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DNAJC24 Gene

protein-coding   GIFtS: 46
GCID: GC11P031349

DnaJ (Hsp40) Homolog, Subfamily C, Member 24

(Previous names: zinc finger, CSL-type containing 3, DPH4 homolog (JJJ3,...)
(Previous symbols: ZCSL3, DPH4)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
DnaJ (Hsp40) Homolog, Subfamily C, Member 241 2     DPH4, JJJ3 Homolog (S. Cerevisiae)1
DPH41 2 3 5     1700030A21Rik2
ZCSL31 2 3     JJJ32
DPH4 Homolog (JJJ3, S. Cerevisiae)1 2     DnaJ Homolog Subfamily C Member 242
Zinc Finger, CSL-Type Containing 31 2     DPH4, JJJ3 Homolog2
Diphthamide Biosynthesis Protein 42 3     Zinc Finger, CSL Domain Containing 32
CSL-Type Zinc Finger-Containing Protein 32 3     

External Ids:    HGNC: 269791   Entrez Gene: 1205262   Ensembl: ENSG000001709467   OMIM: 6110725   UniProtKB: Q6P3W23   
ORGUL members:         

Export aliases for DNAJC24 gene to outside databases

Previous GC identifer: GC11P031085


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for DNAJC24 Gene:
Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2
(EEF2; MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for
ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH4 is 1 of
several enzymes involved in synthesis of diphthamide in EEF2 (Liu et al., 2004 (PubMed 15485916)).(supplied by
OMIM, Mar 2008)

GeneCards Summary for DNAJC24 Gene:
DNAJC24 (DnaJ (Hsp40) homolog, subfamily C, member 24) is a protein-coding gene. GO annotations related to this gene include ATPase activator activity and ferrous iron binding.

UniProtKB/Swiss-Prot: DJC24_HUMAN, Q6P3W2
Function: Stimulates the ATPase activity of several Hsp70-type chaperones. This ability is enhanced by
iron-binding. The iron-bound form is redox-active and can function as electron carrier. Plays a role in the
diphthamide biosynthesis, a post-translational modification of histidine which occurs in translation elongation
factor 2 (EEF2) which can be ADP-ribosylated by diphtheria toxin and by Pseudomonas exotoxin A (Eta)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000011.9  NC_018922.2  NT_009237.19  
Regulatory elements:
   Regulatory transcription factor binding sites in the DNAJC24 gene promoter:
         HFH-3   AML1a   POU3F2 (N-Oct-5a)   POU3F2 (N-Oct-5b)   HNF-3beta   POU3F2   FOXI1   POU2F1   POU2F1a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidDNAJC24 promoter sequence
   Search Chromatin IP Primers for DNAJC24

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat DNAJC24


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11p13   Ensembl cytogenetic band:  11p13   HGNC cytogenetic band: 11p14.1

DNAJC24 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DNAJC24 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11P031349:  view genomic region     (about GC identifiers)

Start:
31,391,377 bp from pter      End:
31,454,382 bp from pter
Size:
63,006 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: DJC24_HUMAN, Q6P3W2 (See protein sequence)
Recommended Name: DnaJ homolog subfamily C member 24  
Size: 148 amino acids; 17008 Da
Subunit: Monomer and homooligomer. Iron binding promotes oligomerization
Sequence caution: Sequence=EAW68245.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
1 PDB 3D structure from and Proteopedia for DNAJC24:
2L6L (3D)    
Secondary accessions: A8K0V0 B1ALC1

Explore the universe of human proteins at neXtProt for DNAJC24: NX_Q6P3W2

Explore proteomics data for DNAJC24 at MOPED


See DNAJC24 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_859057.4  
ENSEMBL proteins: 
 ENSP00000417548   ENSP00000432072   ENSP00000435771   ENSP00000434114   ENSP00000432388  
 ENSP00000379279   ENSP00000444967  

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ProSpec Recombinant Protein for DNAJC24
Cloud-Clone Corp. Proteins for DNAJC24

 
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(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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HGNC Gene Families:
DNAJ: Heat shock proteins / DNAJ (HSP40)

