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DNAJC25 Gene(Protein Coding)

DnaJ Heat Shock Protein Family (Hsp40) Member C25

GCID:
GC09P111632
GIFtS:
37
Genes Participants
UDN Logo

Aliases for DNAJC25 Gene

Aliases for DNAJC25 Gene

  • DnaJ Heat Shock Protein Family (Hsp40) Member C25 2 3 5
  • DnaJ (Hsp40) Homolog, Subfamily C , Member 25 2 3
  • DnaJ-Like Protein 3
  • BA16L21.2.1 3

External Ids for DNAJC25 Gene

Previous GeneCards Identifiers for DNAJC25 Gene

  • GC09P113444
  • GC09P113446
  • GC09P114393
  • GC09P083992

Summaries for DNAJC25 Gene

GeneCards Summary for DNAJC25 Gene

DNAJC25 (DnaJ Heat Shock Protein Family (Hsp40) Member C25) is a Protein Coding gene. An important paralog of this gene is DNAJC25-GNG10.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for DNAJC25 Gene

Genomics for DNAJC25 Gene

Products:

  1. Regulatory Element

Regulatory Elements for DNAJC25 Gene

Enhancers for DNAJC25 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around DNAJC25 on UCSC Golden Path with GeneCards custom track

Promoters for DNAJC25 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around DNAJC25 on UCSC Golden Path with GeneCards custom track

Transcription factor binding sites by QIAGEN in the DNAJC25 gene promoter:

Genomic Location for DNAJC25 Gene

Chromosome:
9
Start:
111,631,352 bp from pter
End:
111,654,351 bp from pter
Size:
23,000 bases
Orientation:
Plus strand

Genomic View for DNAJC25 Gene

Genes around DNAJC25 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
DNAJC25 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for DNAJC25 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for DNAJC25 Gene

Proteins for DNAJC25 Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

  • Protein details for DNAJC25 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9H1X3-DJC25_HUMAN
    Recommended name:
    DnaJ homolog subfamily C member 25
    Protein Accession:
    Q9H1X3
    Secondary Accessions:
    • Q5QTD8
    • Q96BN9

    Protein attributes for DNAJC25 Gene

    Size:
    360 amino acids
    Molecular mass:
    42404 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for DNAJC25 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for DNAJC25 Gene

Proteomics data for DNAJC25 Gene at MOPED

Protein Expression for DNAJC25 Gene

See protein expression from ProteomicsDB, MOPED, PaxDb, and MaxQB

Post-translational modifications for DNAJC25 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for DNAJC25 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for DNAJC25 Gene

Domains & Families for DNAJC25 Gene

Gene Families for DNAJC25 Gene

HGNC:

Protein Domains for DNAJC25 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for DNAJC25 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9H1X3

UniProtKB/Swiss-Prot:

DJC25_HUMAN :
  • Contains 1 J domain.
  • Belongs to the DNAJC25 family.
Domain:
  • Contains 1 J domain.
Family:
  • Belongs to the DNAJC25 family.
genes like me logo Genes that share domains with DNAJC25: view

Function for DNAJC25 Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line
  7. Flow Cytometry

Phenotypes for DNAJC25 Gene

GenomeRNAi human phenotypes for DNAJC25:
genes like me logo Genes that share phenotypes with DNAJC25: view

Animal Model Products

CRISPR Products

miRNA for DNAJC25 Gene

miRTarBase miRNAs that target DNAJC25

Inhibitory RNA Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for DNAJC25 Gene

Localization for DNAJC25 Gene

Subcellular locations from UniProtKB/Swiss-Prot for DNAJC25 Gene

Membrane; Multi-pass membrane protein.

No data available for Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for DNAJC25 Gene

Pathways & Interactions for DNAJC25 Gene

SuperPathways for DNAJC25 Gene

PathCards logoMore details on SuperPathways for DNAJC25
No Data Available

Gene Ontology (GO) - Biological Process for DNAJC25 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for DNAJC25 Gene

Drugs & Compounds for DNAJC25 Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for DNAJC25 Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone
  5. Flow Cytometry

mRNA/cDNA for DNAJC25 Gene

(1) REFSEQ mRNAs :
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for DNAJC25 Gene

ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9a · 9b ^ 10
SP1: -
SP2: - -
SP3:
SP4: - - -
SP5:
SP6:
SP7: - - - - - - - -

Relevant External Links for DNAJC25 Gene

GeneLoc Exon Structure for
DNAJC25
ECgene alternative splicing isoforms for
DNAJC25

Expression for DNAJC25 Gene

Products:

  1. Primer

mRNA expression in normal human tissues for DNAJC25 Gene

mRNA expression in normal human tissues for DNAJC25 Gene
mRNA expression by GTEx for DNAJC25 Gene

mRNA differential expression in normal tissues according to GTEx for DNAJC25 Gene

This gene is overexpressed in Liver (x4.2).

Protein differential expression in normal tissues from HIPED for DNAJC25 Gene

This gene is overexpressed in Adrenal (25.2), Bone (8.1), and Liver (7.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for DNAJC25 Gene



genes like me logo Genes that share expression patterns with DNAJC25: view

Protein tissue co-expression partners for DNAJC25 Gene

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for DNAJC25 Gene

Orthologs for DNAJC25 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for DNAJC25 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
 Mammalia DNAJC25 35
  • 89.79 (n)
  • 92.48 (a)
DNAJC25 36
  • 92 (a)
 OneToOne
dog
(Canis familiaris)
 Mammalia DNAJC25 35
  • 92.32 (n)
  • 96.88 (a)
DNAJC25 36
  • 94 (a)
 OneToOne
mouse
(Mus musculus)
 Mammalia Dnajc25 35
  • 87.86 (n)
  • 91.88 (a)
Dnajc25 16
Dnajc25 36
  • 92 (a)
 OneToOne
chimpanzee
(Pan troglodytes)
 Mammalia DNAJC25 35
  • 99.63 (n)
  • 99.72 (a)
DNAJC25 36
  • 100 (a)
 OneToOne
rat
(Rattus norvegicus)
 Mammalia Dnajc25 35
  • 86.4 (n)
  • 92.82 (a)
oppossum
(Monodelphis domestica)
 Mammalia -- 36
  • 77 (a)
 ManyToMany
-- 36
  • 55 (a)
 ManyToMany
platypus
(Ornithorhynchus anatinus)
 Mammalia DNAJC25 36
  • 77 (a)
 OneToMany
chicken
(Gallus gallus)
 Aves DNAJC25 35
  • 77.49 (n)
  • 80 (a)
-- 36
  • 78 (a)
 OneToMany
lizard
(Anolis carolinensis)
 Reptilia -- 36
  • 74 (a)
 OneToMany
tropical clawed frog
(Silurana tropicalis)
 Amphibia dnajc25 35
  • 70.36 (n)
  • 77.23 (a)
zebrafish
(Danio rerio)
 Actinopterygii dnajc25 35
  • 69.77 (n)
  • 72.98 (a)
dnajc25 36
  • 68 (a)
 OneToMany
African malaria mosquito
(Anopheles gambiae)
 Insecta AgaP_AGAP000831 35
  • 54.91 (n)
  • 48.72 (a)
fruit fly
(Drosophila melanogaster)
 Insecta CG7872 35
  • 59.39 (n)
  • 55.06 (a)
CG7872 36
  • 53 (a)
 OneToMany
worm
(Caenorhabditis elegans)
 Secernentea dnj-2 35
  • 50.38 (n)
  • 40.66 (a)
C47A4.1 36
  • 34 (a)
 ManyToMany
dnj-2 36
  • 39 (a)
 ManyToMany
thale cress
(Arabidopsis thaliana)
 eudicotyledons AT1G61770 35
  • 46.62 (n)
  • 33.58 (a)
rice
(Oryza sativa)
 Liliopsida Os12g0258200 35
  • 47.36 (n)
  • 34.32 (a)
sea squirt
(Ciona savignyi)
 Ascidiacea -- 36
  • 48 (a)
 OneToMany
Species with no ortholog for DNAJC25:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for DNAJC25 Gene

ENSEMBL:
Gene Tree for DNAJC25 (if available)
TreeFam:
Gene Tree for DNAJC25 (if available)

Paralogs for DNAJC25 Gene

Paralogs for DNAJC25 Gene

(3) SIMAP similar genes for DNAJC25 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with DNAJC25: view

Variants for DNAJC25 Gene

Structural Variations from Database of Genomic Variants (DGV) for DNAJC25 Gene

Variant ID Type Subtype PubMed ID
nsv893724 CNV Gain 21882294
nsv825041 CNV Gain 20364138
nsv893725 CNV Loss 21882294
nsv893726 CNV Gain 21882294

Variation tolerance for DNAJC25 Gene

Residual Variation Intolerance Score: 44.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.49; 71.76% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Relevant External Links for DNAJC25 Gene

Disorders for DNAJC25 Gene

Relevant External Links for DNAJC25

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
DNAJC25

No disorders were found for DNAJC25 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for DNAJC25 Gene

Publications for DNAJC25 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 67
  2. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein M.Y. … Mann M. (Cell 2015) 3
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for DNAJC25 Gene

Sources for DNAJC25 Gene

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