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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

DNAJC10 Gene

protein-coding   GIFtS: 55
GCID: GC02P183580

DnaJ (Hsp40) Homolog, Subfamily C, Member 10

  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
DnaJ (Hsp40) Homolog, Subfamily C, Member 101 2     PDIA192
MTHr2 3     DnaJ Homolog Subfamily C Member 102
ER-Resident Protein ERdj52 3     Endoplasmic Reticulum DNA J Domain-Containing Protein 52
JPDI2 5     J-Domain-Containing Protein Disulfide Isomerase-Like Protein2
ERDJ53 5     macrothioredoxin2
Member 191     Protein Disulfide Isomerase Family A, Member 192
Protein Disulfide Isomerase Family A1     Macrothioredoxin3
ERdj52     

External Ids:    HGNC: 246371   Entrez Gene: 544312   Ensembl: ENSG000000772327   OMIM: 6079875   UniProtKB: Q8IXB13   

Export aliases for DNAJC10 gene to outside databases

Previous GC identifers: GC02P183784 GC02P183406 GC02P183289 GC02P175438


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for DNAJC10 Gene:
This gene encodes an endoplasmic reticulum co-chaperone which is part of the endoplasmic reticulum-associated
degradation complex involved in recognizing and degrading misfolded proteins. The encoded protein reduces
incorrect disulfide bonds in misfolded glycoproteins. Alternatively spliced transcript variants encoding multiple
isoforms have been observed for this gene. (provided by RefSeq, Oct 2012)

GeneCards Summary for DNAJC10 Gene: 
DNAJC10 (DnaJ (Hsp40) homolog, subfamily C, member 10) is a protein-coding gene. Diseases associated with DNAJC10 include neuroblastoma. GO annotations related to this gene include electron carrier activity and heat shock protein binding. An important paralog of this gene is PDIA6.

UniProtKB/Swiss-Prot: DJC10_HUMAN, Q8IXB1
Function: This endoplasmic reticulum co-chaperone may play a role in protein folding and translocation across the
endoplasmic reticulum membrane. May act as a co-chaperone for HSPA5

Gene Wiki entry for DNAJC10 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000002.11  NC_018913.2  NT_005403.17  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the DNAJC10 gene promoter:
         GR   AML1a   RelA   Evi-1   FOXL1   CREB   MZF-1   deltaCREB   GR-alpha   Ik-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidDNAJC10 promoter sequence
   Search SABiosciences Chromatin IP Primers for DNAJC10

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DNAJC10


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q32.1   Ensembl cytogenetic band:  2q32.1   HGNC cytogenetic band: 2q32.1

DNAJC10 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DNAJC10 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P183580:  view genomic region     (about GC identifiers)

Start:
183,580,999 bp from pter      End:
183,644,334 bp from pter
Size:
63,336 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: DJC10_HUMAN, Q8IXB1 (See protein sequence)
Recommended Name: DnaJ homolog subfamily C member 10 precursor  
Size: 793 amino acids; 91080 Da
Subunit: Interacts with HSPA5 via its J domain
Subcellular location: Secreted (Potential). Endoplasmic reticulum lumen (By similarity)
Sequence caution: Sequence=BAB55121.1; Type=Erroneous initiation; Sequence=BAC11281.1; Type=Erroneous initiation;
Secondary accessions: Q17RJ6 Q4ZG06 Q53QT7 Q6UWZ6 Q86T61 Q8NC82 Q8TD87 Q96K38 Q96K44 Q96K54
Q9NSY6
Alternative splicing: 2 isoforms:  Q8IXB1-1   Q8IXB1-2   

Explore the universe of human proteins at neXtProt for DNAJC10: NX_Q8IXB1

Explore proteomics data for DNAJC10 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8IXB1

  • DNAJC10 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    DNAJC10 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001258510.1  NP_061854.1  

    ENSEMBL proteins: 
     ENSP00000264065   ENSP00000389483   ENSP00000400096   ENSP00000441560  

