DOC2B Gene
protein-coding GIFtS : 49
GCID: GC17 M000007
double C2-like domains, beta (Previous names: double C2-like domains, beta-like ) (Previous symbol: DOC2BL )
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Aliasesfor DOC2B gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Aliases Double C2-Like Domains, Beta 1 2 DOC2BL1 2 3 Double C2-Like Domains, Beta-Like1 Doc2-Beta1 Double C2-Like Domain-Containing Protein Beta2 Doc2-Beta1
Export aliases for DOC2B gene to outside databases Previous GC identifers: GC17P000349 GC17M000091 GC17P9O0017 GC17P8G0009
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Summariesfor DOC2B gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section Entrez Gene summary for DOC2B : There are at least two protein isoforms of the Double C2 protein, namely alpha (DOC2A) and beta (DOC2B), which contain two C2-like domains. DOC2A and DOC2B are encoded by different genes; these genes are at times confused with the unrelated DAB2 gene which was initially named DOC-2. DOC2B is expressed ubiquitously and is suggested to be involved in Ca(2+)-dependent intracellular vesicle trafficking in various types of cells. (provided by RefSeq, Jul 2008) UniProtKB/Swiss-Prot: DOC2B_HUMAN, Q14184 Function : Calcium sensor which positively regulates SNARE-dependent fusion of vesicles with membranes. Bindsphospholipids in a calcium-dependent manner and may act at the priming stage of fusion by modifying membrane curvature to stimulate fusion. Involved in calcium-triggered exocytosis in chromaffin cells and calcium-dependent spontaneous release of neurotransmitter in absence of action potentials in neuronal cells. Involved both in glucose-stimulated insulin secretion in pancreatic cells and insulin-dependent GLUT4 transport to the plasma membrane in adipocytes (By similarity) Gene Wiki entry for DOC2B
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Genomic Viewsfor DOC2B gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,
and/or miRBase ,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000017.10 NC_018928.1 NT_024972.8 Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the DOC2B gene promoter: Olf-1 AP-4 Tal-1beta E47 POU2F1 Zic1 POU2F1a POU2F1b Chx10 POU2F1c Other transcription factors Search SABiosciences Chromatin IP Primers for DOC2B Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human , mouse , rat DOC2B
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 17p13.3 Ensembl cytogenetic band: 17p13.3 HGNC cytogenetic band: 17p13.3 DOC2B Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc information about chromosome 17 GeneLoc Exon Structure
GeneLoc location for GC17M000007: view genomic region
(about GC identifiers )
Start:
5,810 bp from pter
End:
31,427 bp from pter
Size:
25,618 bases
Orientation:
minus strand
1 alternative location : Chr 17-,PATCHES 6,009-31,420
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Proteinsfor DOC2B gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
Biochemical Assays by
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB/Swiss-Prot: DOC2B_HUMAN, Q14184 (See
protein sequence )Recommended Name: Double C2-like domain-containing protein beta Size : 412 amino acids; 45949 Da
Subunit : Interacts with the SNARE (soluble N-ethylmaleimide-sensitive factor attached protein receptor) complexcomposed of SNAP25, STX1A and VAMP2; the interaction is calcium-dependent and competitive with SYT1. Interacts with STX4; the interaction is calcium-dependent, increased by insulin and glucose, and mediates vesicle fusion with plasma membrane in pancreatic cells and adipocytes. Interacts with STXBP3; the interaction is direct, occurs at the cell membrane and regulates glucose-stimulated insulin secretion. May interact with UNC13A; the interaction mediates targeting to the plasma membrane (By similarity). Interacts with cytoplasmic dynein light chain DYNLT1
Subcellular location : Cytoplasm. Cytoplasmic granule (By similarity). Cell membrane; Peripheral membrane protein (Bysimilarity). Note=Translocates to the plasma membrane in a calcium-dependent manner (By similarity) Explore the universe of human proteins at neXtProt for DOC2B: NX_Q14184 Post-translational modifications:
View modification sites using PhosphoSitePlus 2 View neXtProt modification sites for NX_Q14184 DOC2B Protein expression data from MOPED and PaxDb : About this image
