Aliases for DNAJC25 Gene
Aliases for DNAJC25 Gene
External Ids for DNAJC25 Gene
- HGNC: 34187
- Entrez Gene: 548645
- Ensembl: ENSG00000059769
- UniProtKB: Q9H1X3
Previous GeneCards Identifiers for DNAJC25 Gene
- GC09P113444
- GC09P113446
- GC09P114393
- GC09P083992
Summaries for DNAJC25 Gene
GeneCards Summary for DNAJC25 Gene
DNAJC25 (DnaJ Heat Shock Protein Family (Hsp40) Member C25) is a Protein Coding gene. An important paralog of this gene is DNAJC25-GNG10.
Additional gene information for DNAJC25 Gene
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for DNAJC25 Gene
Genomics for DNAJC25 Gene
GeneHancer (GH) Regulatory Elements for DNAJC25 Gene
Promoters and enhancers for DNAJC25 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around DNAJC25 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for DNAJC25 Gene
Genomic Locations for DNAJC25 Gene
- chr9:111,631,352-111,654,351
- (GRCh38/hg38)
- Size:
- 23,000 bases
- Orientation:
- Plus strand
- chr9:114,393,632-114,432,508
- (GRCh37/hg19)
Genomic View for DNAJC25 Gene
Genes around DNAJC25 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 9q31.3 by Ensembl
- 9q31.3 by Entrez Gene
- 9q31.3 by HGNC
DNAJC25 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for DNAJC25 Gene
Proteins for DNAJC25 Gene
-
Protein details for DNAJC25 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9H1X3-DJC25_HUMAN
- Recommended name:
- DnaJ homolog subfamily C member 25
- Protein Accession:
- Q9H1X3
- Q5QTD8
- Q96BN9
Protein attributes for DNAJC25 Gene
- Size:
- 360 amino acids
- Molecular mass:
- 42404 Da
- Quaternary structure:
- No Data Available
Protein Expression for DNAJC25 Gene
Post-translational modifications for DNAJC25 Gene
No Post-translational modifications
Other Protein References for DNAJC25 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for DNAJC25
- Novus Biologicals Antibodies for DNAJC25
- Invitrogen Antibodies for DNAJC25
- GeneTex DNAJC25 antibody for DNAJC25
Protein Products
-
OriGene Purified Proteins for DNAJC25
- Search Origene for MassSpec and Protein Over-expression Lysates for DNAJC25
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- Novus Biologicals proteins for DNAJC25
- Search GeneTex for Proteins for DNAJC25
Assay Products
No data available for DME Specific Peptides for DNAJC25 Gene
Domains & Families for DNAJC25 Gene
Gene Families for DNAJC25 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted membrane proteins
Protein Domains for DNAJC25 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for DNAJC25 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q9H1X3- Family:
-
- Belongs to the DNAJC25 family.
Function for DNAJC25 Gene
Phenotypes From GWAS Catalog for DNAJC25 Gene
Phenotypes for DNAJC25 Gene
- GenomeRNAi human phenotypes for DNAJC25:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
-
ViGene Biosciences lentiviral particle packaged cDNA for DNAJC25 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for DNAJC25 gene
- Search ViGene Biosciences for DNAJC25
CRISPR Products
-
OriGene CRISPR knockouts for DNAJC25
- genomics-online: gRNA clones - Search results for 89 available DNAJC25 gene related products
- Overview of 89 available DNAJC25 gene related products
- Applied Biological Materials CRISPR for DNAJC25
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for DNAJC25
- GenScript: Design CRISPR guide RNA sequences for DNAJC25
miRNA for DNAJC25 Gene
- miRTarBase miRNAs that target DNAJC25
miRNA Products
- Search ViGene Biosciences for DNAJC25
Inhibitory RNA Products
- Origene shrna, RNAi, and sirna products in human, mouse, rat for DNAJC25
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- Overview of 89 available DNAJC25 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for DNAJC25 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Applied Biological Materials Clones for DNAJC25
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for DNAJC25
-
ViGene Biosciences adenoviral particle packaged cDNA for DNAJC25 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for DNAJC25 gene
-
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No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for DNAJC25 Gene
Localization for DNAJC25 Gene
Subcellular locations from UniProtKB/Swiss-Prot for DNAJC25 Gene
- Membrane; Multi-pass membrane protein.
- Cytosol (2)
- Nucleoplasm (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005834 | heterotrimeric G-protein complex | IEA | -- |
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA | -- |
No data available for Subcellular locations from COMPARTMENTS for DNAJC25 Gene
Pathways & Interactions for DNAJC25 Gene
No Data Available
Interacting Proteins for DNAJC25 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007186 | G-protein coupled receptor signaling pathway | IEA | -- |
No data available for Pathways by source and SIGNOR curated interactions for DNAJC25 Gene
Transcripts for DNAJC25 Gene
mRNA/cDNA for DNAJC25 Gene
- (1) REFSEQ mRNAs :
- (3) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
-
OriGene CRISPR knockouts for DNAJC25
- genomics-online: gRNA clones - Search results for 89 available DNAJC25 gene related products
- Overview of 89 available DNAJC25 gene related products
- Applied Biological Materials CRISPR for DNAJC25
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for DNAJC25
- GenScript: Design CRISPR guide RNA sequences for DNAJC25
miRNA Products
- Search ViGene Biosciences for DNAJC25
Inhibitory RNA Products
- Origene shrna, RNAi, and sirna products in human, mouse, rat for DNAJC25
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- genomics-online: shRNA clones - Search results for 89 available DNAJC25 gene related products
- Overview of 89 available DNAJC25 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for DNAJC25 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Applied Biological Materials Clones for DNAJC25
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3a | · | 3b | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9a | · | 9b | ^ | 10 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | ||||||||||||||||||||||||
| SP2: | - | - | |||||||||||||||||||||||
| SP3: | |||||||||||||||||||||||||
| SP4: | - | - | - | ||||||||||||||||||||||
| SP5: | |||||||||||||||||||||||||
| SP6: | |||||||||||||||||||||||||
| SP7: | - | - | - | - | - | - | - | - |
Expression for DNAJC25 Gene
mRNA differential expression in normal tissues according to GTEx for DNAJC25 Gene
This gene is overexpressed in Liver (x4.2).
