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Aliases for DNM2 Gene

Aliases for DNM2 Gene

  • Dynamin 2 2 3 5
  • Dynamin II 2 3
  • EC 3.6.5.5 4 63
  • DYN2 3 4
  • Cytoskeletal Protein 2
  • DI-CMTB 3
  • CMTDI1 3
  • CMTDIB 3
  • CMT2M 3
  • DYNII 3
  • LCCS5 3

External Ids for DNM2 Gene

Previous GeneCards Identifiers for DNM2 Gene

  • GC19P010959
  • GC19P011051
  • GC19P010673
  • GC19P010824
  • GC19P010405

Summaries for DNM2 Gene

Entrez Gene Summary for DNM2 Gene

  • Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that stimulates GTPase activity. Five alternatively spliced transcripts encoding different proteins have been described. Additional alternatively spliced transcripts may exist, but their full-length nature has not been determined. [provided by RefSeq, Jun 2010]

GeneCards Summary for DNM2 Gene

DNM2 (Dynamin 2) is a Protein Coding gene. Diseases associated with DNM2 include myopathy, centronuclear and lethal congenital contracture syndrome 5. Among its related pathways are Signaling by GPCR and Metabolism. GO annotations related to this gene include GTP binding and GTPase activity. An important paralog of this gene is MX1.

UniProtKB/Swiss-Prot for DNM2 Gene

  • Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Plays a role in the regulation of neuron morphology, axon growth and formation of neuronal growth cones (By similarity). Plays an important role in vesicular trafficking processes, in particular endocytosis. Involved in cytokinesis.

Tocris Summary for DNM2 Gene

  • GTPases are a group of enzymes that catalyze hydrolysis of the gamma phosphate bond in guanine triphosphate (GTP) to form guanine diphosphate (GDP). Mg2+ ions are essential for catalytic activity. GTPases, often coupled to G proteins, are essential in signal transduction.

Gene Wiki entry for DNM2 Gene

No data available for PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for DNM2 Gene

Genomics for DNM2 Gene

Regulatory Elements for DNM2 Gene

Promoters for DNM2 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around DNM2 on UCSC Golden Path with GeneCards custom track

Transcription factor binding sites by QIAGEN in the DNM2 gene promoter:

Genomic Location for DNM2 Gene

Chromosome:
19
Start:
10,718,053 bp from pter
End:
10,833,488 bp from pter
Size:
115,436 bases
Orientation:
Plus strand

Genomic View for DNM2 Gene

Genes around DNM2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
DNM2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for DNM2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for DNM2 Gene

Proteins for DNM2 Gene

  • Protein details for DNM2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P50570-DYN2_HUMAN
    Recommended name:
    Dynamin-2
    Protein Accession:
    P50570
    Secondary Accessions:
    • A8K1B6
    • E7EV30
    • E9PEQ4
    • K7ESI9
    • Q5I0Y0
    • Q7Z5S3
    • Q9UPH4

    Protein attributes for DNM2 Gene

    Size:
    870 amino acids
    Molecular mass:
    98064 Da
    Quaternary structure:
    • Interacts with MYOF (By similarity). Interacts with CTTN and ACTN1 (By similarity). Interacts with SHANK1, SHANK2, SH3BP4 and NOSTRIN. Interacts with SNX9. Interacts with SNX33 (via SH3 domain). Interacts with MYO1E (via SH3 domain). Interacts with PSTPIP1. Interacts with CTNND2 (PubMed:22022388).
    Miscellaneous:
    • Overexpression of CNM- and CMT-related DNM2 mutants in COS7 cells, whatever the mutated domain, led to a reduction in clathrin-mediated receptor endocytosis associated with MAPK ERK-1 and ERK-2 impairment. The membrane trafficking impairment process may represent a common pathophysiological pathway in the autosomal forms of CNM DNM2-CMT neuropathy.

