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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

DOLPP1 Gene

protein-coding   GIFtS: 53
GCID: GC09P131844

Dolichyldiphosphatase 1

(Previous name: dolichyl pyrophosphate phosphatase 1)
  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Dolichyldiphosphatase 11 2
Dolichyl Pyrophosphate Phosphatase 11 2 3
Linked To Surfeit Genes In Fugu Rubripes 21 2
LSFR22 3
EC 3.6.1.433 8
EC 3.6.18

External Ids:    HGNC: 295651   Entrez Gene: 571712   Ensembl: ENSG000001671307   OMIM: 6145165   UniProtKB: Q86YN13   

Export aliases for DOLPP1 gene to outside databases

Previous GC identifers: GC09P123489 GC09P125297 GC09P127219 GC09P128923 GC09P130883 GC09P101450


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for DOLPP1 Gene:
A similar gene has been characterized in mice and encodes dolichyl pyrophosphate (Dol-P-P) phosphatase. This
protein dephosphorylates dolichyl pyrophosphate so that it may be re-utilized as a glycosyl carrier lipid by the
oligosaccharyltransferase multisubunit complex in the ER. Alternative splicing results in multiple transcript
variants and protein isoforms. (provided by RefSeq, Jun 2012)

GeneCards Summary for DOLPP1 Gene: 
DOLPP1 (dolichyldiphosphatase 1) is a protein-coding gene. Diseases associated with DOLPP1 include batten disease, and among its related super-pathways are WNT ligand biogenesis and trafficking and Synthesis of substrates in N-glycan biosythesis. GO annotations related to this gene include dolichyldiphosphatase activity.

UniProtKB/Swiss-Prot: DOPP1_HUMAN, Q86YN1
Function: Required for efficient N-glycosylation. Necessary for maintaining optimal levels of dolichol-linked
oligosaccharides. Hydrolyzes dolichyl pyrophosphate at a very high rate and dolichyl monophosphate at a much
lower rate. Does not act on phosphatidate (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000009.11  NC_018920.2  NT_008470.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the DOLPP1 gene promoter:
         HOXA9B   HOXA9   USF1   Sox5   GATA-2   Meis-1b   YY1   USF-1   c-Myb   Meis-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidDOLPP1 promoter sequence
   Search SABiosciences Chromatin IP Primers for DOLPP1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DOLPP1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9q34.1   Ensembl cytogenetic band:  9q34.11   HGNC cytogenetic band: 9q34.1

DOLPP1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DOLPP1 gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09P131844:  view genomic region     (about GC identifiers)

Start:
131,843,379 bp from pter      End:
131,852,717 bp from pter
Size:
9,339 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: DOPP1_HUMAN, Q86YN1 (See protein sequence)
Recommended Name: Dolichyldiphosphatase 1  
Size: 238 amino acids; 27031 Da
Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein (By similarity)
Sequence caution: Sequence=CAB44348.1; Type=Erroneous gene model prediction;
Secondary accessions: A8K3U8 B0QZG4 Q96GF8 Q9Y3G1
Alternative splicing: 2 isoforms:  Q86YN1-1   Q86YN1-2   

Explore the universe of human proteins at neXtProt for DOLPP1: NX_Q86YN1

Explore proteomics data for DOLPP1 at MOPED 

4 DME Specific Peptides for DOLPP1 (Q86YN1)
 LVSYSRVY  YGMPSSHSQFM  VIQEPRPCGGPH  IVGFVTLIIFKRELHTISFLGGL 

DOLPP1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

DOLPP1 Protein Expression
REFSEQ proteins (2 alternative transcripts): 
NP_001129389.1  NP_065171.2  

ENSEMBL proteins: 
 ENSP00000361625   ENSP00000384043   ENSP00000333294   ENSP00000403278   ENSP00000440218  
Reactome Protein details: Q86YN1
Human Recombinant Protein Products for DOLPP1: 
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Cloud-Clone Corp. Proteins for DOLPP1 

Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005789endoplasmic reticulum membrane TAS--
GO:0016020membrane ----
GO:0030176integral to endoplasmic reticulum membrane ISS--

