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DNAJC12 Gene

protein-coding   GIFtS: 53
GCID: GC10M069556

DnaJ (Hsp40) Homolog, Subfamily C, Member 12

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
DnaJ (Hsp40) Homolog, Subfamily C, Member 121 2
JDP12 3 5
J Domain Protein 11 2
J Domain-Containing Protein 12 3
DnaJ Homolog Subfamily C Member 122
J Domain Containing Protein 1 (JDP1)2

External Ids:    HGNC: 289081   Entrez Gene: 565212   Ensembl: ENSG000001081767   OMIM: 6060605   UniProtKB: Q9UKB33   

Export aliases for DNAJC12 gene to outside databases

Previous GC identifers: GC10M068902 GC10M069226 GC10M063555


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for DNAJC12 Gene:
This gene encodes a member of a subclass of the HSP40/DnaJ protein family. Members of this family of proteins are
associated with complex assembly, protein folding, and export. Two transcript variants encoding distinct isoforms
have been identified for this gene. (provided by RefSeq, Jul 2008)

GeneCards Summary for DNAJC12 Gene:
DNAJC12 (DnaJ (Hsp40) homolog, subfamily C, member 12) is a protein-coding gene. Diseases associated with DNAJC12 include polycystic liver disease, and intrahepatic cholangiocarcinoma. An important paralog of this gene is DNAJC17.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000010.11  NC_018921.2  NT_030059.14  
Regulatory elements:
   Regulatory transcription factor binding sites in the DNAJC12 gene promoter:
         COUP-TF1   NF-YA   COUP   HNF-4alpha2   LCR-F1   HNF-4alpha1   NF-YB   COUP-TF   CP1C   NF-Y   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidDNAJC12 promoter sequence
   Search Chromatin IP Primers for DNAJC12

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat DNAJC12


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q22.1   Ensembl cytogenetic band:  10q21.3   HGNC cytogenetic band: 10q21.3

DNAJC12 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DNAJC12 gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10M069556:  view genomic region     (about GC identifiers)

Start:
69,556,427 bp from pter      End:
69,597,937 bp from pter
Size:
41,511 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: DJC12_HUMAN, Q9UKB3 (See protein sequence)
Recommended Name: DnaJ homolog subfamily C member 12  
Size: 198 amino acids; 23415 Da
1 PDB 3D structure from and Proteopedia for DNAJC12:
2CTQ (3D)    
Secondary accessions: Q5JVQ1 Q9UKB2
Alternative splicing: 2 isoforms:  Q9UKB3-1   Q9UKB3-2   

Explore the universe of human proteins at neXtProt for DNAJC12: NX_Q9UKB3

Explore proteomics data for DNAJC12 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See DNAJC12 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_068572.1  NP_957714.1  

    ENSEMBL proteins: 
     ENSP00000225171   ENSP00000474215   ENSP00000473979   ENSP00000343575   ENSP00000474804  

    DNAJC12 Human Recombinant Protein Products:

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    DNAJC12 Assay Products:

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    Cloud-Clone Corp. ELISAs for DNAJC12
    Cloud-Clone Corp. CLIAs for DNAJC12


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    DNAJ: Heat shock proteins / DNAJ (HSP40)

    1 InterPro protein domain:
     IPR001623 DnaJ_domain

    Graphical View of Domain Structure for InterPro Entry Q9UKB3

    ProtoNet protein and cluster: Q9UKB3

    UniProtKB/Swiss-Prot: DJC12_HUMAN, Q9UKB3
    Similarity: Contains 1 J domain


    DNAJC12 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Phenotypes:
         1 GenomeRNAi human phenotype for DNAJC12:
     Increased gamma-H2AX phosphory 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for DNAJC12
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for DNAJC12

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for DNAJC12
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for DNAJC12

    miRNA
    Products:
        
    miRTarBase miRNAs that target DNAJC12:
    hsa-mir-26b-5p (MIRT029258)

    Block miRNA regulation of human, mouse, rat DNAJC12 using miScript Target Protectors
    5 qRT-PCR Assays for microRNAs that regulate DNAJC12:
    hsa-miR-23b hsa-miR-130a* hsa-miR-23a hsa-miR-944 hsa-miR-23c
    SwitchGear 3'UTR luciferase reporter plasmidDNAJC12 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for DNAJC12
    Predesigned siRNA for gene silencing in human, mouse, rat DNAJC12

    Gene Editing
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    Clone
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    GenScript: all cDNA clones in your preferred vector (see all 2): DNAJC12 (NM_021800)
    Sino Biological Human cDNA Clone for DNAJC12
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for DNAJC12
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DNAJC12

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for DNAJC12 
    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DNAJC12


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    cytosol2
    endoplasmic reticulum1
    extracellular1
    mitochondrion1

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Pathway & Disease-focused RT2 Profiler PCR Array including DNAJC12: 
              Heat Shock Proteins & Chaperones in human mouse rat

    Interactions:

