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Aliases for DPCD Gene

Aliases for DPCD Gene

  • Deleted In Primary Ciliary Dyskinesia Homolog (Mouse) 2 3
  • Deleted In A Mouse Model Of Primary Ciliary Dyskinesia 3
  • RP11-529I10.4 3
  • Protein DPCD 3

External Ids for DPCD Gene

Summaries for DPCD Gene

GeneCards Summary for DPCD Gene

DPCD (Deleted In Primary Ciliary Dyskinesia Homolog (Mouse)) is a Protein Coding gene.

UniProtKB/Swiss-Prot for DPCD Gene

  • May play a role in the formation or function of ciliated cells.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for DPCD Gene

Genomics for DPCD Gene

Genomic Location for DPCD Gene

101,570,560 bp from pter
101,609,668 bp from pter
39,109 bases
Plus strand

Genomic View for DPCD Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for DPCD Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for DPCD Gene

No data available for Regulatory Elements for DPCD Gene

Proteins for DPCD Gene

  • Protein details for DPCD Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein DPCD
    Protein Accession:
    Secondary Accessions:
    • A8K289
    • Q6QNL3
    • Q8N5R1
    • Q9UFY6

    Protein attributes for DPCD Gene

    203 amino acids
    Molecular mass:
    23240 Da
    Quaternary structure:
    No Data Available

neXtProt entry for DPCD Gene

Proteomics data for DPCD Gene at MOPED

Post-translational modifications for DPCD Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for DPCD Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for DPCD Gene

Domains for DPCD Gene

Protein Domains for DPCD Gene



  • Belongs to the DPCD family.:
    • Q9BVM2
genes like me logo Genes that share domains with DPCD: view

No data available for Gene Families for DPCD Gene

Function for DPCD Gene

Molecular function for DPCD Gene

UniProtKB/Swiss-Prot Function: May play a role in the formation or function of ciliated cells.

Gene Ontology (GO) - Molecular Function for DPCD Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 16189514
genes like me logo Genes that share ontologies with DPCD: view
genes like me logo Genes that share phenotypes with DPCD: view

Animal Models for DPCD Gene

MGI Knock Outs for DPCD:

No data available for Enzyme Numbers (IUBMB) , miRNA , Transcription Factor Targeting and HOMER Transcription for DPCD Gene

Localization for DPCD Gene

Subcellular locations from

Jensen Localization Image for DPCD Gene COMPARTMENTS Subcellular localization image for DPCD gene
Compartment Confidence
cytosol 3
mitochondrion 1
nucleus 1
peroxisome 1
plasma membrane 1

Gene Ontology (GO) - Cellular Components for DPCD Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IDA 21630459
genes like me logo Genes that share ontologies with DPCD: view

Pathways for DPCD Gene

SuperPathways for DPCD Gene

No Data Available

Gene Ontology (GO) - Biological Process for DPCD Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003351 epithelial cilium movement IEA --
GO:0007283 spermatogenesis IEA --
GO:0007368 determination of left/right symmetry IEA --
GO:0021591 ventricular system development --
GO:0021670 lateral ventricle development IEA --
genes like me logo Genes that share ontologies with DPCD: view

No data available for Pathways by source for DPCD Gene

Transcripts for DPCD Gene

Unigene Clusters for DPCD Gene

Deleted in primary ciliary dyskinesia homolog (mouse):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for DPCD Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b · 5c ^ 6 ^ 7a · 7b · 7c
SP1: - - - -
SP2: - - -
SP3: -
SP4: -

Relevant External Links for DPCD Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for DPCD Gene

mRNA expression in normal human tissues for DPCD Gene

mRNA differential expression in normal tissues according to GTEx for DPCD Gene

This gene is overexpressed in Testis (5.9).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for DPCD Gene

SOURCE GeneReport for Unigene cluster for DPCD Gene Hs.658128

mRNA Expression by UniProt/SwissProt for DPCD Gene

Tissue specificity: Highly expressed in the testis. Weakly expressed in pancreas, skeletal muscle and heart. Expression increases during ciliated cell differentiation.
genes like me logo Genes that share expressions with DPCD: view

Orthologs for DPCD Gene

This gene was present in the common ancestor of animals.