REFSEQ proteins: NP_003576.2 ENSEMBL proteins: ENSP00000343665 Human Recombinant Protein Products: Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view) : About this table
DOC2B for ontologies About GeneDecksing DOC2B Antibody Products: Assay Products for DOC2B:
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Protein
Domains / Familiesfor DOC2B gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section
DOC2B for domains About GeneDecksing 5/6 InterPro domains/families (see all 6 ):
Graphical View of Domain Structure for InterPro Entry Q14184 ProtoNet protein and cluster: Q14184
2 Blocks protein families : IPB000008 C2 domain IPB001565 Synaptotagmin signature UniProtKB/Swiss-Prot: DOC2B_HUMAN, Q14184 Domain : C2 domain 1 is involved in binding calcium and phospholipids. C2 domain 2 may also play a role in thecalcium-dependent targeting to membranes (By similarity) Similarity : Contains 2 C2 domains
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Functionfor DOC2B gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences ,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section Function Summary: UniProtKB/Swiss-Prot: DOC2B_HUMAN, Q14184 Function : Calcium sensor which positively regulates SNARE-dependent fusion of vesicles with membranes. Bindsphospholipids in a calcium-dependent manner and may act at the priming stage of fusion by modifying membrane curvature to stimulate fusion. Involved in calcium-triggered exocytosis in chromaffin cells and calcium-dependent spontaneous release of neurotransmitter in absence of action potentials in neuronal cells. Involved both in glucose-stimulated insulin secretion in pancreatic cells and insulin-dependent GLUT4 transport to the plasma membrane in adipocytes (By similarity)
Clone Products: Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for DOC2B (see all 3 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for DOC2BOriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: DOC2B (NM_003585 ) Browse Sino Biological Human cDNA Clones DNA2.0 Custom Codon Optimized Gene
Synthesis Service for DOC2B Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat DOC2B
In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DOC2B
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view) : About this table
DOC2B for ontologies About GeneDecksing Animal Models: Mouse knock-out Doc2b tm1Aljg for DOC2B 1 MGI mutant phenotype (inferred from 1 allele ) (MGI details for Doc2b) :
DOC2B for phenotypes About GeneDecksing
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Pathways & Interactionsfor DOC2B gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Interactions: Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for DOC2B STRING Interaction
Network Preview (showing 5 interactants - click image to see 23)5/24 Interacting proteins for DOC2B (Q14184 2 ENSP00000343665 4 ) via UniProtKB, MINT, STRING , and/or I2D (see all 24 )About this table Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6 ): About this table
GO ID Qualified GO term Evidence PubMed IDs GO:0006887 exocytosis
-- -- GO:0008104 protein localization
ISS -- GO:0031340 positive regulation of vesicle fusion
ISS -- GO:0032024 positive regulation of insulin secretion
ISS -- GO:0045956 positive regulation of calcium ion-dependent exocytosis
ISS --
DOC2B for ontologies About GeneDecksing
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Drugs & Compoundsfor DOC2B gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section Browse Tocris compounds for DOC2B 1 HMDB Compound for DOC2B About this table Search CenterWatch for drugs/clinical trials and news about DOC2B
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Transcriptsfor DOC2B gene (Secondary structures according to
fRNAdb ,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
microRNA from QIAGEN ,
Tagged/untagged cDNA clones from
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section REFSEQ mRNAs for DOC2B gene: NM_003585.3 Unigene Cluster for DOC2B:
Double C2-like domains, beta Hs.551705 [show with all ESTs ] Unigene Representative Sequence: D70830 2 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000343572 (uc010vpx.1 ) ENST00000575802 Clone Products: OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for DOC2B (see all 3 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for DOC2BOriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: DOC2B (NM_003585 ) DNA2.0 Custom Codon Optimized Gene
