Aliases for DNAJC25 Gene
Aliases for DNAJC25 Gene
External Ids for DNAJC25 Gene
- HGNC: 34187
- Entrez Gene: 548645
- Ensembl: ENSG00000059769
- UniProtKB: Q9H1X3
Previous GeneCards Identifiers for DNAJC25 Gene
- GC09P113444
- GC09P113446
- GC09P114393
- GC09P083992
Summaries for DNAJC25 Gene
GeneCards Summary for DNAJC25 Gene
DNAJC25 (DnaJ Heat Shock Protein Family (Hsp40) Member C25) is a Protein Coding gene. An important paralog of this gene is DNAJC25-GNG10.
No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for DNAJC25 Gene
Genomics for DNAJC25 Gene
Regulatory Elements for DNAJC25 Gene
Enhancers for DNAJC25 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH09F111630 | 1.2 | ENCODE | 9.9 | +0.3 | 259 | 2.5 | HDGF PKNOX1 ARNT CREB3L1 MLX WRNIP1 ZFP64 ARID4B SIN3A FEZF1 | LRRC37A5P DNAJC25 DNAJC25-GNG10 GNG10 |
| GH09F112027 | 1.6 | FANTOM5 Ensembl ENCODE | 5.7 | +404.9 | 404912 | 16.8 | HDGF PKNOX1 WRNIP1 NSD2 SIN3A YBX1 GATA2 ZNF207 FOS DEK | RNU6-710P RNU6-1013P ENSG00000259953 DNAJC25 ENSG00000227531 LOC105376220 |
| GH09F111626 | 1.1 | FANTOM5 ENCODE | 6 | -3.9 | -3856 | 1.8 | HDGF ESRRA TFAP4 PKNOX1 ZNF384 CEBPG RAD21 POLR2A ZNF143 HNF4G | PTGR1 DNAJC25 LRRC37A5P PIR58841 |
| GH09F110990 | 0.8 | FANTOM5 ENCODE | 6.1 | -640.4 | -640425 | 1.2 | SCRT2 ZNF623 ATF2 | LPAR1 DNAJC25 ENSG00000207401 |
| GH09F111942 | 1 | Ensembl ENCODE | 4.8 | +313.1 | 313102 | 3.9 | PKNOX1 MTA2 CBFB CEBPB BMI1 TBX21 EP300 RELA EED IKZF1 | UGCG RNU6-710P RNU6-1013P GNG10 DNAJC25 MIR4668 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around DNAJC25 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the DNAJC25 gene promoter:
Regulatory Element Products
Genomic Location for DNAJC25 Gene
- Chromosome:
- 9
- Start:
- 111,631,352 bp from pter
- End:
- 111,654,351 bp from pter
- Size:
- 23,000 bases
- Orientation:
- Plus strand
Genomic View for DNAJC25 Gene
Genes around DNAJC25 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 9q31.3 by Ensembl
- 9q31.3 by Entrez Gene
- 9q31.3 by HGNC
DNAJC25 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for DNAJC25 Gene
Proteins for DNAJC25 Gene
-
Protein details for DNAJC25 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9H1X3-DJC25_HUMAN
- Recommended name:
- DnaJ homolog subfamily C member 25
- Protein Accession:
- Q9H1X3
- Q5QTD8
- Q96BN9
Protein attributes for DNAJC25 Gene
- Size:
- 360 amino acids
- Molecular mass:
- 42404 Da
- Quaternary structure:
- No Data Available
Protein Expression for DNAJC25 Gene
Post-translational modifications for DNAJC25 Gene
Other Protein References for DNAJC25 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for DNAJC25
- Novus Biologicals Antibodies for DNAJC25
-
Abcam antibodies for DNAJC25
- Invitrogen Antibodies for DNAJC25
- GeneTex DNAJC25 antibody for DNAJC25
Protein Products
-
OriGene Purified Proteins for DNAJC25
- Search Origene for MassSpec and Protein Over-expression Lysates for DNAJC25
- Origene Custom Protein Services for DNAJC25
- Novus Biologicals proteins for DNAJC25
- Search GeneTex for Proteins for DNAJC25
Assay Products
No data available for DME Specific Peptides for DNAJC25 Gene
Domains & Families for DNAJC25 Gene
Gene Families for DNAJC25 Gene
Protein Domains for DNAJC25 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for DNAJC25 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q9H1X3- Domain:
-
- Contains 1 J domain.
- Family:
-
- Belongs to the DNAJC25 family.
Function for DNAJC25 Gene
Phenotypes for DNAJC25 Gene
- GenomeRNAi human phenotypes for DNAJC25:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for DNAJC25
-
-
ViGene Biosciences lentiviral particle packaged cDNA for DNAJC25 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for DNAJC25 gene
- Search ViGene Biosciences for DNAJC25
CRISPR Products
-
OriGene CRISPR knockouts for DNAJC25
- GenScript: Design CRISPR guide RNA sequences for DNAJC25
miRNA for DNAJC25 Gene
- miRTarBase miRNAs that target DNAJC25
miRNA Products
- Search ViGene Biosciences for DNAJC25
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for DNAJC25
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for DNAJC25
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for DNAJC25
-
ViGene Biosciences adenoviral particle packaged cDNA for DNAJC25 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for DNAJC25 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for DNAJC25 gene
Flow Cytometry Products
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for DNAJC25 Gene
Localization for DNAJC25 Gene
Subcellular locations from UniProtKB/Swiss-Prot for DNAJC25 Gene
- Membrane; Multi-pass membrane protein.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0016021 | integral component of membrane | IEA | -- |
No data available for Subcellular locations from COMPARTMENTS for DNAJC25 Gene
Pathways & Interactions for DNAJC25 Gene
No Data Available
Interacting Proteins for DNAJC25 Gene
No data available for Pathways by source and SIGNOR curated interactions for DNAJC25 Gene
Transcripts for DNAJC25 Gene
mRNA/cDNA for DNAJC25 Gene
- (1) REFSEQ mRNAs :
- (3) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
-
OriGene CRISPR knockouts for DNAJC25
- GenScript: Design CRISPR guide RNA sequences for DNAJC25
miRNA Products
- Search ViGene Biosciences for DNAJC25
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for DNAJC25
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for DNAJC25
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3a | · | 3b | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9a | · | 9b | ^ | 10 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | ||||||||||||||||||||||||
| SP2: | - | - | |||||||||||||||||||||||
| SP3: | |||||||||||||||||||||||||
| SP4: | - | - | - | ||||||||||||||||||||||
| SP5: | |||||||||||||||||||||||||
| SP6: | |||||||||||||||||||||||||
| SP7: | - | - | - | - | - | - | - | - |
Expression for DNAJC25 Gene
mRNA differential expression in normal tissues according to GTEx for DNAJC25 Gene
This gene is overexpressed in Liver (x4.2).
