Aliases for DNTT Gene
Aliases for DNTT Gene
External Ids for DNTT Gene
- HGNC: 2983
- Entrez Gene: 1791
- Ensembl: ENSG00000107447
- OMIM: 187410
- UniProtKB: P04053
Previous GeneCards Identifiers for DNTT Gene
- GC10P096957
- GC10P097297
- GC10P098195
- GC10P097728
- GC10P098054
- GC10P091692
- GC10P098072
Summaries for DNTT Gene
-
This gene is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [provided by RefSeq, Jul 2008]
GeneCards Summary for DNTT Gene
DNTT (DNA Nucleotidylexotransferase) is a Protein Coding gene. Diseases associated with DNTT include Lymphoblastic Lymphoma and Acute Leukemia. Among its related pathways are DNA Double-Strand Break Repair and Hematopoietic cell lineage. GO annotations related to this gene include DNA-directed DNA polymerase activity and DNA polymerase activity. An important paralog of this gene is POLB.
UniProtKB/Swiss-Prot for DNTT Gene
-
Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5-triphosphate to the 3-end of a DNA initiator. One of the in vivo functions of this enzyme is the addition of nucleotides at the junction (N region) of rearranged Ig heavy chain and T-cell receptor gene segments during the maturation of B- and T-cells.
No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for DNTT Gene
Genomics for DNTT Gene
Regulatory Elements for DNTT Gene
Enhancers for DNTT Gene
| GeneHancer Identifier | Score | Enhancer Sources | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Other Gene Targets for Enhancer |
|---|
Enhancers around DNTT on UCSC Golden Path with GeneCards custom track
Promoters for DNTT Gene
| Ensembl Regulatory Elements (ENSRs) | TSS Distance (bp) | Size (bp) | Binding Sites for Transcription Factors within promoters |
|---|
ENSRs around DNTT on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for DNTT Gene
- Chromosome:
- 10
- Start:
- 96,304,328 bp from pter
- End:
- 96,338,564 bp from pter
- Size:
- 34,237 bases
- Orientation:
- Plus strand
Genomic View for DNTT Gene
Genes around DNTT on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 10q24.1 by Ensembl
- 10q23-q24 by Entrez Gene
- 10q23-q24 by HGNC
DNTT Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for DNTT Gene
Proteins for DNTT Gene
-
Protein details for DNTT Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P04053-TDT_HUMAN
- Recommended name:
- DNA nucleotidylexotransferase
- Protein Accession:
- P04053
- Q53FH1
- Q5W103
- Q96E50
Protein attributes for DNTT Gene
- Size:
- 509 amino acids
- Molecular mass:
- 58536 Da
- Cofactor:
- Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
- Quaternary structure:
-
- Interacts with PRP19 and DNTTIP1. Forms a ternary complex with DNTTIP2 and core histone. Released from this complex by PCNA. Interacts with TRERF1 (PubMed:16371131).
Protein Expression for DNTT Gene
Selected DME Specific Peptides for DNTT Gene
Post-translational modifications for DNTT Gene
Other Protein References for DNTT Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for DNTT
- Abcam antibodies for TdT
- Invitrogen Antibodies for DNTT
- antibodies-online Antibodies for DNTT: See all 148
- GeneTex DNTT antibody for DNTT
-
Santa Cruz Biotechnology (SCBT) Antibodies for DNTT
Protein Products
-
OriGene Purified Proteins for DNTT
- Search Origene for MassSpec and Protein Over-expression Lysates for DNTT
- Origene Custom Protein Services for DNTT
- antibodies-online Proteins for DNTT: See all 5
- Search antibodies-online for peptides
- Search GeneTex for Proteins for DNTT
- Abcam proteins for TdT
Assay Products
- antibodies-online Kits for DNTT: See all 11
Domains & Families for DNTT Gene
Gene Families for DNTT Gene
Protein Domains for DNTT Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for DNTT Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
P04053UniProtKB/Swiss-Prot:
TDT_HUMAN :- Contains 1 BRCT domain.
- Belongs to the DNA polymerase type-X family.
- Domain:
-
- Contains 1 BRCT domain.
- Family:
-
- Belongs to the DNA polymerase type-X family.
Function for DNTT Gene
Molecular function for DNTT Gene
- GENATLAS Biochemistry:
- deoxynucleotidyltransferase,terminal
- UniProtKB/Swiss-Prot CatalyticActivity:
- Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
- UniProtKB/Swiss-Prot Function:
- Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5-triphosphate to the 3-end of a DNA initiator. One of the in vivo functions of this enzyme is the addition of nucleotides at the junction (N region) of rearranged Ig heavy chain and T-cell receptor gene segments during the maturation of B- and T-cells.
