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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

DNAJC7 Gene

protein-coding   GIFtS: 53
GCID: GC17M040128

DnaJ (Hsp40) Homolog, Subfamily C, Member 7


(Previous symbol: TTC2)
  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
DnaJ (Hsp40) Homolog, Subfamily C, Member 71 2     DJ112
TTC21 2 3 5     DJC72
TPR22 3 5     DnaJ Homolog Subfamily C Member 72
Tetratricopeptide Repeat Protein 22 3     Tetratricopeptide Repeat Domain 22
TPR Repeat Protein 22 3     DANJC75

External Ids:    HGNC: 123921   Entrez Gene: 72662   Ensembl: ENSG000001682597   OMIM: 6019645   UniProtKB: Q996153   

Export aliases for DNAJC7 gene to outside databases

Previous GC identifers: GC17M039682 GC17M042284 GC17M040037 GC17M040501 GC17M037382 GC17M035893


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for DNAJC7 Gene:
This gene encodes a member of the DNAJ heat shock protein 40 family of proteins that is characterized by two
N-terminal tetratricopeptide repeat domains and a C-terminal DNAJ domain. This protein binds the chaperone
proteins heat shock proteins 70 and 90 in an ATP-dependent manner and may function as a co-chaperone. Pseudogenes
of this gene are found on chromosomes 1 and 6. Alternate splicing results in multiple transcript
variants.(provided by RefSeq, Oct 2009)

GeneCards Summary for DNAJC7 Gene: 
DNAJC7 (DnaJ (Hsp40) homolog, subfamily C, member 7) is a protein-coding gene. Diseases associated with DNAJC7 include schizophrenia. GO annotations related to this gene include unfolded protein binding and heat shock protein binding. An important paralog of this gene is DNAJC3.

UniProtKB/Swiss-Prot: DNJC7_HUMAN, Q99615
Function: Acts as co-chaperone regulating the molecular chaperones HSP70 and HSP90 in folding of steroid
receptors, such as the glucocorticoid receptor and the progesterone receptor. Proposed to act as a recycling
chaperone by facilitating the return of chaperone substrates to early stages of chaperoning if further folding is
required. In vitro, induces ATP-independent dissociation of HSP90 but not of HSP70 from the chaperone-substrate
complexes. Recruits NR1I3 to the cytoplasm (By similarity)

Gene Wiki entry for DNAJC7 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000017.10  NC_018928.2  NT_010783.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the DNAJC7 gene promoter:
         p53   NRSF form 1   CUTL1   NRSF form 2   c-Ets-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidDNAJC7 promoter sequence
   Search SABiosciences Chromatin IP Primers for DNAJC7

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DNAJC7


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q11.2   Ensembl cytogenetic band:  17q21.2   HGNC cytogenetic band: 17q11.2

DNAJC7 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DNAJC7 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M040128:  view genomic region     (about GC identifiers)

Start:
40,128,439 bp from pter      End:
40,173,394 bp from pter
Size:
44,956 bases      Orientation:
minus strand

1 alternative location:
Chr17-,NW_003571052 263,063-304,339     

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: DNJC7_HUMAN, Q99615 (See protein sequence)
Recommended Name: DnaJ homolog subfamily C member 7  
Size: 494 amino acids; 56441 Da
Subunit: Associates with complexes containing chaperones HSP70 and HSP90. Interacts with the GAP domain of NF1.
Interacts with HSP90AA1. Interacts with HSPA1A/B; the interaction is enhanced by ATP. Interacts with HSP90AB1.
Interacts with PGR. Interacts with RAD9A; the interaction is interrupted by UV and heat shock treatments.
Interacts with HUS1 and RAD1. Interacts with NR1I3. The DNAJC7-NR1I3 complex may also include HSP90 (By
similarity). Interacts with HSPA8
Subcellular location: Cytoplasm. Nucleus. Cytoplasm, cytoskeleton. Note=Colocalizes with NR1I3 to microtubules (By
similarity)
Sequence caution: Sequence=AAB36872.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=AAH33772.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: Q7Z784
Alternative splicing: 2 isoforms:  Q99615-1   Q99615-2   

