Aliases for DOK4 Gene
External Ids for DOK4 Gene
GeneCards Summary for DOK4 Gene
DOK4 (Docking Protein 4) is a Protein Coding gene. Among its related pathways are GDNF-Family Ligands and Receptor Interactions and Signaling events regulated by Ret tyrosine kinase. GO annotations related to this gene include phospholipid binding and insulin receptor binding. An important paralog of this gene is DOK1.
UniProtKB/Swiss-Prot for DOK4 Gene
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK4 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway (By similarity). Putative link with downstream effectors of RET in neuronal differentiation. May be involved in the regulation of the immune response induced by T-cells.