Aliases for DNTTIP1 Gene
External Ids for DNTTIP1 Gene
Previous Symbols for DNTTIP1 Gene
DNTTIP1 binds DNA and enhances the activity of terminal deoxynucleotidyltransferase (TDT, or DNTT; MIM 187410), a DNA polymerase that catalyzes the polymerization of DNA in the absence of a DNA template (Yamashita et al., 2001 [PubMed 11473582]).[supplied by OMIM, Mar 2008]
GeneCards Summary for DNTTIP1 Gene
DNTTIP1 (Deoxynucleotidyltransferase, Terminal, Interacting Protein 1) is a Protein Coding gene.
UniProtKB/Swiss-Prot for DNTTIP1 Gene
Increases DNTT terminal deoxynucleotidyltransferase activity (in vitro) (PubMed:11473582). Also acts as a transcriptional regulator, binding to the consensus sequence 5-GNTGCATG-3 following an AT-tract. Associates with RAB20 promoter and positively regulates its transcription. Binds DNA and nucleosomes; may recruit HDAC1 complexes to nucleosomes or naked DNA.