DOLPP1 for ontologies           About GeneDecksing



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Cloud-Clone Corp. CLIAs for DOLPP1


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section
2 InterPro protein domains:
 IPR000326 P_Acid_Pase_2/haloperoxidase
 IPR016118 P_Acid_Pase/Cl_peroxidase_N

Graphical View of Domain Structure for InterPro Entry Q86YN1

ProtoNet protein and cluster: Q86YN1

1 Blocks protein domain: IPB000326 PA-phosphatase related phosphoesterase

UniProtKB/Swiss-Prot: DOPP1_HUMAN, Q86YN1
Similarity: Belongs to the dolichyldiphosphatase family


DOLPP1 for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
About This Section

Molecular Function:

     UniProtKB/Swiss-Prot Summary: DOPP1_HUMAN, Q86YN1
Function: Required for efficient N-glycosylation. Necessary for maintaining optimal levels of dolichol-linked
oligosaccharides. Hydrolyzes dolichyl pyrophosphate at a very high rate and dolichyl monophosphate at a much
lower rate. Does not act on phosphatidate (By similarity)
Catalytic activity: Dolichyl diphosphate + H(2)O = dolichyl phosphate + phosphate

     Enzyme Numbers (IUBMB): EC 3.6.1.431 2 EC 3.6.12

     Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0003824catalytic activity ----
GO:0047874dolichyldiphosphatase activity ISS--
     
DOLPP1 for ontologies           About GeneDecksing


Phenotypes:
     1 GenomeRNAi human phenotype for DOLPP1:
 Decreased viability of wild-ty 

Animal Models:
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miRNA
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SwitchGear 3'UTR luciferase reporter plasmidDOLPP1 3' UTR sequence
Inhib. RNA
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(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
About This Section

SuperPaths for DOLPP1 About                                                                                                See pathways by source

SuperPathContained pathways About
1Asparagine N-linked glycosylation
Asparagine N-linked glycosylation0.77
N-Glycan biosynthesis0.52
WNT ligand biogenesis and trafficking0.77
Post-translational protein modification0.44
Signaling by Wnt0.62
Metabolism of proteins0.35
2Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein0.53
Synthesis of substrates in N-glycan biosythesis0.53
3Signaling by GPCR
Signal Transduction0.55
4Synthesis of Dolichyl-phosphate
Synthesis of Dolichyl-phosphate

Pathways by source                                                                                                                                                                 See SuperPaths
Show all pathways


5/9        Reactome Pathways for DOLPP1 (see all 9)
    Signaling by Wnt
Asparagine N-linked glycosylation
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
Synthesis of Dolichyl-phosphate
Synthesis of substrates in N-glycan biosythesis


1         Kegg Pathway  (Kegg details for DOLPP1):
    N-Glycan biosynthesis

UniProtKB/Swiss-Prot: DOPP1_HUMAN, Q86YN1
Pathway: Protein modification; protein glycosylation


DOLPP1 for pathways           About GeneDecksing

Interactions:

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for DOLPP1

STRING Interaction Network Preview (showing 5 interactants - click image to see 11)

5/11 Interacting proteins for DOLPP1 (ENSP000003616254) via UniProtKB, MINT, STRING, and/or I2D (see all 11)

InteractantInteraction Details
GeneCardExternal ID(s)
ALG5ENSP000002398914STRING: ENSP00000239891
DOLKENSP000003616674STRING: ENSP00000361667
DPAGT1ENSP000003461424STRING: ENSP00000346142
DPM1ENSP000003606444STRING: ENSP00000360644
DPM2ENSP000003221814STRING: ENSP00000322181
About this table

Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0006487protein N-linked glycosylation ISS--
GO:0006488dolichol-linked oligosaccharide biosynthetic process TAS--
GO:0006489dolichyl diphosphate biosynthetic process TAS--
GO:0018279protein N-linked glycosylation via asparagine TAS--
GO:0043687post-translational protein modification TAS--

DOLPP1 for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section
Browse Small Molecules at EMD Millipore
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for DOLPP1 (DOPP1)