    Three dimensional structures from OCA and Proteopedia for DNM2 Gene

    Alternative splice isoforms for DNM2 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for DNM2 Gene

Proteomics data for DNM2 Gene at MOPED

Post-translational modifications for DNM2 Gene

  • Phosphorylation at Ser-764 by CDK1 is greatly increased upon mitotic entry. It regulates cytokinesis downstream of calcineurin, and does not affect clathrin-mediated endocytosis. Dephosphorylated by calcineurin/PP2 (By similarity). Phosphorylated on tyrosine residues after activation of SRC (By similarity).
  • Ubiquitination at Lys 393 and Lys 669
  • Modification sites at PhosphoSitePlus

Antibody Products

  • Cell Signaling Technology (CST) Antibodies for DNM2 (DYN2)

Domains & Families for DNM2 Gene

Gene Families for DNM2 Gene

Graphical View of Domain Structure for InterPro Entry

P50570

UniProtKB/Swiss-Prot:

DYN2_HUMAN :
  • Contains 1 dynamin-type G (guanine nucleotide-binding) domain.
  • Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
Domain:
  • Contains 1 dynamin-type G (guanine nucleotide-binding) domain.
  • Contains 1 GED domain.
  • Contains 1 PH domain.
Family:
  • Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
genes like me logo Genes that share domains with DNM2: view

Function for DNM2 Gene

Molecular function for DNM2 Gene

GENATLAS Biochemistry:
dynamin 2,large GTPase,ubiquitously expressed,predominantly in skeletal muscle and heart,potentially involved in the G2/mitosis transition
UniProtKB/Swiss-Prot CatalyticActivity:
GTP + H(2)O = GDP + phosphate.
UniProtKB/Swiss-Prot Function:
Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Plays a role in the regulation of neuron morphology, axon growth and formation of neuronal growth cones (By similarity). Plays an important role in vesicular trafficking processes, in particular endocytosis. Involved in cytokinesis.

Enzyme Numbers (IUBMB) for DNM2 Gene

Gene Ontology (GO) - Molecular Function for DNM2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005525 GTP binding IEA,NAS 7590285
GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding IEA --
genes like me logo Genes that share ontologies with DNM2: view
genes like me logo Genes that share phenotypes with DNM2: view

Human Phenotype Ontology for DNM2 Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for DNM2 Gene

MGI Knock Outs for DNM2:

Animal Model Products

In Situ Assay Products

Flow Cytometry Products

No data available for Transcription Factor Targets and HOMER Transcription for DNM2 Gene

Localization for DNM2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for DNM2 Gene

Cytoplasm. Cytoplasm, cytoskeleton. Cell junction. Membrane, clathrin-coated pit. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density. Cell junction, synapse. Midbody. Note=Colocalizes with CTTN at the basis of filopodia in hippocampus neuron growth zones (By similarity). Microtubule-associated. Also found in the postsynaptic density of neuronal cells. {ECO:0000250 UniProtKB:P39052}.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for DNM2 Gene COMPARTMENTS Subcellular localization image for DNM2 gene
Compartment Confidence
cytoskeleton 5
cytosol 5
extracellular 5
golgi apparatus 5
plasma membrane 5
endosome 3
nucleus 3
endoplasmic reticulum 1
lysosome 1
mitochondrion 1
peroxisome 1
vacuole 1

Gene Ontology (GO) - Cellular Components for DNM2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001917 photoreceptor inner segment IEA --
GO:0005634 nucleus IEA --
GO:0005829 cytosol TAS --
GO:0032587 ruffle membrane IEA --
GO:0045334 clathrin-coated endocytic vesicle IEA --
genes like me logo Genes that share ontologies with DNM2: view

Pathways & Interactions for DNM2 Gene

genes like me logo Genes that share pathways with DNM2: view

SIGNOR curated interactions for DNM2 Gene

Activates:
Inactivates:
Is activated by:
Is inactivated by:

Gene Ontology (GO) - Biological Process for DNM2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000086 G2/M transition of mitotic cell cycle NAS 7590285
GO:0006892 post-Golgi vesicle-mediated transport TAS --
GO:0006898 receptor-mediated endocytosis ISS --
GO:0007165 signal transduction NAS 10893263
GO:0009416 response to light stimulus IEA --
genes like me logo Genes that share ontologies with DNM2: view