Orthologs for DPCD Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia DPCD 36
  • 94.25 (n)
  • 93 (a)
  • 98 (a)
(Bos Taurus)
Mammalia DPCD 36
  • 88.01 (n)
  • 88.67 (a)
  • 89 (a)
(Canis familiaris)
Mammalia DPCD 36
  • 90.15 (n)
  • 91.13 (a)
  • 91 (a)
(Mus musculus)
Mammalia Dpcd 36
  • 86.54 (n)
  • 88.18 (a)
Dpcd 16
Dpcd 37
  • 88 (a)
(Monodelphis domestica)
Mammalia DPCD 37
  • 80 (a)
(Ornithorhynchus anatinus)
Mammalia DPCD 37
  • 76 (a)
(Gallus gallus)
Aves DPCD 36
  • 73.07 (n)
  • 70.44 (a)
  • 70 (a)
(Anolis carolinensis)
Reptilia DPCD 37
  • 69 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.8292 36
tropical clawed frog
(Silurana tropicalis)
Amphibia dpcd 36
  • 66.17 (n)
  • 70.44 (a)
Str.10966 36
(Danio rerio)
Actinopterygii dpcd 36
  • 61.33 (n)
  • 63 (a)
dpcd 37
  • 63 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP012517 36
  • 45.67 (n)
  • 36 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG13901 36
  • 51.1 (n)
  • 41.62 (a)
CG13901 37
  • 37 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.1143 37
  • 49 (a)
Species with no ortholog for DPCD:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for DPCD Gene

Gene Tree for DPCD (if available)
Gene Tree for DPCD (if available)

Paralogs for DPCD Gene

No data available for Paralogs for DPCD Gene

Variants for DPCD Gene

Sequence variations from dbSNP and Humsavar for DPCD Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type MAF
rs7006 - 101,608,897(-) TCAGC(A/G)AGGCG missense, reference
rs13246 -- 101,609,483(-) TAAGG(C/T)TCAGG utr-variant-3-prime
rs1861926 -- 101,606,989(-) AAGAG(C/G)AATGG intron-variant
rs2241290 -- 101,608,398(-) GCTGG(A/G)GCCCT intron-variant
rs3095792 -- 101,608,030(-) TTACC(A/T)AAAAG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for DPCD Gene

Variant ID Type Subtype PubMed ID
esv2750847 CNV Gain 17911159
nsv895967 CNV Gain 21882294
nsv526529 CNV Loss 19592680
nsv527185 CNV Loss 19592680
esv2677024 CNV Deletion 23128226
esv23858 CNV Loss 19812545

Relevant External Links for DPCD Gene

HapMap Linkage Disequilibrium report

Disorders for DPCD Gene

(2) University of Copenhagen DISEASES for DPCD Gene

Relevant External Links for DPCD

Human Genome Epidemiology (HuGE) Navigator
genes like me logo Genes that share disorders with DPCD: view

No data available for UniProtKB/Swiss-Prot for DPCD Gene

Publications for DPCD Gene

  1. Investigation of the possible role of a novel gene, DPCD, in primary ciliary dyskinesia. (PMID: 14630615) Zariwala M. … Ostrowski L.E. (Am. J. Respir. Cell Mol. Biol. 2004) 2 3 4
  2. Towards a proteome-scale map of the human protein-protein interaction network. (PMID: 16189514) Rual J.F. … Vidal M. (Nature 2005) 3
  3. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PMID: 16385451) Grupe A. … Goate A. (Am. J. Hum. Genet. 2006) 3
  4. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3
  5. Large-scale mapping of human protein-protein interactions by mass spectrometry. (PMID: 17353931) Ewing R.M. … Figeys D. (Mol. Syst. Biol. 2007) 3

Products for DPCD Gene

Sources for DPCD Gene

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