5 HMDB Compounds for DOLPP1    About this table
CompoundSynonyms CAS #PubMed Ids
Dolichol phosphatedolichol-phosphate (see all 6)34457-14-2--
Dolichol-20Dolichol (C100) (see all 5)2067-66-5--
Dolichyl diphosphateDolichyl diphosphate (see all 2)37247-98-6--
PhosphateNFB Orthophosphate (see all 13)14265-44-2--
WaterDihydrogen oxide (see all 2)7732-18-5--

Search CenterWatch for drugs/clinical trials and news about DOLPP1 / DOPP1

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for DOLPP1 gene (2 alternative transcripts): 
NM_001135917.1  NM_020438.4  

Unigene Cluster for DOLPP1:

Dolichyl pyrophosphate phosphatase 1
Hs.21701  [show with all ESTs]
Unigene Representative Sequence: NM_020438
6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000372546(uc004bxc.3 uc004bxd.3 uc004bxe.3) ENST00000406974
ENST00000327812 ENST00000412363 ENST00000480255 ENST00000540102
miRNA
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SwitchGear 3'UTR luciferase reporter plasmidDOLPP1 3' UTR sequence
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  QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DOLPP1

Additional mRNA sequence: 

AK290713.1 AK293627.1 AY189675.1 BC009493.2 BC022553.1 BC033686.1 BC040152.1 BC067858.1 
DQ655991.2 DQ655992.2 NR_072983.1 

7 DOTS entries:

DT.101981457  DT.97814291  DT.100750136  DT.454614  DT.315069  DT.100728568  DT.91743941 

24/144 AceView cDNA sequences (see all 144):

BC022553 BX384141 BM679488 BE383359 BC033686 BQ425191 BM854100 BM721060 
BX093232 BF515606 BQ952757 AW474451 BQ186681 BU624308 BF038648 CA416688 
BC009493 BF981660 AA603748 BM543960 BF941705 BU556808 BM726499 CR597048 

GeneLoc Exon Structure

3 Alternative Splicing Database (ASD) splice patterns (SP) for DOLPP1    About this scheme

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b
SP1:                                                            
SP2:                                      -                     
SP3:                    -                 -                     


ECgene alternative splicing isoforms for DOLPP1

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

DOLPP1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: TTTCCCTCCC
DOLPP1 Expression
About this image


See DOLPP1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for DOLPP1

SOURCE GeneReport for Unigene cluster: Hs.21701
    SABiosciences Custom PCR Arrays for DOLPP1
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In Situ
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(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for DOLPP1 gene from 9/20 species (see all 20)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Dolpp11 , 5 dolichyl pyrophosphate phosphatase 11, 5 90.48(n)1
94.12(a)1
  2 (21.68 cM)5
571701  NM_020329.31  NP_065062.11 
 303922545 
chicken
(Gallus gallus)
Aves DOLPP11 dolichyl pyrophosphate phosphatase 1 78.71(n)
87.82(a)
  417196  NM_001030689.2  NP_001025860.2 
lizard
(Anolis carolinensis)
Reptilia DOLPP16
Uncharacterized protein
80(a)
1 ↔ 1
GL344059.1(65772-80351)
African clawed frog
(Xenopus laevis)
Amphibia Xl.146402 Xenopus laevis transcribed sequence with moderate similarity more 75.97(n)    CA787939.1 
zebrafish
(Danio rerio)
Actinopterygii dolpp11 dolichyl pyrophosphate phosphatase 1 73.14(n)
75.95(a)
  474331  NM_001007061.1  NP_001007062.1 
mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP0026661 AGAP002666-PA 58.56(n)
57.8(a)
  1273294  XM_312258.4  XP_312258.3 
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes CAX4(YGR036C)4
CAX41
Dolichyl pyrophosphate (Dol-P-P) phosphatase with a more4
Cax4p1
44.79(n)1
36.87(a)1
  7(558868-558149)4
8529241, 4  NP_011550.31  NP_011550.14 
thale cress
(Arabidopsis thaliana)
eudicotyledons AT5G030801 dolichyldiphosphatase 45.27(n)
40.47(a)
  831801  NM_120386.3  NP_195928.1 
rice
(Oryza sativa)
Liliopsida Os03g02887001 hypothetical protein 49.6(n)
40.1(a)
  4332492  NM_001056322.1  NP_001049787.1 


