Aliases for DNALI1 Gene
External Ids for DNALI1 Gene
Previous GeneCards Identifiers for DNALI1 Gene
This gene is the human homolog of the Chlamydomonas inner dynein arm gene, p28. The precise function of this gene is not known, however, it is a potential candidate for immotile cilia syndrome (ICS). Ultrastructural defects of the inner dynein arms are seen in patients with ICS. Immotile mutant strains of Chlamydomonas, a biflagellated algae, exhibit similar defects. [provided by RefSeq, Jul 2008]
GeneCards Summary for DNALI1 Gene
DNALI1 (Dynein, Axonemal, Light Intermediate Chain 1) is a Protein Coding gene. Diseases associated with DNALI1 include primary ciliary dyskinesia. Among its related pathways are Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.. GO annotations related to this gene include microtubule motor activity and dynein heavy chain binding.
UniProtKB/Swiss-Prot for DNALI1 Gene
May play a dynamic role in flagellar motility