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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

DNASE2B Gene

protein-coding GIFtS: 49
GCID: GC01P084864

deoxyribonuclease II beta

Explore 4 diseases affiliated with
DNASE2B via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Deoxyribonuclease II Beta¹ ² ³		DNase2-Like Acid DNase² ³
DLAD¹ ² ³ ⁵		Deoxyribonuclease-2-Beta¹
Endonuclease DLAD² ³		Lysosomal DNase II²
DNase II Beta² ³		EC 3.1.22.1³
DNase II-Like Acid DNase² ³

External Ids:	HGNC: 28875¹	Entrez Gene: 58511²	Ensembl: ENSG00000137976⁷	OMIM: 608057⁵	UniProtKB: Q8WZ79³

Export aliases for DNASE2B gene to outside databases

Previous GC identifers: GC01P084577 GC01P082974

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for DNASE2B:

The protein encoded by this gene shares considerable sequence similarity to, and is structurally related to DNase II.

The latter is a well characterized endonuclease that catalyzes DNA hydrolysis in the absence of divalent cations at

acidic pH. Unlike DNase II which is ubiquitously expressed, expression of this gene product is restricted to the

salivary gland and lungs. The gene has been localized to chromosome 1p22.3 adjacent (and in opposite orientation) to

the uricase pseudogene. Two transcript variants encoding different isoforms have been described for this gene.

(provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: DNS2B_HUMAN, Q8WZ79

Function: Hydrolyzes DNA under acidic conditions. Does not require divalent cations for activity. Participates in the

degradation of nuclear DNA during lens cell differentiation

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000001.10 NC_018912.1 NT_032977.9

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the DNASE2B gene promoter:
STAT5B Sox5 AML1a Hand1 NRSF form 2 E47
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: DNASE2B promoter sequence

Search SABiosciences Chromatin IP Primers for DNASE2B

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DNASE2B

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p22.3 Ensembl cytogenetic band: 1p31.1 HGNC cytogenetic band: 1p22.3

DNASE2B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DNASE2B gene location

GeneLoc information about chromosome 1 GeneLoc Exon Structure

GeneLoc location for GC01P084864: view genomic region (about GC identifiers)

Start:	84,864,215 bp from pter	End:	84,880,701 bp from pter
Size:	16,487 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: DNS2B_HUMAN, Q8WZ79 (See protein sequence)

Recommended Name: Deoxyribonuclease-2-beta precursor

Size: 361 amino acids; 41713 Da

Subcellular location: Lysosome (Probable)

Sequence caution: Sequence=AAF76893.1; Type=Erroneous initiation;

Secondary accessions: Q5VXD0 Q5VXD1 Q8WZ80 Q9NQW3

Alternative splicing: 2 isoforms: Q8WZ79-1 Q8WZ79-2

Explore the universe of human proteins at neXtProt for DNASE2B: NX_Q8WZ79

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q8WZ79

DNASE2B Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (2 alternative transcripts):

NP_067056.2 NP_490649.1

ENSEMBL proteins:

ENSP00000359699 ENSP00000359696

Human Recombinant Protein Products:

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	Browse Proteins at Uscn

Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005576	extracellular region	IEA	--
GO:0005737	cytoplasm	--	--
GO:0005764	lysosome	IEA	--

DNASE2B for ontologies About GeneDecksing

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	Browse ELISAs and CLIAs at Uscn

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

DNASE2B for domains About GeneDecksing

1 InterPro domain/family:

IPR004947 DNase_II

Graphical View of Domain Structure for InterPro Entry Q8WZ79

ProtoNet protein and cluster: Q8WZ79

1 Blocks protein family: IPB004947 Deoxyribonuclease II

UniProtKB/Swiss-Prot: DNS2B_HUMAN, Q8WZ79

Similarity: Belongs to the DNase II family

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: DNS2B_HUMAN, Q8WZ79

Function: Hydrolyzes DNA under acidic conditions. Does not require divalent cations for activity. Participates in the

degradation of nuclear DNA during lens cell differentiation

Catalytic activity: Endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotide end-products

Enzyme Number (IUBMB): EC 3.1.22.1¹

miRNA Products:		Browse 3'-UTR reporter clones for miRNA target validation Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat DNASE2B
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Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
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Gene Editing
Products:

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Cell Line Products:		GenScript Custom overexpressing Cell Line Services for DNASE2B
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DNASE2B

Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0004520	endodeoxyribonuclease activity	--	--
GO:0004531	deoxyribonuclease II activity	IEA	--