ENSEMBL Gene Tree for DOLPP1 (if available)
TreeFam Gene Tree for DOLPP1 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
  --

(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

10/282 SNPs in DOLPP1 are shown (see all 282)    About this table     
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 9 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs1831061081,2
--131841487(+) GGTCTG/TGACCA 3 -- us2k10--------
rs283655661,2
C,H--131841549(+) GGTGGC/TTGTAA 3 -- us2k16Minor allele frequency- T:0.00NS EA NA 422
rs669702251,2
C--131841691(+) TGAAT-/GCTGAG 3 -- us2k10--------
rs1864319611,2
--131841853(+) GGGCCA/GGGCAA 3 -- us2k10--------
rs108194611,2
C,F,A,H--131841887(+) TCCCAT/CGCAGC 3 -- us2k118Minor allele frequency- C:0.20NS EA NA WA CSA 796
rs600369331,2
C,F--131842024(+) CTCTAC/TGAAAA 3 -- us2k11Minor allele frequency- T:0.03WA 118
rs1899862981,2
--131842025(+) TCTACA/GAAAAG 3 -- us2k10--------
rs342541041,2
C--131842094(+) TCTCA-/A/AA  
        
AAAAA
3 -- us2k11NA 2
rs1410333441,2
C--131842127(+) ATGGCA/GGCTCA 3 -- us2k10--------
rs1822627991,2
--131842129(+) GGCGGC/GTCACG 3 -- us2k10--------

HapMap Linkage Disequilibrium report for DOLPP1 (131843379 - 131852717 bp)

Structural Variations
     Database of Genomic Variants (DGV) 4 variations for DOLPP1:    About this table     
Variant IDTypeSubtypePubMed ID
nsv509323CNV Insertion20534489
nsv831729CNV Loss17160897
nsv818725CNV Gain17921354
nsv893902CNV Gain21882294

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section
OMIM gene information: 614516    OMIM disorders: --

2 diseases for DOLPP1:    About MalaCards
batten disease    

1 disease from the University of Copenhagen DISEASES database for DOLPP1:
Batten disease

DOLPP1 for disorders           About GeneDecksing


Export disorders for DOLPP1 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
About This Section

PubMed articles for DOLPP1 gene integrated from 9 sources:
(articles sorted by number of sources associating them with DOLPP1)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Extensive gene order differences within regions of conserved synteny between the Fugu and human genomes: implications for chromosomal evolution and the cloning of disease genes. (PubMed id 10369878)1, 2, 3 Gilley J. and Fried M. (1999)
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
  3. DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)1, 2 Humphray S.J.... Dunham I. (2004)
  4. Identification and characterization of a cDNA encodin g a dolichyl pyrophosphate phosphatase located in the endoplasmic reticulum of mammalian cells. (PubMed id 12198133)1, 3 Rush J.S....Waechter C.J. (2002)
  5. Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (2009)
  6. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
  7. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
  8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
  9. Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )2 Aoki H.... Hino O. (2000)
  10. Enzymatic activities in cultured human lymphocytes th at dephosphorylate dolichyl pyrophosphate and dolichyl phosphate. (PubMed id 6243292)1 Wedgwood J.F. and Strominger J.L. (1980)

(in PubMed, OMIM, and NCBI Bookshelf)
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section
Entrez Gene: 57171 HGNC: 29565 AceView: DOLPP1 Ensembl:ENSG00000167130 euGenes: HUgn57171
ECgene: DOLPP1 Kegg: 57171 H-InvDB: DOLPP1

(According to HUGE)
About This Section
  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
NameDescription
PharmGKB entry for DOLPP1 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
About This Section
Patent Information for DOLPP1 gene:
Search GeneIP for patents involving DOLPP1

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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