DNAJC5G Gene
protein-coding GIFtS: 44
GCID: GC02P027498
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DnaJ (Hsp40) homolog, subfamily C, member 5 gamma
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Aliases
for DNAJC5G gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| DnaJ (Hsp40) Homolog, Subfamily C, Member 5 Gamma1 2 | | DnaJ Homolog Subfamily C Member 5G2 | | CSP-Gamma1 | | Gamma Cysteine String Protein2 | | Cysteine String Protein-Gamma2 3 | | Gamma-CSP1 | | FLJ404171 | | Gamma-Cysteine String Protein2 |
Export aliases for DNAJC5G gene to outside databasesPrevious GC identifers: GC02P027473 GC02P027412 GC02P027239 |
Summaries
for DNAJC5G gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for DNAJC5G gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000002.11 NC_018913.1 NT_022184.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the DNAJC5G gene promoter:
NF-1 Bach2 POU3F2 (N-Oct-5a) Nkx2-5 POU3F2 LCR-F1 E47 Arnt CREB deltaCREB
Other transcription factors
Search SABiosciences Chromatin IP Primers for DNAJC5G
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DNAJC5G |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 2p23.3 Ensembl cytogenetic band: 2p23.3 HGNC cytogenetic band: 2p23DNAJC5G Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 2 GeneLoc Exon Structure GeneLoc location for GC02P027498: view genomic region
(about GC identifiers)
Start:
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27,498,289 bp from pter |
End:
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27,504,367 bp from pter |
Size:
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6,079 bases |
Orientation:
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plus strand |
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Proteins
for DNAJC5G gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: DNJ5G_HUMAN, Q8N7S2 (See
protein sequence)Recommended Name: DnaJ homolog subfamily C member 5G Size: 189 amino acids; 21433 Da
Subcellular location: Membrane; Lipid-anchor (By similarity)
Secondary accessions: Q53SY5 Q8IYQ4 Q96RJ8Explore the universe of human proteins at neXtProt for DNAJC5G: NX_Q8N7S2
Post-translational modifications:
Palmitoylated (By similarity)1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8N7S2
DNAJC5G Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_775921.1
ENSEMBL proteins: ENSP00000296097 ENSP00000400382 ENSP00000384305 ENSP00000385829 ENSP00000385533
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0016020 | membrane |
IEA | -- |
DNAJC5G for ontologies About GeneDecksing
DNAJC5G Antibody Products:
Assay Products for DNAJC5G: |
Protein
Domains /
Families
for DNAJC5G gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
DNAJC5G for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q8N7S2ProtoNet protein and cluster: Q8N7S2 UniProtKB/Swiss-Prot: DNJ5G_HUMAN, Q8N7S2Similarity: Contains 1 J domain |
Function
for DNAJC5G gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DNAJC5G (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DNAJC5G
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: DNAJC5G (NM_173650) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for DNAJC5G | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DNAJC5G |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DNAJC5G |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0031072 | heat shock protein binding |
IEA | -- | | GO:0051082 | unfolded protein binding |
IEA | -- |
DNAJC5G for ontologies About GeneDecksing
2 GenomeRNAi human phenotypes for DNAJC5G:
Animal Models:
1 MGI phenotypic allele  for Dnajc5g (no phenotypes)
DNAJC5G for phenotypes About GeneDecksing
|
Pathways & Interactions
for DNAJC5G gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Protein processing in endoplasmic reticulum | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 
Kegg Pathway (Kegg details for DNAJC5G):
DNAJC5G for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for DNAJC5G
STRING Interaction
Network Preview (showing 5 interactants - click image to see 11)
5/11 Interacting proteins for DNAJC5G (ENSP000002960974) via UniProtKB, MINT, STRING, and/or I2D (see all 11)About this table
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006457 | protein folding |
IEA | -- |
DNAJC5G for ontologies About GeneDecksing
|
Drugs & Compounds
for DNAJC5G gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for DNAJC5G
Search CenterWatch for drugs/clinical trials and news about DNAJC5G / DNJ5G
|
Transcripts
for DNAJC5G gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for DNAJC5G gene: NM_173650.1 Unigene Cluster for DNAJC5G: DnaJ (Hsp40) homolog, subfamily C, member 5 gamma Hs.116303 [show with all ESTs]Unigene Representative Sequence: NM_1736506 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000296097(uc002rjl.1 uc010yli.1) ENST00000420191 ENST00000402462(uc002rjm.1)
ENST00000404433 ENST00000406962 ENST00000460358
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DNAJC5G (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DNAJC5G