DNASE2B for ontologies About GeneDecksing

2 GenomeRNAi human phenotypes for DNASE2B:

Decreased viability with pacli

Increased gamma-H2AX phosphory

Animal Models:
Mouse knock-out Dnase2b^tm1Osa for DNASE2B
2 MGI mutant phenotypes (inferred from 2 alleles) (MGI details for Dnase2b):

homeostasis/metabolism

vision/eye

DNASE2B for phenotypes About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

Lysosome

Lysosome

1.00

Pathway sources
See GeneCards unified pathways
Show all pathways

1 Kegg Pathway (Kegg details for DNASE2B):

Lysosome

DNASE2B for pathways About GeneDecksing

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for DNASE2B

1 Interacting protein for DNASE2B (Q8WZ79³) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
RBL1	P28749³	I2D: score=1

About this table

Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006259	DNA metabolic process	IEA	--

DNASE2B for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for DNASE2B
Search CenterWatch for drugs/clinical trials and news about DNASE2B / DNS2B

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
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Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for DNASE2B gene (2 alternative transcripts):

NM_021233.2 NM_058248.1

Unigene Cluster for DNASE2B:

Deoxyribonuclease II beta

Hs.129142 [show with all ESTs]

Unigene Representative Sequence: NM_021233

2 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000370665(uc001djt.1) ENST00000370662(uc001dju.1 uc009wch.1)

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Additional cDNA sequence:

AF274571.1 AF333389.1 BC065182.1 BC080621.1 BC126136.1 BC126138.1

3 DOTS entries:

DT.40127696 DT.95364740 DT.91933341

24/34 AceView cDNA sequences (see all 34):

CD635711 NM_021233 CD635709 CD635713 NM_058248 CD635695 CD635715 CD635717

AF333389 CD365107 BC065182 AA988125 AI694455 BX280577 AW295184 BQ681950

AF274571 CD366106 BG761484 AI802154 AI820599 AI420898 BC080621 CD365871

GeneLoc Exon Structure

3 Alternative Splicing Database (ASD) splice patterns (SP) for DNASE2B About this scheme

ExUns:	1	^	2	^	3a	·	3b	·	3c	^	4a	·	4b	^	5	^	6a	·	6b	·	6c
SP1:					-								-
SP2:													-
SP3:

ECgene alternative splicing isoforms for DNASE2B

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

DNASE2B expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --

About this image

DNASE2B expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

2 LifeMap In Vivo Development Anatomical Compartments/Cells

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Spinal Cord

Spinal Ventral Columns

Ventral Spinal Cord Progenitor Cells

Motor Neurons

Spinal Cord

Spinal Ventral Columns

Spinal Cord

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See DNASE2B Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for DNASE2B

SOURCE GeneReport for Unigene cluster: Hs.129142

UniProtKB/Swiss-Prot: DNS2B_HUMAN, Q8WZ79

Tissue specificity: Highly expressed in the eye lens and in salivary gland. Detected at lower levels in lung, prostate

and lymph node. Isoform 2 is lung specific

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In Situ
Assay Products:

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(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for DNASE2B gene from 5/16 species (see all 16) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	DNASE2B¹	deoxyribonuclease II beta	61.03(n) 55.77(a)		424540 NM_001037838.1 NP_001032927.1
lizard (Anolis carolinensis)	Reptilia	DNASE2B⁶	--	52(a)	1 ↔ 1	GL343194.1(9509601-9520906)
zebrafish (Danio rerio)	Actinopterygii	LOC562996¹	deoxyribonuclease-2-beta-like	55.18(n) 48.48(a)		562996 XM_686359.4 XP_691451.4
fruit fly (Drosophila melanogaster)	Insecta	DNaseII⁶	Deoxyribonuclease II	28(a)	possible ortholog	3R(13845097-13846883)
worm (Caenorhabditis elegans)	Secernentea	nuc-1¹	Protein NUC-1	45.86(n) 34.85(a)		181174 NM_077203.4 NP_509604.1

ENSEMBL Gene Tree for DNASE2B (if available)
TreeFam Gene Tree for DNASE2B (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for DNASE2B gene

DNASE2²

1 SIMAP similar gene for DNASE2B using alignment to 3 protein entries: DNS2B_HUMAN (see all proteins):

DNASE2

DNASE2B for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 1 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs189573832^1,2		--	84862217(+)	`GCTGAG/TATTGC`	2	--	us2k¹ int¹		0	--	--	--	--
rs1246331^1,2	C,F,A,	--	84862263(+)	`TCTGTT/GTTTAC`	2	--	int¹ us2k¹		9		WA NA CSA EA	369
rs72714743^1,2	C,F,	--	84862413(+)	`AAAGTG/ACAGTG`	2	--	int¹ us2k¹		3		WA NA EA	358
rs182302554^1,2		--	84862572(+)	`TGCCCC/TGGCTG`	2	--	us2k¹ int¹		0	--	--	--	--
rs187650201^1,2		--	84862626(+)	`CCAAAA/GTTTTG`	2	--	us2k¹ int¹		0	--	--	--	--
rs193149085^1,2		--	84862679(+)	`AAAAAA/TCTTTT`	2	--	us2k¹ int¹		0	--	--	--	--
rs183628304^1,2		--	84862740(+)	`GGAAGA/GAAATA`	2	--	us2k¹ int¹		0	--	--	--	--
rs200867753^1,2		--	84862821(+)	`ATGGA-/TTCCCA`	2	--	int¹ us2k¹		0	--	--	--	--
rs12046192^1,2	C,F,	--	84862923(+)	`GAAAAA/TTATTT`	2	--	int¹ us2k¹		3		WA NA EA	358
rs115427778^1,2	F,	--	84862954(+)	`GCTGTG/CAATCT`	2	--	us2k¹ int¹		1		NA	120

HapMap Linkage Disequilibrium report for DNASE2B (84864215 - 84880701 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for DNASE2B: --

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DNASE2B

DNA2.0 Custom Variant and Variant Library Synthesis for DNASE2B

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

DNASE2B for disorders           About GeneDecksing

OMIM gene information: 608057    OMIM disorders: --

4 diseases for DNASE2B:    About MalaCards

alcohol dependence cataract alcoholism prostatitis

Human Genome Epidemiology (HuGE) Navigator: DNASE2B (2 documents)

Export disorders for DNASE2B gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for DNASE2B gene, integrated from 9 sources (see all 14):
(articles sorted by number of sources associating them with DNASE2B)

Utopia: connect your pdf to the dynamic
world of online information

The cloning, genomic structure, localization, and expression of human deoxyribonuclease IIbeta. (PubMed id 11376952)^{1, 2, 3} Krieser R.J....Eastman A. (2001)
Isolation and characterization of the DLAD/Dlad genes, which lie head-to-head with the genes for urate oxidase. (PubMed id 11700027)^{1, 2, 9} Shiokawa D. and Tanuma S. (2001)
Nuclear cataract caused by a lack of DNA degradation in the mouse eye lens. (PubMed id 12944971)^{1, 2, 9} Nishimoto S....Nagata S. (2003)
A family history of deoxyribonuclease II: surprises from Trichinella spiralis and Burkholderia pseudomallei. (PubMed id 12594037)^{1, 3} MacLea K.S.... Eastman A. (2003)
The proteomic analysis of endogenous FAT10 substrates identifies p62/SQSTM1 as a substrate of FAT10ylation. (PubMed id 22797925)¹ Aichem A....Groettrup M. (2012)
Serum ferritin levels are associated with a distinct p henotype of chronic hepatitis C poorly responding to pegylated interferon-alpha and ribavirin therapy. (PubMed id 22095909)¹ Lange C.M....Bochud P.Y. (2012)
DNase 2 is the main DNA-degrading enzyme of the strat um corneum. (PubMed id 21390259)¹ Fischer H....Eckhart L. (2011)
Investigation of genetic susceptibility factors for h uman longevity - A targeted nonsynonymous SNP study. (PubMed id 20800603)¹ Flachsbart F....Nebel A. (2010)
Genome-Wide Association Study of Alcohol Dependence I mplicates a Region on Chromosome 11. (PubMed id 20201924)¹ Edenberg H.J....Foroud T. (2010)
The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)² Gregory S.G.... Bentley D.R. (2006)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 58511	HGNC: 28875	AceView: DLAD	Ensembl:ENSG00000137976	euGenes: HUgn58511
ECgene: DNASE2B	Kegg: 58511	H-InvDB: DNASE2B

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for DNASE2B	Pharmacogenomics, SNPs, Pathways

Intellectual Property for DNASE2B gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for DNASE2B gene:
Search GeneIP for patents involving DNASE2B

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
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Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DNASE2B

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DNASE2B Gene

deoxyribonuclease II beta

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DNASE2B Gene

deoxyribonuclease II beta

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Genomic Viewsfor DNASE2B gene

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for DNASE2B gene

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for DNASE2B gene

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for DNASE2B gene

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for DNASE2B gene

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for DNASE2B gene

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for DNASE2B gene

Expression
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Orthologs
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Genomic Variants
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Disorders / Diseases
for DNASE2B gene

Publications
for DNASE2B gene

Intellectual Property
for DNASE2B gene

Products
for DNASE2B gene