Drugs & Compounds for DNM2 Gene

(7) Drugs for DNM2 Gene - From: Novoseek and HMDB

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Guanosine diphosphate Experimental Pharma 0
Guanosine triphosphate Experimental Pharma 0

(13) Additional Compounds for DNM2 Gene - From: HMDB, Tocris, and Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
Phosphate
  • NFB Orthophosphate
  • O-Phosphoric acid
  • Ortho-phosphate
  • Orthophosphate (PO43-)
  • Orthophosphate(3-)
14265-44-2
phosphoric acid
  • Acide phosphorique (FRENCH)
  • Acido fosforico [Italian]
  • Acidum phosphoricum
  • Diphosphate tetrasodium
  • Fosforzuuroplossingen [Dutch]
7664-38-2
Water
  • Dihydrogen oxide
  • Steam
7732-18-5
8-CPT-2Me-cAMP, sodium salt
634207-53-7
8-pCPT-2-O-Me-cAMP-AM
1152197-23-3

(5) Tocris Compounds for DNM2 Gene

Compound Action Cas Number
8-CPT-2Me-cAMP, sodium salt Selective Epac activator 634207-53-7
8-pCPT-2-O-Me-cAMP-AM Selective Epac activator; cell-permeable analog of 8CPT-2Me-cAMP (Cat. No. 1645) 1152197-23-3
Dynamin inhibitory peptide Dynamin inhibitor 251634-21-6
Dynamin inhibitory peptide, myristoylated Cell-permeable dynamin inhibitor 251634-22-7
Dynamin inhibitory peptide, myristoylated (control) Control peptide version of dynamin inhibitory peptide, myristoylated (Cat. No. 1775)
genes like me logo Genes that share compounds with DNM2: view

Transcripts for DNM2 Gene

mRNA/cDNA for DNM2 Gene

(5) REFSEQ mRNAs :
(11) Additional mRNA sequences :
(5) Selected AceView cDNA sequences:
(22) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for DNM2 Gene

Dynamin 2:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for DNM2 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9a · 9b · 9c ^ 10 ^ 11a · 11b ^ 12 ^ 13a · 13b ^ 14a · 14b ^ 15 ^ 16a · 16b ^ 17 ^ 18 ^
SP1: - - - - - - -
SP2: - - -
SP3:
SP4: - - -
SP5:
SP6: -
SP7: -
SP8:
SP9:
SP10:
SP11: -

ExUns: 19a · 19b · 19c ^ 20 ^ 21a · 21b · 21c ^ 22a · 22b ^ 23 ^ 24
SP1: - - - -
SP2: - - - -
SP3: - -
SP4:
SP5:
SP6:
SP7:
SP8:
SP9: -
SP10: -
SP11:

Relevant External Links for DNM2 Gene

GeneLoc Exon Structure for
DNM2
ECgene alternative splicing isoforms for
DNM2

Expression for DNM2 Gene

mRNA expression in normal human tissues for DNM2 Gene

mRNA differential expression in normal tissues according to GTEx for DNM2 Gene

This gene is overexpressed in Whole Blood (x4.8).

Protein differential expression in normal tissues from HIPED for DNM2 Gene

This gene is overexpressed in Lymph node (10.1) and Brain (6.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for DNM2 Gene



SOURCE GeneReport for Unigene cluster for DNM2 Gene Hs.211463

mRNA Expression by UniProt/SwissProt for DNM2 Gene

P50570-DYN2_HUMAN
Tissue specificity: Ubiquitously expressed.
genes like me logo Genes that share expression patterns with DNM2: view

Protein tissue co-expression partners for DNM2 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery for DNM2 Gene

Orthologs for DNM2 Gene

This gene was present in the common ancestor of animals.

Orthologs for DNM2 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia DNM2 35
  • 90.71 (n)
  • 96.18 (a)
DNM2 36
  • 96 (a)
OneToOne
dog
(Canis familiaris)
Mammalia DNM2 35
  • 90.84 (n)
  • 96.54 (a)
DNM2 36
  • 97 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Dnm2 35
  • 88.01 (n)
  • 96.78 (a)
Dnm2 16
Dnm2 36
  • 97 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia DNM2 35
  • 97.42 (n)
  • 97.95 (a)
DNM2 36
  • 100 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Dnm2 35
  • 88.81 (n)
  • 96.67 (a)
oppossum
(Monodelphis domestica)
Mammalia DNM2 36
  • 95 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia DNM2 36
  • 90 (a)
OneToOne
chicken
(Gallus gallus)
Aves DNM2 36
  • 73 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia DNM2 36
  • 93 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia dnm2 35
  • 79.36 (n)
  • 90.97 (a)
zebrafish
(Danio rerio)
Actinopterygii dnm2b 35
  • 77.5 (n)
  • 84.51 (a)
DNM2 (1 of 2) 36
  • 70 (a)
OneToMany
dnm2a 36
  • 88 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta shi 37
  • 68 (a)
worm
(Caenorhabditis elegans)
Secernentea dyn-1 37
  • 67 (a)
Species with no ortholog for DNM2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for DNM2 Gene

ENSEMBL:
Gene Tree for DNM2 (if available)
TreeFam:
Gene Tree for DNM2 (if available)

Paralogs for DNM2 Gene

Paralogs for DNM2 Gene

(5) SIMAP similar genes for DNM2 Gene using alignment to 7 proteins:

Pseudogenes.org Pseudogenes for DNM2 Gene

genes like me logo Genes that share paralogs with DNM2: view

Variants for DNM2 Gene

Sequence variations from dbSNP and Humsavar for DNM2 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs3745674 - 10,783,059(+) CCACC(A/C/T)GGCCT reference, missense
VAR_031962 Myopathy, centronuclear, 1 (CNM1)
VAR_031963 Myopathy, centronuclear, 1 (CNM1)
VAR_031964 Myopathy, centronuclear, 1 (CNM1)
VAR_031965 Myopathy, centronuclear, 1 (CNM1)

Structural Variations from Database of Genomic Variants (DGV) for DNM2 Gene

Variant ID Type Subtype PubMed ID
nsv833745 CNV Loss 17160897
nsv911047 CNV Loss 21882294
nsv833746 CNV Loss 17160897
esv2718170 CNV Deletion 23290073
nsv833748 CNV Loss 17160897
nsv138450 CNV Loss 16902084
nsv911049 CNV Loss 21882294
nsv2416 CNV Insertion 18451855
esv2718171 CNV Deletion 23290073

Variation tolerance for DNM2 Gene

Residual Variation Intolerance Score: 3.88% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.41; 27.65% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for DNM2 Gene

HapMap Linkage Disequilibrium report
DNM2
Human Gene Mutation Database (HGMD)
DNM2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for DNM2 Gene

Disorders for DNM2 Gene

MalaCards: The human disease database

(23) MalaCards diseases for DNM2 Gene - From: OMIM, ClinVar, GeneTests, Orphanet, Swiss-Prot, DISEASES, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
myopathy, centronuclear
  • centronuclear myopathy, autosomal, modifier of
lethal congenital contracture syndrome 5
  • autosomal recessive lethal centronuclear myopathy
charcot-marie-tooth disease, dominant intermediate b
  • charcot-marie-tooth disease, axonal, type 2m
autosomal dominant intermediate charcot-marie-tooth disease type b
  • charcot-marie-tooth disease, dominant intermediate b
autosomal dominant charcot-marie-tooth disease type 2m
  • charcot-marie-tooth disease, dominant intermediate b
- elite association - COSMIC cancer census association via MalaCards
Search DNM2 in MalaCards View complete list of genes associated with diseases