Synthesis Service for DOC2B Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat DOC2B
Additional cDNA sequence: D70830.1
2 DOTS entries : DT.40113573 DT.99979978
6 AceView cDNA sequences :
BM713588 BU739610 D70830 NM_003585 BF434293 BF509185 GeneLoc Exon Structure
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Expression for DOC2B gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,
PCR Arrays from
SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section DOC2B expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: CTTCACTCAA
About this image DOC2B expression in embryonic tissues and stem cells Expression by the Database of Embryonic development, Stem cell research, and
Regenerative medicine About this table See DOC2B Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for DOC2B SOURCE GeneReport for Unigene cluster: Hs.551705 UniProtKB/Swiss-Prot: DOC2B_HUMAN, Q14184 Tissue specificity : Widely expressed with highest levels in brain and kidney. Expressed in pancreatic islet cells (atprotein level) SABiosciences Custom PCR Arrays for DOC2B Primer Products: OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for DOC2BBrowse OriGene validated miRNA SYBR primer pairs SABiosciences RT2 qPCR Primer Assay in human , mouse , rat DOC2B QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat DOC2B QIAGEN QuantiFast Probe-based Assays in human , mouse , rat DOC2B In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DOC2B
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Orthologsfor DOC2B gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section
This gene was present in the common ancestor of animals.
Orthologs for DOC2B gene from 5/18 species (see all 18 ) About this table
Organism
Taxonomic classification
Gene
Description
Human Similarity
Orthology Type
Details
chicken (Gallus gallus)
Aves
DOC2B1
double C2-like domains, beta
82.75(n) 88.69(a)
 
417624 XM_415868.2 XP_415868.2
lizard (Anolis carolinensis)
Reptilia
DOC2B6
--
1 ↔ 1
AAWZ02038570(4748-9523)
zebrafish (Danio rerio)
Actinopterygii
doc2b1
double C2-like domains, beta
74.03(n) 79.95(a)
 
100006713 XM_001345351.4 XP_001345387.4
fruit fly (Drosophila melanogaster)
Insecta
rabphilin-3A3
synaptic vesicle endocytosis protein transporter
39(a)
 
--
worm (Caenorhabditis elegans)
Secernentea
rbf-16 snt-66
SyNapTotagmin family member (snt-6)
9(a) 15(a)
1 ↔ manypossible ortholog
III(6675748-6703943) II(745469-750171)
ENSEMBL Gene Tree for DOC2B (if available)TreeFam Gene Tree for DOC2B (if available)
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Paralogsfor DOC2B gene (Paralogs according to
1 HomoloGene , 2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section Paralogs for DOC2B gene SYTL4 2 SYTL5 2 SYTL1 2 DOC2A 2 SYTL3 2 RPH3A 2 SYTL2 2 9 SIMAP similar genes for DOC2B using alignment to 1 protein entry: DOC2B_HUMAN :RPH3A DOC2A SYT1 SYT14L SYT5 SYT2 SYT4 SYT7 SYT11
DOC2B for paralogs About GeneDecksing 2 Pseudogenes.org Pseudogenes for DOC2B PGOHUM00000237123 PGOHUM00000237452
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Genomic Variantsfor DOC2B gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section
Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical significance Chr 17 pos Sequence # AA Chg Type More # Allele freq Pop Total sample More
HapMap Linkage Disequilibrium report for DOC2B (5810 - 31427 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 8 variations for DOC2B 6 CNVs : 72723 67090 72721 102367 72722 72720 2 Indels : 25886 25788
SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing DOC2B
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Disorders
/ Diseasesfor DOC2B gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section
DOC2B for disorders About GeneDecksing
OMIM gene information: 604568
OMIM disorders : --6 diseases for DOC2B : About MalaCards miller-dieker syndrome amyotrophic lateral sclerosis lateral sclerosis lissencephaly pancreatitis neuronitis Human Genome Epidemiology (HuGE) Navigator: DOC2B (1 document)Export disorders for DOC2B gene to outside databases
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Publicationsfor DOC2B gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for DOC2B gene, integrated from 9 sources (see all 15 ): (articles sorted by number of sources associating them with DOC2B) Utopia : connect your pdf to the dynamic world of online information
