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Aliases for DNAJC16 Gene

Aliases for DNAJC16 Gene

  • DnaJ (Hsp40) Homolog, Subfamily C, Member 16 2 3
  • KIAA0962 4

External Ids for DNAJC16 Gene

Summaries for DNAJC16 Gene

GeneCards Summary for DNAJC16 Gene

DNAJC16 (DnaJ (Hsp40) Homolog, Subfamily C, Member 16) is a Protein Coding gene. An important paralog of this gene is DNAJC18.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for DNAJC16 Gene

Genomics for DNAJC16 Gene

Genomic Location for DNAJC16 Gene

Start:
15,526,813 bp from pter
End:
15,592,379 bp from pter
Size:
65,567 bases
Orientation:
Plus strand

Genomic View for DNAJC16 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for DNAJC16 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for DNAJC16 Gene

Regulatory Elements for DNAJC16 Gene

Proteins for DNAJC16 Gene

  • Protein details for DNAJC16 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9Y2G8-DJC16_HUMAN
    Recommended name:
    DnaJ homolog subfamily C member 16
    Protein Accession:
    Q9Y2G8
    Secondary Accessions:
    • Q68D57
    • Q86X32
    • Q8N5P4

    Protein attributes for DNAJC16 Gene

    Size:
    782 amino acids
    Molecular mass:
    90591 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAA76806.2; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for DNAJC16 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for DNAJC16 Gene

Proteomics data for DNAJC16 Gene at MOPED

Post-translational modifications for DNAJC16 Gene

  • Modification sites at PhosphoSitePlus
  • Glycosylation at Asn631

Other Protein References for DNAJC16 Gene

No data available for DME Specific Peptides for DNAJC16 Gene

Domains for DNAJC16 Gene

Gene Families for DNAJC16 Gene

HGNC:
  • DNAJ :Heat shock proteins / DNAJ (HSP40)

Protein Domains for DNAJC16 Gene

Graphical View of Domain Structure for InterPro Entry

Q9Y2G8

UniProtKB/Swiss-Prot:

DJC16_HUMAN
Domain:
  • Contains 1 J domain.:
    • Q9Y2G8
  • Contains 1 thioredoxin domain.:
    • Q9Y2G8
genes like me logo Genes that share domains with DNAJC16: view

Function for DNAJC16 Gene

miRNA for DNAJC16 Gene

miRTarBase miRNAs that target DNAJC16

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for DNAJC16 Gene

Localization for DNAJC16 Gene

Subcellular locations from UniProtKB/Swiss-Prot for DNAJC16 Gene

Membrane; Single-pass type IV membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for DNAJC16 Gene COMPARTMENTS Subcellular localization image for DNAJC16 gene
Compartment Confidence
endoplasmic reticulum 3
extracellular 1
peroxisome 1
plasma membrane 1

Gene Ontology (GO) - Cellular Components for DNAJC16 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with DNAJC16: view

Pathways for DNAJC16 Gene

SuperPathways for DNAJC16 Gene

No Data Available

Interacting Proteins for DNAJC16 Gene

Gene Ontology (GO) - Biological Process for DNAJC16 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0045454 cell redox homeostasis IEA --
genes like me logo Genes that share ontologies with DNAJC16: view

No data available for Pathways by source for DNAJC16 Gene

Transcripts for DNAJC16 Gene

Unigene Clusters for DNAJC16 Gene

DnaJ (Hsp40) homolog, subfamily C, member 16:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for DNAJC16 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12a · 12b ^ 13a · 13b · 13c ^ 14a · 14b ^ 15 ^ 16a ·
SP1: - - - - -
SP2: - - - -
SP3: - -
SP4: - -
SP5:
SP6:
SP7:
SP8:

ExUns: 16b · 16c ^ 17
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:
SP8: - -

Relevant External Links for DNAJC16 Gene

GeneLoc Exon Structure for
DNAJC16
ECgene alternative splicing isoforms for
DNAJC16

Expression for DNAJC16 Gene

mRNA expression in normal human tissues for DNAJC16 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for DNAJC16 Gene

