Aliases for DNTTIP1 Gene
External Ids for DNTTIP1 Gene
Previous HGNC Symbols for DNTTIP1 Gene
Previous GeneCards Identifiers for DNTTIP1 Gene
DNTTIP1 binds DNA and enhances the activity of terminal deoxynucleotidyltransferase (TDT, or DNTT; MIM 187410), a DNA polymerase that catalyzes the polymerization of DNA in the absence of a DNA template (Yamashita et al., 2001 [PubMed 11473582]).[supplied by OMIM, Mar 2008]
GeneCards Summary for DNTTIP1 Gene
DNTTIP1 (Deoxynucleotidyltransferase, Terminal, Interacting Protein 1) is a Protein Coding gene.
UniProtKB/Swiss-Prot for DNTTIP1 Gene
Increases DNTT terminal deoxynucleotidyltransferase activity (in vitro) (PubMed:11473582). Also acts as a transcriptional regulator, binding to the consensus sequence 5-GNTGCATG-3 following an AT-tract. Associates with RAB20 promoter and positively regulates its transcription. Binds DNA and nucleosomes; may recruit HDAC1 complexes to nucleosomes or naked DNA.