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DNAJC8 Gene

protein-coding   GIFtS: 53
GCID: GC01M028526

DnaJ (Hsp40) Homolog, Subfamily C, Member 8

  Search for DNAJC8
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
DnaJ (Hsp40) Homolog, Subfamily C, Member 81 2
Splicing Protein Spf312 3
SPF312 3
HSPC3312
DnaJ Homolog Subfamily C Member 82

External Ids:    HGNC: 154701   Entrez Gene: 228262   Ensembl: ENSG000001266987   UniProtKB: O759373   

Export aliases for DNAJC8 gene to outside databases

Previous GC identifers: GC01P026900 GC01M027537 GC01M027760 GC01M028131 GC01M028211 GC01M028399 GC01M026783


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for DNAJC8 Gene:
DNAJC8 (DnaJ (Hsp40) homolog, subfamily C, member 8) is a protein-coding gene.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000001.10  NC_018912.2  NT_032977.10  
Regulatory elements:
   Regulatory transcription factor binding sites in the DNAJC8 gene promoter:
         CBF-C   CREB   CBF-B   CBF-A   deltaCREB   HSF2   c-Myb   NF-Y   CBF(2)   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidDNAJC8 promoter sequence
   Search Chromatin IP Primers for DNAJC8

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat DNAJC8


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p35.3   Ensembl cytogenetic band:  1p35.3   HGNC cytogenetic band: 1p35

DNAJC8 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DNAJC8 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M028526:  view genomic region     (about GC identifiers)

Start:
28,525,967 bp from pter      End:
28,559,542 bp from pter
Size:
33,576 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: DNJC8_HUMAN, O75937 (See protein sequence)
Recommended Name: DnaJ homolog subfamily C member 8  
Size: 253 amino acids; 29842 Da
Sequence caution: Sequence=AAC35352.1; Type=Erroneous initiation; Sequence=CAG33181.1; Type=Erroneous initiation;
Secondary accessions: B4DUU4 D3DPM0 Q6IBA4 Q8N4Z5 Q9P051 Q9P067

Explore the universe of human proteins at neXtProt for DNAJC8: NX_O75937

Explore proteomics data for DNAJC8 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys108, Lys210
  • Modification sites at PhosphoSitePlus

  • See DNAJC8 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_055095.2  
    ENSEMBL proteins: 
     ENSP00000474440   ENSP00000263697  
    Reactome Protein details: O75937

    DNAJC8 Human Recombinant Protein Products:

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    Novus Biologicals DNAJC8 Protein
    Novus Biologicals DNAJC8 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for DNAJC8

     
    Search eBioscience for Proteins for DNAJC8 

    DNAJC8 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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    DNAJC8 Assay Products:

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    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for DNAJC8
    Cloud-Clone Corp. CLIAs for DNAJC8
    Search eBioscience for ELISAs for DNAJC8 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    DNAJ: Heat shock proteins / DNAJ (HSP40)

    1 InterPro protein domain:
     IPR001623 DnaJ_domain

    Graphical View of Domain Structure for InterPro Entry O75937

    ProtoNet protein and cluster: O75937

    UniProtKB/Swiss-Prot: DNJC8_HUMAN, O75937
    Similarity: Contains 1 J domain


    Find genes that share domains with DNAJC8           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for DNAJC8
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for DNAJC8

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for DNAJC8
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for DNAJC8

    miRNA
    Products:
        
    miRTarBase miRNAs that target DNAJC8:
    hsa-let-7b-5p (MIRT052102), hsa-mir-185-5p (MIRT045369), hsa-mir-128-3p (MIRT045874), hsa-mir-296-3p (MIRT038453), hsa-mir-375 (MIRT019673)

    Block miRNA regulation of human, mouse, rat DNAJC8 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate DNAJC8 (see all 12):
    hsa-miR-224 hsa-miR-3166 hsa-miR-3664-5p hsa-miR-4282 hsa-miR-3692 hsa-miR-570 hsa-miR-146a* hsa-miR-9
    SwitchGear 3'UTR luciferase reporter plasmidDNAJC8 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for DNAJC8
    Predesigned siRNA for gene silencing in human, mouse, rat DNAJC8

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for DNAJC8

    Clone
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    OriGene clones in human, mouse for DNAJC8 (see all 7)
    OriGene ORF clones in mouse, rat for DNAJC8
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: DNAJC8 (NM_014280)
    Sino Biological Human cDNA Clone for DNAJC8
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for DNAJC8
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DNAJC8

    Cell Line
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    GenScript Custom overexpressing Cell Line Services for DNAJC8
    Browse ESI BIO Cell Lines and PureStem Progenitors for DNAJC8 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DNAJC8


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus4
    cytosol2
    cytoskeleton1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005654nucleoplasm TAS--

    Find genes that share ontologies with DNAJC8           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for DNAJC8 About    
    See pathways by source

    SuperPathContained pathways About
    1mRNA Splicing - Major Pathway
    mRNA Splicing - Major Pathway0.78
    mRNA Splicing0.78
    Processing of Capped Intron-Containing Pre-mRNA0.78
    mRNA processing0.44
    2Gene Expression
    Gene Expression0.40


