DOK3 Gene
protein-coding GIFtS: 51
GCID: GC05M176928
|
|
docking protein 3
| |
Aliases
for DOK3 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Docking Protein 31 2 | | Downstream Of Tyrosine Kinase 32 3 | | DOKL2 5 | | FLJ225701 | | Dok-Like Protein2 |
Export aliases for DOK3 gene to outside databasesPrevious GC identifers: GC00U916977 GC05M176861 GC05M171849 |
Summaries
for DOK3 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: DOK3_HUMAN, Q7L591Function: DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for theassembly of multimolecular signaling complexes. DOK3 is a negative regulator of JNK signaling in B-cells throughinteraction with INPP5D/SHIP1. May modulate ABL1 function (By similarity)
Gene Wiki entry for DOK3
|
Genomic Views
for DOK3 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000005.9 NC_018916.1 NT_023133.13
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the DOK3 gene promoter:
E2F AP-1 STAT3 IRF-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for DOK3
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DOK3 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 5q35.3 Ensembl cytogenetic band: 5q35.3 HGNC cytogenetic band: 5q35DOK3 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 5 GeneLoc Exon Structure GeneLoc location for GC05M176928: view genomic region
(about GC identifiers)
Start:
|
176,928,905 bp from pter |
End:
|
176,938,275 bp from pter |
Size:
|
9,371 bases |
Orientation:
|
minus strand |
|
Proteins
for DOK3 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: DOK3_HUMAN, Q7L591 (See
protein sequence)Recommended Name: Docking protein 3 Size: 496 amino acids; 53288 Da
Subunit: On tyrosine phosphorylation, interacts with CSK and INPP5D/SHIP1 via their SH2 domains. Both Tyr-381 andTyr-398 are required for interaction with INPP5D. Only Tyr-381 is required for interaction with CSK. Binds ABL1through the PTB domain and in a kinase-dependent manner. Does not interact with RasGAP (By similarity)
Subcellular location: Cytoplasm (By similarity). Cell membrane; Peripheral membrane protein; Cytoplasmic side (Bysimilarity)
Secondary accessions: Q8N864 Q9BQB3 Q9H666Alternative splicing: 4 isoforms: Q7L591-1 Q7L591-2 Q7L591-3 Q7L591-4 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for DOK3: NX_Q7L591
Post-translational modifications:
Constitutively tyrosine-phosphorylated (By similarity)1
On IL2 stimulation, phosphorylated on C-terminal tyrosine residues possibly by Src kinases. Can also be phosphorylatedby ABL1 kinase (By similarity)1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q7L591
DOK3 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_001138347.1 NP_001138348.1 NP_079148.2
ENSEMBL proteins: ENSP00000325174 ENSP00000366316 ENSP00000349727 ENSP00000421688 ENSP00000422395 ENSP00000423328 ENSP00000423635 ENSP00000424726 ENSP00000424580 ENSP00000426694
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
DOK3 for ontologies About GeneDecksing
DOK3 Antibody Products:
Assay Products for DOK3: |
Protein
Domains /
Families
for DOK3 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
DOK3 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q7L591ProtoNet protein and cluster: Q7L591 1 Blocks protein family: IPB001849 Pleckstrin-like
UniProtKB/Swiss-Prot: DOK3_HUMAN, Q7L591Domain: PTB domain mediates receptor interaction (By similarity)Similarity: Belongs to the DOK family. Type A subfamilySimilarity: Contains 1 IRS-type PTB domainSimilarity: Contains 1 PH domain |
Function
for DOK3 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: DOK3_HUMAN, Q7L591Function: DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for theassembly of multimolecular signaling complexes. DOK3 is a negative regulator of JNK signaling in B-cells throughinteraction with INPP5D/SHIP1. May modulate ABL1 function (By similarity)
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DOK3 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DOK3 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): DOK3 (NM_024872) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for DOK3 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DOK3 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DOK3 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
DOK3 for ontologies About GeneDecksing
Animal Models:
Mouse knock-out Dok3tm1Ppp for DOK3
5 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Dok3):
DOK3 for phenotypes About GeneDecksing
|
Pathways & Interactions
for DOK3 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | B Cell Receptor Signaling Pathway | |
1  BioSystems Pathway for DOK3
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for DOK3
STRING Interaction
Network Preview (showing 5 interactants - click image to see 10)
5/16 Interacting proteins for DOK3 (Q7L5912, 3 ENSP000003497274) via UniProtKB, MINT, STRING, and/or I2D (see all 16)About this table
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0007265 | Ras protein signal transduction |
IEA | -- |
DOK3 for ontologies About GeneDecksing
|
Drugs & Compounds
for DOK3 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for DOK3
Search CenterWatch for drugs/clinical trials and news about DOK3
|
Transcripts
for DOK3 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for DOK3 gene (3 alternative transcripts): NM_001144875.1 NM_001144876.1 NM_024872.2 Unigene Cluster for DOK3: Docking protein 3 Hs.720849 [show with all ESTs]Unigene Representative Sequence: BC00486713 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000312943(uc003mhi.4 uc003mhj.4) ENST00000500323(uc003mhh.4)
ENST00000377112 ENST00000357198(uc003mhk.3) ENST00000501403 ENST00000510380
ENST00000506493 ENST00000502885 ENST00000510898 ENST00000509310 ENST00000502380
ENST00000512660 ENST00000510389
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DOK3 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DOK3 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 3): DOK3 (NM_024872) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for DOK3 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DOK3 |
