External Ids for DOCK5 Gene
Previous GeneCards Identifiers for DOCK5 Gene
GeneCards Summary for DOCK5 Gene
DOCK5 (Dedicator Of Cytokinesis 5) is a Protein Coding gene. Among its related pathways are Platelet activation, signaling and aggregation and Factors involved in megakaryocyte development and platelet production. GO annotations related to this gene include binding and guanyl-nucleotide exchange factor activity. An important paralog of this gene is DOCK1.
UniProtKB/Swiss-Prot for DOCK5 Gene
Guanine nucleotide exchange factor (GEF) for Rho and Rac. GEF proteins activate small GTPases by exchanging bound GDP for free GTP (By similarity). Along with DOCK1, mediates CRK/CRKL regulation of epithelial and endothelial cell spreading and migration on type IV collagen (PubMed:19004829).