UniProtKB/Swiss-Prot

DYN2_HUMAN
  • Charcot-Marie-Tooth disease 2M (CMT2M) [MIM:606482]: An axonal form of Charcot-Marie-Tooth disease, a disorder of the peripheral nervous system, characterized by progressive weakness and atrophy, initially of the peroneal muscles and later of the distal muscles of the arms. Charcot-Marie-Tooth disease is classified in two main groups on the basis of electrophysiologic properties and histopathology: primary peripheral demyelinating neuropathies (designated CMT1 when they are dominantly inherited) and primary peripheral axonal neuropathies (CMT2). Neuropathies of the CMT2 group are characterized by signs of axonal degeneration in the absence of obvious myelin alterations, normal or slightly reduced nerve conduction velocities, and progressive distal muscle weakness and atrophy. Nerve conduction velocities are normal or slightly reduced. {ECO:0000269 PubMed:17636067, ECO:0000269 PubMed:18560793}. Note=The disease is caused by mutations affecting the gene represented in this entry.
  • Charcot-Marie-Tooth disease, dominant, intermediate type, B (CMTDIB) [MIM:606482]: A form of Charcot-Marie-Tooth disease, a disorder of the peripheral nervous system, characterized by progressive weakness and atrophy, initially of the peroneal muscles and later of the distal muscles of the arms. The dominant intermediate type B is characterized by clinical and pathologic features intermediate between demyelinating and axonal peripheral neuropathies, and motor median nerve conduction velocities ranging from 25 to 45 m/sec. {ECO:0000269 PubMed:15731758}. Note=The disease is caused by mutations affecting the gene represented in this entry.
  • Lethal congenital contracture syndrome 5 (LCCS5) [MIM:615368]: A form of lethal congenital contracture syndrome, an autosomal recessive disorder characterized by degeneration of anterior horn neurons, extreme skeletal muscle atrophy and congenital non-progressive joint contractures. The contractures can involve the upper or lower limbs and/or the vertebral column, leading to various degrees of flexion or extension limitations evident at birth. {ECO:0000269 PubMed:23092955}. Note=The disease is caused by mutations affecting the gene represented in this entry.
  • Myopathy, centronuclear, 1 (CNM1) [MIM:160150]: A congenital muscle disorder characterized by progressive muscular weakness and wasting involving mainly limb girdle, trunk, and neck muscles. It may also affect distal muscles. Weakness may be present during childhood or adolescence or may not become evident until the third decade of life. Ptosis is a frequent clinical feature. The most prominent histopathologic features include high frequency of centrally located nuclei in muscle fibers not secondary to regeneration, radial arrangement of sarcoplasmic strands around the central nuclei, and predominance and hypotrophy of type 1 fibers. {ECO:0000269 PubMed:16227997, ECO:0000269 PubMed:17825552, ECO:0000269 PubMed:17932957, ECO:0000269 PubMed:19122038, ECO:0000269 PubMed:19623537, ECO:0000269 PubMed:19932619, ECO:0000269 PubMed:19932620, ECO:0000269 PubMed:20227276, ECO:0000269 PubMed:22396310}. Note=The disease is caused by mutations affecting the gene represented in this entry.

Relevant External Links for DNM2

Genetic Association Database (GAD)
DNM2
Human Genome Epidemiology (HuGE) Navigator
DNM2
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
DNM2
genes like me logo Genes that share disorders with DNM2: view

No data available for Genatlas for DNM2 Gene

Publications for DNM2 Gene

  1. Isolation of an ubiquitously expressed cDNA encoding human dynamin II, a member of the large GTP-binding protein family. (PMID: 7590285) Diatloff-Zito C. … Merlin G. (Gene 1995) 2 3 4 23 67
  2. Dynamin genes Dnm1 and Dnm2 are located on proximal mouse chromosomes 2 and 9, respectively. (PMID: 9143510) Klocke R. … Jockusch H. (Genomics 1997) 2 3 23
  3. Adult course in dynamin 2 dominant centronuclear myopathy with neonatal onset. (PMID: 19932619) Melberg A. … Laporte J. (Neuromuscul. Disord. 2010) 3 23
  4. Expanding the clinical, pathological and MRI phenotype of DNM2- related centronuclear myopathy. (PMID: 20227276) Susman R.D. … North K.N. (Neuromuscul. Disord. 2010) 3 23
  5. Decrease of dynamin 2 levels in late-onset Alzheimer's disease alters Abeta metabolism. (PMID: 19126407) Kamagata E. … Takeda M. (Biochem. Biophys. Res. Commun. 2009) 3 23

Products for DNM2 Gene

Sources for DNM2 Gene

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