Explore the universe of human proteins at neXtProt for DNAJC7: NX_Q99615

Explore proteomics data for DNAJC7 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q99615

  • DNAJC7 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    DNAJC7 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001138238.1  NP_003306.3  

    ENSEMBL proteins: 
     ENSP00000406463   ENSP00000467702   ENSP00000394327   ENSP00000466114   ENSP00000313311  
     ENSP00000464993   ENSP00000467477   ENSP00000468805   ENSP00000464756   ENSP00000468102  
     ENSP00000465340   ENSP00000466748   ENSP00000466877   ENSP00000465228   ENSP00000465399  
     ENSP00000465140  

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    Cloud-Clone Corp. Proteins for DNAJC7 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730NOT nucleolus IDA--
    GO:0005737cytoplasm IDA--
    GO:0005856cytoskeleton IEA--

    DNAJC7 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    DNAJ: Heat shock proteins / DNAJ (HSP40)
    TTC: Tetratricopeptide (TTC) repeat domain containing

    5 InterPro protein domains:
     IPR011990 TPR-like_helical
     IPR001440 TPR-1
     IPR001623 DnaJ_domain
     IPR013026 TPR-contain_dom
     IPR019734 TPR_repeat

    Graphical View of Domain Structure for InterPro Entry Q99615

    ProtoNet protein and cluster: Q99615

    UniProtKB/Swiss-Prot: DNJC7_HUMAN, Q99615
    Similarity: Contains 1 J domain
    Similarity: Contains 9 TPR repeats


    DNAJC7 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: DNJC7_HUMAN, Q99615
    Function: Acts as co-chaperone regulating the molecular chaperones HSP70 and HSP90 in folding of steroid
    receptors, such as the glucocorticoid receptor and the progesterone receptor. Proposed to act as a recycling
    chaperone by facilitating the return of chaperone substrates to early stages of chaperoning if further folding is
    required. In vitro, induces ATP-independent dissociation of HSP90 but not of HSP70 from the chaperone-substrate
    complexes. Recruits NR1I3 to the cytoplasm (By similarity)

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
    GO:0031072heat shock protein binding IPI12853476
         
    DNAJC7 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for DNAJC7:
     Increased cell death HMECs cel  Increased cell death in breast 

         1 MGI phenotypic allele for Dnajc7 (no phenotypes)

    DNAJC7 for phenotypes           About GeneDecksing

    Animal Models:
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    SwitchGear 3'UTR luciferase reporter plasmidDNAJC7 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for DNAJC7

    STRING Interaction Network Preview (showing 5 interactants - click image to see 18)

    5/37 Interacting proteins for DNAJC7 (Q996151, 2, 3 ENSP000004064634) via UniProtKB, MINT, STRING, and/or I2D (see all 37)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SMAD2Q157962, 3, ENSP000002621604MINT-61584 I2D: score=3 STRING: ENSP00000262160
    TAB1Q157502, 3, ENSP000002161604MINT-49180 I2D: score=2 STRING: ENSP00000216160
    MAP3K3Q997592, 3MINT-48516 I2D: score=2 
    SMAD9O151982, 3, ENSP000003691544MINT-62135 I2D: score=3 STRING: ENSP00000369154
    RAD9AQ996383, ENSP000003113604I2D: score=4 STRING: ENSP00000311360
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006457protein folding TAS8836031
    GO:0070389chaperone cofactor-dependent protein refolding IDA12853476

    DNAJC7 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for DNAJC7 (DNJC7)

    Search CenterWatch for drugs/clinical trials and news about DNAJC7 / DNJC7

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for DNAJC7 gene (2 alternative transcripts): 
    NM_001144766.2  NM_003315.3  

    Unigene Cluster for DNAJC7:

    DnaJ (Hsp40) homolog, subfamily C, member 7
    Hs.500156  [show with all ESTs]
    Unigene Representative Sequence: AK126179
    18/23 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 23):
    ENST00000457167(uc002hyo.3 uc002hyp.3 uc010wgc.2) ENST00000587727
    ENST00000426588(uc010wgb.2 uc010cxw.3) ENST00000588814 ENST00000316603
    ENST00000585693 ENST00000586335 ENST00000590197 ENST00000590847 ENST00000589810
    ENST00000588641 ENST00000590348 ENST00000591153 ENST00000589576 ENST00000590774
    ENST00000589586 ENST00000585866 ENST00000589773
    miRNA
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    3 QIAGEN miScript miRNA Assays for microRNAs that regulate DNAJC7:
    hsa-miR-142-5p hsa-miR-513b hsa-miR-561
    SwitchGear 3'UTR luciferase reporter plasmidDNAJC7 3' UTR sequence
    Inhib. RNA
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    Additional mRNA sequence: 

    AB209834.1 AK126179.1 AK291047.1 AK296602.1 AK298860.1 AK308016.1 AK316081.1 AL832812.1 
    BC003601.1 BC011837.2 BC033772.1 BX647209.1 NR_029431.1 U46571.1 

    24/30 DOTS entries (see all 30):

    DT.416333  DT.100699901  DT.100820692  DT.100683725  DT.99992907  DT.100820696  DT.91678481  DT.101977393 
    DT.101955210  DT.75165174  DT.407400  DT.100820697  DT.102836836  DT.95165897  DT.100820693  DT.101961705 
    DT.40106795  DT.97854708  DT.120967377  DT.120967402  DT.120967436  DT.120967546  DT.100809708  DT.120967419 

    24/357 AceView cDNA sequences (see all 357):

    BM468605 AL533843 BP337428 BX345378 BI966782 BM665364 BM796128 AL534086 
    AA729887 AA351967 CR600431 BE794236 BQ953471 AA639418 AA664170 BM806089 
    BM825460 BP372220 BU687415 BP350932 BM697879 CB160389 BC003601 BX647209 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for DNAJC7    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9a · 9b ^ 10 ^ 11a · 11b ^ 12a · 12b ^ 13 ^ 14
    SP1:        -     -           -                                                                           
    SP2:              -           -                                                                           
    SP3:                                                                                      -               
    SP4:                                                                    -                                 
    SP5:                    -                                                                                 


    ECgene alternative splicing isoforms for DNAJC7

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    DNAJC7 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AATATGGGTG
    DNAJC7 Expression
    About this image


    See DNAJC7 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for DNAJC7

    SOURCE GeneReport for Unigene cluster: Hs.500156
        SABiosciences Expression via Pathway-Focused PCR Arrays including DNAJC7: 
              Cellular Stress Responses in human mouse rat
              Heat Shock Proteins & Chaperones in human mouse rat

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DNAJC7

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for DNAJC7 gene from 9/21 species (see all 21)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Dnajc71 , 5 DnaJ (Hsp40) homolog, subfamily C, member 71, 5 91.63(n)1
    97.17(a)1
      11 (63.47 cM)5
    563541  NM_019795.41  NP_062769.21 
     1005828185 
    chicken
    (Gallus gallus)
    Aves DNAJC71 DnaJ (Hsp40) homolog, subfamily C, member 7 83.13(n)
    93.12(a)
      428312  NM_001031502.2  NP_001026673.2 
    lizard
    (Anolis carolinensis)
    Reptilia DNAJC76
    Uncharacterized protein
    86(a)
    1 ↔ 1
    6(66365565-66401337)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.334122 Xenopus laevis transcribed sequence with moderate similarity more 79(n)    BX847549.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufa20d062 Transcribed sequence with moderate similarity to protein more 77.27(n)    BI887624.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Tpr21 , 3 Tetratricopeptide repeat protein 21 47(a)3
    53.29(n)1
    47.19(a)1
      36A23
    349841  NM_078860.21  NP_523584.11 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes JEM16
    DnaJ-like chaperone required for nuclear membrane ...
    10(a)
    1 → many
    X(303181-305118)
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons P58IPK1 mamallian P58IPK-like protein 44.47(n)
    31.76(a)
      831917  NM_120394.3  NP_195936.1 
    rice
    (Oryza sativa)
    Liliopsida Os02g01953001 hypothetical protein 48.89(n)
    36.36(a)
      4328607  NM_001052719.2  NP_001046184.2 


