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Aliases for DNAJC18 Gene

Aliases for DNAJC18 Gene

  • DnaJ (Hsp40) Homolog, Subfamily C, Member 18 2 3

External Ids for DNAJC18 Gene

Summaries for DNAJC18 Gene

GeneCards Summary for DNAJC18 Gene

DNAJC18 (DnaJ (Hsp40) Homolog, Subfamily C, Member 18) is a Protein Coding gene. Diseases associated with DNAJC18 include lung cancer. An important paralog of this gene is DNAJB14.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for DNAJC18 Gene

Genomics for DNAJC18 Gene

Genomic Location for DNAJC18 Gene

Start:
139,408,588 bp from pter
End:
139,444,491 bp from pter
Size:
35,904 bases
Orientation:
Minus strand

Genomic View for DNAJC18 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for DNAJC18 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for DNAJC18 Gene

Regulatory Elements for DNAJC18 Gene

Proteins for DNAJC18 Gene

  • Protein details for DNAJC18 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9H819-DJC18_HUMAN
    Recommended name:
    DnaJ homolog subfamily C member 18
    Protein Accession:
    Q9H819
    Secondary Accessions:

    Protein attributes for DNAJC18 Gene

    Size:
    358 amino acids
    Molecular mass:
    41551 Da
    Quaternary structure:
    No Data Available

neXtProt entry for DNAJC18 Gene

Proteomics data for DNAJC18 Gene at MOPED

Post-translational modifications for DNAJC18 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for DNAJC18 Gene

Domains for DNAJC18 Gene

Gene Families for DNAJC18 Gene

HGNC:
  • DNAJ :Heat shock proteins / DNAJ (HSP40)

Protein Domains for DNAJC18 Gene

UniProtKB/Swiss-Prot:

DJC18_HUMAN
Domain:
  • Contains 1 J domain.:
    • Q9H819
genes like me logo Genes that share domains with DNAJC18: view

Function for DNAJC18 Gene

miRNA for DNAJC18 Gene

miRTarBase miRNAs that target DNAJC18

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for DNAJC18 Gene

Localization for DNAJC18 Gene

Subcellular locations from UniProtKB/Swiss-Prot for DNAJC18 Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for DNAJC18 Gene COMPARTMENTS Subcellular localization image for DNAJC18 gene
Compartment Confidence
cytosol 3
golgi apparatus 1
mitochondrion 1
nucleus 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for DNAJC18 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with DNAJC18: view

Pathways for DNAJC18 Gene

SuperPathways for DNAJC18 Gene

No Data Available

Interacting Proteins for DNAJC18 Gene

Gene Ontology (GO) - Biological Process for DNAJC18 Gene

None

No data available for Pathways by source for DNAJC18 Gene

Transcripts for DNAJC18 Gene

mRNA/cDNA for DNAJC18 Gene

Unigene Clusters for DNAJC18 Gene

DnaJ (Hsp40) homolog, subfamily C, member 18:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for DNAJC18 Gene

ExUns: 1 ^ 2a · 2b · 2c ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b ^ 7 ^ 8 ^ 9
SP1:
SP2:
SP3: -
SP4: - -

Relevant External Links for DNAJC18 Gene

GeneLoc Exon Structure for
DNAJC18
ECgene alternative splicing isoforms for
DNAJC18

Expression for DNAJC18 Gene

mRNA expression in normal human tissues for DNAJC18 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for DNAJC18 Gene

SOURCE GeneReport for Unigene cluster for DNAJC18 Gene Hs.483537

genes like me logo Genes that share expressions with DNAJC18: view

Orthologs for DNAJC18 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for DNAJC18 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia DNAJC18 36
  • 99.35 (n)
  • 99.44 (a)
DNAJC18 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia DNAJC18 36
  • 93.48 (n)
  • 96.65 (a)
DNAJC18 37
  • 97 (a)
OneToOne
dog
(Canis familiaris)
Mammalia DNAJC18 36
  • 92.13 (n)
  • 94.1 (a)
DNAJC18 37
  • 94 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Dnajc18 36
  • 85.62 (n)
  • 87.11 (a)
Dnajc18 16
Dnajc18 37
  • 90 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia DNAJC18 37
  • 82 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia DNAJC18 37
  • 68 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Dnajc18 36
  • 84.28 (n)
  • 87.34 (a)
chicken
(Gallus gallus)
Aves DNAJC18 36
  • 71.77 (n)
  • 75.85 (a)
DNAJC18 37
  • 76 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia DNAJC18 37
  • 68 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii dnajc18 36
  • 61.97 (n)
  • 59.53 (a)
dnajc18 37
  • 49 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta CG30156 37
  • 22 (a)
ManyToMany
CG3061 37
  • 32 (a)
ManyToMany
worm
(Caenorhabditis elegans)
Secernentea dnj-1 37
  • 31 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes HLJ1 37
  • 22 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 37
  • 34 (a)
OneToMany
Species with no ortholog for DNAJC18:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for DNAJC18 Gene

ENSEMBL:
Gene Tree for DNAJC18 (if available)
TreeFam:
Gene Tree for DNAJC18 (if available)

Paralogs for DNAJC18 Gene

Paralogs for DNAJC18 Gene

genes like me logo Genes that share paralogs with DNAJC18: view

Variants for DNAJC18 Gene

Sequence variations from dbSNP and Humsavar for DNAJC18 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type MAF
rs11477 -- 139,411,771(+) TTACT(C/T)ATCGC utr-variant-3-prime
rs14764 -- 139,414,193(+) TCACA(A/G)TTTTC reference, synonymous-codon
rs1130301 -- 139,412,128(-) CAGGT(A/T)AAGAT utr-variant-3-prime
rs3923059 -- 139,439,484(+) CCCCG(C/T)GCCCG utr-variant-5-prime
rs3923060 -- 139,439,612(+) GGAGA(C/T)GCAGA upstream-variant-2KB, intron-variant

Structural Variations from Database of Genomic Variants (DGV) for DNAJC18 Gene

Variant ID Type Subtype PubMed ID
nsv519808 CNV Loss 19592680

Relevant External Links for DNAJC18 Gene

HapMap Linkage Disequilibrium report
DNAJC18

Disorders for DNAJC18 Gene

(1) MalaCards Diseases for DNAJC18 Gene

Search for DNAJC18 Gene in MalaCards »

Relevant External Links for DNAJC18

Genetic Association Database (GAD)
DNAJC18
Human Genome Epidemiology (HuGE) Navigator
DNAJC18
genes like me logo Genes that share disorders with DNAJC18: view

No data available for UniProtKB/Swiss-Prot for DNAJC18 Gene

Publications for DNAJC18 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway. (PMID: 18676680) Hosgood H.D. … Lan Q. (Carcinogenesis 2008) 3 49
  4. Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China. (PMID: 19170196) Shen M. … Lan Q. (Environ. Mol. Mutagen. 2009) 3 49
  5. Integrated genomic analysis implicates haploinsufficiency of multiple chromosome 5q31.2 genes in de novo myelodysplastic syndromes pathogenesis. (PMID: 19240791) Graubert T.A. … Walter M.J. (PLoS ONE 2009) 3 49

Products for DNAJC18 Gene

Sources for DNAJC18 Gene

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