    Human Recombinant Protein Products for DNAJC10: 
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    Cloud-Clone Corp. Proteins for DNAJC10 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region ----
    GO:0005783endoplasmic reticulum IDA12411443
    GO:0005788endoplasmic reticulum lumen IDA--
    GO:0034663endoplasmic reticulum chaperone complex IDA18400946

    DNAJC10 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    DNAJ: Heat shock proteins / DNAJ (HSP40)
    PDI: Protein disulfide isomerases

    5/6 InterPro protein domains (see all 6):
     IPR005746 Thioredoxin
     IPR012336 Thioredoxin-like_fold
     IPR021170 DnaJ_homolog_subfam-C
     IPR001623 DnaJ_domain
     IPR013766 Thioredoxin_domain

    Graphical View of Domain Structure for InterPro Entry Q8IXB1

    ProtoNet protein and cluster: Q8IXB1

    1 Blocks protein domain: IPB006662 Thioredoxin type domain

    UniProtKB/Swiss-Prot: DJC10_HUMAN, Q8IXB1
    Similarity: Contains 1 J domain
    Similarity: Contains 4 thioredoxin domains


    DNAJC10 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: DJC10_HUMAN, Q8IXB1
    Function: This endoplasmic reticulum co-chaperone may play a role in protein folding and translocation across the
    endoplasmic reticulum membrane. May act as a co-chaperone for HSPA5
    Induction: By endoplasmic reticulum stress

         Gene Ontology (GO): 5/10 molecular function terms (GO ID links to tree view) (see all 10):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001671ATPase activator activity ISS--
    GO:0005515protein binding IPI19706418
    GO:0009055electron carrier activity IEA--
    GO:0015035protein disulfide oxidoreductase activity ISS--
    GO:0015036disulfide oxidoreductase activity ISS--
         
    DNAJC10 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for DNAJC10:
     Decreased POU5F1-GFP protein e  Increased gamma-H2AX phosphory 

         6 MGI mutant phenotypes (inferred from 3 alleles(MGI details for Dnajc10):
     cellular  digestive/alimentary  endocrine/exocrine gland  homeostasis/metabolism  no phenotypic analysis 
     reproductive system 

    DNAJC10 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-outs for DNAJC10: Dnajc10tm1Lex Dnajc10tm1Tiw

       inGenious Targeting Laboratory - Custom generated mouse model solutions for DNAJC10 
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    SwitchGear 3'UTR luciferase reporter plasmidDNAJC10 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for DNAJC10 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Protein processing in endoplasmic reticulum
    Protein processing in endoplasmic reticulum

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    1         Kegg Pathway  (Kegg details for DNAJC10):
        Protein processing in endoplasmic reticulum


    DNAJC10 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for DNAJC10

    STRING Interaction Network Preview (showing 5 interactants - click image to see 10)

    5/48 Interacting proteins for DNAJC10 (Q8IXB12, 3 ENSP000002640654) via UniProtKB, MINT, STRING, and/or I2D (see all 48)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MAGEA11P433642, 3, ENSP000003473584MINT-66172 I2D: score=4 STRING: ENSP00000347358
    HSPA5P110213, ENSP000003241734I2D: score=2 STRING: ENSP00000324173
    FOXRED2Q8IWF23, ENSP000002161874I2D: score=1 STRING: ENSP00000216187
    MAP1LC3BQ9GZQ83, ENSP000002686074I2D: score=1 STRING: ENSP00000268607
    GABARAPO951663I2D: score=2 
    About this table

    Gene Ontology (GO): 5/8 biological process terms (GO ID links to tree view) (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001933negative regulation of protein phosphorylation IDA19122239
    GO:0006662glycerol ether metabolic process IEA--
    GO:0030433ER-associated protein catabolic process IMP18400946
    GO:0032781positive regulation of ATPase activity ISS--
    GO:0034975protein folding in endoplasmic reticulum IDA--

    DNAJC10 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for DNAJC10 (DJC10)

    Search CenterWatch for drugs/clinical trials and news about DNAJC10 / DJC10

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for DNAJC10 gene (2 alternative transcripts): 
    NM_001271581.1  NM_018981.2  

    Unigene Cluster for DNAJC10:

    DnaJ (Hsp40) homolog, subfamily C, member 10
    Hs.516632  [show with all ESTs]
    Unigene Representative Sequence: NR_073366
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000264065(uc002uow.1 uc002uox.1 uc002uoy.1 uc002uoz.1 uc010fro.1)
    ENST00000491074 ENST00000469118 ENST00000418559 ENST00000494462 ENST00000459930
    ENST00000444005 ENST00000537515
    miRNA
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    hsa-miR-610 hsa-miR-3143 hsa-miR-548aa hsa-miR-543
    SwitchGear 3'UTR luciferase reporter plasmidDNAJC10 3' UTR sequence
    Inhib. RNA
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    Additional mRNA sequence: 

    AF038503.1 AF314529.1 AF490904.1 AK027450.1 AK027647.1 AK027696.1 AK027701.2 AK074905.1 
    AK298138.1 AL137648.1 AL832267.1 AL832632.2 AL832646.3 AY089971.1 AY358577.1 BC034713.1 
    BC070034.1 BC107425.1 BC117299.1 BC126168.1 NR_073365.1 NR_073366.1 NR_073367.1 

    17 DOTS entries:

    DT.114144  DT.92453636  DT.95373815  DT.100028239  DT.100792982  DT.101983062  DT.121004296  DT.95265637 
    DT.309872  DT.121004308  DT.121004324  DT.121004336  DT.121004354  DT.121004378  DT.95373817  DT.95373819 
    DT.91764817 

    24/297 AceView cDNA sequences (see all 297):

    AW591459 AI801752 AI619651 AI805381 BI522423 NM_018981 AI635655 AA902132 
    BG282948 AI824499 C02316 BM903629 BQ109538 BQ225560 AI923380 AI917520 
    BQ434966 AW517541 AK074905 BQ044964 BU072365 BI793203 AV647116 AI864640 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for DNAJC10    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21 ^ 22 ^ 23 ^ 24 ^
    SP1:                                                  -                       -                                                                                 
    SP2:                                                  -                       -                                         -                                       
    SP3:                                                                                                                                                            

    ExUns: 25 ^ 26a · 26b
    SP1:                  
    SP2:                  
    SP3:                  


    ECgene alternative splicing isoforms for DNAJC10

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    DNAJC10 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TAGTTGTTTA
    DNAJC10 Expression
    About this image


    See DNAJC10 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for DNAJC10

    SOURCE GeneReport for Unigene cluster: Hs.516632
        SABiosciences Expression via Pathway-Focused PCR Arrays including DNAJC10: 
              Unfolded Protein Response in human mouse rat
              Heat Shock Proteins & Chaperones in human mouse rat

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DNAJC10

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for DNAJC10 gene from 6/15 species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Dnajc101 , 5 DnaJ (Hsp40) homolog, subfamily C, member 101, 5 87.31(n)1
    90.29(a)1
      2 (48.05 cM)5
    668611  NM_024181.21  NP_077143.21 
     803154665 
    chicken
    (Gallus gallus)
    Aves DNAJC101 DnaJ (Hsp40) homolog, subfamily C, member 10 77.45(n)
    76.52(a)
      424115  XM_421968.2  XP_421968.2 
    lizard
    (Anolis carolinensis)
    Reptilia DNAJC106
    DnaJ (Hsp40) homolog, subfamily C, member 10
    73(a)
    1 ↔ 1
    GL343221.1(2060267-2100738)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.134582 Transcribed sequence with weak similarity to protein more 76(n)    BX732306.1 
    zebrafish
    (Danio rerio)
    Actinopterygii CD594266.12   -- 74.1(n)    CD594266.1 
    worm
    (Caenorhabditis elegans)
    Secernentea dnj-271 Protein DNJ-27 51.34(n)
    43.86(a)
      173065  NM_001047239.2  NP_001040704.1 


