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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

DOHH Gene

protein-coding   GIFtS: 51
GCID: GC19M003443

deoxyhypusine hydroxylase/monooxygenase

(Previous name: HEAT-like (PBS lyase) repeat containing 1 )
(Previous symbol: HLRC1)
 Explore 1 disease affiliated with
DOHH via our new
 Human Malady Compendium 
Biological research products
for DOHH
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Deoxyhypusine Hydroxylase/Monooxygenase1 2     HDOHH1
HLRC11 2 3     HEAT-Like Repeat-Containing Protein 12 3
HEAT-Like (PBS Lyase) Repeat Containing 11 2     EC 1.14.99.293 8
Deoxyhypusine Dioxygenase2 3     MGC42931
Deoxyhypusine Monooxygenase2 3     Deoxyhypusine Hydroxylase2

External Ids:    HGNC: 286621   Entrez Gene: 834752   Ensembl: ENSG000001299327   OMIM: 6112625   UniProtKB: Q9BU893   

Export aliases for DOHH gene to outside databases

Previous GC identifer: GC19M003256


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for DOHH:
This gene encodes a metalloenzyme that catalyzes the last step in the conversion of lysine to the unique amino acid
hypusine in eukaryotic initiation factor 5A. The encoded protein hydroxylates deoxyhypusine to form hypusine in the
mature eukaryotic initiation factor 5A protein. Alternative splicing results in multiple transcript variants.(provided
by RefSeq, Feb 2009)

UniProtKB/Swiss-Prot: DOHH_HUMAN, Q9BU89
Function: Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential
post-translational modification only found in mature eIF-5A factor




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000019.9  NC_018930.1  NT_011255.14  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the DOHH gene promoter:
         AhR   NRF-2   AP-2gamma   ATF6   Arnt   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidDOHH promoter sequence
   Search SABiosciences Chromatin IP Primers for DOHH

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DOHH


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19p13.3   Ensembl cytogenetic band:  19p13.3   HGNC cytogenetic band: 19p13.3

DOHH Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DOHH gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19M003443:  view genomic region     (about GC identifiers)

Start:
3,490,819 bp from pter      End:
3,500,938 bp from pter
Size:
10,120 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: DOHH_HUMAN, Q9BU89 (See protein sequence)
Recommended Name: Deoxyhypusine hydroxylase  
Size: 302 amino acids; 32904 Da
Cofactor: Binds 2 Fe(2+) ions per subunit
Secondary accessions: O75265

Explore the universe of human proteins at neXtProt for DOHH: NX_Q9BU89

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9BU89

  • 4/8 DME Specific Peptides for DOHH (Q9BU89) (see all 8)
     SALLKHE  SVDPAPP  ESCEVALDM  RYRAMFALR 

    DOHH Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_001138637.1  NP_112594.1  

    ENSEMBL proteins: 
     ENSP00000250937   ENSP00000464905   ENSP00000468416   ENSP00000398882  
    Reactome Protein details: Q9BU89
    Human Recombinant Protein Products: 
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    Uscn Proteins for DOHH

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005575cellular_component ND--
    GO:0005829cytosol TAS--


    DOHH for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    DOHH for domains           About GeneDecksing

    4 InterPro domains/families:
     IPR011989 ARM-like
     IPR021133 HEAT_type_2
     IPR004155 PBS_lyase_HEAT
     IPR016024 ARM-type_fold

    Graphical View of Domain Structure for InterPro Entry Q9BU89

    ProtoNet protein and cluster: Q9BU89

    1 Blocks protein family: IPB004155 PBS lyase HEAT-like repeat

    UniProtKB/Swiss-Prot: DOHH_HUMAN, Q9BU89
    Similarity: Belongs to the deoxyhypusine hydroxylase family
    Similarity: Contains 5 HEAT-like PBS-type repeats


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: DOHH_HUMAN, Q9BU89
    Function: Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential
    post-translational modification only found in mature eIF-5A factor
    Catalytic activity: Protein N(6)-(4-aminobutyl)-L-lysine + AH(2) + O(2) = protein
    N(6)-((R)-4-amino-2-hydroxybutyl)-L-lysine + A + H(2)O

    Enzyme Number (IUBMB): EC 1.14.99.291 2

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    3 QIAGEN miScript miRNA Assays for microRNAs that regulate DOHH:
    hsa-miR-889 hsa-miR-331-3p hsa-miR-32*
    SwitchGear 3'UTR luciferase reporter plasmidDOHH 3' UTR sequence
    Inhib. RNA
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    Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI17213197
    GO:0019135deoxyhypusine monooxygenase activity TAS--
    GO:0046872metal ion binding IEA--