This gene is overexpressed in Adrenal (25.2), Bone (8.1), and Liver (7.6).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for DNAJC25 Gene
NURSA nuclear receptor signaling pathways regulating expression of DNAJC25 Gene:
DNAJC25Primer Products
-
OriGene qPCR primer pairs and template standards for DNAJC25
-
OriGene qPCR primer pairs for DNAJC25
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for DNAJC25 Gene
Orthologs for DNAJC25 Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | DNAJC25 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | DNAJC25 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | DNAJC25 34 35 |
|
||
| mouse (Mus musculus) |
Mammalia | Dnajc25 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Dnajc25 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | -- 35 |
|
ManyToMany | |
| -- 35 |
|
ManyToMany | |||
| platypus (Ornithorhynchus anatinus) |
Mammalia | DNAJC25 35 |
|
OneToMany | |
| chicken (Gallus gallus) |
Aves | -- 35 |
|
OneToMany | |
| DNAJC25 34 |
|
||||
| lizard (Anolis carolinensis) |
Reptilia | -- 35 |
|
OneToMany | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | dnajc25 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | dnajc25 34 35 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | CG7872 34 35 |
|
||
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP000831 34 |
|
||
| worm (Caenorhabditis elegans) |
Secernentea | dnj-2 34 35 |
|
||
| C47A4.1 35 |
|
ManyToMany | |||
| thale cress (Arabidopsis thaliana) |
eudicotyledons | AT1G61770 34 |
|
||
| rice (Oryza sativa) |
Liliopsida | Os12g0258200 34 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 35 |
|
OneToMany |
- Species where no ortholog for DNAJC25 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for DNAJC25 Gene
Paralogs for DNAJC25 Gene
(3) SIMAP similar genes for DNAJC25 Gene using alignment to 3 proteins:
Variants for DNAJC25 Gene
| SNP ID | Clin | Chr 09 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs10121084 | -- | 111,630,126(+) | TATAT(A/G)TGTAA | intron-variant, upstream-variant-2KB | |
| rs1013923 | -- | 111,650,293(+) | CCACA(C/G)AGACT | intron-variant | |
| rs1013925 | -- | 111,651,054(+) | TTGAG(A/G)TCAGG | intron-variant | |
| rs10435862 | -- | 111,645,319(+) | GTACA(A/G)TCTCG | intron-variant | |
| rs1051423 | -- | 111,654,018(+) | CTCTC(G/T)TCACT | intron-variant, nc-transcript-variant, utr-variant-3-prime |
Residual Variation Intolerance Score:
44.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
5.49;
71.76% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for DNAJC25 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- DNAJC25
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for DNAJC25 Gene
Disorders for DNAJC25 Gene
Relevant External Links for DNAJC25
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- DNAJC25
No disorders were found for DNAJC25 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for DNAJC25 Gene
Publications for DNAJC25 Gene
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
- A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein M.Y. … Mann M. (Cell 2015) 3 64
- An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. (PMID: 24275569) Bian Y. … Zou H. (J. Proteomics 2014) 4 64
- DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray S.J. … Dunham I. (Nature 2004) 4 64
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64
Products for DNAJC25 Gene
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- Custom Antibody ServicesOriGene Antibodies for DNAJC25
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for DNAJC25
- Search Origene for MassSpec and Protein Over-expression Lysates for DNAJC25
- Origene Custom Protein Services for DNAJC25
- Origene mouse_rna, siRNA, rat_shrna, shRNA, and RNAi products in human, mouse, rat for DNAJC25
- Browse OriGene Inhibitory RNA Products For DNAJC25
- OriGene qPCR primer pairs and template standards for DNAJC25
- OriGene qPCR primer pairs for DNAJC25
- OriGene CRISPR knockouts for DNAJC25
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- GenScript: Design CRISPR guide RNA sequences for DNAJC25
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- Novus Biologicals Antibodies for DNAJC25
- Novus Biologicals proteins for DNAJC25
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- ViGene Biosciences adenoviral particle packaged cDNA for DNAJC25 gene
- ViGene Biosciences lentiviral particle packaged cDNA for DNAJC25 gene
- ViGene Biosciences ready-to-package AAV shRNAs for DNAJC25 gene
- Search ViGene Biosciences for DNAJC25
- Horizon Cell Lines for DNAJC25
- Cyagen custom Knockout/knockin (KOKI) mouse models for DNAJC25
- VectorBuilder custom plasmid, inducible vectors for DNAJC25
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for DNAJC25
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for DNAJC25 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab