Aliases for DNAJB9 Gene
External Ids for DNAJB9 Gene
Previous Symbols for DNAJB9 Gene
This gene is a member of the J protein family. J proteins function in many cellular processes by regulating the ATPase activity of 70 kDa heat shock proteins. This gene is a member of the type 2 subgroup of DnaJ proteins. The encoded protein is localized to the endoplasmic reticulum. This protein is induced by endoplasmic reticulum stress and plays a role in protecting stressed cells from apoptosis. [provided by RefSeq, Dec 2010]
GeneCards Summary for DNAJB9 Gene
DNAJB9 (DnaJ (Hsp40) Homolog, Subfamily B, Member 9) is a Protein Coding gene. Among its related pathways are Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein and Unfolded Protein Response. GO annotations related to this gene include misfolded protein binding. An important paralog of this gene is DNAJB7.
UniProtKB/Swiss-Prot for DNAJB9 Gene
Involved in endoplasmic reticulum-associated degradation (ERAD) of misfolded proteins. Acts as a co-chaperone with an Hsp70 protein.