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: DNAJC5G (NM_173650) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for DNAJC5G | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DNAJC5G |
Additional cDNA sequence: AF368277.1 AK097736.1 AK302239.1 BC035194.2 4 DOTS entries: DT.97824169 DT.100019099 DT.100744717 DT.91740278 15 AceView cDNA sequences: NM_173650 AK097736 AF368277 BI755946 BC035194 CD654578 BX492846 BX280646 AI183575 AA629078 AI040950 BF376675 BI459532 BF376661 BF511649
GeneLoc Exon Structure
2 Alternative Splicing Database (ASD) splice patterns (SP) for DNAJC5G About this scheme
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 |
|---|
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| SP1: | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | |
ECgene alternative splicing isoforms for DNAJC5G
|
Expression
for DNAJC5G gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| DNAJC5G expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See DNAJC5G Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for DNAJC5G
SOURCE GeneReport for Unigene cluster: Hs.116303
UniProtKB/Swiss-Prot: DNJ5G_HUMAN, Q8N7S2Tissue specificity: Testis specific
SABiosciences Expression via Pathway-Focused PCR Array including DNAJC5G:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DNAJC5G
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat DNAJC5G | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DNAJC5G | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DNAJC5G | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DNAJC5G |
Orthologs
for DNAJC5G gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for DNAJC5G gene from 3/19 species (see all 19) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
zebrafish
(Danio rerio) |
Actinopterygii |
dnajc5ga6dnajc5gb6 |
DnaJ (Hsp40) homolog, subfamily C, member 5 gamma ...DnaJ (Hsp40) homolog, subfamily C, member 5 gamma ... |
38(a)38(a) |
1 ↔ many1 ↔ many |
20(38788662-38812050) 17(6253923-6272240) |
fruit fly
(Drosophila melanogaster) |
Insecta |
Csp6DnaJ-H6 |
DnaJ homolog |
33(a)10(a) |
1 ↔ manypossible ortholog |
3L(22260361-22266845) 2L(13163209-13166072) |
worm
(Caenorhabditis elegans) |
Secernentea |
dnj-146 |
DNaJ domain (prokaryotic heat shock protein) famil... |
17(a) |
possible ortholog |
X(4709838-4711715) |
ENSEMBL Gene Tree for DNAJC5G (if available)
TreeFam Gene Tree for DNAJC5G (if available) |
Paralogs
for DNAJC5G gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for DNAJC5G gene
- DNAJC5B2 DNAJC52
11 SIMAP similar genes for DNAJC5G using alignment to 4 protein entries: DNJ5G_HUMAN (see all proteins):DNAJB6 DKFZp761N1221 DNAJB4 DNAJB5 DNAJC17 FLJ00095
DNAJC5B DNAJC5 DNAJB3 DNAJC24 ZCSL3
DNAJC5G for paralogs About GeneDecksing
|
Genomic Variants
for DNAJC5G gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 2 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for DNAJC5G (27498289 - 27504367 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for DNAJC5G: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DNAJC5G |
|
Disorders
/ Diseases
for DNAJC5G gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
 DNAJC5G for disorders About MalaCards
DNAJC5G for disorders About GeneDecksing
OMIM gene information: 613946
OMIM disorders: --
Export disorders for DNAJC5G gene to outside databases
|
Publications
for DNAJC5G gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for DNAJC5G gene integrated from 9 sources:
(articles sorted by number of sources associating them with DNAJC5G) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)2 Hillier L.W....Wilson R.K. (2005)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for DNAJC5G gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing DNAJC5G gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing DNAJC5G gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing DNAJC5G gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for DNAJC5G | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for DNAJC5G gene:
Search GeneIP for patents involving DNAJC5G
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for DNAJC5G gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for DNAJC5G | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DNAJC5G | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DNAJC5G | | | OriGene Protein Over-expression Lysate for DNAJC5G | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for DNAJC5G | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DNAJC5G | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DNAJC5G | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat DNAJC5G | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DNAJC5G | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DNAJC5G | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DNAJC5G | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DNAJC5G | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DNAJC5G |
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| |  |  |  |  | | | | |
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DNAJC5G |
|  |  |  | | | | Search ThermoFisher Antibodies for DNAJC5G |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DNAJC5G |
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