36
  • 41 (a)
(Rattus norvegicus)
Mammalia Dpcr1 35
  • 59.5 (n)
  • 43.84 (a)
(Pan troglodytes)
Mammalia DPCR1 36
  • 87 (a)
Species with no ortholog for DPCR1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for DPCR1 Gene

Gene Tree for DPCR1 (if available)
Gene Tree for DPCR1 (if available)

Paralogs for DPCR1 Gene

No data available for Paralogs for DPCR1 Gene

Variants for DPCR1 Gene

Sequence variations from dbSNP and Humsavar for DPCR1 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type MAF
rs2243739 -- 30,941,631(+) atttt(C/T)ttgta intron-variant
rs2247178 -- 30,948,941(+) ATAAC(A/G)CCAGC synonymous-codon, reference
rs2517449 -- 30,951,924(-) GGCCA(A/G)TGTGG synonymous-codon, reference
rs2517451 -- 30,946,974(-) GCAAC(A/G)TTTCT intron-variant
rs2532922 -- 30,950,553(-) TGCTG(A/G)GGATG missense, reference

Structural Variations from Database of Genomic Variants (DGV) for DPCR1 Gene

Variant ID Type Subtype PubMed ID
esv2731791 CNV Deletion 23290073
esv2670269 CNV Deletion 23128226
nsv525438 CNV Gain 19592680
nsv823473 CNV Loss 20364138
nsv462744 CNV Loss 19166990

Relevant External Links for DPCR1 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for DPCR1 Gene

Disorders for DPCR1 Gene

MalaCards: The human disease database

MalaCards: The human disease database.

Search for DPCR1 Gene in MalaCards »

(1) Disease for DPCR1 Gene

Relevant External Links for DPCR1

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
genes like me logo Genes that share disorders with DPCR1: view

No data available for OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for DPCR1 Gene

Publications for DPCR1 Gene

  1. Identification of novel candidate genes in the diffuse panbronchiolitis critical region of the class I human MHC. (PMID: 12185533) Matsuzaka Y. … Inoko H. (Immunogenetics 2002) 2 3 4
  2. Common genetic variation and the control of HIV-1 in humans. (PMID: 20041166) Fellay J. … Goldstein D.B. (PLoS Genet. 2009) 3 48
  3. Fine localization of a major disease-susceptibility locus for diffuse panbronchiolitis. (PMID: 10677310) Keicho N. … Kudoh S. (Am. J. Hum. Genet. 2000) 2 3
  4. High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions. (PMID: 19851445) Barcellos L.F. … Criswell L.A. (PLoS Genet. 2009) 3 48
  5. Rapid evolution of major histocompatibility complex class I genes in primates generates new disease alleles in humans via hitchhiking diversity. (PMID: 16702430) Shiina T. … Bahram S. (Genetics 2006) 3 4

Products for DPCR1 Gene

Sources for DPCR1 Gene

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