Aliases for DNAL4 Gene
External Ids for DNAL4 Gene
Previous GeneCards Identifiers for DNAL4 Gene
This gene encodes an axonemal dynein light chain which functions as a component of the outer dynein arms complex. This complex acts as the molecular motor that provides the force to move cilia in an ATP-dependent manner. The encoded protein is expressed in tissues with motile cilia or flagella and may be involved in the movement of sperm flagella. [provided by RefSeq, Dec 2014]
GeneCards Summary for DNAL4 Gene
DNAL4 (Dynein Axonemal Light Chain 4) is a Protein Coding gene. Diseases associated with DNAL4 include mirror movements 3 and visceral heterotaxy. Among its related pathways are Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. and Interleukin-3, 5 and GM-CSF signaling. GO annotations related to this gene include motor activity. An important paralog of this gene is DYNLL1.
UniProtKB/Swiss-Prot for DNAL4 Gene
Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity (By similarity).