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Aliases for DNAJC5G Gene

Aliases for DNAJC5G Gene

  • DnaJ Heat Shock Protein Family (Hsp40) Member C5 Gamma 2 3 5
  • DnaJ (Hsp40) Homolog, Subfamily C, Member 5 Gamma 2 3
  • Cysteine String Protein-Gamma 3 4
  • CSP-Gamma 3 4
  • DnaJ Homolog Subfamily C Member 5G 3
  • Gamma-Cysteine String Protein 3
  • Gamma-CSP 3

External Ids for DNAJC5G Gene

Previous GeneCards Identifiers for DNAJC5G Gene

  • GC02P027473
  • GC02P027412
  • GC02P027498

Summaries for DNAJC5G Gene

GeneCards Summary for DNAJC5G Gene

DNAJC5G (DnaJ Heat Shock Protein Family (Hsp40) Member C5 Gamma) is a Protein Coding gene. Among its related pathways are Protein processing in endoplasmic reticulum. An important paralog of this gene is DNAJC5.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for DNAJC5G Gene

Genomics for DNAJC5G Gene

Regulatory Elements for DNAJC5G Gene

Enhancers for DNAJC5G Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around DNAJC5G on UCSC Golden Path with GeneCards custom track

Genomic Location for DNAJC5G Gene

Chromosome:
2
Start:
27,275,421 bp from pter
End:
27,281,499 bp from pter
Size:
6,079 bases
Orientation:
Plus strand

Genomic View for DNAJC5G Gene

Genes around DNAJC5G on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
DNAJC5G Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for DNAJC5G Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for DNAJC5G Gene

Proteins for DNAJC5G Gene

  • Protein details for DNAJC5G Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N7S2-DNJ5G_HUMAN
    Recommended name:
    DnaJ homolog subfamily C member 5G
    Protein Accession:
    Q8N7S2
    Secondary Accessions:
    • B4DY29
    • Q53SY5
    • Q8IYQ4
    • Q96RJ8

    Protein attributes for DNAJC5G Gene

    Size:
    189 amino acids
    Molecular mass:
    21433 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for DNAJC5G Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for DNAJC5G Gene

Post-translational modifications for DNAJC5G Gene

Other Protein References for DNAJC5G Gene

No data available for DME Specific Peptides for DNAJC5G Gene

Domains & Families for DNAJC5G Gene

Gene Families for DNAJC5G Gene

Protein Domains for DNAJC5G Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for DNAJC5G Gene

Graphical View of Domain Structure for InterPro Entry

Q8N7S2

UniProtKB/Swiss-Prot:

DNJ5G_HUMAN :
  • Contains 1 J domain.
Domain:
  • Contains 1 J domain.
genes like me logo Genes that share domains with DNAJC5G: view

Function for DNAJC5G Gene

genes like me logo Genes that share phenotypes with DNAJC5G: view

Animal Models for DNAJC5G Gene

MGI Knock Outs for DNAJC5G:

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for DNAJC5G Gene

Localization for DNAJC5G Gene

Subcellular locations from UniProtKB/Swiss-Prot for DNAJC5G Gene

Membrane; Lipid-anchor.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for DNAJC5G Gene COMPARTMENTS Subcellular localization image for DNAJC5G gene
Compartment Confidence
cytosol 3
extracellular 1
nucleus 1
plasma membrane 1

Gene Ontology (GO) - Cellular Components for DNAJC5G Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016020 membrane IEA --
genes like me logo Genes that share ontologies with DNAJC5G: view

Pathways & Interactions for DNAJC5G Gene

genes like me logo Genes that share pathways with DNAJC5G: view

Pathways by source for DNAJC5G Gene

1 KEGG pathway for DNAJC5G Gene

Interacting Proteins for DNAJC5G Gene

Gene Ontology (GO) - Biological Process for DNAJC5G Gene

None

No data available for SIGNOR curated interactions for DNAJC5G Gene

Drugs & Compounds for DNAJC5G Gene

No Compound Related Data Available

Transcripts for DNAJC5G Gene

mRNA/cDNA for DNAJC5G Gene

Unigene Clusters for DNAJC5G Gene

DnaJ (Hsp40) homolog, subfamily C, member 5 gamma:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for DNAJC5G Gene

ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4
SP1:
SP2:

Relevant External Links for DNAJC5G Gene

GeneLoc Exon Structure for
DNAJC5G
ECgene alternative splicing isoforms for
DNAJC5G

Expression for DNAJC5G Gene

mRNA expression in normal human tissues for DNAJC5G Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for DNAJC5G Gene

This gene is overexpressed in Testis (x26.2) and Brain - Cortex (x4.9).

