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Aliases for DNAJC17 Gene

Aliases for DNAJC17 Gene

  • DnaJ (Hsp40) Homolog, Subfamily C, Member 17 2 3

External Ids for DNAJC17 Gene

Previous GeneCards Identifiers for DNAJC17 Gene

  • GC15M038848
  • GC15M041060
  • GC15M017908

Summaries for DNAJC17 Gene

GeneCards Summary for DNAJC17 Gene

DNAJC17 (DnaJ (Hsp40) Homolog, Subfamily C, Member 17) is a Protein Coding gene. GO annotations related to this gene include RNA binding and nucleotide binding. An important paralog of this gene is DNAJC12.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for DNAJC17 Gene

Genomics for DNAJC17 Gene

Regulatory Elements for DNAJC17 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for DNAJC17 Gene

Start:
40,765,155 bp from pter
End:
40,807,478 bp from pter
Size:
42,324 bases
Orientation:
Minus strand

Genomic View for DNAJC17 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for DNAJC17 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for DNAJC17 Gene

Proteins for DNAJC17 Gene

  • Protein details for DNAJC17 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9NVM6-DJC17_HUMAN
    Recommended name:
    DnaJ homolog subfamily C member 17
    Protein Accession:
    Q9NVM6
    Secondary Accessions:

    Protein attributes for DNAJC17 Gene

    Size:
    304 amino acids
    Molecular mass:
    34687 Da
    Quaternary structure:
    No Data Available

    Three dimensional structures from OCA and Proteopedia for DNAJC17 Gene

neXtProt entry for DNAJC17 Gene

Proteomics data for DNAJC17 Gene at MOPED

Post-translational modifications for DNAJC17 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for DNAJC17 Gene

Antibody Products

No data available for DME Specific Peptides for DNAJC17 Gene

Domains for DNAJC17 Gene

Gene Families for DNAJC17 Gene

HGNC:
  • DNAJ :Heat shock proteins / DNAJ (HSP40)
  • RBM :RNA binding motif (RRM) containing

Protein Domains for DNAJC17 Gene

Suggested Antigen Peptide Sequences for DNAJC17 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9NVM6

UniProtKB/Swiss-Prot:

DJC17_HUMAN :
  • Q9NVM6
Domain:
  • Contains 1 J domain.
  • Contains 1 RRM (RNA recognition motif) domain.
genes like me logo Genes that share domains with DNAJC17: view

Function for DNAJC17 Gene

Gene Ontology (GO) - Molecular Function for DNAJC17 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000166 nucleotide binding IEA --
GO:0003676 nucleic acid binding --
GO:0003723 RNA binding IEA --
genes like me logo Genes that share ontologies with DNAJC17: view

Phenotypes for DNAJC17 Gene

MGI mutant phenotypes for DNAJC17:
inferred from 1 alleles
GenomeRNAi human phenotypes for DNAJC17:
genes like me logo Genes that share phenotypes with DNAJC17: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for DNAJC17

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for DNAJC17 Gene

Localization for DNAJC17 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for DNAJC17 Gene COMPARTMENTS Subcellular localization image for DNAJC17 gene
Compartment Confidence
cytosol 2
nucleus 2

Gene Ontology (GO) - Cellular Components for DNAJC17 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
GO:0005737 cytoplasm IEA --
genes like me logo Genes that share ontologies with DNAJC17: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for DNAJC17 Gene

Pathways for DNAJC17 Gene

SuperPathways for DNAJC17 Gene

No Data Available

PCR Array Products

  • Pathway & Disease-focused RT² Profiler PCR Arrays

Interacting Proteins for DNAJC17 Gene

Gene Ontology (GO) - Biological Process for DNAJC17 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000122 negative regulation of transcription from RNA polymerase II promoter IEA --
GO:1901998 toxin transport IEA --
genes like me logo Genes that share ontologies with DNAJC17: view

No data available for Pathways by source for DNAJC17 Gene

Transcripts for DNAJC17 Gene

Unigene Clusters for DNAJC17 Gene

DnaJ (Hsp40) homolog, subfamily C, member 17:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for DNAJC17

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for DNAJC17 Gene

No ASD Table

Relevant External Links for DNAJC17 Gene

GeneLoc Exon Structure for
DNAJC17
ECgene alternative splicing isoforms for
DNAJC17

Expression for DNAJC17 Gene

mRNA expression in normal human tissues for DNAJC17 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues for DNAJC17 Gene

