DNAJC25 Gene
protein-coding GIFtS: 38
GCID: GC09P114393
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DnaJ (Hsp40) homolog, subfamily C , member 25
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Aliases
for DNAJC25 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA
Quality score for the ORGUL clustered with this gene is 3
| Aliases |
|---|
| DnaJ (Hsp40) Homolog, Subfamily C , Member 251 2 | | BA16L21.2.11 | | DnaJ Homolog Subfamily C Member 252 | | DnaJ-Like Protein2 |
| External Ids: | HGNC: 341871 | Entrez Gene: 5486452 | Ensembl: ENSG000000597697 | UniProtKB: Q9H1X33 | | ORGUL members: | |
|---|
| NONCODE:n410201 | |
Export aliases for DNAJC25 gene to outside databasesPrevious GC identifers: GC09P113444 GC09P113446 GC09P083992
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Summaries
for DNAJC25 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for DNAJC25 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the DNAJC25 gene promoter:
ER-alpha HFH-3 Sox5 p300 C/EBPalpha FOXI1 CREB CHOP-10 deltaCREB HSF2
Other transcription factors
Search SABiosciences Chromatin IP Primers for DNAJC25
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DNAJC25 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 9q31.3 Ensembl cytogenetic band: 9q31.3 HGNC cytogenetic band: 9q31.3DNAJC25 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 9 GeneLoc Exon Structure GeneLoc location for GC09P114393: view genomic region
(about GC identifiers)
Start:
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114,393,632 bp from pter |
End:
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114,432,508 bp from pter |
Size:
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38,877 bases |
Orientation:
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plus strand |
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Proteins
for DNAJC25 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: DJC25_HUMAN, Q9H1X3 (See
protein sequence)Recommended Name: DnaJ homolog subfamily C member 25 Size: 360 amino acids; 42404 Da
Subcellular location: Membrane; Multi-pass membrane protein (Potential)
Secondary accessions: Q5QTD8 Q96BN9Alternative splicing: 3 isoforms: Q9H1X3-1 Q9H1X3-2 Q9H1X3-3 Explore the universe of human proteins at neXtProt for DNAJC25: NX_Q9H1X3
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9H1X3
DNAJC25 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001015882.2
ENSEMBL proteins: ENSP00000320650 ENSP00000464086 ENSP00000399325 ENSP00000451984
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0016021 | integral to membrane |
IEA | -- |
DNAJC25 for ontologies About GeneDecksing
DNAJC25 Antibody Products:
Assay Products for DNAJC25: |
Protein
Domains /
Families
for DNAJC25 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
DNAJC25 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q9H1X3ProtoNet protein and cluster: Q9H1X3 UniProtKB/Swiss-Prot: DJC25_HUMAN, Q9H1X3Similarity: Belongs to the DNAJC25 familySimilarity: Contains 1 J domain |
Function
for DNAJC25 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DNAJC25 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DNAJC25 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: DNAJC25 (NM_001015882) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for DNAJC25 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DNAJC25 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DNAJC25 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0031072 | heat shock protein binding |
IEA | -- | | GO:0051082 | unfolded protein binding |
IEA | -- |
DNAJC25 for ontologies About GeneDecksing
|
Pathways & Interactions
for DNAJC25 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for DNAJC25
STRING Interaction
Network Preview (showing 2 interactants - click image to see more details)
3 Interacting proteins for DNAJC25 (Q9H1X33 ENSP000003206504) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006457 | protein folding |
IEA | -- |
DNAJC25 for ontologies About GeneDecksing
|
Drugs & Compounds
for DNAJC25 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for DNAJC25
Search CenterWatch for drugs/clinical trials and news about DNAJC25 / DJC25
|
Transcripts
for DNAJC25 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for DNAJC25 gene: NM_001015882.2 4 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000313525(uc004bfl.3) ENST00000463589 ENST00000447096(uc004bfm.3)
ENST00000556107
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DNAJC25 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DNAJC25 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: DNAJC25 (NM_001015882) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for DNAJC25 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DNAJC25 |
GeneLoc Exon Structure
5/7 Alternative Splicing Database (ASD) splice patterns (SP) for DNAJC25 (see all 7) About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3a | · | 3b | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9a | · | 9b | ^ | 10 |
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| SP1: | | | | | | | - | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | - | | - | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | - | | - | | - | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for DNAJC25
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Expression
for DNAJC25 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| DNAJC25 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See DNAJC25 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for DNAJC25
SABiosciences Custom PCR Arrays for DNAJC25
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DNAJC25
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat DNAJC25 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DNAJC25 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DNAJC25 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DNAJC25 |
Orthologs
for DNAJC25 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for DNAJC25 gene from 7/22 species (see all 22) About this table
ENSEMBL Gene Tree for DNAJC25 (if available)
TreeFam Gene Tree for DNAJC25 (if available) |
Paralogs
for DNAJC25 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for DNAJC25 gene
- DNAJC25-GNG102
3 SIMAP similar genes for DNAJC25 using alignment to 3 protein entries: DJC25_HUMAN (see all proteins):DNAJA2 DNAJA4 DNAJB6
DNAJC25 for paralogs About GeneDecksing
|
Genomic Variants
for DNAJC25 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 9 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for DNAJC25 (114393632 - 114432508 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for DNAJC25: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DNAJC25 |
|
Disorders
/ Diseases
for DNAJC25 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
DNAJC25 for disorders About GeneDecksing
1  disease for DNAJC25: About MalaCardsmalaria
Export disorders for DNAJC25 gene to outside databases
|
Publications
for DNAJC25 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for DNAJC25 gene integrated from 9 sources:
(articles sorted by number of sources associating them with DNAJC25) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)2 Humphray S.J.... Dunham I. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )2 Aoki H.... Hino O. (2000)
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External Searches for DNAJC25 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing DNAJC25 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing DNAJC25 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing DNAJC25 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for DNAJC25 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for DNAJC25 gene:
Search GeneIP for patents involving DNAJC25
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for DNAJC25 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for DNAJC25 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DNAJC25 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DNAJC25 | | | OriGene Protein Over-expression Lysate for DNAJC25 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for DNAJC25 | | OriGene 3'-UTR Clone for DNAJC25 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DNAJC25 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DNAJC25 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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 |  |  |  | |
| | | | Search Tocris compounds for DNAJC25 |
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 | | | DNAJC25 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DNAJC25 |
|  |  |  | | | | Search ThermoFisher Antibodies for DNAJC25 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DNAJC25 |
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