Enzyme Numbers (IUBMB) for DNTT Gene
- EC 2.7.7.31 63 4
- EC 2.7.7 63
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003887 | DNA-directed DNA polymerase activity | IEA | -- |
| GO:0046872 | metal ion binding | IEA | -- |
Phenotypes for DNTT Gene
- MGI mutant phenotypes for DNTT:
- inferred from 4 alleles
- GenomeRNAi human phenotypes for DNTT:
-
- Increased vaccinia virus (VACV) infection
- shRNA abundance <= 50%
- Dynamic nuclei (hole, folded or small irregular)
- Decreased NF-kappaB reporter expression
- Increased transferrin (TF) endocytosis
- Decreased shRNA abundance (Z-score < -2)
- Increased shRNA abundance (Z-score > 2)
- Increased viability with MLN4924 (a NAE inhibitor)
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
-
ViGene Biosciences lentiviral particle packaged cDNA for DNTT gene
-
ViGene Biosciences ready-to-package AAV shRNAs for DNTT gene
- Search ViGene Biosciences for DNTT
CRISPR Products
-
OriGene CRISPR knockouts for DNTT
-
Santa Cruz Biotechnology (SCBT) CRISPR for DNTT
- GenScript: Design CRISPR guide RNA sequences for DNTT
miRNA Products
- Search ViGene Biosciences for DNTT
Clone Products
- OriGene clones in human for DNTT
- OriGene ORF clones in human,mouse,rat for DNTT
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Cell Line Products
-
ViGene Biosciences adenoviral particle packaged cDNA for DNTT gene
-
ViGene Biosciences lentiviral particle packaged cDNA for DNTT gene
-
ViGene Biosciences ready-to-package AAV shRNAs for DNTT gene
Flow Cytometry Products
- eBioscience FlowRNA Probe Sets (VA1-12428) for DNTT
No data available for Human Phenotype Ontology , miRNA , Transcription Factor Targets and HOMER Transcription for DNTT Gene
Localization for DNTT Gene
Subcellular locations from UniProtKB/Swiss-Prot for DNTT Gene
- Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 4 |
| mitochondrion | 3 |
| cytoskeleton | 2 |
| endoplasmic reticulum | 2 |
| extracellular | 2 |
| plasma membrane | 2 |
| vacuole | 2 |
| lysosome | 1 |
No data available for Gene Ontology (GO) - Cellular Components for DNTT Gene
Pathways & Interactions for DNTT Gene
More details on SuperPathways for DNTTPathways by source for DNTT Gene
1 BioSystems pathway for DNTT Gene
2 KEGG pathways for DNTT Gene
Interacting Proteins for DNTT Gene
Selected Interacting proteins:
ENSP00000360216
P04053-TDT_HUMAN
for DNTT Gene via
STRING
UniProtKB
I2D
No data available for SIGNOR curated interactions for DNTT Gene
Drugs & Compounds for DNTT Gene
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
|---|---|---|---|---|---|---|
| phosphoric acid |
|
7664-38-2 |
|
Drug Products
- Enzo Life Sciences drugs & compounds for DNTT
Transcripts for DNTT Gene
mRNA/cDNA for DNTT Gene
- (3) REFSEQ mRNAs :
- (7) Additional mRNA sequences :
- (21) Selected AceView cDNA sequences:
- (2) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for DNTT Gene
CRISPR Products
-
OriGene CRISPR knockouts for DNTT
-
Santa Cruz Biotechnology (SCBT) CRISPR for DNTT
- GenScript: Design CRISPR guide RNA sequences for DNTT
miRNA Products
- Search ViGene Biosciences for DNTT
Clone Products
- OriGene clones in human for DNTT
- OriGene ORF clones in human,mouse,rat for DNTT
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Flow Cytometry Products
- eBioscience FlowRNA Probe Sets (VA1-12428) for DNTT
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | |||||||||||||||||||||||||
| SP2: | |||||||||||||||||||||||||
| SP3: | - |
Expression for DNTT Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Blood (Hematopoietic System)
- Pro B-Cells Hematopoietic Bone Marrow
mRNA differential expression in normal tissues according to GTEx for DNTT Gene
This gene is overexpressed in Testis (x16.5) and Whole Blood (x6.1).
