Aliases for DNAL4 Gene
External Ids for DNAL4 Gene
Previous GeneCards Identifiers for DNAL4 Gene
This gene encodes an axonemal dynein light chain which functions as a component of the outer dynein arms complex. This complex acts as the molecular motor that provides the force to move cilia in an ATP-dependent manner. The encoded protein is expressed in tissues with motile cilia or flagella and may be involved in the movement of sperm flagella. [provided by RefSeq, Dec 2014]
GeneCards Summary for DNAL4 Gene
DNAL4 (Dynein, Axonemal, Light Chain 4) is a Protein Coding gene. Diseases associated with DNAL4 include mirror movements 3 and familial congenital mirror movements. Among its related pathways are Signaling by GPCR and Interleukin receptor SHC signaling. GO annotations related to this gene include motor activity. An important paralog of this gene is DYNLL1.
UniProtKB/Swiss-Prot for DNAL4 Gene
Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity (By similarity).