2 InterPro protein domains:
 IPR001623 DnaJ_domain
 IPR007872 Znf_DHP

Graphical View of Domain Structure for InterPro Entry Q6P3W2

ProtoNet protein and cluster: Q6P3W2

UniProtKB/Swiss-Prot: DJC24_HUMAN, Q6P3W2
Domain: The DPH-type zinc finger can also bind iron ions instead of the expected zinc ions (PubMed:22367199)
Similarity: Belongs to the DPH4 family
Similarity: Contains 1 DPH-type zinc finger
Similarity: Contains 1 J domain


Find genes that share domains with DNAJC24           About GenesLikeMe


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

     UniProtKB/Swiss-Prot Summary: DJC24_HUMAN, Q6P3W2
Function: Stimulates the ATPase activity of several Hsp70-type chaperones. This ability is enhanced by
iron-binding. The iron-bound form is redox-active and can function as electron carrier. Plays a role in the
diphthamide biosynthesis, a post-translational modification of histidine which occurs in translation elongation
factor 2 (EEF2) which can be ADP-ribosylated by diphtheria toxin and by Pseudomonas exotoxin A (Eta)

     Gene Ontology (GO): 3 molecular function terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0001671ATPase activator activity IDA--
GO:0008198ferrous iron binding IDA--
GO:0008270zinc ion binding IDA--
     
Find genes that share ontologies with DNAJC24           About GenesLikeMe


Phenotypes:
     4 MGI mutant phenotypes (inferred from 1 allele(MGI details for Dnajc24):
 embryogenesis  growth/size/body  limbs/digits/tail  mortality/aging 

Find genes that share phenotypes with DNAJC24           About GenesLikeMe

Animal Models:
   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for DNAJC24
   inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for DNAJC24

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for DNAJC24
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for DNAJC24

miRNA
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Selected qRT-PCR Assays for microRNAs that regulate DNAJC24 (see all 11):
hsa-miR-203 hsa-miR-148b* hsa-miR-34c-5p hsa-miR-4328 hsa-miR-449b hsa-miR-1261 hsa-miR-449a hsa-miR-3647-3p
SwitchGear 3'UTR luciferase reporter plasmidDNAJC24 3' UTR sequence
Inhib. RNA
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GenScript: all cDNA clones in your preferred vector: DNAJC24 (NM_181706)
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Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DNAJC24

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(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot
DJC24_HUMAN, Q6P3W2: Cytoplasm, cytoskeleton (By similarity)
Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
cytosol3
extracellular2
nucleus1
plasma membrane1

Gene Ontology (GO): 2 cellular component terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005737cytoplasm IEA--
GO:0005856cytoskeleton IEA--

Find genes that share ontologies with DNAJC24           About GenesLikeMe


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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UniProtKB/Swiss-Prot: DJC24_HUMAN, Q6P3W2
Pathway: Protein modification; peptidyl-diphthamide biosynthesis

    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for DNAJC24
Interactions:

    Search GeneGlobe Interaction Network for DNAJC24

STRING Interaction Network Preview (showing 5 interactants - click image to see 16)

Selected Interacting proteins for DNAJC24 (ENSP000003792794) via UniProtKB, MINT, STRING, and/or I2D (see all 16)

InteractantInteraction Details
GeneCardExternal ID(s)
HSPA9ENSP000002971854STRING: ENSP00000297185
NIPBLENSP000002825164STRING: ENSP00000282516
ANKRD45ENSP000003312684STRING: ENSP00000331268
HSPA5ENSP000003241734STRING: ENSP00000324173
SLC9C2ENSP000003566874STRING: ENSP00000356687
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Gene Ontology (GO): 4 biological process terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0017183peptidyl-diphthamide biosynthetic process from peptidyl-histidine IEA--
GO:0032781positive regulation of ATPase activity IDA--
GO:0055114oxidation-reduction process IEA--
GO:0061077chaperone-mediated protein folding TAS--

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for DNAJC24 (DJC24)



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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REFSEQ mRNAs for DNAJC24 gene: 
NM_181706.4  

Unigene Cluster for DNAJC24:

DnaJ (Hsp40) homolog, subfamily C, member 24
Hs.187269  [show with all ESTs]
Unigene Representative Sequence: NM_181706
12 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000527601 ENST00000529086(uc001msw.1) ENST00000465995(uc001msx.3 uc009yjm.3)
ENST00000532385 ENST00000525511 ENST00000526042 ENST00000526529 ENST00000527731
ENST00000530125 ENST00000524747 ENST00000395949 ENST00000536040
miRNA
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Selected qRT-PCR Assays for microRNAs that regulate DNAJC24 (see all 11):
hsa-miR-203 hsa-miR-148b* hsa-miR-34c-5p hsa-miR-4328 hsa-miR-449b hsa-miR-1261 hsa-miR-449a hsa-miR-3647-3p
SwitchGear 3'UTR luciferase reporter plasmidDNAJC24 3' UTR sequence
Inhib. RNA
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Predesigned siRNA for gene silencing in human, mouse, rat DNAJC24
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GenScript: all cDNA clones in your preferred vector: DNAJC24 (NM_181706)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for DNAJC24
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DNAJC24
Primer
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OriGene qSTAR qPCR primer pairs in human, mouse for DNAJC24
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat DNAJC24
  QuantiTect SYBR Green Assays in human, mouse, rat DNAJC24
  QuantiFast Probe-based Assays in human, mouse, rat DNAJC24

Additional mRNA sequence: 

AK123087.1 AK289665.1 AL833128.1 BC044931.2 

16 DOTS entries:

DT.412622  DT.101955555  DT.100680785  DT.75179417  DT.102827424  DT.92417760  DT.100016706  DT.99987630 
DT.95185356  DT.120706992  DT.438183  DT.75177772  DT.91672499  DT.92425233  DT.92425236  DT.95168892 

Selected AceView cDNA sequences (see all 65):

AK123087 BG109354 BQ932622 BF062368 BC044931 AI337249 BU952598 AI581597 
AL833128 BU951162 CK430132 BF984096 BU602510 AW772288 BU070821 BU784248 
CD357791 NM_181706 BF576796 BE883168 AW243323 AA834941 BG611909 BX283850 

GeneLoc Exon Structure

Selected Alternative Splicing Database (ASD) splice patterns (SP) for DNAJC24 (see all 6)    About this scheme

ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10a · 10b · 10c
SP1:                                      -     -     -           -     -           -                     
SP2:                                      -     -     -           -                                       
SP3:                                                                                                      
SP4:                                      -     -     -                                                   
SP5:                                      -     -     -     -     -     -           -                     


ECgene alternative splicing isoforms for DNAJC24

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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DNAJC24 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: --
DNAJC24 Expression
About this image

DNAJC24 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

DNAJC24 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.187269
    Custom PCR Arrays for DNAJC24
Primer
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In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DNAJC24

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of chordates.

Orthologs for DNAJC24 gene from Selected species (see all 12)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Dnajc241 , 5 DnaJ (Hsp40) homolog, subfamily C, member 241, 5 83.56(n)1
84.93(a)1
  2 (55.46 cM)5
993491  NM_026992.31  NP_081268.11 
 1059667095 
chicken
(Gallus gallus)
Aves DNAJC241 DnaJ (Hsp40) homolog, subfamily C, member 24 72.83(n)
66.44(a)
  421603  NM_001190896.1  NP_001177825.1 
lizard
(Anolis carolinensis)
Reptilia --
--
Uncharacterized protein
66(a)
58(a)
many → 1
many → 1
1(60350733-60371354)
2(65822139-65822993)
tropical clawed frog
(Xenopus tropicalis)
Amphibia dnajc241 DnaJ (Hsp40) homolog, subfamily C, member 24 60.23(n)
54.48(a)
  733569  NM_001044478.2  NP_001037943.2 
zebrafish
(Danio rerio)
Actinopterygii dnajc241 DnaJ (Hsp40) homolog, subfamily C, member 24 60.42(n)
50.69(a)
  393424  NM_200452.1  NP_956746.1 