        Search GeneGlobe Interaction Network for DNAJC12

    STRING Interaction Network Preview (showing 5 interactants - click image to see 14)

    Selected Interacting proteins for DNAJC12 (Q9UKB33 ENSP000002251714) via UniProtKB, MINT, STRING, and/or I2D (see all 16)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PAHP004393I2D: score=4 
    EEF1DP296923I2D: score=1 
    CDC5LENSP000003605324STRING: ENSP00000360532
    PRPF8ENSP000003043504STRING: ENSP00000304350
    CLPBENSP000002940534STRING: ENSP00000294053
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for DNAJC12 (DJC12)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for DNAJC12 gene (2 alternative transcripts): 
    NM_021800.2  NM_201262.1  

    Unigene Cluster for DNAJC12:

    DnaJ (Hsp40) homolog, subfamily C, member 12
    Hs.260720  [show with all ESTs]
    Unigene Representative Sequence: NM_021800
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000225171(uc001jnb.3) ENST00000483798 ENST00000480963 ENST00000339758(uc001jnc.3)
    ENST00000480180

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat DNAJC12 using miScript Target Protectors
    5 qRT-PCR Assays for microRNAs that regulate DNAJC12:
    hsa-miR-23b hsa-miR-130a* hsa-miR-23a hsa-miR-944 hsa-miR-23c
    SwitchGear 3'UTR luciferase reporter plasmidDNAJC12 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for DNAJC12
    Predesigned siRNA for gene silencing in human, mouse, rat DNAJC12
    Clone
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    OriGene clones in human, mouse for DNAJC12 (see all 12)
    OriGene ORF clones in mouse, rat for DNAJC12
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): DNAJC12 (NM_021800)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for DNAJC12
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DNAJC12
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for DNAJC12
    OriGene qSTAR qPCR primer pairs in human, mouse for DNAJC12
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat DNAJC12
      QuantiTect SYBR Green Assays in human, mouse, rat DNAJC12
      QuantiFast Probe-based Assays in human, mouse, rat DNAJC12

    Additional mRNA sequence: 

    AF176012.1 AF176013.1 AK289537.1 BC017018.1 CR457184.1 

    5 DOTS entries:

    DT.91765210  DT.95129154  DT.416346  DT.91976343  DT.121246995 

    Selected AceView cDNA sequences (see all 142):

    CR594852 F03969 NM_021800 T35837 BF794642 AA719166 BI861213 AF176013 
    BI438228 NM_201262 BI253314 AI025878 T95267 BM797707 Z45047 Z40804 
    AF176012 AL530912 BX091336 AA947853 AI392695 AW511355 AW875877 AA699661 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for DNAJC12 (see all 6)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b · 7c · 7d ^ 8a · 8b ^ 9a · 9b
    SP1:                          -     -     -                             -     -                           
    SP2:                          -     -     -           -                 -     -                           
    SP3:                          -     -     -                             -     -                           
    SP4:                          -     -                 -                                                   
    SP5:                                      -           -                                                   


    ECgene alternative splicing isoforms for DNAJC12

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    DNAJC12 expression in normal human tissues (normalized intensities)      DNAJC12 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    DNAJC12 Expression
    About this image


    DNAJC12 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Brain (Nervous System)    fully expand to see all 18 entries
             Thalamus
             Human Brain Vascular Smooth Muscle Cells (HBVSMC)   
             Olfactory Bulb   
     
     Smooth Muscle (Muscoskeletal System)
             Human Brain Vascular Smooth Muscle Cells (HBVSMC)   
     
     Blood (Hematopoietic System)
             Hematopoietic Stem Cells Hematopoietic Bone Marrow
    DNAJC12 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    DNAJC12 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.260720

    UniProtKB/Swiss-Prot: DJC12_HUMAN, Q9UKB3
    Tissue specificity: Expressed at high levels in brain, heart, and testis, and at reduced levels in kidney and
    stomach

        Pathway & Disease-focused RT2 Profiler PCR Array including DNAJC12: 
              Heat Shock Proteins & Chaperones in human mouse rat

    Primer
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    OriGene qPCR primer pairs and template standards for DNAJC12
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat DNAJC12
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    QuantiFast Probe-based Assays in human, mouse, rat DNAJC12
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DNAJC12

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for DNAJC12 gene from Selected species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Dnajc121 , 5 DnaJ (Hsp40) homolog, subfamily C, member 121, 5 80.13(n)1
    77.27(a)1
      10 (32.57 cM)5
    300451  NM_013888.31  NP_038916.11 
     633824435 
    chicken
    (Gallus gallus)
    Aves DNAJC121 DnaJ (Hsp40) homolog, subfamily C, member 12 70.92(n)
    63.27(a)
      423647  NM_001199530.1  NP_001186459.1 
    lizard
    (Anolis carolinensis)
    Reptilia DNAJC126
    DnaJ (Hsp40) homolog, subfamily C, member 12
    61(a)
    1 ↔ 1
    GL343215.1(1241059-1257710)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia LOC1004936581 dnaJ homolog subfamily C member 12-like 63.59(n)
    61.41(a)
      100493658  XM_002936857.2  XP_002936903.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.144562 Transcribed sequence with weak similarity to protein more 75.25(n)    BI672403.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta jdp1 jdp 48.98(n)
    40.22(a)
      43630  NM_170501.2  NP_733380.1 
    worm
    (Caenorhabditis elegans)
    Secernentea K07F5.166
    Protein K07F5.16 (K07F5.16) mRNA, complete cds
    32(a)
    1 ↔ 1
    IV(9864179-9864875) WBGene00010640