    Find genes that share SuperPaths with DNAJC8           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 BioSystems Pathway for DNAJC8
        mRNA processing


    1 Reactome Pathway for DNAJC8
        mRNA Splicing - Major Pathway


        Pathway & Disease-focused RT2 Profiler PCR Arrays including DNAJC8: 
              Cellular Stress Responses in human mouse rat
              Heat Shock Proteins & Chaperones in human mouse rat

    Interactions:

        Search GeneGlobe Interaction Network for DNAJC8

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for DNAJC8 (O759372, 3 ENSP000002636974) via UniProtKB, MINT, STRING, and/or I2D (see all 101)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SF3A2Q154282, 3, ENSP000002214944MINT-5205575 I2D: score=2 STRING: ENSP00000221494
    GH1P012413, ENSP000003126734I2D: score=1 STRING: ENSP00000312673
    SRRM1Q8IYB33, ENSP000003262614I2D: score=1 STRING: ENSP00000326261
    SRRM2Q9UQ353, ENSP000003017404I2D: score=1 STRING: ENSP00000301740
    IKBKGQ9Y6K93, ENSP000003586224I2D: score=1 STRING: ENSP00000358622
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000398mRNA splicing, via spliceosome TAS--
    GO:0008380RNA splicing TAS--
    GO:0010467gene expression TAS--

    Find genes that share ontologies with DNAJC8           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for DNAJC8 (DNJC8)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for DNAJC8 gene: 
    NM_014280.2  

    Unigene Cluster for DNAJC8:

    DnaJ (Hsp40) homolog, subfamily C, member 8
    Hs.433540  [show with all ESTs]
    Unigene Representative Sequence: NM_014280
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000603289 ENST00000263697(uc001bpn.3) ENST00000489277(uc001bpo.3)
    ENST00000470967 ENST00000482674 ENST00000488868
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat DNAJC8 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate DNAJC8 (see all 12):
    hsa-miR-224 hsa-miR-3166 hsa-miR-3664-5p hsa-miR-4282 hsa-miR-3692 hsa-miR-570 hsa-miR-146a* hsa-miR-9
    SwitchGear 3'UTR luciferase reporter plasmidDNAJC8 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for DNAJC8
    Predesigned siRNA for gene silencing in human, mouse, rat DNAJC8
    Clone
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    OriGene clones in human, mouse for DNAJC8 (see all 7)
    OriGene ORF clones in mouse, rat for DNAJC8
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: DNAJC8 (NM_014280)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for DNAJC8
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DNAJC8
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for DNAJC8
    OriGene qSTAR qPCR primer pairs in human, mouse for DNAJC8
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat DNAJC8
      QuantiTect SYBR Green Assays in human, mouse, rat DNAJC8
      QuantiFast Probe-based Assays in human, mouse, rat DNAJC8

    Additional mRNA sequence: 

    AF083190.1 AF161433.1 AF161449.1 AK300797.1 BC033159.1 BC040417.1 BX538122.1 CR456900.1 

    Selected DOTS entries (see all 35):

    DT.95160242  DT.95160241  DT.95238376  DT.80101787  DT.86998739  DT.100884540  DT.100884532  DT.100032560 
    DT.100753396  DT.100044919  DT.91773253  DT.100884528  DT.100884537  DT.100884538  DT.101955929  DT.100044922 
    DT.100718974  DT.102829008  DT.95131089  DT.100803176  DT.120746773  DT.121422293  DT.121422468  DT.92407733 

    Selected AceView cDNA sequences (see all 683):

    T34702 CB159797 AF161449 BU151510 BM999508 AI375218 BM988363 AA513669 
    CR607856 AA593068 CA417528 CR614495 CB049335 BM927173 AW517209 AI367107 
    BM663354 BM727259 BF982795 BE504362 AW841416 BM796138 H00472 AI142538 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for DNAJC8 (see all 7)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b · 6c · 6d ^ 7 ^ 8 ^ 9a · 9b ^ 10 ^ 11a · 11b · 11c
    SP1:              -           -           -           -     -     -                                                   
    SP2:                          -           -           -     -     -     -                                             
    SP3:              -           -                                                                                       
    SP4:                          -           -                                                                           
    SP5:              -           -           -                                                                           


    ECgene alternative splicing isoforms for DNAJC8

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    DNAJC8 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCCTAGCCTG
    DNAJC8 Expression
    About this image

    DNAJC8 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    DNAJC8 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.433540
        Pathway & Disease-focused RT2 Profiler PCR Arrays including DNAJC8: 
              Cellular Stress Responses in human mouse rat
              Heat Shock Proteins & Chaperones in human mouse rat

    Primer
    Products:
    OriGene qPCR primer pairs and template standards for DNAJC8
    OriGene qSTAR qPCR primer pairs in human, mouse for DNAJC8
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat DNAJC8
    QuantiTect SYBR Green Assays in human, mouse, rat DNAJC8
    QuantiFast Probe-based Assays in human, mouse, rat DNAJC8
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DNAJC8

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for DNAJC8 gene from Selected species (see all 17)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Dnajc81 , 5 DnaJ (Hsp40) homolog, subfamily C, member 81, 5 90.78(n)1
    99.21(a)1
      4 (65.52 cM)5
    685981  NM_172400.31  NP_765988.21 
     1325355505 
    chicken
    (Gallus gallus)
    Aves DNAJC81 DnaJ (Hsp40) homolog, subfamily C, member 8 83.55(n)
    94.85(a)
      419569  XM_417717.4  XP_417717.4 
    lizard
    (Anolis carolinensis)
    Reptilia DNAJC86
    DnaJ (Hsp40) homolog, subfamily C, member 8
    91(a)
    1 ↔ 1
    GL343743.1(161823-172544)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.246862 Xenopus laevis transcribed sequence with moderate similarity more 78.57(n)    CD301459.1 
    zebrafish
    (Danio rerio)
    Actinopterygii 570409282   -- 75.5(n)   321414  57040928 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG103751 , 3 CG103751 51(a)3
    54.65(n)1
    54.51(a)1
      95B13
    428121  NM_142928.31  NP_651185.11 
    worm
    (Caenorhabditis elegans)
    Secernentea dnj-301 dnj-30 55.12(n)
    48.05(a)
      171833  NM_058629.5  NP_491030.1 


    ENSEMBL Gene Tree for DNAJC8 (if available)
    TreeFam Gene Tree for DNAJC8 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for DNAJC8 gene

    Find genes that share paralogs with DNAJC8           About GenesLikeMe


    Selected Pseudogenes.org Pseudogenes for DNAJC8 (see all 6)
    PGOHUM00000248133 PGOHUM00000234965 PGOHUM00000251060 PGOHUM00000244654 PGOHUM00000237782


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for DNAJC8 (see all 649)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs794461771,2
    C,F--28526412(+) CTGCCT/CTGGTC 1 -- ds50013Minor allele frequency- C:0.08NA WA 240
    rs1808076171,2
    --28526589(+) CATGGA/TGCCTT 1 -- ds50010--------
    rs49083921,2
    F,A,H--28526709(+) CCTTCT/CCACTT 1 -- ds50014Minor allele frequency- C:0.00NS EA 412
    rs1409821871,2
    --28526787(+) TGGACA/GCTTTC 1 -- ds50010--------
    rs1849146341,2
    --28526802(+) ATTACG/TTCATT 1 -- ut310--------
    rs1449169621,2
    --28526858(+) GGATAC/TTGGCA 1 -- ut310--------
    rs1482764601,2
    C--28526913(+) AAATCG/TGCCCT 1 -- ut310--------
    rs1403716141,2
    --28526938(+) TAATTC/TATATT 1 -- ut310--------
    rs10495041,2
    C,F,O,A,H--28527011(-) TTGGCT/CGAACC 1 -- ut3116Minor allele frequency- C:0.34MN NA NS WA CSA EA EU 1295
    rs1901137901,2
    --28527099(+) AAGAAC/TATTAC 1 -- ut310--------

    HapMap Linkage Disequilibrium report for DNAJC8 (28525967 - 28559542 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for DNAJC8:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2674175CNV Deletion23128226
    nsv871151CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing DNAJC8
    DNA2.0 Custom Variant and Variant Library Synthesis for DNAJC8

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

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    Find genes that share disorders with DNAJC8           About GenesLikeMe

    Genetic Association Database (GAD): DNAJC8
    Human Genome Epidemiology (HuGE) Navigator: DNAJC8 (1 document)

    Export disorders for DNAJC8 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

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    PubMed articles for DNAJC8 gene, integrated from 10 sources (see all 33):
    (articles sorted by number of sources associating them with DNAJC8)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    2. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (Nature 2006)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Mammalian HSP40/DNAJ homologs: cloning of novel cDNAs and a proposal for their classification and nomenclature. (PubMed id 11147971)1, 3 Ohtsuka K. and Hata M. (Cell Stress Chaperones 2000)
    5. The protein interaction landscape of the human CMGC kinase group. (PubMed id 23602568)1 Varjosalo M....Gstaiger M. (Cell Rep 2013)
    6. The F-box protein FBXO25 promotes the proteasome-dependent degradation of ELK-1 protein. (PubMed id 23940030)1 Teixeira F.R....Gomes M.D. (J. Biol. Chem. 2013)
    7. The HECT type ubiquitin ligase NEDL2 is degraded by anaphase-promoting complex/cyclosome (APC/C)-Cdh1, and its tight regulation maintains the metaphase to anaphase transition. (PubMed id 24163370)1 Lu L....Zhang L. (J. Biol. Chem. 2013)
    8. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    9. A high-throughput approach for measuring temporal changes in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (Nat. Methods 2012)
    10. A catalogue of putative HIV-1 protease host cell substrates. (PubMed id 22944692)1 Impens F....Gevaert K. (Biol. Chem. 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 22826 HGNC: 15470 AceView: DNAJC8 Ensembl:ENSG00000126698 euGenes: HUgn22826
    ECgene: DNAJC8 H-InvDB: DNAJC8

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for DNAJC8 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for DNAJC8 gene:
    Search GeneIP for patents involving DNAJC8

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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