Molecular cloning of an isoform of Doc2 having two C2-like domains. (PubMed id 8554557) 1 , 2 , 9 Sakaguchi G.... Takai Y. (1995) Interaction of Doc2 with tctex-1, a light chain of cytoplasmic dynein. Implication in dynein-dependent vesicle transport. (PubMed id 9804756) 1 , 2 Nagano F.... Takai Y. (1998) Doc2, a novel synaptic vesicle protein with two repeated C2-like domains. (PubMed id 7826360) 1 , 3 Orita S.... Takai Y. (1995) Resequencing of 29 candidate genes in patients with familial and sporadic amyotrophic lateral sclerosis. (PubMed id 21220648) 2 Daoud H....Rouleau G.A. (2011) Doc2 is a Ca2+ sensor required for asynchronous neuro transmitter release. (PubMed id 22036572) 1 Yao J....Chapman E.R. (2011) Genome-wide association study implicates PARD3B-based AIDS restriction. (PubMed id 21502085) 1 Troyer J.L....O'Brien S.J. (2011) Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614) 1 Rose J.E....Uhl G.R. (2010) Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348) 1 Barbe L....Andersson-Svahn H. (2008) Doc2beta is a novel Munc18c-interacting partner and positive effector of syntaxin 4-mediated exocytosis. (PubMed id 17548353) 2 Ke B....Thurmond D.C. (2007) Refinement of a 400-kb critical region allows genotypic differentiation between isolated lissencephaly, Miller-Dieker syndrome, and other phenotypes secondary to deletions of 17p13.3. (PubMed id 12621583) 1 Cardoso C....Ledbetter D.H. (2003)
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External Searches for DOC2B gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing DOC2B gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
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Other Databases showing DOC2B gene
(According to HUGE )
About This Section --
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Specialized Databases showing DOC2B gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
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PharmGKB entry for DOC2B Pharmacogenomics, SNPs, Pathways
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About This Section Patent Information for DOC2B gene: Search GeneIP for patents involving DOC2B GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor DOC2B gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript and LifeMap BioReagents , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences ), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
Browse OriGene Antibodies OriGene shRNA RFP for DOC2B OriGene 29mer shRNA kits in GFP-retroviral vector in human , mouse , rat for DOC2B OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for DOC2B OriGene Protein Over-expression Lysate for DOC2B Browse OriGene Fluorogenic Cell Assay Kits OriGene siRNA for DOC2B Browse 3'-UTR reporter clones for miRNA target validation OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for DOC2B OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for DOC2B Browse OriGene GFP tagged cDNA clones in CMV expression vector Browse OriGene MicroRNA Expression Plasmids Browse OriGene basic RS shRNAs Browse OriGene validated miRNA SYBR primer pairs Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling OriGene Custom Antibody Services for DOC2B OriGene Custom Protein Services for DOC2B OriGene Custom Immunoassay Development
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat DOC2B QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing DOC2B QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human , mouse , rat DOC2B QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human , mouse , rat DOC2B QIAGEN QuantiFast Probe-based Assays in human , mouse , rat DOC2B QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat DOC2B
Search Tocris compounds for DOC2B
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DOC2B
Search ThermoFisher Antibodies for DOC2B
Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat DOC2B
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Aliases for DOC2B
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Drugs / Compounds for DOC2B
Expression for DOC2B
Function for DOC2B
Genomic Views for DOC2B
Intellectual Property for DOC2B
Orthologs for DOC2B
Paralogs for DOC2B
Pathways / Interactions for DOC2B
Products for DOC2B
Proteins for DOC2B
Publications for DOC2B
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Summaries for DOC2B
Transcripts for DOC2B
Variants for DOC2B
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