This gene is overexpressed in Adrenal (25.2), Bone (8.1), and Liver (7.6).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for DNAJC25 Gene
NURSA nuclear receptor signaling pathways regulating expression of DNAJC25 Gene:
DNAJC25Evidence on tissue expression from TISSUES for DNAJC25 Gene
- Liver(4.3)
- Kidney(4.2)
Primer Products
-
OriGene qPCR primer pairs and template standards for DNAJC25
-
OriGene qPCR primer pairs for DNAJC25
- genomics-online: primer clones - Search results for 89 available DNAJC25 gene related products
- Overview of 89 available DNAJC25 gene related products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for DNAJC25 Gene
Orthologs for DNAJC25 Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | DNAJC25 33 34 |
|
||
| dog (Canis familiaris) |
Mammalia | DNAJC25 33 34 |
|
||
| cow (Bos Taurus) |
Mammalia | DNAJC25 33 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Dnajc25 33 16 34 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Dnajc25 33 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | -- 34 |
|
ManyToMany | |
| -- 34 |
|
ManyToMany | |||
| platypus (Ornithorhynchus anatinus) |
Mammalia | DNAJC25 34 |
|
OneToMany | |
| chicken (Gallus gallus) |
Aves | -- 34 |
|
OneToMany | |
| DNAJC25 33 |
|
||||
| lizard (Anolis carolinensis) |
Reptilia | -- 34 |
|
OneToMany | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | dnajc25 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | dnajc25 33 34 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | CG7872 33 34 |
|
||
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP000831 33 |
|
||
| worm (Caenorhabditis elegans) |
Secernentea | dnj-2 33 34 |
|
||
| C47A4.1 34 |
|
ManyToMany | |||
| thale cress (Arabidopsis thaliana) |
eudicotyledons | AT1G61770 33 |
|
||
| rice (Oryza sativa) |
Liliopsida | Os12g0258200 33 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 34 |
|
OneToMany |
- Species where no ortholog for DNAJC25 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for DNAJC25 Gene
Paralogs for DNAJC25 Gene
(3) SIMAP similar genes for DNAJC25 Gene using alignment to 3 proteins:
Variants for DNAJC25 Gene
| SNP ID | Clin | Chr 09 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000459009 | -- | 111,634,178(+) | G/A | intron_variant | |
| rs1000810321 | -- | 111,634,482(+) | G/A | intron_variant | |
| rs1000841848 | -- | 111,654,599(+) | G/A/T | downstream_transcript_variant | |
| rs1000843696 | -- | 111,653,449(+) | T/G | 3_prime_UTR_variant, non_coding_transcript_variant | |
| rs1000915842 | -- | 111,647,010(+) | T/C | intron_variant |
Residual Variation Intolerance Score:
44.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
5.49;
71.76% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for DNAJC25 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- DNAJC25
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for DNAJC25 Gene
Disorders for DNAJC25 Gene
Additional Disease Information for DNAJC25
No disorders were found for DNAJC25 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for DNAJC25 Gene
Publications for DNAJC25 Gene
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
- A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein MY … Mann M (Cell 2015) 3 58
- An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. (PMID: 24275569) Bian Y … Zou H (Journal of proteomics 2014) 4 58
- DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray SJ … Dunham I (Nature 2004) 4 58
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4 58
Products for DNAJC25 Gene
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- Custom Antibody ServicesOriGene Antibodies for DNAJC25
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for DNAJC25
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- OriGene qPCR primer pairs and template standards for DNAJC25
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- Novus Biologicals Antibodies for DNAJC25
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- Browse Antibodies at Cloud-Clone Corp.
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- Cloud-Clone Corp. disease models service
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- Invitrogen Antibodies for DNAJC25
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
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- ViGene Biosciences adenoviral particle packaged cDNA for DNAJC25 gene
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- Overview of 89 available DNAJC25 gene related products
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- Overview of 89 available DNAJC25 gene related products
- genomics-online: gRNA clones - Search results for 89 available DNAJC25 gene related products
- Overview of 89 available DNAJC25 gene related products
- genomics-online: primer clones - Search results for 89 available DNAJC25 gene related products
- Overview of 89 available DNAJC25 gene related products
- genomics-online: shRNA clones - Search results for 89 available DNAJC25 gene related products
- Overview of 89 available DNAJC25 gene related products
Sources for DNAJC25 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew