DOCK3 Gene
protein-coding GIFtS: 62
GCID: GC03P050712
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|
dedicator of cytokinesis 3(Previous name: dedicator of cyto-kinesis 3 )
| |
Aliases
for DOCK3 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Dedicator Of Cytokinesis 31 2 | | Modifier Of Cell Adhesion2 3 | | MOCA1 2 3 | | Presenilin-Binding Protein2 3 | | PBP1 2 3 | | Dedicator Of Cyto-Kinesis 31 | | KIAA02991 3 | | Dedicator Of Cytokinesis Protein 32 |
Export aliases for DOCK3 gene to outside databasesPrevious GC identifers: GC03P050193 GC03M050491 GC03P050670 GC03P050671 GC03P050687 |
Summaries
for DOCK3 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for DOCK3:
This gene is specifically expressed in the central nervous system (CNS). It encodes a member of the DOCK (dedicator ofcytokinesis) family of guanine nucleotide exchange factors (GEFs). This protein, dedicator of cytokinesis 3 (DOCK3),is also known as modifier of cell adhesion (MOCA) and presenilin-binding protein (PBP). The DOCK3 and DOCK1, -2 and -4share several conserved amino acids in their DHR-2 (DOCK homology region 2) domains that are required for GEFactivity, and bind directly to WAVE proteins (Wiskott-Aldrich syndrome protein (WASP) family Verprolin-homologousproteins) via their DHR-1 domains. The DOCK3 induces axonal outgrowth in CNS by stimulating membrane recruitment ofthe WAVE complex and activating the small G protein Rac1. This gene is associated with an attention deficithyperactivity disorder-like phenotype by a complex chromosomal rearrangement. (provided by RefSeq, Aug 2010)
UniProtKB/Swiss-Prot: DOCK3_HUMAN, Q8IZD9Function: Potential guanine nucleotide exchange factor (GEF). GEF proteins activate some small GTPases by exchangingbound GDP for free GTP. Its interaction with presenilin proteins as well as its ability to stimulate Tau/MAPTphosphorylation suggest that it may be involved in Alzheimer disease. Ectopic expression in nerve cells decreases thesecretion of beta-amyloid APBA1 protein and lowers the rate of cell-substratum adhesion, suggesting that it may affectthe function of some small GTPase involved in the regulation of actin cytoskeleton or cell adhesion receptors (Bysimilarity)
Gene Wiki entry for DOCK3 (Dock3)
|
Genomic Views
for DOCK3 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000003.11 NC_018914.1 NT_022517.18
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the DOCK3 gene promoter:
c-Fos AP-1 ATF-2 Nkx2-5 C/EBPalpha GATA-1 AREB6 c-Jun
Other transcription factors
Search SABiosciences Chromatin IP Primers for DOCK3
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DOCK3 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 3p21.2 Ensembl cytogenetic band: 3p21.2 HGNC cytogenetic band: 3p21DOCK3 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 3 GeneLoc Exon Structure GeneLoc location for GC03P050712: view genomic region
(about GC identifiers)
Start:
|
50,712,672 bp from pter |
End:
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51,421,629 bp from pter |
Size:
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708,958 bases |
Orientation:
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plus strand |
1 alternative location:
| Chr3+,PATCHES 51,415,843-51,419,921 |
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Proteins
for DOCK3 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: DOCK3_HUMAN, Q8IZD9 (See
protein sequence)Recommended Name: Dedicator of cytokinesis protein 3 Size: 2030 amino acids; 233103 Da
Subunit: Interacts with presenilin proteins PSEN1 and PSEN2. Interacts with CRK (By similarity)
Subcellular location: Cytoplasm (By similarity)
Secondary accessions: O15017Explore the universe of human proteins at neXtProt for DOCK3: NX_Q8IZD9
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8IZD9
DOCK3 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_004938.1
ENSEMBL proteins: ENSP00000266037 Reactome Protein details: Q8IZD9
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
DOCK3 for ontologies About GeneDecksing
DOCK3 Antibody Products:
Assay Products for DOCK3: |
Protein
Domains /
Families
for DOCK3 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
DOCK3 for domains About GeneDecksing
5/6 InterPro domains/families (see all 6):Graphical View of Domain Structure for InterPro Entry Q8IZD9ProtoNet protein and cluster: Q8IZD9 1 Blocks protein family: IPB010703 Dedicator of cytokinesis
UniProtKB/Swiss-Prot: DOCK3_HUMAN, Q8IZD9Domain: The DHR-2 domain may mediate some GEF activity (By similarity)Similarity: Belongs to the DOCK familySimilarity: Contains 1 DHR-1 domainSimilarity: Contains 1 DHR-2 domainSimilarity: Contains 1 SH3 domain |
Function
for DOCK3 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: DOCK3_HUMAN, Q8IZD9Function: Potential guanine nucleotide exchange factor (GEF). GEF proteins activate some small GTPases by exchangingbound GDP for free GTP. Its interaction with presenilin proteins as well as its ability to stimulate Tau/MAPTphosphorylation suggest that it may be involved in Alzheimer disease. Ectopic expression in nerve cells decreases thesecretion of beta-amyloid APBA1 protein and lowers the rate of cell-substratum adhesion, suggesting that it may affectthe function of some small GTPase involved in the regulation of actin cytoskeleton or cell adhesion receptors (Bysimilarity)
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DOCK3 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DOCK3
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: DOCK3 (NM_004947) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for DOCK3 | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat DOCK3 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DOCK3 |
Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view): About this table
DOCK3 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for DOCK3:
Animal Models:
4 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Dock3):
DOCK3 for phenotypes About GeneDecksing
|
Pathways & Interactions
for DOCK3 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Presenilin-Mediated Signaling | | | 2 | Factors involved in megakaryocyte development and platelet production | | | 3 | Platelet activation, signaling and aggregation | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for DOCK3
2 
Reactome Pathways for DOCK3
DOCK3 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for DOCK3
STRING Interaction
Network Preview (showing 5 interactants - click image to see 11)
5/15 Interacting proteins for DOCK3 (Q8IZD91, 2, 3 ENSP000002660374) via UniProtKB, MINT, STRING, and/or I2D (see all 15)About this table
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0007264 | small GTPase mediated signal transduction |
IEA | -- |
DOCK3 for ontologies About GeneDecksing
|
Drugs & Compounds
for DOCK3 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for DOCK3
3 HMDB Compounds for DOCK3 About this table
Search CenterWatch for drugs/clinical trials and news about DOCK3
|
Transcripts
for DOCK3 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for DOCK3 gene: NM_004947.4 Unigene Cluster for DOCK3: Dedicator of cytokinesis 3 Hs.476284 [show with all ESTs]Unigene Representative Sequence: NM_0049471 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000266037(uc011bds.2)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DOCK3 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DOCK3
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: DOCK3 (NM_004947) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for DOCK3 | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat DOCK3 |
Additional cDNA sequence: AB002297.1 AK310984.1 AY145303.1 AY254099.1 BC037933.2 BC045793.1 BC131746.1 4 DOTS entries: DT.115136 DT.91674739 DT.95369327 DT.120853303 19 AceView cDNA sequences: AI124838 AW899395 CD675268 BF959647 BU178856 BF963323 T05544 BF954324 BM728787 BU742704 BE700244 AI808258 AY145303 AW893434 BF959528 NM_004947 AY254099 AB002297 BF951489
GeneLoc Exon Structure
|
Expression
for DOCK3 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| DOCK3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTCAAAATCC
About this image
See DOCK3 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for DOCK3
SOURCE GeneReport for Unigene cluster: Hs.476284
UniProtKB/Swiss-Prot: DOCK3_HUMAN, Q8IZD9Tissue specificity: In normal brains, it is localized in the neuropil, and occasionally in the pyramidal cells, whilein Alzheimer disease brains, it is associated with neurofibrillary tangles
SABiosciences Custom PCR Arrays for DOCK3
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DOCK3
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat DOCK3 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DOCK3 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DOCK3 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DOCK3 |
Orthologs
for DOCK3 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for DOCK3 gene from 5/21 species (see all 21) About this table
ENSEMBL Gene Tree for DOCK3 (if available)
TreeFam Gene Tree for DOCK3 (if available) |
Paralogs
for DOCK3 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for DOCK3 gene
- DOCK42 DOCK12 DOCK22 DOCK52
5 SIMAP similar genes for DOCK3 using alignment to 3 protein entries: DOCK3_HUMAN (see all proteins):DOCK4 DOCK2 DKFZp779M164 DOCK1 DOCK5
DOCK3 for paralogs About GeneDecksing
|
Genomic Variants
for DOCK3 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 3 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for DOCK3 (50712672 - 50962672 bp, first 250kb of DOCK3)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 21 variations for DOCK3
