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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

DNPEP Gene

protein-coding   GIFtS: 57
GCID: GC02M220238

aspartyl aminopeptidase

 Explore 9 diseases affiliated with
DNPEP via our new
 Human Malady Compendium 
Biological research products
for DNPEP
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Aspartyl Aminopeptidase1 2
ASPEP1 2 3
DAP1 2 3
EC 3.4.11.213 8

External Ids:    HGNC: 29811   Entrez Gene: 235492   Ensembl: ENSG000001239927   OMIM: 6113675   UniProtKB: Q9ULA03   

Export aliases for DNPEP gene to outside databases

Previous GC identifers: GC02M218261 GC02M218959 GC02M220201 GC02M220440 GC02M220063 GC02M219946 GC02M212091


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for DNPEP:
The protein encoded by this gene is an aminopeptidase which prefers acidic amino acids, and specifically favors
aspartic acid over glutamic acid. It is thought to be a cytosolic protein involved in general metabolism of
intracellular proteins. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: DNPEP_HUMAN, Q9ULA0
Function: Aminopeptidase with specificity towards an acidic amino acid at the N-terminus. Likely to play an important
role in intracellular protein and peptide metabolism

Gene Wiki entry for DNPEP


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000002.11  NC_018913.1  NT_005403.17  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the DNPEP gene promoter:
         TBP   ATF-2   FOXO1a   MyoD   c-Jun   FOXO1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidDNPEP promoter sequence
   Search SABiosciences Chromatin IP Primers for DNPEP

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DNPEP


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q35   Ensembl cytogenetic band:  2q35   HGNC cytogenetic band: 2q36.1

DNPEP Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DNPEP gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02M220238:  view genomic region     (about GC identifiers)

Start:
220,238,180 bp from pter      End:
220,264,744 bp from pter
Size:
26,565 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: DNPEP_HUMAN, Q9ULA0 (See protein sequence)
Recommended Name: Aspartyl aminopeptidase  
Size: 475 amino acids; 52428 Da
Cofactor: Binds 2 zinc ions per subunit
Subunit: Tetrahedron-shaped homododecamer built from six homodimers
Subcellular location: Cytoplasm
Caution: It is uncertain whether Met-1 or Met-5 is the initiator
Sequence caution: Sequence=BAA92014.1; Type=Erroneous initiation;
1 PDB 3D structure from and Proteopedia for DNPEP:
4DYO (3D)    
Secondary accessions: Q9BW44 Q9NUV5

Explore the universe of human proteins at neXtProt for DNPEP: NX_Q9ULA0

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9ULA0

  • 4/10 DME Specific Peptides for DNPEP (Q9ULA0) (see all 10)
     GAHTDSP  AMHSIRE  SADMAHA  NENFGPN 

    DNPEP Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_036232.2  
    ENSEMBL proteins: 
     ENSP00000273075   ENSP00000363083   ENSP00000431076   ENSP00000363074   ENSP00000363077  
     ENSP00000410684   ENSP00000400944   ENSP00000429960   ENSP00000317252   ENSP00000412003  
     ENSP00000414739   ENSP00000429468   ENSP00000428531   ENSP00000430630  

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    Browse ProSpec Recombinant Proteins
    Uscn Proteins for DNPEP

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IEA--


    DNPEP for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    DNPEP for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR023358 Peptidase_M18_dom2
     IPR001948 Peptidase_M18

    Graphical View of Domain Structure for InterPro Entry Q9ULA0

    ProtoNet protein and cluster: Q9ULA0

    1 Blocks protein family: IPB001948 Aminopeptidase I zinc metalloprotease (M18) signature

    UniProtKB/Swiss-Prot: DNPEP_HUMAN, Q9ULA0
    Similarity: Belongs to the peptidase M18 family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: DNPEP_HUMAN, Q9ULA0
    Function: Aminopeptidase with specificity towards an acidic amino acid at the N-terminus. Likely to play an important
    role in intracellular protein and peptide metabolism
    Catalytic activity: Release of an N-terminal aspartate or glutamate from a peptide, with a preference for aspartate
    Enzyme regulation: One of the zinc ions is readily exchangeable with other divalent cations such as manganese, which
    strongly stimulates the enzymatic activity (By similarity)

    Enzyme Number (IUBMB): EC 3.4.11.211 2

    miRNA
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    hsa-mir-183 (MIRT005726)

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    hsa-miR-4251 hsa-miR-146a hsa-miR-218-1* hsa-miR-519e* hsa-miR-4267 hsa-miR-515-5p hsa-miR-1207-3p hsa-miR-1264
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DNPEP

    Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004177aminopeptidase activity IEA--
    GO:0008237metallopeptidase activity IEA--
    GO:0008270zinc ion binding IEA--


    DNPEP for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for DNPEP:
     Synthetic lethal with Ras 


