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DOPEY2 Gene

protein-coding   GIFtS: 48
GCID: GC21P037529

Dopey Family Member 2

(Previous name: chromosome 21 open reading frame 5)
(Previous symbol: C21orf5)
  Search for DOPEY2
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Dopey Family Member 21 2     Chromosome 21 Open Reading Frame 51
C21orf51 2 3     Homolog Of Yeast DOP12
21orf52 5     Protein Dopey-22
KIAA09333 5     

External Ids:    HGNC: 12911   Entrez Gene: 99802   Ensembl: ENSG000001421977   OMIM: 6048035   UniProtKB: Q9Y3R53   

Export aliases for DOPEY2 gene to outside databases

Previous GC identifers: GC21P036459 GC21P023014


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for DOPEY2 Gene:
DOPEY2 (dopey family member 2) is a protein-coding gene. An important paralog of this gene is DOPEY1.

UniProtKB/Swiss-Prot: DOP2_HUMAN, Q9Y3R5
Function: May be involved in protein traffic between late Golgi and early endosomes (By similarity)

Gene Wiki entry for DOPEY2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000021.8  NT_011512.12  NC_018932.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the DOPEY2 gene promoter:
         RP58   AML1a   NCX/Ncx   FOXD1   E47   AREB6   PPAR-gamma1   COMP1   PPAR-gamma2   ATF6   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): DOPEY2 promoter sequence
   Search Chromatin IP Primers for DOPEY2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat DOPEY2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 21q22.2   Ensembl cytogenetic band:  21q22.12   HGNC cytogenetic band: 21q22.2

DOPEY2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DOPEY2 gene location

GeneLoc information about chromosome 21         GeneLoc Exon Structure

GeneLoc location for GC21P037529:  view genomic region     (about GC identifiers)

Start:
37,529,080 bp from pter      End:
37,666,572 bp from pter
Size:
137,493 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: DOP2_HUMAN, Q9Y3R5 (See protein sequence)
Recommended Name: Protein dopey-2  
Size: 2298 amino acids; 258230 Da
Developmental stage: Abundantly expressed in developing central nervous system, with highest levels in cerebellum
and lowest in telencephalon
Secondary accessions: D3DSG5 Q6PJQ7 Q9UEZ3
Alternative splicing: 2 isoforms:  Q9Y3R5-1   Q9Y3R5-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for DOPEY2: NX_Q9Y3R5

Explore proteomics data for DOPEY2 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys23, Lys420
  • Modification sites at PhosphoSitePlus

  • See DOPEY2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_005119.2  
    ENSEMBL proteins: 
     ENSP00000270190   ENSP00000382104  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR007249 Dopey_N

    Graphical View of Domain Structure for InterPro Entry Q9Y3R5

    ProtoNet protein and cluster: Q9Y3R5

    UniProtKB/Swiss-Prot: DOP2_HUMAN, Q9Y3R5
    Similarity: Belongs to the dopey family


    Find genes that share domains with DOPEY2           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: DOP2_HUMAN, Q9Y3R5
    Function: May be involved in protein traffic between late Golgi and early endosomes (By similarity)

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
         
    Find genes that share ontologies with DOPEY2           About GenesLikeMe


    Phenotypes:
         2 MGI mutant phenotypes (inferred from 1 allele(MGI details for Dopey2):
     integument  limbs/digits/tail 

    Find genes that share phenotypes with DOPEY2           About GenesLikeMe

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for DOPEY2
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for DOPEY2
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    miRNA
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    miRTarBase miRNAs that target DOPEY2:
    hsa-mir-335-5p (MIRT018940), hsa-mir-92a-3p (MIRT049417)

    Block miRNA regulation of human, mouse, rat DOPEY2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate DOPEY2 (see all 15):
    hsa-miR-3910 hsa-miR-3650 hsa-miR-1321 hsa-miR-539 hsa-miR-3065-5p hsa-miR-624 hsa-miR-29b-1* hsa-miR-3162-5p
    SwitchGear 3'UTR luciferase reporter plasmidDOPEY2 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat DOPEY2

    Gene Editing
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DOPEY2


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    golgi apparatus3
    plasma membrane3
    cytosol1
    peroxisome1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000139Golgi membrane ISS16301316
    GO:0070062extracellular vesicular exosome IDA19056867

    Find genes that share ontologies with DOPEY2           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for DOPEY2
    Interactions:

        Search GeneGlobe Interaction Network for DOPEY2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 24)