8 CNVs: 63467 63468 68374 91303 79764 79763 91306 91304
5 Indels: 79765 33371 91305 12302 33370
8 Inversions: 37246 29444 29440 37245 0552 37247 0553 37248
Human Gene Mutation Database (HGMD): DOCK3
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DOCK3 |
|
Disorders
/ Diseases
for DOCK3 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
DOCK3 for disorders About GeneDecksing
OMIM gene information: 603123
OMIM disorders: --
UniProtKB/Swiss-Prot: DOCK3_HUMAN, Q8IZD9
Note=A chromosomal aberration involving DOCK3 has been found in a family with early-onsetbehavioral/developmental disorder with features of attention deficit-hyperactivity disorder and intellectualdisability. Inversion inv(3)(p14:q21). The inversion disrupts DOCK3 and SLC9A9
9  diseases for DOCK3: About MalaCardsattention deficit hyperactivity disorder wiskott-aldrich syndrome saethre-chotzen syndrome autism spectrum disorder
urethra cancer intellectual disability alzheimer's disease crohn's disease
dementia
1 Novoseek disease relationship for DOCK3 gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| alzheimers disease |
25.2 |
1 |
11696419 (1) |
Genetic Association Database (GAD): DOCK3
Human Genome Epidemiology (HuGE) Navigator: DOCK3 (5 documents)
Export disorders for DOCK3 gene to outside databases
|
Publications
for DOCK3 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for DOCK3 gene, integrated from 9 sources (see all 27):
(articles sorted by number of sources associating them with DOCK3) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Disruption of a novel member of a sodium/hydrogen exchanger family and DOCK3 is associated with an attention deficit hyperactivity disorder-like phenotype. (PubMed id 14569117)1, 2, 4 De Silva M.G.... Forrest S. (2003)
- Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9205841)1, 2, 3 Nagase T.... Ohara O. (1997)
- Presenilin binding protein is associated with neurofibrillary alterations in Alzheimer's disease and stimulates tau phosphorylation. (PubMed id 11696419)1, 2, 9 Chen Q.... Masliah E. (2001)
- Identification of an evolutionarily conserved superfamily of DOCK180- related proteins with guanine nucleotide exchange activity. (PubMed id 12432077)1, 2 Cote J.-F. and Vuori K. (2002)
- Isolation and characterization of novel presenilin binding protein. (PubMed id 10854253)1, 2 Kashiwa A.... Kimura H. (2000)
- A novel functional screen in human cells identifies MOCA as a negative regulator of Wnt signaling. (PubMed id 18716063)1, 9 Caspi E. and Rosin-Arbesfeld R. (2008)
- [Role of Dock3 in axonal regeneration]. (PubMed id 22746061)1 Namekata K. and Harada T. (2012)
- MOCA is an integrator of the neuronal death signals th at are activated by familial Alzheimer's disease-related mutants of amyloid b precursor protein and presenilins. (PubMed id 22115042)1 Tachi N....Matsuoka M. (2012)
- Comprehensive analysis of interactions between the Src -associated protein in mitosis of 68 kDa and the human Src-homology 3 proteome. (PubMed id 22745667)1 Asbach B....Wagner R. (2012)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
|
External Searches for DOCK3 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing DOCK3 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing DOCK3 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing DOCK3 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for DOCK3 gene:
Search GeneIP for patents involving DOCK3
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for DOCK3 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for DOCK3 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DOCK3 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DOCK3 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for DOCK3 | | OriGene 3'-UTR Clone for DOCK3 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DOCK3 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DOCK3 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for DOCK3 | | OriGene Custom Protein Services for DOCK3 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat DOCK3 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DOCK3 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DOCK3 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DOCK3 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DOCK3 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DOCK3 |
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 |  |  |  | |
| | | | Search Tocris compounds for DOCK3 |
| |  |  |  |  | | | | |
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 | | | DOCK3 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DOCK3 |
|  |  |  | | | | ThermoFisher Antibodies for DOCK3 |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat DOCK3 |
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