Additional cDNA sequence: AK026223.1 AK097258.1 AK307300.1 AL833678.1 BC004564.2 BC004867.2 13 DOTS entries: DT.65286148 DT.207179 DT.100816137 DT.86844545 DT.120862448 DT.92426270 DT.101976334 DT.120862388 DT.120862369 DT.120862371 DT.120862381 DT.120862416 DT.65287309 24/120 AceView cDNA sequences (see all 120): CR595723 BM479812 AA765866 BF795410 CD367823 BQ030365 BG756981 AI359621 BF477398 AI190123 BG756254 BX364341 BQ061336 AI760602 BG758338 BM150409 BM454399 CF138674 AW505181 AA812168 BI489608 BQ061745 BI910171 AL833678
GeneLoc Exon Structure
5/13 Alternative Splicing Database (ASD) splice patterns (SP) for DOK3 (see all 13) About this scheme
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | · | 2c | · | 2d | ^ | 3a | · | 3b | · | 3c | · | 3d | · | 3e | ^ | 4a | · | 4b | · | 4c | ^ | 5a | · | 5b | ^ | 6 | ^ | 7a | · | 7b | ^ | 8a | · | 8b |
|---|
|
| SP1: | | | - | | - | | - | | - | | - | | - | | - | | | | - | | - | | - | | | | | | | | | | | | - | | - | | | | | | |
| SP2: | | | - | | - | | - | | - | | - | | | | | | | | - | | - | | - | | | | | | | | | | | | - | | - | | | | | | |
| SP3: | | | | | | | | | | | - | | | | | | | | - | | - | | - | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | - | | - | | - | | - | | - | | | | | | | | - | | - | | - | | - | | - | | | | | | | | - | | - | | | | | | |
| SP5: | | | | | | | | | | | - | | - | | - | | | | - | | - | | - | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for DOK3
|
Expression
for DOK3 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| DOK3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See DOK3 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for DOK3
SOURCE GeneReport for Unigene cluster: Hs.720849
UniProtKB/Swiss-Prot: DOK3_HUMAN, Q7L591Tissue specificity: Expressed in spleen
SABiosciences Expression via Pathway-Focused PCR Array including DOK3:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DOK3
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat DOK3 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DOK3 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DOK3 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DOK3 |
Orthologs
for DOK3 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for DOK3 gene from 5/13 species (see all 13) About this table
ENSEMBL Gene Tree for DOK3 (if available)
TreeFam Gene Tree for DOK3 (if available) |
Paralogs
for DOK3 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for DOK3 gene
- DOK12 DOK22
3 SIMAP similar genes for DOK3 using alignment to 10 protein entries: DOK3_HUMAN (see all proteins):FRS2 DOK1 DOK2
DOK3 for paralogs About GeneDecksing
|
Genomic Variants
for DOK3 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 5 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for DOK3 (176928905 - 176938275 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for DOK3: -- | SABiosciences Cancer Mutation PCR Assays |
|
Disorders
/ Diseases
for DOK3 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
DOK3 for disorders About GeneDecksing
OMIM gene information: 611435
OMIM disorders: --
1  disease for DOK3: About MalaCardsneuronitis
Export disorders for DOK3 gene to outside databases
|
Publications
for DOK3 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for DOK3 gene, integrated from 9 sources (see all 18):
(articles sorted by number of sources associating them with DOK3) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- DOK4 and DOK5: new Dok-related genes expressed in human T cells. (PubMed id 12595900)1, 2, 3 Favre C....Nunes J.A. (2003)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Dok-3, a novel adapter molecule involved in the negative regulation of immunoreceptor signaling. (PubMed id 10733577)1, 3 Lemay S....Veillette A. (2000)
- Proteomic analysis of integrin alphaIIbbeta3 outside- in signaling reveals Src-kinase-independent phosphorylation of Dok-1 and Dok-3 leading to SHIP-1 interactions. (PubMed id 19682241)1, 9 Senis Y.A....GarcA-a A. (2009)
- DOK3 negatively regulates LPS responses and endotoxin tolerance. (PubMed id 22761938)1 Peng Q....Humphrey M.B. (2012)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- The B-cell antigen receptor signals through a preform ed transducer module of SLP65 and CIN85. (PubMed id 21822214)1 Oellerich T....Wienands J. (2011)
- The proximal signaling network of the BCR-ABL1 oncoge ne shows a modular organization. (PubMed id 20697350)1 Titz B....Graeber T.G. (2010)
- Identification of DOK genes as lung tumor suppressors . (PubMed id 20139980)1 Berger A.H....Pandolfi P.P. (2010)
|
External Searches for DOK3 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing DOK3 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing DOK3 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing DOK3 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for DOK3 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for DOK3 gene:
Search GeneIP for patents involving DOK3
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for DOK3 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for DOK3 | | OriGene shRNA RFP for DOK3 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DOK3 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DOK3 | | | OriGene Protein Over-expression Lysate for DOK3 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for DOK3 | | OriGene 3'-UTR Clone for DOK3 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DOK3 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DOK3 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for DOK3 | | OriGene Custom Protein Services for DOK3 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat DOK3 | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DOK3 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DOK3 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DOK3 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DOK3 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DOK3 |
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| | | | Search Tocris compounds for DOK3 |
| |  |  |  |  | | | | |
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 |
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 | | | DOK3 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DOK3 |
|  |  |  | | | | ThermoFisher Antibodies for DOK3 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DOK3 |
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