Aliases for DNAJC5 Gene
External Ids for DNAJC5 Gene
Previous HGNC Symbols for DNAJC5 Gene
Previous GeneCards Identifiers for DNAJC5 Gene
This gene is a member of the J protein family. J proteins function in many cellular processes by regulating the ATPase activity of 70 kDa heat shock proteins. The encoded protein plays a role in membrane trafficking and protein folding, and has been shown to have anti-neurodegenerative properties. The encoded protein is known to play a role in cystic fibrosis and Huntington's disease. A pseudogene of this gene is located on the short arm of chromosome 8. [provided by RefSeq, Nov 2010]
GeneCards Summary for DNAJC5 Gene
DNAJC5 (DnaJ (Hsp40) Homolog, Subfamily C, Member 5) is a Protein Coding gene. Diseases associated with DNAJC5 include ceroid lipofuscinosis, neuronal, 4, parry type and cln4 disease. Among its related pathways are Translational Control and Development Slit-Robo signaling. GO annotations related to this gene include glycoprotein binding and ATP-dependent protein binding. An important paralog of this gene is DNAJB7.
UniProtKB/Swiss-Prot for DNAJC5 Gene
May have an important role in presynaptic function. May be involved in calcium-dependent neurotransmitter release at nerve endings (By similarity).