DNAJC7 Gene
protein-coding GIFtS: 52
GCID: GC17M040128
|
|
DnaJ (Hsp40) homolog, subfamily C, member 7 (Previous symbol: TTC2)
| |
Aliases for DNAJC7 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
| This gene clusters with an RNA gene Subcategory (RNA class): lncRNA
Quality score for the ORGUL clustered with this gene is 3
| Aliases |
|---|
| DnaJ (Hsp40) Homolog, Subfamily C, Member 71 2 | | DJ112 | | TPR21 2 3 5 | | DJC72 | | TTC21 2 3 5 | | DnaJ Homolog Subfamily C Member 72 | | Tetratricopeptide Repeat Protein 22 3 | | Tetratricopeptide Repeat Domain 22 | | TPR Repeat Protein 22 3 | | DANJC75 |
| External Ids: | HGNC: 123921 | Entrez Gene: 72662 | Ensembl: ENSG000001682597 | OMIM: 6019645 | UniProtKB: Q996153 |
|---|
| | ORGUL members: | |
|---|
| NONCODE:n408352 | |
Export aliases for DNAJC7 gene to outside databasesPrevious GC identifers: GC17M039682 GC17M042284 GC17M040037 GC17M040501 GC17M037382 GC17M035893
Summaries for DNAJC7 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for DNAJC7: This gene encodes a member of the DNAJ heat shock protein 40 family of proteins that is characterized by two N-terminaltetratricopeptide repeat domains and a C-terminal DNAJ domain. This protein binds the chaperone proteins heat shockproteins 70 and 90 in an ATP-dependent manner and may function as a co-chaperone. Pseudogenes of this gene are foundon chromosomes 1 and 6. Alternate splicing results in multiple transcript variants.(provided by RefSeq, Oct 2009) UniProtKB/Swiss-Prot: DNJC7_HUMAN, Q99615Function: Acts as co-chaperone regulating the molecular chaperones HSP70 and HSP90 in folding of steroid receptors,such as the glucocorticoid receptor and the progesterone receptor. Proposed to act as a recycling chaperone byfacilitating the return of chaperone substrates to early stages of chaperoning if further folding is required. Invitro, induces ATP-independent dissociation of HSP90 but not of HSP70 from the chaperone-substrate complexes. RecruitsNR1I3 to the cytoplasm (By similarity) Gene Wiki entry for DNAJC7
|
Genomic Views for DNAJC7 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000017.10 NC_018928.1 NT_010783.15
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the DNAJC7 gene promoter: p53 NRSF form 1 CUTL1 NRSF form 2 c-Ets-1 Other transcription factors
Search SABiosciences Chromatin IP Primers for DNAJC7
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DNAJC7 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 17q11.2 Ensembl cytogenetic band: 17q21.2 HGNC cytogenetic band: 17q11.2DNAJC7 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 17 GeneLoc Exon Structure GeneLoc location for GC17M040128: view genomic region
(about GC identifiers)
Start:
|
40,128,439 bp from pter |
End:
|
40,173,394 bp from pter |
Size:
|
44,956 bases |
Orientation:
|
minus strand |
|
Proteins for DNAJC7 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: DNJC7_HUMAN, Q99615 (See
protein sequence)Recommended Name: DnaJ homolog subfamily C member 7 Size: 494 amino acids; 56441 Da
Subunit: Associates with complexes containing chaperones HSP70 and HSP90. Interacts with the GAP domain of NF1.Interacts with HSP90AA1. Interacts with HSPA1A/B; the interaction is enhanced by ATP. Interacts with HSP90AB1.Interacts with PGR. Interacts with RAD9A; the interaction is interrupted by UV and heat shock treatments. Interactswith HUS1 and RAD1. Interacts with NR1I3. The DNAJC7-NR1I3 complex may also include HSP90 (By similarity). Interactswith HSPA8
Subcellular location: Cytoplasm. Nucleus. Cytoplasm, cytoskeleton. Note=Colocalizes with NR1I3 to microtubules (Bysimilarity)
Sequence caution: Sequence=AAB36872.1; Type=Erroneous initiation; Note=Translation N-terminally extended;Sequence=AAH33772.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: Q7Z784Alternative splicing: 2 isoforms: Q99615-1 Q99615-2 Explore the universe of human proteins at neXtProt for DNAJC7: NX_Q99615
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q99615 DNAJC7 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001138238.1 NP_003306.3 ENSEMBL proteins: ENSP00000406463 ENSP00000467702 ENSP00000394327 ENSP00000466114 ENSP00000313311 ENSP00000464993 ENSP00000467477 ENSP00000468805 ENSP00000464756 ENSP00000468102 ENSP00000465340 ENSP00000466748 ENSP00000466877 ENSP00000465228 ENSP00000465399 ENSP00000465140 Human Recombinant Protein Products:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
DNAJC7 for ontologies About GeneDecksing
DNAJC7 Antibody Products: Assay Products for DNAJC7: |
Protein
Domains / Families for DNAJC7 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
DNAJC7 for domains About GeneDecksing
5 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q99615ProtoNet protein and cluster: Q99615 UniProtKB/Swiss-Prot: DNJC7_HUMAN, Q99615Similarity: Contains 1 J domainSimilarity: Contains 9 TPR repeats |
Function for DNAJC7 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Function Summary: UniProtKB/Swiss-Prot: DNJC7_HUMAN, Q99615Function: Acts as co-chaperone regulating the molecular chaperones HSP70 and HSP90 in folding of steroid receptors,such as the glucocorticoid receptor and the progesterone receptor. Proposed to act as a recycling chaperone byfacilitating the return of chaperone substrates to early stages of chaperoning if further folding is required. Invitro, induces ATP-independent dissociation of HSP90 but not of HSP70 from the chaperone-substrate complexes. RecruitsNR1I3 to the cytoplasm (By similarity)
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DNAJC7 (see all 5) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DNAJC7 (see all 5) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): DNAJC7 (NM_003315) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for DNAJC7 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DNAJC7  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DNAJC7 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
DNAJC7 for ontologies About GeneDecksing
2 GenomeRNAi human phenotypes for DNAJC7:
|
Pathways & Interactions for DNAJC7 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for DNAJC7
STRING Interaction
Network Preview (showing 5 interactants - click image to see 18)
 5/37 Interacting proteins for DNAJC7 (Q996151, 2, 3 ENSP000004064634) via UniProtKB, MINT, STRING, and/or I2D (see all 37)About this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table
DNAJC7 for ontologies About GeneDecksing
|
Drugs & Compounds for DNAJC7 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Browse Tocris compounds for DNAJC7 Search CenterWatch for drugs/clinical trials and news about DNAJC7 / DNJC7 
|
Transcripts for DNAJC7 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for DNAJC7 gene (2 alternative transcripts): NM_001144766.2 NM_003315.3 Unigene Cluster for DNAJC7: DnaJ (Hsp40) homolog, subfamily C, member 7 Hs.500156 [show with all ESTs]Unigene Representative Sequence: AK12617918/23 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 23): ENST00000457167(uc002hyo.3 uc002hyp.3 uc010wgc.2) ENST00000587727 ENST00000426588(uc010wgb.2 uc010cxw.3) ENST00000588814 ENST00000316603 ENST00000585693 ENST00000586335 ENST00000590197 ENST00000590847 ENST00000589810 ENST00000588641 ENST00000590348 ENST00000591153 ENST00000589576 ENST00000590774 ENST00000589586 ENST00000585866 ENST00000589773
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DNAJC7 (see all 5) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DNAJC7 (see all 5) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): DNAJC7 (NM_003315) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for DNAJC7 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DNAJC7  |
Additional cDNA sequence: AB209834.1 AK093965.1 AK126179.1 AK291047.1 AK296602.1 AK298860.1 AK308016.1 AK316081.1 AL832812.1 BC003601.1 BC011837.2 BC033772.1 BX647209.1 NR_029431.1 U46571.1 24/33 DOTS entries (see all 33): DT.416333 DT.100699901 DT.100820692 DT.99992907 DT.100683725 DT.100820696 DT.91678481 DT.101977393 DT.407400 DT.92417479 DT.101961705 DT.86999870 DT.101955210 DT.75165174 DT.100820697 DT.102836836 DT.95165897 DT.100820693 DT.40106794 DT.40106795 DT.97854708 DT.120967377 DT.120967402 DT.120967419 24/357 AceView cDNA sequences (see all 357): AI245269 BE222729 BX460774 BM746604 BQ061653 BI962957 BM806093 CB160389 BC003601 AA626252 BX647209 BM456893 BM464293 BX419048 CR622093 BM692686 BQ065889 CR615988 BM468104 U46571 BP360614 AI633507 BM464668 BQ057829 GeneLoc Exon Structure
5 Alternative Splicing Database (ASD) splice patterns (SP) for DNAJC7 About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9a | · | 9b | ^ | 10 | ^ | 11a | · | 11b | ^ | 12a | · | 12b | ^ | 13 | ^ | 14 | |
| SP1: | |   | - |   | - |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP2: | |   | |   | - |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for DNAJC7
|
Expression for DNAJC7 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| DNAJC7 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: AATATGGGTG
About this image See DNAJC7 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for DNAJC7
SOURCE GeneReport for Unigene cluster: Hs.500156 SABiosciences Expression via Pathway-Focused PCR Arrays including DNAJC7:
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DNAJC7 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat DNAJC7 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DNAJC7 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DNAJC7 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DNAJC7 |
Orthologs for DNAJC7 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for DNAJC7 gene from 7/28 species (see all 28) About this table
| Organism |
Taxonomic classification |
Gene |
Description |
Human Similarity |
Orthology Type |
Details |
chicken (Gallus gallus) |
Aves |
DNAJC71 |
DnaJ (Hsp40) homolog, subfamily C, member 7 |
83.13(n) 93.12(a) |
  |
428312 NM_001031502.2 NP_001026673.2 |
lizard (Anolis carolinensis) |
Reptilia |
DNAJC76 |
-- |
91(a) |
1 ↔ 1 |
6(66385364-66401337) |
African clawed frog (Xenopus laevis) |
Amphibia |
Xl.334122 |
Xenopus laevis transcribed sequence with moderate similarity more |
79(n) |
  |
BX847549.1 |
zebrafish (Danio rerio) |
Actinopterygii |
wufa20d062 |
Transcribed sequence with moderate similarity to protein more |
77.27(n) |
  |
BI887624.1 |
fruit fly (Drosophila melanogaster) |
Insecta |
Tpr21 , 3 |
Tetratricopeptide repeat protein 21 |
47(a)3 53.29(n)1 47.19(a)1 |
  |
36A23 349841 NM_078860.21 NP_523584.11 |
thale cress (Arabidopsis thaliana) |
eudicotyledons |
P58IPK1 |
mamallian P58IPK-like protein |
44.47(n) 31.76(a) |
  |
831917 NM_120394.3 NP_195936.1 |
rice (Oryza sativa) |
Liliopsida |
Os02g01953001 |
hypothetical protein |
48.89(n) 36.36(a) |
  |
4328607 NM_001052719.2 NP_001046184.2 |
ENSEMBL Gene Tree for DNAJC7 (if available) TreeFam Gene Tree for DNAJC7 (if available)  |
Paralogs for DNAJC7 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for DNAJC7 gene
- DNAJB42 DNAJC32 DNAJB52 DNAJB132 DNAJB22 DNAJB92 DNAJC112 DNAJB62
- DNAJB12 DNAJB72 DNAJB82
1 SIMAP similar gene for DNAJC7 using alignment to 14 protein entries: DNJC7_HUMAN (see all proteins):DNAJB3
DNAJC7 for paralogs About GeneDecksing
2 Pseudogenes.org Pseudogenes for DNAJC7 PGOHUM00000244053 PGOHUM00000243793
|
Genomic Variants for DNAJC7 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 17 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for DNAJC7 (40128439 - 40173394 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for DNAJC7: --  | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DNAJC7 |
|
Disorders
/ Diseases for DNAJC7 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
DNAJC7 for disorders About GeneDecksing
OMIM gene information: 601964
OMIM disorders: --
3 diseases for DNAJC7: About MalaCardsspinocerebellar ataxia ataxia schizophrenia Export disorders for DNAJC7 gene to outside databases
|
Publications for DNAJC7 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for DNAJC7 gene, integrated from 9 sources (see all 40): (articles sorted by number of sources associating them with DNAJC7) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Identification and characterization of two novel tetratricopeptide repeat-containing genes. (PubMed id 8836031)1, 2, 3, 9 Murthy A.E.... Gusella J.F. (1996)
- The J domain of Tpr2 regulates its interaction with the proapoptotic and cell-cycle checkpoint protein, Rad9. (PubMed id 11573955)1, 2, 9 Xiang S.L....Yamamoto K.C. (2001)
- Role of the cochaperone Tpr2 in Hsp90 chaperoning. (PubMed id 18620420)1, 2 Moffatt N.S.... Toft D. (2008)
- Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. (PubMed id 15592455)1, 2 Rush J.... Comb M.J. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Cofactor Tpr2 combines two TPR domains and a J domain to regulate the Hsp70/Hsp90 chaperone system. (PubMed id 12853476)1, 2 Brychzy A....Obermann W.M. (2003)
- Mammalian HSP40/DNAJ homologs: cloning of novel cDNAs and a proposal for their classification and nomenclature. (PubMed id 11147971)1, 3 Ohtsuka K. and Hata M. (2000)
- Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (2012)
- Protein interaction profiling of the p97 adaptor UBXD1 points to a role for the complex in modulating ERGIC-53 trafficking. (PubMed id 22337587)1 Haines D.S....Deshaies R.J. (2012)
- Functional dissection of lysine deacetylases reveals t hat HDAC1 and p300 regulate AMPK. (PubMed id 22318606)1 Lin Y.Y....Boeke J.D. (2012)
|
External Searches for DNAJC7 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing DNAJC7 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing DNAJC7 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing DNAJC7 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for DNAJC7 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for DNAJC7 gene: Search GeneIP for patents involving DNAJC7
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for DNAJC7 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
|
 | |
 | |
 |
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variant library, vector shuttling | | OriGene Custom Antibody Services for DNAJC7 | | OriGene Custom Protein Services for DNAJC7 | | OriGene Custom Immunoassay Development | | |
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat DNAJC7 | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DNAJC7 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DNAJC7 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DNAJC7 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DNAJC7 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DNAJC7 |
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| | | Search Tocris compounds for DNAJC7 |
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 | | DNAJC7 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DNAJC7 |
|  |  |  | | | ThermoFisher Antibody for DNAJC7 |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DNAJC7 |
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GeneCards Homepage -
Last full update: 18 Mar 2013 -
Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013
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