SOURCE GeneReport for Unigene cluster for DNAJC16 Gene Hs.655410

genes like me logo Genes that share expressions with DNAJC16: view

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for DNAJC16 Gene

Orthologs for DNAJC16 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for DNAJC16 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia DNAJC16 35
  • 99.57 (n)
  • 99.49 (a)
DNAJC16 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia DNAJC16 35
  • 90.2 (n)
  • 93.35 (a)
DNAJC16 36
  • 93 (a)
OneToOne
dog
(Canis familiaris)
Mammalia DNAJC16 35
  • 89.94 (n)
  • 93.09 (a)
DNAJC16 36
  • 93 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Dnajc16 35
  • 83.25 (n)
  • 89.51 (a)
Dnajc16 16
Dnajc16 36
  • 90 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia DNAJC16 36
  • 87 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 82 (a)
OneToMany
-- 36
  • 84 (a)
OneToMany
-- 36
  • 86 (a)
OneToMany
-- 36
  • 89 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Dnajc16 35
  • 85.04 (n)
  • 91.57 (a)
chicken
(Gallus gallus)
Aves DNAJC16 35
  • 73.19 (n)
  • 77.57 (a)
DNAJC16 36
  • 77 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100488071 35
  • 68.28 (n)
  • 72.93 (a)
zebrafish
(Danio rerio)
Actinopterygii dnajc16 35
  • 61.42 (n)
  • 61.42 (a)
DNAJC16 (1 of 2) 36
  • 60 (a)
OneToMany
DNAJC16 (2 of 2) 36
  • 55 (a)
OneToMany
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP001070 35
  • 43.75 (n)
  • 29.23 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG40178 35
  • 43.88 (n)
  • 26.99 (a)
CG40178 36
  • 23 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea dnj-8 35
  • 42.74 (n)
  • 30.94 (a)
dnj-8 36
  • 25 (a)
OneToOne
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes HLJ1 36
  • 30 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 40 (a)
OneToOne
Species with no ortholog for DNAJC16:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for DNAJC16 Gene

ENSEMBL:
Gene Tree for DNAJC16 (if available)
TreeFam:
Gene Tree for DNAJC16 (if available)

Paralogs for DNAJC16 Gene

Paralogs for DNAJC16 Gene

Selected SIMAP similar genes for DNAJC16 Gene using alignment to 5 proteins:

genes like me logo Genes that share paralogs with DNAJC16: view

Variants for DNAJC16 Gene

Sequence variations from dbSNP and Humsavar for DNAJC16 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs9298 -- 15,570,525(+) TTAAA(C/T)ATTTT utr-variant-3-prime, nc-transcript-variant
rs471727 -- 15,551,017(-) tggca(C/G)gtgcc intron-variant
rs472909 -- 15,566,277(-) AGAGT(C/T)CTTCT intron-variant, nc-transcript-variant
rs475614 -- 15,547,751(+) tccct(A/G)tttgc intron-variant
rs476049 -- 15,547,693(-) aggcc(A/G)aggtg intron-variant

Structural Variations from Database of Genomic Variants (DGV) for DNAJC16 Gene

Variant ID Type Subtype PubMed ID
nsv833536 CNV Loss 17160897

Relevant External Links for DNAJC16 Gene

HapMap Linkage Disequilibrium report
DNAJC16

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for DNAJC16 Gene

Disorders for DNAJC16 Gene

Relevant External Links for DNAJC16

Genetic Association Database (GAD)
DNAJC16
Human Genome Epidemiology (HuGE) Navigator
DNAJC16
genes like me logo Genes that share disorders with DNAJC16: view

No data available for UniProtKB/Swiss-Prot for DNAJC16 Gene

Publications for DNAJC16 Gene

  1. Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10231032) Nagase T. … Ohara O. (DNA Res. 1999) 3 4
  2. Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. (PMID: 12168954) Nakajima D. … Nagase T. (DNA Res. 2002) 3 4
  3. Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity. (PMID: 19773279) Hosgood H.D. … Lan Q. (Occup Environ Med 2009) 3 48
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  5. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4

Products for DNAJC16 Gene

Sources for DNAJC16 Gene

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