    DOHH for ontologies           About GeneDecksing



    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1hypusine biosynthesis
    hypusine biosynthesis1.00
    Hypusine synthesis from eIF5A-lysine0.50
    2Asparagine N-linked glycosylation
    Post-translational protein modification0.44
    Metabolism of proteins0.15
    3PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
    PTM: gamma carboxylation, hypusine formation and arylsulfatase activation1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    1 BioSystems Pathway for DOHH 
        hypusine biosynthesis

    4        Reactome Pathways for DOHH
        Hypusine synthesis from eIF5A-lysine
    Metabolism of proteins
    Post-translational protein modification
    PTM: gamma carboxylation, hypusine formation and arylsulfatase activation


    UniProtKB/Swiss-Prot: DOHH_HUMAN, Q9BU89
    Pathway: Protein modification; eIF5A hypusination


    DOHH for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for DOHH

    STRING Interaction Network Preview (showing 5 interactants - click image to see 14)

    5/77 Interacting proteins for DOHH (Q9BU893 ENSP000002509374) via UniProtKB, MINT, STRING, and/or I2D (see all 77)

    InteractantInteraction Details
    GeneCardExternal ID(s)
    CCT2P783713, ENSP000002993004I2D: score=4 STRING: ENSP00000299300
    EIF5AP632413, ENSP000003367024I2D: score=3 STRING: ENSP00000336702
    ADAP008133, ENSP000003619654I2D: score=1 STRING: ENSP00000361965
    CCT6AP402273, ENSP000002756034I2D: score=1 STRING: ENSP00000275603
    ENSG00000266442O431963I2D: score=1 
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008612peptidyl-lysine modification to hypusine TAS--
    GO:0043687post-translational protein modification TAS--
    GO:0044267cellular protein metabolic process TAS--


    DOHH for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for DOHH

    3 HMDB Compounds for DOHH    About this table
    CompoundSynonyms CAS #PubMed Ids
    DeoxyhypusineN(6)-(4-Aminobutyl)lysine (see all 2)82543-85-9--
    OxygenOxygen (see all 5)7782-44-7--
    WaterDihydrogen oxide (see all 2)7732-18-5--
    Search CenterWatch for drugs/clinical trials and news about DOHH 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for DOHH gene (2 alternative transcripts): 
    NM_001145165.1  NM_031304.4  

    Unigene Cluster for DOHH:

    Deoxyhypusine hydroxylase/monooxygenase
    Hs.515064  [show with all ESTs]
    Unigene Representative Sequence: NM_001145165
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000250937(uc002lxs.3) ENST00000586906 ENST00000592858 ENST00000587122
    ENST00000427575(uc010xhl.2)

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      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DOHH

    Additional cDNA sequence: 

    BC002817.2 BC009863.2 

    5 DOTS entries:

    DT.211662  DT.97858688  DT.100775787  DT.91760652  DT.95269652 

    24/105 AceView cDNA sequences (see all 105):

    AW135672 BU624567 AW002050 BG491509 AI937482 AW006196 AW340212 AI128417 
    BM559040 AI479685 CF141889 BU147125 BM558865 BF434395 CA774553 AA291261 
    BF509705 AA834578 AA422159 BI549492 BE795251 AI659111 BX375047 AI470153 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for DOHH    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5a · 5b
    SP1:                          -                                 
    SP2:              -           -                                 
    SP3:                                                            


    ECgene alternative splicing isoforms for DOHH

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    DOHH expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TATGAGCACG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See DOHH Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for DOHH

    SOURCE GeneReport for Unigene cluster: Hs.515064
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for DOHH gene from 9/35 species (see all 35)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Dohh1 , 5 deoxyhypusine hydroxylase/monooxygenase1, 5 80.62(n)1
    85.05(a)1
      10 (39.72 cM)5
    1021151  NM_133964.21  NP_598725.21 
     813844285 
    chicken
    (Gallus gallus)
    Aves DOHH1 deoxyhypusine hydroxylase/monooxygenase 74.61(n)
    75.17(a)
      427066  NM_001031413.1  NP_001026584.1 
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.80132 Xenopus laevis transcribed sequence with moderate similarity more 74.85(n)    CA972864.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufb33c042 wufb33c04 73.51(n)   321732  BC046086.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta nero1 CG2245-PA 61.62(n)
    59.26(a)
      43740  NM_143630.1  NP_651887.1 
    worm
    (Caenorhabditis elegans)
    Secernentea dohh-11 Protein DOHH-1 55.44(n)
    58.33(a)
      3565578  NM_063878.2  NP_496279.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes LIA1(YJR070C)4
    LIA11
    Deoxyhypusine hydroxylase, a HEAT-repeat containing more4
    Lia1p1
    50.74(n)1
    52.21(a)1
      10(570598-569621)4
    8535341, 4  NP_012604.11, 4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT3G581801 deoxyhypusine hydroxylase 50.78(n)
    53.05(a)
      824987  NM_115680.2  NP_567062.1 
    rice
    (Oryza sativa)
    Liliopsida Os12g06261001 hypothetical protein 52.23(n)
    51.99(a)
      4352843  NM_001073854.1  NP_001067322.2 