    Selected Interacting proteins for DOPEY2 (ENSP000003821044) via UniProtKB, MINT, STRING, and/or I2D (see all 24)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TRIP12ENSP000002839434STRING: ENSP00000283943
    MON2ENSP000003772524STRING: ENSP00000377252
    ARL1ENSP000002616364STRING: ENSP00000261636
    HECTD1ENSP000003822694STRING: ENSP00000382269
    DGAT2ENSP000002280274STRING: ENSP00000228027
    About this table

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006895Golgi to endosome transport ISS16301316
    GO:0007029endoplasmic reticulum organization ISS16301316
    GO:0007275multicellular organismal development NAS10950924
    GO:0015031protein transport IEA--

    Find genes that share ontologies with DOPEY2           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for DOPEY2 (DOP2)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for DOPEY2 gene: 
    NM_005128.2  

    Unigene Cluster for DOPEY2:

    Dopey family member 2
    Hs.204575  [show with all ESTs]
    Unigene Representative Sequence: NM_005128
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000270190 ENST00000399151(uc002yvh.3 uc002yvg.3 uc011aeb.2)
    ENST00000492760 ENST00000463668
    miRNA
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    Block miRNA regulation of human, mouse, rat DOPEY2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate DOPEY2 (see all 15):
    hsa-miR-3910 hsa-miR-3650 hsa-miR-1321 hsa-miR-539 hsa-miR-3065-5p hsa-miR-624 hsa-miR-29b-1* hsa-miR-3162-5p
    SwitchGear 3'UTR luciferase reporter plasmidDOPEY2 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat DOPEY2
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    Primer
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat DOPEY2
      QuantiTect SYBR Green Assays in human, mouse, rat DOPEY2
      QuantiFast Probe-based Assays in human, mouse, rat DOPEY2

    Additional mRNA sequence: 

    AB023150.2 AJ001857.1 AJ237839.2 AK025095.1 AK026478.1 BC012791.2 

    6 DOTS entries:

    DT.40285384  DT.100747276  DT.101980259  DT.121139296  DT.40223446  DT.91889911 

    Selected AceView cDNA sequences (see all 75):

    BU152648 AA931930 CR613258 AL546074 BX091550 BM762343 BC012791 NM_005128 
    AA987490 BE465311 AB023150 BX643639 AI510780 BQ927561 AK025095 AW085802 
    AL571566 BE551040 AW575790 BM469636 BF508650 BI457392 AJ237839 AW070676 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    DOPEY2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    DOPEY2 Expression
    About this image

    DOPEY2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    DOPEY2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.204575

    UniProtKB/Swiss-Prot: DOP2_HUMAN, Q9Y3R5
    Tissue specificity: Ubiquitously expressed. Overexpressed in lymphoblasts from Down syndrome patients

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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for DOPEY2 gene from Selected species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Dopey21 , 5 dopey family member 21, 5 83.1(n)1
    86.57(a)1
      16 (54.63 cM)5
    700281  NM_027293.11  NP_081569.11 
     937119075 
    chicken
    (Gallus gallus)
    Aves DOPEY21 dopey family member 2 71.57(n)
    76.33(a)
      100858524  XM_003640493.2  XP_003640541.1 
    lizard
    (Anolis carolinensis)
    Reptilia DOPEY26
    dopey family member 2
    63(a)
    1 ↔ 1
    3(141489941-141579631)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia dopey21 dopey family member 2 68.14(n)
    70.83(a)
      100125059  XM_004912123.1  XP_004912180.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc636222 hypothetical protein MGC63622 74.4(n)   393582  BC056791.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG150996
    --
    23(a)
    1 → many
    2R(14724326-14734124)
    worm
    (Caenorhabditis elegans)
    Secernentea pad-16
    Protein PAD-1 (pad-1) mRNA, complete cds
    21(a)
    1 → many
    I(12878595-12902804) WBGene00003905
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes DOP16
    Golgi-localized, leucine-zipper domain containing ...
    18(a)
    1 → many
    IV(734901-739997) YDR141C


    ENSEMBL Gene Tree for DOPEY2 (if available)
    TreeFam Gene Tree for DOPEY2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for DOPEY2 gene
    DOPEY12  
    1 SIMAP similar gene for DOPEY2 using alignment to 2 protein entries:     DOP2_HUMAN (see all proteins):
    DOPEY1

    Find genes that share paralogs with DOPEY2           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for DOPEY2 (see all 3541)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 21 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs2074778701,2
    Cuntested137627400(+) ATGCTA/G/TTCACT 1 -- int10--------
    rs114421931,2
    C--37534846(+) CTTTC-/TTTTTT 1 -- us2k1 trp30--------
    rs1841755451,2
    --37534883(+) ACCCAG/TGCTGG 1 -- us2k10--------
    rs119089771,2
    C,F,H--37534899(+) AGTGGC/TGCAGT 1 -- us2k19Minor allele frequency- T:0.37WA NA CSA EA 372
    rs1477517631,2
    --37535160(+) TATTTA/GGCAGT 1 -- us2k10--------
    rs37613551,2
    C,F,H--37535219(+) TCTGGC/TGCTGG 1 -- us2k114Minor allele frequency- T:0.22NA WA CSA EA 380
    rs1892436331,2
    --37535370(+) CCAGGA/CGCGGT 1 -- us2k10--------
    rs1491332601,2
    --37535455(+) CTGACC/TAACAC 1 -- us2k10--------
    rs1422922801,2
    --37535471(+) ACCCCA/GTCTCT 1 -- us2k10--------
    rs1512722891,2
    --37535513(+) GGCACA/GTGCCT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for DOPEY2 (37529080 - 37666572 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10 variations for DOPEY2:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2670565CNV Deletion23128226
    esv2723391CNV Deletion23290073
    esv2456821CNV Deletion19546169
    nsv510797CNV Loss20534489
    esv33578CNV Loss17666407
    esv2751928CNV Gain17911159
    nsv459249CNV Gain19166990
    esv2751927CNV Gain17911159
    nsv913734CNV Gain21882294
    nsv516175CNV Gain19592680

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing DOPEY2
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 604803    OMIM disorders: --

    1 disease from the University of Copenhagen DISEASES database for DOPEY2:
    Down syndrome

    Find genes that share disorders with DOPEY2           About GenesLikeMe

    Genetic Association Database (GAD): DOPEY2
    Human Genome Epidemiology (HuGE) Navigator: DOPEY2 (1 document)

    Export disorders for DOPEY2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for DOPEY2 gene, integrated from 10 sources (see all 19):
    (articles sorted by number of sources associating them with DOPEY2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Morphogenesis in Aspergillus nidulans requires Dopey (DopA), a member of a novel family of leucine zipper-like proteins conserved from yeast to humans. (PubMed id 10931277)1, 2, 3 Pascon R.C. and Miller B.L. (Mol. Microbiol. 2000)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    3. Mon2, a relative of large Arf exchange factors, recruits Dop1 to the Golgi apparatus. (PubMed id 16301316)1, 3 Gillingham A.K.... Munro S. (J. Biol. Chem. 2006)
    4. C21orf5, a human candidate gene for brain abnormalities and mental retardation in Down syndrome. (PubMed id 16276086)1, 2 Rachidi M.... Delabar J.-M. (Cytogenet. Genome Res. 2006)
    5. C21orf5, a new member of Dopey family involved in morphogenesis, could participate in neurological alterations and mental retardation in Down syndrome. (PubMed id 16303751)1, 3 Rachidi M....Delabar J.M. (DNA Res. 2005)
    6. The differentially expressed C21orf5 gene in the medial temporal-lobe system could play a role in mental retardation in Down syndrome and transgenic mice. (PubMed id 12767918)1, 2 Lopes C.... Rachidi M. (Biochem. Biophys. Res. Commun. 2003)
    7. Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. (PubMed id 12168954)1, 2 Nakajima D.... Nagase T. (DNA Res. 2002)
    8. C21orf5, a novel human chromosome 21 gene, has a Caenorhabditis elegans ortholog (pad-1) required for embryonic patterning. (PubMed id 10950924)1, 2 Guipponi M.... Antonarakis S.E. (Genomics 2000)
    9. The DNA sequence of human chromosome 21. (PubMed id 10830953)1, 2 Hattori M.... Yaspo M.-L. (Nature 2000)
    10. Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10231032)1, 2 Nagase T.... Ohara O. (DNA Res. 1999)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
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      Query String
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    OMIM
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 9980 HGNC: 1291 AceView: C21orf5 Ensembl:ENSG00000142197 euGenes: HUgn9980
    ECgene: DOPEY2 H-InvDB: DOPEY2

    (According to HUGE)
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    HUGE: KIAA0933

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for DOPEY2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for DOPEY2 gene:
    Search GeneIP for patents involving DOPEY2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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