    ENSEMBL Gene Tree for DNAJC12 (if available)
    TreeFam Gene Tree for DNAJC12 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for DNAJC12 gene
    DNAJC172  
    3 SIMAP similar genes for DNAJC12 using alignment to 4 protein entries:     DJC12_HUMAN (see all proteins):
    JDP1    DNAJC10    DNAJC17

    DNAJC12 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for DNAJC12
    PGOHUM00000238888


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for DNAJC12 (see all 881)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs2074711251,2
    Cuntested169571283(+) CCACCA/GTCTTC 4 T M mis10--------
    rs114828741,2
    C--69556047(+) TTTTTT/-CCTCA 1 -- ds50012Minor allele frequency- -:0.25NA CSA 4
    rs1146148971,2
    C,F--69556080(+) TTAAAA/GTTAGG 1 -- ds50012Minor allele frequency- G:0.23WA NA 238
    rs1166997231,2
    C,F--69556276(+) GTGGCG/ATGTGC 1 -- ds50011Minor allele frequency- A:0.04WA 118
    rs795673801,2
    C,F--69556537(+) TAATAG/CAGATC 1 -- ut311Minor allele frequency- C:0.50WA 2
    rs169248821,2
    C,F,H--69556579(+) GTACAG/AAGATT 1 -- ut31 ese313Minor allele frequency- A:0.04NA NS EA WA 1512
    rs1877718961,2
    --69556725(+) TATGAG/TAACTG 1 -- ut310--------
    rs412992381,2
    C,F--69556732(+) ACTGAT/CTCAAG 1 -- ut312Minor allele frequency- C:0.06WA NA 238
    rs792975891,2
    C,F--69556802(+) AAGACA/GTAAAC 1 -- ut312Minor allele frequency- G:0.08CSA WA 122
    rs413075671,2
    C,F--69556814(+) AAGACT/CGCATG 1 -- ut311Minor allele frequency- C:0.03NA 120

    HapMap Linkage Disequilibrium report for DNAJC12 (69556427 - 69597937 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for DNAJC12:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv1143947CNV Insertion17803354
    esv1000438CNV Insertion20482838

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing DNAJC12
    DNA2.0 Custom Variant and Variant Library Synthesis for DNAJC12

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 606060    OMIM disorders: --

    8 diseases for DNAJC12:    About MalaCards
    polycystic liver disease    intrahepatic cholangiocarcinoma    cholangiocarcinoma    liver disease
    alzheimer's disease    malaria    cerebritis    breast cancer

    1 disease from the University of Copenhagen DISEASES database for DNAJC12:
    Polycystic liver disease

    DNAJC12 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015
    Genetic Association Database (GAD): DNAJC12
    Human Genome Epidemiology (HuGE) Navigator: DNAJC12 (2 documents)

    Export disorders for DNAJC12 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for DNAJC12 gene, integrated from 10 sources (see all 13):
    (articles sorted by number of sources associating them with DNAJC12)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Characterization of JDP genes, an evolutionarily conserved J domain- only protein family, from human and moths. (PubMed id 10760603)1, 2, 3 Lee J.... Chung J.H. (Biochim. Biophys. Acta 2000)
    2. Association studies of 23 positional/functional candidate genes on chromosome 10 in late-onset Alzheimer's disease. (PubMed id 17373700)1, 4 Morgan A.R....Williams J. (Am. J. Med. Genet. B Neuropsychiatr. Genet. 2007)
    3. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PubMed id 16385451)1, 4 Grupe A....Goate A. (Am. J. Hum. Genet. 2006)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)1, 2 Deloukas P.... Rogers J. (Nature 2004)
    6. JDP1 (DNAJC12/Hsp40) expression in breast cancer and its association with estrogen receptor status. (PubMed id 16391838)1, 9 De Bessa S.A....Nagai M.A. (Int. J. Mol. Med. 2006)
    7. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    8. N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PubMed id 22814378)2 Van Damme P....Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012)
    9. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    10. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (J. Biol. Chem. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 56521 HGNC: 28908 AceView: DNAJC12 Ensembl:ENSG00000108176 euGenes: HUgn56521
    ECgene: DNAJC12 H-InvDB: DNAJC12

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for DNAJC12 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
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    IP news from LifeMap Sciences, Inc.)
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    Patent Information for DNAJC12 gene:
    Search GeneIP for patents involving DNAJC12

    GeneCards and IP:
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