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DONSON Gene

protein-coding   GIFtS: 49
GCID: GC21M034948

Downstream Neighbor Of SON


(Previous symbol: C21orf60)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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This gene clusters with an RNA gene
Subcategory (RNA class): antisense

Quality score for the ORGUL clustered with this gene is 3

Aliases
Downstream Neighbor Of SON1 2
C21orf601 2 3
B172 3
Protein Downstream Neighbor Of Son2

External Ids:    HGNC: 29931   Entrez Gene: 299802   Ensembl: ENSG000001591477   OMIM: 6114285   UniProtKB: Q9NYP33   
ORGUL members:         

Export aliases for DONSON gene to outside databases

Previous GC identifers: GC21U990030 GC21M031608 GC21M033870 GC21M033873 GC21M020428


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for DONSON Gene:
This gene lies downstream of the SON gene and spans 10 kb on chromosome 21. The function of this gene is unknown.
(provided by RefSeq, Jul 2008)

GeneCards Summary for DONSON Gene:
DONSON (downstream neighbor of SON) is a protein-coding gene. Diseases associated with DONSON include myasthenia gravis, and down syndrome.

UniProtKB/Swiss-Prot: DONS_HUMAN, Q9NYP3
Function: Essential for DNA amplification in the ovary and required for cell proliferation during development (By
similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000021.9  NC_018932.2  NT_011512.12  
Regulatory elements:
   Regulatory transcription factor binding sites in the DONSON gene promoter:
         Oct-B1   oct-B3   oct-B2   Nkx2-5   NF-E2 p45   C/EBPalpha   POU2F1   POU2F1a   IRF-7A   NF-E2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidDONSON promoter sequence
   Search Chromatin IP Primers for DONSON

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat DONSON


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 21q22.1   Ensembl cytogenetic band:  21q22.11   HGNC cytogenetic band: 21q22.1

DONSON Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DONSON gene location

GeneLoc information about chromosome 21         GeneLoc Exon Structure

GeneLoc location for GC21M034948:  view genomic region     (about GC identifiers)

Start:
34,931,848 bp from pter      End:
34,961,014 bp from pter
Size:
29,167 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: DONS_HUMAN, Q9NYP3 (See protein sequence)
Recommended Name: Protein downstream neighbor of Son  
Size: 566 amino acids; 62747 Da
Secondary accessions: Q8NC53 Q9NSR9 Q9NVZ5 Q9NYP1 Q9NYP2
Alternative splicing: 3 isoforms:  Q9NYP3-1   Q9NYP3-2   Q9NYP3-3   (May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay)

Explore the universe of human proteins at neXtProt for DONSON: NX_Q9NYP3

Explore proteomics data for DONSON at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See DONSON Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_060083.1  
    ENSEMBL proteins: 
     ENSP00000476496   ENSP00000304716   ENSP00000394276   ENSP00000415191   ENSP00000307143  
     ENSP00000392014   ENSP00000392405   ENSP00000408788   ENSP00000399535   ENSP00000398329  
     ENSP00000401082  

    DONSON Human Recombinant Protein Products:

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    DONSON Assay Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR024861 Donson

    Graphical View of Domain Structure for InterPro Entry Q9NYP3

    ProtoNet protein and cluster: Q9NYP3

    UniProtKB/Swiss-Prot: DONS_HUMAN, Q9NYP3
    Similarity: Belongs to the DONSON family


    DONSON for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: DONS_HUMAN, Q9NYP3
    Function: Essential for DNA amplification in the ovary and required for cell proliferation during development (By
    similarity)

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
         
    DONSON for ontologies           About GeneDecksing


    Phenotypes:
         3 GenomeRNAi human phenotypes for DONSON:
     Abundance of large cells with   Decreased number of cells in m  Increased gamma-H2AX phosphory 

         2 MGI mutant phenotypes (inferred from 1 allele(MGI details for Donson):
     immune system  mortality/aging 

    DONSON for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for DONSON
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for DONSON

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for DONSON
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for DONSON

    miRNA
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    miRTarBase miRNAs that target DONSON:
    hsa-mir-26b-5p (MIRT028777), hsa-mir-23b-3p (MIRT046340), hsa-mir-193b-3p (MIRT016303)

    Block miRNA regulation of human, mouse, rat DONSON using miScript Target Protectors
    6 qRT-PCR Assays for microRNAs that regulate DONSON:
    hsa-miR-145* hsa-miR-183* hsa-miR-502-5p hsa-miR-9 hsa-miR-449c* hsa-miR-1238
    SwitchGear 3'UTR luciferase reporter plasmidDONSON 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for DONSON
    Predesigned siRNA for gene silencing in human, mouse, rat DONSON