    ENSEMBL Gene Tree for DOHH (if available)
    TreeFam Gene Tree for DOHH (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/226 NCBI SNPs in DOHH are shown (see all 226    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs2009572351,2
    C--3490321(-) GGAGGA/CAAAAC 2 -- ds50010--------
    rs1846751971,2
    --3490454(+) GAGCCA/GGCGGA 2 -- ds50010--------
    rs1898949091,2
    --3490595(+) GAGCTA/GGCTGG 2 -- ds50010--------
    rs1140917181,2
    F,--3490696(+) AGCCAA/GTGGCT 2 -- ds50011Minor allele frequency- G:0.10WA 118
    rs609826351,2
    C,F,--3490743(+) CTCTCG/CGGGAA 2 -- ds50013Minor allele frequency- C:0.32WA 122
    rs1158870011,2
    F,--3490749(+) GGGAAC/TGTTCC 2 -- ds50011Minor allele frequency- T:0.09WA 118
    rs1467597261,2
    --3490798(+) TCACCC/TAACAC 2 -- ds50010--------
    rs10518031,2
    C,F,H,--3490908(+) CCCACT/CCAGGG 2 -- ut31 ese322Minor allele frequency- C:0.43EA MN NS NA WA 4026
    rs1807338861,2
    --3490939(+) CAGGCC/TTCGGG 2 -- ut310--------
    rs22864401,2
    C,F,H,--3490951(+) TGGGGG/AAGTCA 2 -- ut31 ese315Minor allele frequency- A:0.12EA NS WA 3508

    HapMap Linkage Disequilibrium report for DOHH (3490819 - 3500938 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 3 variations for DOHH
         3 CNVs: 30067 30069 30068

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    DOHH for disorders           About GeneDecksing

    OMIM gene information: 611262    OMIM disorders: --

    1 disease for DOHH:    About MalaCards
    malaria


    Export disorders for DOHH gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for DOHH gene, integrated from 9 sources (see all 14):
    (articles sorted by number of sources associating them with DOHH)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Deoxyhypusine hydroxylase is an Fe(II)-dependent, HEAT-repeat enzyme. Identification of amino acid residues critical for Fe(II) binding and catalysis. (PubMed id 16533814)1, 2, 3 Kim Y.S.... Park M.H. (2006)
    2. Molecular cloning, expression, and structural prediction of deoxyhypusine hydroxylase: a HEAT-repeat-containing metalloenzyme. (PubMed id 16371467)1, 2, 3 Park J.-H.... Park M.H. (2006)
    3. Human deoxyhypusine hydroxylase, an enzyme involved i n regulating cell growth, activates O2 with a nonheme diiron center. (PubMed id 19706422)1, 2 Vu V.V....Que L. (2009)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)1, 2 Grimwood J.... Lucas S.M. (2004)
    6. Global landscape of HIV-human protein complexes. (PubMed id 22190034)1 Jager S....Krogan N.J. (2012)
    7. Expression of eukaryotic initiation factor 5A and hypu sine forming enzymes in glioblastoma patient samples: implications for new targe ted therapies. (PubMed id 22927971)1 Preukschas M....Balabanov S. (2012)
    8. Regulation of expression of deoxyhypusine hydroxylase (DOHH), the enzyme that catalyzes the activation of eIF5A, by miR-331-3p and miR -642-5p in prostate cancer cells. (PubMed id 22908221)1 Epis M.R....Leedman P.J. (2012)
    9. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    10. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 83475 HGNC: 28662 AceView: MGC4293 Ensembl:ENSG00000129932 euGenes: HUgn83475
    ECgene: DOHH H-InvDB: DOHH

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for DOHH Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for DOHH gene:
    Search GeneIP for patents involving DOHH

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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