This gene is overexpressed in Liver, secretome (42.5) and Lung (24.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for DNTT Gene
SOURCE GeneReport for Unigene cluster for DNTT Gene Hs.534206
Primer Products
-
OriGene qPCR primer pairs for DNTT
-
OriGene qPCR primer pairs and template standards for DNTT
No data available for mRNA Expression by UniProt/SwissProt for DNTT Gene
Orthologs for DNTT Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| cow (Bos Taurus) |
Mammalia | DNTT 35 |
|
||
| DNTT 36 |
|
OneToOne | |||
| dog (Canis familiaris) |
Mammalia | DNTT 35 |
|
||
| DNTT 36 |
|
OneToOne | |||
| mouse (Mus musculus) |
Mammalia | Dntt 35 |
|
||
| Dntt 16 |
|
||||
| Dntt 36 |
|
OneToOne | |||
| chimpanzee (Pan troglodytes) |
Mammalia | DNTT 35 |
|
||
| DNTT 36 |
|
OneToOne | |||
| rat (Rattus norvegicus) |
Mammalia | Dntt 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | DNTT 36 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | DNTT 36 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | DNTT 35 |
|
||
| DNTT 36 |
|
OneToOne | |||
| lizard (Anolis carolinensis) |
Reptilia | DNTT 36 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | dntt 35 |
|
||
| African clawed frog (Xenopus laevis) |
Amphibia | dntt-A 35 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | dntt 35 |
|
||
| dntt 36 |
|
OneToOne | |||
| rainbow trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.11749 35 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 36 |
|
OneToMany |
- Species with no ortholog for DNTT:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for DNTT Gene
(1) SIMAP similar genes for DNTT Gene using alignment to 2 proteins:
Variants for DNTT Gene
| SNP ID | Clin | Chr 10 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs6584066 | - | 96,318,482(+) | GCATA(A/G)GAGCA | reference, missense | |
| rs1815258 | -- | 96,311,705(-) | GATCG(C/T)GCCAC | intron-variant | |
| rs1885680 | -- | 96,317,876(-) | CATGG(A/T)TTAAG | intron-variant | |
| rs1923690 | -- | 96,316,827(-) | TTACA(C/T)GAAAC | intron-variant | |
| rs1923691 | -- | 96,303,267(-) | AGATG(C/G)AGTTT | upstream-variant-2KB |
Residual Variation Intolerance Score:
80.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
2.52;
44.08% of all genes are more intolerant (likely to be disease-causing)
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for DNTT Gene
Disorders for DNTT Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| lymphoblastic lymphoma |
|
|
| acute leukemia |
|
|
| leukemia, acute lymphoblastic |
|
|
| burkitt lymphoma |
|
|
| ewing sarcoma |
|
Search DNTT in MalaCards
View complete list of genes associated with diseases
Relevant External Links for DNTT
No data available for UniProtKB/Swiss-Prot and Genatlas for DNTT Gene
Publications for DNTT Gene
- Mutational analysis of residues in the nucleotide binding domain of human terminal deoxynucleotidyl transferase. (PMID: 8163485) Yang B. … Coleman M.S. (J. Biol. Chem. 1994) 3 4 23 67
- Bood POZ containing gene type 2 is a human counterpart of yeast Btb3p and promotes the degradation of terminal deoxynucleotidyltransferase. (PMID: 18429817) Maezawa S. … Koiwai O. (Genes Cells 2008) 3 23
- Identification of functional domains in TdIF1 and its inhibitory mechanism for TdT activity. (PMID: 17663723) Kubota T. … Koiwai O. (Genes Cells 2007) 3 23
- Nonpositive terminal deoxynucleotidyl transferase in pediatric precursor B-lymphoblastic leukemia. (PMID: 15198352) Liu L. … Liang X. (Am. J. Clin. Pathol. 2004) 3 23
- Association of terminal deoxynucleotidyl transferase with Ku. (PMID: 10570175) Mahajan K.N. … Mitchell B.S. (Proc. Natl. Acad. Sci. U.S.A. 1999) 3 23
Products for DNTT Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
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- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
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- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for DNTT
- Search Origene for MassSpec and Protein Over-expression Lysates for DNTT
- Origene Custom Protein Services for DNTT
- Origene siRNA, shRNA, mouse_rna, rat_shrna, and RNAi products in human, mouse, rat for DNTT