Protein differential expression in normal tissues from HIPED for DNAJC5G Gene

This gene is overexpressed in Adipocyte (46.2) and Blymphocyte (22.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for DNAJC5G Gene



Protein tissue co-expression partners for DNAJC5G Gene

NURSA nuclear receptor signaling pathways regulating expression of DNAJC5G Gene:

DNAJC5G

SOURCE GeneReport for Unigene cluster for DNAJC5G Gene:

Hs.116303

mRNA Expression by UniProt/SwissProt for DNAJC5G Gene:

Q8N7S2-DNJ5G_HUMAN
Tissue specificity: Testis specific.
genes like me logo Genes that share expression patterns with DNAJC5G: view

Primer Products

Orthologs for DNAJC5G Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for DNAJC5G Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia DNAJC5G 34
  • 80.81 (n)
  • 75.58 (a)
DNAJC5G 35
  • 75 (a)
OneToOne
dog
(Canis familiaris)
Mammalia DNAJC5G 34
  • 86.29 (n)
  • 79.75 (a)
DNAJC5G 35
  • 79 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Dnajc5g 34
  • 75.76 (n)
  • 67.27 (a)
Dnajc5g 16
Dnajc5g 35
  • 67 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia DNAJC5G 34
  • 98.06 (n)
  • 95.77 (a)
DNAJC5G 35
  • 96 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Dnajc5g 34
  • 76.71 (n)
  • 72.44 (a)
oppossum
(Monodelphis domestica)
Mammalia DNAJC5G 35
  • 56 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia DNAJC5G 35
  • 49 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia -- 35
  • 25 (a)
ManyToMany
zebrafish
(Danio rerio)
Actinopterygii dnajc5ga 35
  • 41 (a)
OneToMany
dnajc5gb 35
  • 39 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta Csp 35
  • 33 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea dnj-14 35
  • 32 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes SIS1 35
  • 13 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea CSA.8441 35
  • 37 (a)
OneToMany
Species where no ortholog for DNAJC5G was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for DNAJC5G Gene

ENSEMBL:
Gene Tree for DNAJC5G (if available)
TreeFam:
Gene Tree for DNAJC5G (if available)

Paralogs for DNAJC5G Gene

Paralogs for DNAJC5G Gene

(11) SIMAP similar genes for DNAJC5G Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with DNAJC5G: view

Variants for DNAJC5G Gene

Sequence variations from dbSNP and Humsavar for DNAJC5G Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
VAR_033882 -
rs13414011 - 27,277,792(+) GTATC(A/G)CCTGG intron-variant, reference, missense
rs4665961 -- 27,277,513(+) CACCT(C/T)GGCCT intron-variant
rs11126950 -- 27,279,577(+) taggc(A/G)tgagc intron-variant
rs11901826 -- 27,278,175(+) TTCTC(A/G)CCTAC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for DNAJC5G Gene

Variant ID Type Subtype PubMed ID
esv3326859 CNV insertion 20981092
nsv833614 CNV gain 17160897

Variation tolerance for DNAJC5G Gene

Residual Variation Intolerance Score: 74.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.50; 55.33% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for DNAJC5G Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
DNAJC5G

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for DNAJC5G Gene

Disorders for DNAJC5G Gene

Relevant External Links for DNAJC5G

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
DNAJC5G

No disorders were found for DNAJC5G Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for DNAJC5G Gene

Publications for DNAJC5G Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 65
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 65
  3. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 4 65
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 65

Products for DNAJC5G Gene

Sources for DNAJC5G Gene

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