ENSEMBL Gene Tree for DNAJC24 (if available)
TreeFam Gene Tree for DNAJC24 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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Paralogs for DNAJC24 gene
15 SIMAP similar genes for DNAJC24 using alignment to 6 protein entries:     DJC24_HUMAN (see all proteins):
ZCSL3    DPH3    DPH3P1    DNAJB4    DNAJB5    DNAJB12
DNAJC18    DNAJA4    DNAJB6    DNAJC10    DNAJB2    DNAJC4
DNAJC5G    DNAJA3    DNAJC5B

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1 Pseudogenes.org Pseudogene for DNAJC24
PGOHUM00000235398


(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for DNAJC24 (see all 904)    About this table                                 

Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 11 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
VAR_0363974
A breast cancer sample4--see VAR_0363972 N D mis40--------
rs618799231,2
C,F--31393424(+) AGGGTT/GCAATG 1 -- int11Minor allele frequency- G:0.00NA 2
rs5431381,2
C,F,A--31393465(+) tcccaC/Gtttca 1 -- int15Minor allele frequency- G:0.14WA NA CSA EA 128
rs1831783301,2
--31393590(+) GTCTCA/GAACAC 1 -- int10--------
rs6584771,2
C,F,A--31393617(+) ctcccG/Acctca 1 -- int13Minor allele frequency- A:0.33NA WA 6
rs6581061,2
C,F,A--31393662(+) actgcA/Ccccgg 1 -- int18Minor allele frequency- C:0.30NA WA CSA EA 368
rs1875090591,2
--31393740(+) TTTCAA/GTCTGT 1 -- int10--------
rs1932622171,2
--31393941(+) GTACTA/GATATT 1 -- int10--------
rs71089981,2
C,F,H--31394060(+) AATATT/AAAACC 1 -- int18Minor allele frequency- A:0.05NS EA NA WA 526
rs1388661131,2
--31394119(+) ACTGGA/TTCATT 1 -- int10--------

HapMap Linkage Disequilibrium report for DNAJC24 (31391377 - 31454382 bp)

Structural Variations
     Database of Genomic Variants (DGV) Selected variations for DNAJC24 (see all 18):    About this table    
Variant IDTypeSubtypePubMed ID
dgv197e199CNV Deletion23128226
esv2744311CNV Deletion23290073
esv2744312CNV Deletion23290073
nsv820987CNV Deletion20802225
nsv514608CNV Loss21397061
dgv205n67CNV Loss20364138
esv1006845CNV Loss20482838
nsv508621CNV Loss20534489
nsv498752CNV Loss21111241
nsv897178CNV Loss21882294

Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing DNAJC24
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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 611072    OMIM disorders: --

1 disease from the University of Copenhagen DISEASES database for DNAJC24:
Aniridia

Find genes that share disorders with DNAJC24           About GenesLikeMe


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(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for DNAJC24 gene integrated from 10 sources:
(articles sorted by number of sources associating them with DNAJC24)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Structure and mechanistic insights into novel iron-mediated moonlighting functions of human J-protein cochaperone, Dph4. (PubMed id 22367199)1, 2 Thakur A....D'Silva P. (J. Biol. Chem. 2012)
  2. Immunotoxin resistance via reversible methylation of the DPH4 promoter is a unique survival strategy. (PubMed id 22509046)1, 2 Wei H....Pastan I. (Proc. Natl. Acad. Sci. U.S.A. 2012)
  3. Identification of the proteins required for biosynthesis of diphthamide, the target of bacterial ADP-ribosylating toxins on translation elongation factor 2. (PubMed id 15485916)1, 3 Liu S....Leppla S.H. (Mol. Cell. Biol. 2004)
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
  6. The consensus coding sequences of human breast and colorectal cancers. (PubMed id 16959974)2 Sjoeblom T.... Velculescu V.E. (Science 2006)
  7. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PubMed id 16554811)2 Taylor T.D....Sakaki Y. (Nature 2006)
  8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 120526 HGNC: 26979 AceView: ZCSL3 Ensembl:ENSG00000170946 euGenes: HUgn120526
ECgene: DNAJC24 H-InvDB: DNAJC24

(According to HUGE)
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  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for DNAJC24 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for DNAJC24 gene:
Search GeneIP for patents involving DNAJC24

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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