    ENSEMBL Gene Tree for DNAJC7 (if available)
    TreeFam Gene Tree for DNAJC7 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for DNAJC7 gene
    DNAJC32  
    1 SIMAP similar gene for DNAJC7 using alignment to 14 protein entries:     DNJC7_HUMAN (see all proteins):
    DNAJB3

    DNAJC7 for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for DNAJC7
    PGOHUM00000244053 PGOHUM00000243793


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/644 SNPs in DNAJC7 are shown (see all 644)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1142717591,2
    C,F--40130584(+) CCTACT/CTAAAA 3 -- int11Minor allele frequency- C:0.18WA 118
    rs2004203381,2
    --40130631(+) CCAGC-/ACTTTG 3 -- int10--------
    rs1881941091,2
    C--40130775(+) TGCCTA/GTAGTC 3 -- int10--------
    rs2005760581,2
    C--40130792(+) ACTTGA/GGAGGC 3 -- int10--------
    rs1929555671,2
    --40130823(+) AACCCA/GGGAGG 3 -- int10--------
    rs1843099291,2
    C--40130923(+) CACTAC/GTTTTT 3 -- int10--------
    rs1894737521,2
    --40130980(+) TTGTGA/GTGAAC 3 -- int10--------
    rs1817382041,2
    --40131267(+) CAGGAC/GAATTT 3 -- int10--------
    rs2013507201,2
    --40131370(+) ACAAC-/AAAAAA 3 -- int10--------
    rs1837097141,2
    --40131373(+) AACAAA/CAAAAA 3 -- int10--------

    HapMap Linkage Disequilibrium report for DNAJC7 (40128439 - 40173394 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for DNAJC7:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv509658CNV Insertion20534489
    nsv908239CNV Gain21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 601964    OMIM disorders: --

    2 diseases for DNAJC7:    About MalaCards
    schizophrenia    


    DNAJC7 for disorders           About GeneDecksing


    Export disorders for DNAJC7 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for DNAJC7 gene, integrated from 9 sources (see all 47):
    (articles sorted by number of sources associating them with DNAJC7)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification and characterization of two novel tetratricopeptide repeat-containing genes. (PubMed id 8836031)1, 2, 3, 9 Murthy A.E.... Gusella J.F. (1996)
    2. The J domain of Tpr2 regulates its interaction with the proapoptotic and cell-cycle checkpoint protein, Rad9. (PubMed id 11573955)1, 2, 9 Xiang S.L....Yamamoto K.C. (2001)
    3. Role of the cochaperone Tpr2 in Hsp90 chaperoning. (PubMed id 18620420)1, 2 Moffatt N.S.... Toft D. (2008)
    4. Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. (PubMed id 15592455)1, 2 Rush J.... Comb M.J. (2005)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. Cofactor Tpr2 combines two TPR domains and a J domain to regulate the Hsp70/Hsp90 chaperone system. (PubMed id 12853476)1, 2 Brychzy A....Obermann W.M. (2003)
    7. Mammalian HSP40/DNAJ homologs: cloning of novel cDNAs and a proposal for their classification and nomenclature. (PubMed id 11147971)1, 3 Ohtsuka K. and Hata M. (2000)
    8. Specific interaction of the 70-kDa heat shock cognate protein with the tetratricopeptide repeats. (PubMed id 10567422)1, 2 Liu F.H.... Wang C. (1999)
    9. Interlaboratory reproducibility of large-scale human p rotein-complex analysis by standardized AP-MS. (PubMed id 23455922)1 Varjosalo M....Superti-Furga G. (2013)
    10. Co-chaperon DnaJC7/TPR2 enhances p53 stability and act ivity through blocking the complex formation between p53 and MDM2. (PubMed id 23261415)1 Kubo N....Ozaki T. (2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 7266 HGNC: 12392 AceView: DNAJC7 Ensembl:ENSG00000168259 euGenes: HUgn7266
    ECgene: DNAJC7 H-InvDB: DNAJC7

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for DNAJC7 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for DNAJC7 gene:
    Search GeneIP for patents involving DNAJC7

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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