This gene is overexpressed in Peripheral blood mononuclear cells (20.4) and Lung (10.7).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for DNAJC17 Gene

SOURCE GeneReport for Unigene cluster for DNAJC17 Gene Hs.511069

genes like me logo Genes that share expressions with DNAJC17: view

Expression partners for DNAJC17 Gene

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for DNAJC17 Gene

Orthologs for DNAJC17 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for DNAJC17 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia DNAJC17 35
  • 89.14 (n)
  • 89.14 (a)
DNAJC17 36
  • 89 (a)
OneToOne
dog
(Canis familiaris)
Mammalia DNAJC17 35
  • 90.79 (n)
  • 90.13 (a)
DNAJC17 36
  • 90 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Dnajc17 35
  • 88.12 (n)
  • 89.11 (a)
Dnajc17 16
Dnajc17 36
  • 87 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia DNAJC17 35
  • 99.56 (n)
  • 99.34 (a)
DNAJC17 36
  • 99 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Dnajc17 35
  • 87.13 (n)
  • 89.77 (a)
platypus
(Ornithorhynchus anatinus)
Mammalia DNAJC17 36
  • 58 (a)
OneToOne
chicken
(Gallus gallus)
Aves DNAJC17 35
  • 71.95 (n)
  • 78.22 (a)
DNAJC17 36
  • 75 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia DNAJC17 36
  • 75 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia dnajc17 35
  • 66.89 (n)
  • 70.17 (a)
Str.10407 35
African clawed frog
(Xenopus laevis)
Amphibia MGC69064 35
zebrafish
(Danio rerio)
Actinopterygii dnajc17 35
  • 65.2 (n)
  • 67.57 (a)
zgc56091 35
dnajc17 36
  • 65 (a)
OneToOne
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.10984 35
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP003825 35
  • 53.4 (n)
  • 46.6 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG17187 35
  • 54.79 (n)
  • 46.37 (a)
CG17187 36
  • 42 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea dnj-22 36
  • 23 (a)
OneToOne
thale cress
(Arabidopsis thaliana)
eudicotyledons AT5G23590 35
  • 43.42 (n)
  • 32.47 (a)
rice
(Oryza sativa)
Liliopsida Os03g0136800 35
  • 40.27 (n)
  • 28.4 (a)
fission yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes cwf23 35
  • 45.2 (n)
  • 38.8 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 50 (a)
OneToOne
Species with no ortholog for DNAJC17:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for DNAJC17 Gene

ENSEMBL:
Gene Tree for DNAJC17 (if available)
TreeFam:
Gene Tree for DNAJC17 (if available)

Paralogs for DNAJC17 Gene

Paralogs for DNAJC17 Gene

Pseudogenes.org Pseudogenes for DNAJC17 Gene

genes like me logo Genes that share paralogs with DNAJC17: view

Variants for DNAJC17 Gene

Sequence variations from dbSNP and Humsavar for DNAJC17 Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type MAF
rs619526 -- 40,792,680(+) CAGGC(A/G)TGGTG intron-variant, upstream-variant-2KB
rs674229 -- 40,797,701(+) gccac(C/T)gcacc intron-variant
rs689873 -- 40,799,096(+) ggcgg(A/G)cgcct intron-variant
rs934783 -- 40,785,131(+) ACAAC(A/G)TCTCT intron-variant
rs1814415 -- 40,784,838(+) TACAC(A/C)TGTAA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for DNAJC17 Gene

Variant ID Type Subtype PubMed ID
nsv904101 CNV Loss 21882294
nsv904102 CNV Loss 21882294
nsv827306 CNV Loss 20364138

Relevant External Links for DNAJC17 Gene

HapMap Linkage Disequilibrium report
DNAJC17

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for DNAJC17 Gene

Disorders for DNAJC17 Gene

(1) University of Copenhagen DISEASES for DNAJC17 Gene

Relevant External Links for DNAJC17

Genetic Association Database (GAD)
DNAJC17
Human Genome Epidemiology (HuGE) Navigator
DNAJC17
genes like me logo Genes that share disorders with DNAJC17: view

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , Novoseek inferred disease relationships and Genatlas for DNAJC17 Gene

Publications for DNAJC17 Gene

  1. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey S.D. … Anand S. (Diabetes Care 2010) 3 48
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  5. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PMID: 17081983) Olsen J.V. … Mann M. (Cell 2006) 3 4

Products for DNAJC17 Gene

Sources for DNAJC17 Gene

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