    Gene Editing
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    OriGene ORF clones in mouse, rat for DONSON
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    GenScript: all cDNA clones in your preferred vector: DONSON (NM_017613)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for DONSON
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DONSON

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for DONSON 
    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DONSON


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    DONS_HUMAN, Q9NYP3: Nucleus (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus2
    cytosol1
    mitochondrion1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005575cellular_component ND--
    GO:0005634nucleus IEA--

    DONSON for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for DONSON
    Interactions:

        Search GeneGlobe Interaction Network for DONSON

    STRING Interaction Network Preview (showing 5 interactants - click image to see 6)

    Selected Interacting proteins for DONSON (Q9NYP33 ENSP000003071434) via UniProtKB, MINT, STRING, and/or I2D (see all 6)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PSMA3P257883, ENSP000002164554I2D: score=1 STRING: ENSP00000216455
    ASF1AENSP000002295954STRING: ENSP00000229595
    ASF1BENSP000002633824STRING: ENSP00000263382
    RPS6ENSP000003697574STRING: ENSP00000369757
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007275multicellular organismal development IEA--
    GO:0008150biological_process ND--

    DONSON for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for DONSON (DONS)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for DONSON gene (3 alternative transcripts): 
    NM_145794.1  NM_145795.1  NM_017613.3  

    Unigene Cluster for DONSON:

    Downstream neighbor of SON
    Hs.436341  [show with all ESTs]
    Unigene Representative Sequence: NM_017613
    13 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000439593 ENST00000303113(uc002ysi.1) ENST00000453626 ENST00000457359
    ENST00000303071(uc002ysj.3 uc002ysk.3 uc002ysm.3) ENST00000417871
    ENST00000460557 ENST00000444517 ENST00000442660 ENST00000437395 ENST00000432378
    ENST00000440810 ENST00000462566
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat DONSON using miScript Target Protectors
    6 qRT-PCR Assays for microRNAs that regulate DONSON:
    hsa-miR-145* hsa-miR-183* hsa-miR-502-5p hsa-miR-9 hsa-miR-449c* hsa-miR-1238
    SwitchGear 3'UTR luciferase reporter plasmidDONSON 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for DONSON
    Predesigned siRNA for gene silencing in human, mouse, rat DONSON
    Clone
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    OriGene clones in human, mouse for DONSON (see all 7)
    OriGene ORF clones in mouse, rat for DONSON
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: DONSON (NM_017613)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for DONSON
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DONSON
    Primer
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    OriGene qPCR primer pairs and template standards for DONSON
    OriGene qSTAR qPCR primer pairs in human, mouse for DONSON
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat DONSON
      QuantiTect SYBR Green Assays in human, mouse, rat DONSON
      QuantiFast Probe-based Assays in human, mouse, rat DONSON

    Additional mRNA sequence: 

    AF232673.1 AK074964.1 BC048266.1 

    15 DOTS entries:

    DT.95361382  DT.121141234  DT.121140974  DT.100706921  DT.100755472  DT.121141320  DT.75102580  DT.121141492 
    DT.92430336  DT.100059515  DT.121141340  DT.91843983  DT.92051077  DT.427546  DT.95287555 

    Selected AceView cDNA sequences (see all 195):

    BQ233817 BC022827 BQ278683 AW268419 AI378838 BX093425 BM669620 NM_145795 
    AA745747 AI480262 AA347318 BU507565 AI827732 AA741214 CR590888 AA863009 
    BM977057 AI360525 CB118996 AI470167 NM_145794 BQ014551 NM_017613 T95247 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for DONSON (see all 18)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9 ^ 10a · 10b ^ 11a · 11b · 11c ^ 12 ^ 13a · 13b · 13c · 13d · 13e ^ 14a · 14b · 14c ·
    SP1:                                                              -           -                                                                                 
    SP2:                                                              -           -                                   -     -     -     -     -     -     -     -   
    SP3:                    -                                         -                                                                                             
    SP4:                    -                       -                 -                                                                                             
    SP5:                                                                                                                                                            

    ExUns: 14d ^ 15a · 15b · 15c · 15d · 15e ^ 16 ^ 17 ^ 18a · 18b · 18c · 18d ^ 19a · 19b ^ 20 ^ 21 ^ 22 ^ 23a · 23b ^ 24a · 24b ^ 25a · 25b · 25c
    SP1:                                                                                                                                                
    SP2:                                                                                                                                                
    SP3:                                                                                                                                                
    SP4:                                                                                                                                                
    SP5:                                                                                                                    -                           


    ECgene alternative splicing isoforms for DONSON

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    DONSON expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCATTGTGAC
    DONSON Expression
    About this image

    DONSON Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    DONSON Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.436341
        Custom PCR Arrays for DONSON
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    QuantiTect SYBR Green Assays in human, mouse, rat DONSON
    QuantiFast Probe-based Assays in human, mouse, rat DONSON
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DONSON

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for DONSON gene from Selected species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Donson1 , 5 downstream neighbor of SON1, 5 80(n)1
    77.68(a)1
      16 (53.25 cM)5
    603641  NM_021720.11  NP_068366.11 
     916772685 
    chicken
    (Gallus gallus)
    Aves DONSON1 downstream neighbor of SON 68.23(n)
    67.23(a)
      418504  XM_004934521.1  XP_004934578.1 
    lizard
    (Anolis carolinensis)
    Reptilia DONSON6
    downstream neighbor of SON
    69(a)
    1 ↔ 1
    3(142938267-142957611)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.64412 Xenopus laevis transcribed sequence with moderate similarity more 74(n)    BU916689.1 
    rainbow trout
    (Oncorhynchus mykiss)
    Actinopterygii Omy.5032 Oncorhynchus mykiss transcribed sequence with weak more 76.72(n)    BX076370.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG26693
    hd1
    humpty dumpty1 33(a)3
    46.99(n)1
    40.2(a)1
      83A13
    406421  NM_141274.31  NP_649531.11 


    ENSEMBL Gene Tree for DONSON (if available)
    TreeFam Gene Tree for DONSON (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for DONSON gene

    DONSON for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for DONSON
    PGOHUM00000238205


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for DONSON (see all 251)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 21 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1423849061,2
    --25509718(+) CTCCCG/TCTTTT 1 -- us2k10--------
    rs1130142931,2
    F--34950331(+) TGCTAC/TGTGAT 1 -- ut311Minor allele frequency- T:0.50CSA 2
    rs1418468391,2
    --34950353(+) AAGGAA/GGCATA 1 -- ut310--------
    rs1851786241,2
    --34950421(+) GAGTTA/TTCTGA 1 -- ut310--------
    rs1463333141,2
    C--34950422(+) AGTTAC/TCTGAG 1 -- ut310--------
    rs1393809291,2
    --34950424(+) TTATCG/TGAGTT 1 -- ut310--------
    rs1433165141,2
    C--34950441(+) CTTTAA/TATCTA 1 -- ut310--------
    rs1899861531,2
    C--34950566(+) CTTGCT/CAGAAG 1 -- ut311Minor allele frequency- C:0.00EU 1311
    rs1164619211,2
    C,F--34950609(+) CTTTGG/ATGTTC 1 -- ut312Minor allele frequency- A:0.01NA EU 1441
    rs1475215841,2
    C,F--34950699(+) TTGCTC/TCAGAG 2 K E mis11Minor allele frequency- T:0.00NA 4550

    HapMap Linkage Disequilibrium report for DONSON (34931848 - 34961014 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for DONSON:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2723356CNV Deletion23290073
    nsv913724CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing DONSON
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 611428    OMIM disorders: --

    3 diseases for DONSON:    
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    myasthenia gravis    down syndrome    malaria


    DONSON for disorders           About GeneDecksing


    Export disorders for DONSON gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for DONSON gene, integrated from 10 sources (see all 15):
    (articles sorted by number of sources associating them with DONSON)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Criteria for gene identification and features of genome organization: analysis of 6.5 Mb of DNA sequence from human chromosome 21. (PubMed id 10773462)1, 2, 3 Slavov D.... Gardiner K. (Gene 2000)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. An unappreciated role for RNA surveillance. (PubMed id 14759258)1, 2 Hillman R.T.... Brenner S.E. (Genome Biol. 2004)
    5. Organization and conservation of the GART/SON/DONSON locus in mouse and human genomes. (PubMed id 10950926)1, 3 Wynn S.L....Buluwela L. (Genomics 2000)
    6. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    7. Proteomic analysis of the 20S proteasome (PSMA3)-interacting proteins reveals a functional link between the proteasome and mRNA metabolism. (PubMed id 22079093)1 Fedorova O.A....Barlev N.A. (Biochem. Biophys. Res. Commun. 2011)
    8. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    9. A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (Proc. Natl. Acad. Sci. U.S.A. 2008)
    10. Prominent use of distal 5' transcription start sites and discovery of a large number of additional exons in ENCODE regions. (PubMed id 17567994)1 Denoeud F....Reymond A. (Genome Res. 2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
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      Query String
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    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 29980 HGNC: 2993 AceView: CRYZL1andDONSON Ensembl:ENSG00000159147 euGenes: HUgn29980
    ECgene: DONSON H-InvDB: DONSON

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for DONSON Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for DONSON gene:
    Search GeneIP for patents involving DONSON

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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