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for DNPEP

    STRING Interaction Network Preview (showing 5 interactants - click image to see 23)

    5/34 Interacting proteins for DNPEP (Q9ULA03 ENSP000002730754) via UniProtKB, MINT, STRING, and/or I2D (see all 34)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SAT1P216733, ENSP000003685724I2D: score=4 STRING: ENSP00000368572
    KRT31Q153233, ENSP000002516454I2D: score=2 STRING: ENSP00000251645
    KRT82Q9NSB43, ENSP000002579744I2D: score=2 STRING: ENSP00000257974
    NTMT1Q9BV863, ENSP000003615584I2D: score=2 STRING: ENSP00000361558
    AGTP010193, ENSP000003556274I2D: score=1 STRING: ENSP00000355627
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006508proteolysis IEA--
    GO:0006518peptide metabolic process TAS9632644


    DNPEP for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for DNPEP

    1 HMDB Compound for DNPEP    About this table
    CompoundSynonyms CAS #PubMed Ids
    L-Glutamic acid(2S)-2-Aminopentanedioate (see all 49)56-86-0--

    1 DrugBank Compound for DNPEP    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    L-Glutamic Acid(2S)-2-Aminopentanedioic acid (see all 15)56-86-0target--17139284 17928682 17016423

    Search CenterWatch for drugs/clinical trials and news about DNPEP 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for DNPEP gene: 
    NM_012100.2  

    Unigene Cluster for DNPEP:

    Aspartyl aminopeptidase
    Hs.258551  [show with all ESTs]
    Unigene Representative Sequence: NM_012100
    18/21 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 21):
    ENST00000273075(uc002vle.2 uc002vli.2 uc010zlg.2) ENST00000373972
    ENST00000523282 ENST00000373963 ENST00000373966 ENST00000490371 ENST00000488051
    ENST00000462779 ENST00000488881 ENST00000457935 ENST00000429013 ENST00000521459
    ENST00000460963(uc002vlj.2) ENST00000522421 ENST00000322176 ENST00000434339
    ENST00000430206 ENST00000520694

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    hsa-miR-4251 hsa-miR-146a hsa-miR-218-1* hsa-miR-519e* hsa-miR-4267 hsa-miR-515-5p hsa-miR-1207-3p hsa-miR-1264
    Browse SwitchGear 3'UTR luciferase reporter plasmids
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    OriGene shRNA RFP: DNPEP
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    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DNPEP
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DNPEP
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DNPEP

    Additional cDNA sequence: 

    AF005050.2 AK001777.1 AK001977.1 AK021871.1 AK023005.1 AK301919.1 AK302809.1 BC000653.2 
    BC003040.1 BC004854.2 

    23 DOTS entries:

    DT.91773214  DT.100880698  DT.100030734  DT.100880705  DT.100880710  DT.100880715  DT.100030732  DT.121010116 
    DT.95160011  DT.100880711  DT.91773222  DT.100880702  DT.100880712  DT.100808515  DT.100843473  DT.100880681 
    DT.121010107  DT.121640141  DT.121640144  DT.91773216  DT.40271444  DT.86858245  DT.91878637 

    24/445 AceView cDNA sequences (see all 445):

    BX387640 BC000653 BI753578 AA565854 AF005050 CR623295 BU733421 AA470831 
    BM709458 CR603497 BQ029776 CR601156 BI755275 AW044568 BX401446 BU162343 
    BI821651 CR616703 CR607064 BU521296 CR605526 BM978058 BM974153 BI823360 

    GeneLoc Exon Structure

    5/11 Alternative Splicing Database (ASD) splice patterns (SP) for DNPEP (see all 11)    About this scheme

    ExUns: 1 ^ 2 ^ 3a · 3b · 3c · 3d ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8a · 8b · 8c ^ 9a · 9b ^ 10a · 10b ^ 11a · 11b ^ 12 ^ 13a · 13b ^ 14a · 14b ^ 15a ·
    SP1:              -     -     -     -           -                                   -     -                 -     -                       -     -           -   
    SP2:                                -                                               -     -                 -     -                       -     -           -   
    SP3:                                -           -                                   -     -                                                                     
    SP4:                                                                                -     -                                                                     
    SP5:                                                                                -     -     -     -     -     -                       -     -           -   

    ExUns: 15b ^ 16a · 16b · 16c ^ 17a · 17b
    SP1:                                    
    SP2:                                    
    SP3:                                    
    SP4:                                    
    SP5:                                    


    ECgene alternative splicing isoforms for DNPEP

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    DNPEP expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CACTCTATCC

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See DNPEP Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for DNPEP

    SOURCE GeneReport for Unigene cluster: Hs.258551

    UniProtKB/Swiss-Prot: DNPEP_HUMAN, Q9ULA0
    Tissue specificity: Ubiquitous

        SABiosciences Custom PCR Arrays for DNPEP
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DNPEP

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for DNPEP gene from 9/33 species (see all 33)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Dnpep1 , 5 aspartyl aminopeptidase1, 5 86.46(n)1
    89.89(a)1
      1 (38.71 cM)5
    134371  NM_001110831.11  NP_001104301.11 
     753085655 
    chicken
    (Gallus gallus)
    Aves DNPEP1 aspartyl aminopeptidase 74.8(n)
    78.37(a)
      424200  NM_001012919.1  NP_001012937.1 
    lizard
    (Anolis carolinensis)
    Reptilia DNPEP6
    --
    72(a)
    1 ↔ 1
    1(95472595-95486674)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.208192 Xenopus laevis transcribed sequence with moderate similarity more 81.29(n)    BQ884373.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc559442 hypothetical protein MGC55944 73.41(n)   393122  BC044551.1 
    worm
    (Caenorhabditis elegans)
    Secernentea F01F1.93
    dnpp-11
    Protein DNPP-11 50(a)3
    55.51(n)1
    52.11(a)1
      III(5933767-5935322)3
    1758221  NM_065864.41  NP_498265.11 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes APE4(YHR113W)4
    APE41
    Cytoplasmic aspartyl aminopeptidase that may also function more4
    Ape4p1
    49.41(n)1
    47.14(a)1
      8(336337-337809)4
    8565131, 4  NP_011981.11, 4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT5G601601 aspartyl aminopeptidase 54.24(n)
    52.63(a)
      836138  NM_125409.4  NP_200824.1 
    rice
    (Oryza sativa)
    Liliopsida Os.167102 Oryza sativa (japonica cultivar-group) cDNA clone0 more 74.53(n)    AK071207.1 


    ENSEMBL Gene Tree for DNPEP (if available)
    TreeFam Gene Tree for DNPEP (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/304 NCBI SNPs in DNPEP are shown (see all 304    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1447367851,2
    --220237715(+) AAAGAC/TTGGAA 1 -- ds50010--------
    rs1132777661,2
    --220237784(+) TTTGAC/ATTTTT 1 -- ds50011Minor allele frequency- A:0.50CSA 2
    rs113389071,2
    C,--220237926(+) GCTGA-/GATTAC 1 -- ds50012Minor allele frequency- G:0.00NA CSA 4
    rs75871601,2
    C,A,--220237972(+) TTTAGT/CAGGGA 1 -- ds50015Minor allele frequency- C:0.11NA WA CSA 9
    rs1493173481,2
    --220238017(+) ACTCCC/TGACCT 1 -- ds50010--------
    rs1916889311,2
    --220238032(+) TGATCC/TGCCCA 1 -- ds50010--------
    rs1848993851,2
    --220238136(+) GAGTGC/TGGTGG 1 -- ds50010--------
    rs1893813281,2
    --220238225(+) TACAGA/GTGTGT 1 -- ut310--------
    rs124651341,2
    C,F,H,--220238256(+) tttttG/Atattt 1 -- ut311Minor allele frequency- A:0.06WA 118
    rs1810272381,2
    --220238355(+) ATGCTA/GGGAAT 1 -- ut310--------

    HapMap Linkage Disequilibrium report for DNPEP (220238180 - 220264744 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for DNPEP
         1 CNV: 0030

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    DNPEP for disorders           About GeneDecksing

    OMIM gene information: 611367    OMIM disorders: --

    9 diseases for DNPEP:    About MalaCards
    clear cell renal cell carcinoma    renovascular hypertension    renal cell carcinoma    tonsillitis
    hypertension    carcinoma    tuberculosis    malaria
    mycobacterium tuberculosis


    Export disorders for DNPEP gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for DNPEP gene, integrated from 9 sources (see all 23):
    (articles sorted by number of sources associating them with DNPEP)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Purification, characterization, and cloning of a cytosolic aspartyl aminopeptidase. (PubMed id 9632644)1, 2, 3, 9 Wilk S.... Magnusson R.P. (1998)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. Identification of histidine residues important in the catalysis and structure of aspartyl aminopeptidase. (PubMed id 12413488)1, 9 Wilk S....Magnusson R.P. (2002)
    5. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    6. Structure of human aspartyl aminopeptidase complexed with substrate analogue: insight into catalytic mechanism, substrate specificity and M18 peptidase family. (PubMed id 22720794)2 Chaikuad A.... Yue W.W. (2012)
    7. A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
    8. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    9. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    10. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 23549 HGNC: 2981 AceView: DNPEP Ensembl:ENSG00000123992 euGenes: HUgn23549
    ECgene: DNPEP H-InvDB: DNPEP

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for DNPEP Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for DNPEP gene:
    Search GeneIP for patents involving DNPEP

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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