- Browse OriGene Inhibitory RNA Products For DNTT
- OriGene qPCR primer pairs for DNTT
- OriGene qPCR primer pairs and template standards for DNTT
- OriGene CRISPR knockouts for DNTT
- OriGene clones in human for DNTT
- OriGene ORF clones in human,mouse,rat for DNTT
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- GenScript: Next-day shipping cDNA clones in your preferred vector
- GenScript Custom Purified and Recombinant Proteins Services for DNTT
- GenScript Custom Assay Services for DNTT
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- GenScript: Design CRISPR guide RNA sequences for DNTT
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
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- Plasmid Preparation
- GenScript Custom Peptide Services for DNTT
- Novus Biologicals Antibodies for DNTT
- Novus Biologicals proteins and lysates for DNTT
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Abcam antibodies for TdT
- Abcam proteins for TdT
- Search for Assays for DNTT at Abcam
- Find your target
- Search knockout validated antibodies
- Browse monoclonal antibodies
- antibodies-online Antibodies for DNTT: See all 148
- antibodies-online Kits for DNTT: See all 11
- antibodies-online Proteins for DNTT: See all 5
- Search antibodies-online for peptides
- GeneTex DNTT antibody for DNTT
- Search GeneTex for Proteins for DNTT
- ViGene Biosciences adenoviral particle packaged cDNA for DNTT gene
- ViGene Biosciences lentiviral particle packaged cDNA for DNTT gene
- ViGene Biosciences lentiviral particle packaged cDNA for DNTT gene
- ViGene Biosciences ready-to-package AAV shRNAs for DNTT gene
- ViGene Biosciences ready-to-package AAV shRNAs for DNTT gene
- ViGene Biosciences ready-to-package AAV shRNAs for DNTT gene
- Search ViGene Biosciences for DNTT
- Search ViGene Biosciences for DNTT
- Santa Cruz Biotechnology (SCBT) Antibodies for DNTT
- Search Santa Cruz Biotechnology (SCBT) for DNTT siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for DNTT
Sources for DNTT Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) I2D
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) UniGene
- (28) AceView
- (29) RNAdb
- (30) ASD
- (31) ECgene
- (32) GeneAnnot
- (33) SAGE
- (34) SOURCE
- (35) HomoloGene
- (36) PanEnsembl
- (37) euGenes
- (38) SGD
- (39) FlyBase
- (40) WormBase
- (41) Pseudogene
- (42) DGV
- (43) dbSNP
- (44) HapMap
- (45) GenAtlas
- (46) GeneTests
- (47) HGMD
- (48) GAD
- (49) LSDB
- (50) BGMUT
- (51) HuGE
- (52) eBioscience
- (53) Atlas
- (54) Cell Signaling Technology
- (55) GenBank
- (56) H-invDB
- (57) HORDE
- (58) HUGE
- (59) IMGT
- (60) Leiden
- (61) MILLIPORE
- (62) miRBase
- (63) DME
- (64) Nature
- (65) NCBI
- (66) OriGene
- (67) PubMed
- (68) R&D Systems
- (69) Salk
- (70) TGDB
- (71) Tufts
- (72) YEDA
- (73) CROW21
- (74) Tocris
- (75) Abcam
- (76) Novus
- (77) ProSpec
- (78) Sino Biological
- (79) GenScript
- (80) Qiagen
- (81) Cloud-Clone Corp.
- (82) Enzo Life Sciences
- (83) OCA
- (84) Proteopedia
- (85) MOPED
- (86) SPIRE
- (87) neXtProt
- (88) Reactome
- (89) GeneGo (Thomson Reuters)
- (90) fRNAdb
- (91) DISEASES
- (92) SIMAP
- (93) GenomeRNAi
- (94) LifeMap
- (95) miRTarBase
- (96) MalaCards
- (97) Invitrogen
- (98) BitterDB
- (99) Vector BioLabs
- (100) ESI-BIO
- (101) RefSeq
- (102) BioSystems
- (103) MaxQB
- (104) IUPHAR
- (105) BioGPS
- (106) Illumina
- (107) COMPARTMENTS
- (108) HOMER
- (109) PaxDb
- (110) ApexBio
- (111) Addgene
- (112) Advanced Cell Diagnostics
- (113) antibodies-online
- (114) CYP
- (115) NONCODE
- (116) SwitchGear Genomics
- (117) TreeFam
- (118) PathCards
- (119) GeneReviews
- (120) GeneTex
- (121) Taconic Biosciences
- (122) GTEx
- (123) ProteomicsDB
- (124) SCBT
- (125) DGIdb
- (126) ClinicalTrials
- (127) FDA Approved Drugs
- (128) RVIS
- (129) SIGNOR
- (130) diseasecard
- (131) NIH Rare Diseases
- (132) Orphanet
- (133) UMLS
- (134) GTR
- (135) Disease Ontology
- (136) Genetics Home Reference
- (137) MeSH
- (138) MedlinePlus
- (139) CDC
- (140) NINDS
- (141) NCBI Bookshelf
- (142) ClinVar
- (143) Gene Damage Index
- (144) ViGene Biosciences
- (145) HPO
- (146) UDN
- (147) VISTA
- (148) FANTOM5
- (149) ENCODE
- (150) ProSci
- (151) Horizon