    ENSEMBL Gene Tree for DNAJC10 (if available)
    TreeFam Gene Tree for DNAJC10 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for DNAJC10 gene
    PDIA62  TXNDC52  BLOC1S5-TXNDC52  PDIA52  
    9 SIMAP similar genes for DNAJC10 using alignment to 5 protein entries:     DJC10_HUMAN (see all proteins):
    DNAJC1    DNAJB6    DNAJC17    DNAJB5    DNAJA4    DNAJB3
    DNAJC24    ZCSL3    PDIA3

    DNAJC10 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1339 SNPs in DNAJC10 are shown (see all 1339)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs610709561,2
    C,F--183578949(+) TTCATG/AAAGCT 5 -- us2k16Minor allele frequency- A:0.06NA CSA WA EA 364
    rs767578291,2
    C,F--183578968(+) TTTTCC/TGTGTG 5 -- us2k12Minor allele frequency- T:0.07NA EA 240
    rs1443677821,2
    --183578969(+) TTTCCA/GTGTGT 5 -- us2k10--------
    rs1171543511,2
    F--183579057(+) TGGGTG/CATCTG 5 -- us2k11Minor allele frequency- C:0.01EA 120
    rs755739581,2
    F--183579142(+) TGATCT/CAGGAA 5 -- us2k11Minor allele frequency- C:0.06WA 118
    rs1848446941,2
    --183579214(+) AGTGGA/GTAGTA 5 -- us2k10--------
    rs1866053071,2
    --183579224(+) ATTCAG/TCCATA 5 -- us2k10--------
    rs1913888791,2
    --183579350(+) GCAGTA/GGTGTG 5 -- us2k10--------
    rs1478514721,2
    C--183579385(+) CTCCCG/TGGTTC 5 -- us2k10--------
    rs1128393561,2
    C--183579417(+) AGTAGC/TTGGGA 5 -- us2k11Minor allele frequency- T:0.50CSA 2

    HapMap Linkage Disequilibrium report for DNAJC10 (183580999 - 183644334 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 7 variations for DNAJC10:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv875483CNV Loss21882294
    dgv4378n71CNV Loss21882294
    nsv10204CNV Loss18304495
    esv34847CNV Gain17911159
    nsv820264CNV Gain19587683
    essv8969CNV CNV17122850
    dgv1276e1CNV Complex17122850

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 607987    OMIM disorders: --

    2 diseases for DNAJC10:    About MalaCards
    neuroblastoma    


    DNAJC10 for disorders           About GeneDecksing


    Export disorders for DNAJC10 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for DNAJC10 gene, integrated from 9 sources (see all 34):
    (articles sorted by number of sources associating them with DNAJC10)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. ERdj5, an endoplasmic reticulum (ER)-resident protein containing DnaJ and thioredoxin domains, is expressed in secretory cells or following ER stress. (PubMed id 12411443)1, 2, 3 Cunnea P.M.... Spyrou G. (2003)
    2. Cloning and identification of a novel cDNA which encodes a putative protein with a DnaJ domain and a thioredoxin active motif, human macrothioredoxin. (PubMed id 14587667)1, 2, 9 Gu S.-H.... Mao Y.-M. (2003)
    3. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)1, 2 Hillier L.W....Wilson R.K. (2005)
    4. Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PubMed id 16303743)1, 2 Otsuki T....Isogai T. (2005)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    7. JPDI, a novel endoplasmic reticulum-resident protein containing both a BiP-interacting J-domain and thioredoxin-like motifs. (PubMed id 12446677)1, 3 Hosoda A....Kohno K. (2003)
    8. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
    9. ERdj4 and ERdj5 Are Required for Endoplasmic Reticulum-associated Protein Degradation of Misfolded Surfactant Protein C. (PubMed id 18400946)1, 9 Dong M....Weaver T.E. (2008)
    10. ERdj5 is required as a disulfide reductase for degradation of misfolded proteins in the ER. (PubMed id 18653895)1, 9 Ushioda R....Nagata K. (2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 54431 HGNC: 24637 AceView: DNAJC10 Ensembl:ENSG00000077232 euGenes: HUgn54431
    ECgene: DNAJC10 Kegg: 54431 H-InvDB: DNAJC10

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for DNAJC10 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for DNAJC10 gene:
    Search GeneIP for patents involving DNAJC10

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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