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DNAJB9 Gene

protein-coding   GIFtS: 54
GCID: GC07P108210

DnaJ (Hsp40) Homolog, Subfamily B, Member 9


(Previous symbol: MDG1)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
DnaJ (Hsp40) Homolog, Subfamily B, Member 91 2     MDG-12
MDG11 2 3 5     MST0492
Endoplasmic Reticulum DNA J Domain-Containing Protein 42 3     MSTP0492
Microvascular Endothelial Differentiation Gene 1 Protein2 3     DnaJ Homolog Subfamily B Member 92
ERdj42 3     Endoplasmic Reticulum DnaJ Homolog 42
ER-Resident Protein ERdj42 3     Mdg-13

External Ids:    HGNC: 69681   Entrez Gene: 41892   Ensembl: ENSG000001285907   OMIM: 6026345   UniProtKB: Q9UBS33   

Export aliases for DNAJB9 gene to outside databases

Previous GC identifers: GC07P106694 GC07P107756 GC07P107770 GC07P107804 GC07P107997 GC07P102578


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for DNAJB9 Gene:
This gene is a member of the J protein family. J proteins function in many cellular processes by regulating the
ATPase activity of 70 kDa heat shock proteins. This gene is a member of the type 2 subgroup of DnaJ proteins. The
encoded protein is localized to the endoplasmic reticulum. This protein is induced by endoplasmic reticulum
stress and plays a role in protecting stressed cells from apoptosis. (provided by RefSeq, Dec 2010)

GeneCards Summary for DNAJB9 Gene:
DNAJB9 (DnaJ (Hsp40) homolog, subfamily B, member 9) is a protein-coding gene. GO annotations related to this gene include misfolded protein binding. An important paralog of this gene is DNAJB4.

UniProtKB/Swiss-Prot: DNJB9_HUMAN, Q9UBS3
Function: Involved in endoplasmic reticulum-associated degradation (ERAD) of misfolded proteins. Acts as a
co-chaperone with an Hsp70 protein

Gene Wiki entry for DNAJB9 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Regulatory transcription factor binding sites in the DNAJB9 gene promoter:
         CBF-A   CBF-B   POU2F1   POU2F1a   Pax-2   Pax-2a   Nkx2-5   CBF(2)   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 3): DNAJB9 promoter sequence
   Search Chromatin IP Primers for DNAJB9

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat DNAJB9


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q31|14q24.2-q24.3   Ensembl cytogenetic band:  7q31.1   HGNC cytogenetic band: 7q31

DNAJB9 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DNAJB9 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07P108210:  view genomic region     (about GC identifiers)

Start:
108,210,012 bp from pter      End:
108,215,294 bp from pter
Size:
5,283 bases      Orientation:
plus strand

1 alternative location:
Chr7+,CRA_TCAG 107,577,403-107,582,508     

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: DNJB9_HUMAN, Q9UBS3 (See protein sequence)
Recommended Name: DnaJ homolog subfamily B member 9 precursor  
Size: 223 amino acids; 25518 Da
Subunit: Interacts with DERL1 (By similarity)
1 PDB 3D structure from and Proteopedia for DNAJB9:
2CTR (3D)    

Explore the universe of human proteins at neXtProt for DNAJB9: NX_Q9UBS3

Explore proteomics data for DNAJB9 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See DNAJB9 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_036460.1  
    ENSEMBL proteins: 
     ENSP00000249356  
    Reactome Protein details: Q9UBS3

    DNAJB9 Human Recombinant Protein Products:

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    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for DNAJB9

     
    Search eBioscience for Proteins for DNAJB9 

     
    antibodies-online proteins for DNAJB9 (7 products) 

     
    antibodies-online peptides for DNAJB9

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    DNAJ: Heat shock proteins / DNAJ (HSP40)

    2 InterPro protein domains:
     IPR001623 DnaJ_domain
     IPR018253 DnaJ_domain_CS

    Graphical View of Domain Structure for InterPro Entry Q9UBS3

    ProtoNet protein and cluster: Q9UBS3

    UniProtKB/Swiss-Prot: DNJB9_HUMAN, Q9UBS3
    Similarity: Contains 1 J domain


    Find genes that share domains with DNAJB9           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: DNJB9_HUMAN, Q9UBS3
    Function: Involved in endoplasmic reticulum-associated degradation (ERAD) of misfolded proteins. Acts as a
    co-chaperone with an Hsp70 protein

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI19815549
    GO:0051787misfolded protein binding IDA18400946
         
    Find genes that share ontologies with DNAJB9           About GenesLikeMe


    Phenotypes:
         2 GenomeRNAi human phenotypes for DNAJB9:
     Increased G1 DNA content  Increased cell size 

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for DNAJB9

    miRNA
    Products:
        
    miRTarBase miRNAs that target DNAJB9:
    hsa-mir-877-5p (MIRT037350), hsa-mir-335-5p (MIRT017907), hsa-mir-32-5p (MIRT028383), hsa-mir-215-5p (MIRT024579), hsa-mir-320a (MIRT044516), hsa-mir-505-3p (MIRT040986), hsa-mir-192-5p (MIRT026471)

    Block miRNA regulation of human, mouse, rat DNAJB9 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate DNAJB9 (see all 53):
    hsa-miR-193a-3p hsa-miR-429 hsa-let-7d hsa-miR-106a hsa-miR-513a-5p hsa-miR-25 hsa-miR-519a hsa-miR-374c
    SwitchGear 3'UTR luciferase reporter plasmidDNAJB9 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for DNAJB9
    Predesigned siRNA for gene silencing in human, mouse, rat DNAJB9

    Gene Editing
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    Clone
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    GenScript: all cDNA clones in your preferred vector: DNAJB9 (NM_012328)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for DNAJB9
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DNAJB9
    Addgene plasmids for DNAJB9 

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DNAJB9


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    DNJB9_HUMAN, Q9UBS3: Endoplasmic reticulum lumen (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    endoplasmic reticulum4
    nucleus4
    extracellular3
    cytoskeleton1
    cytosol1

    Gene Ontology (GO): Selected cellular component terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005730nucleolus ISS--
    GO:0005737cytoplasm ISS--
    GO:0005783endoplasmic reticulum IDA--
    GO:0005788endoplasmic reticulum lumen IEA--
    GO:0005789endoplasmic reticulum membrane TAS--

    Find genes that share ontologies with DNAJB9           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for DNAJB9 About    
    See pathways by source

    SuperPathContained pathways About
    1Unfolded Protein Response
    Unfolded Protein Response0.61
    Activation of Chaperone Genes by XBP1(S)0.59
    Activation of Chaperones by IRE1alpha0.61
    2Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
    Metabolism of proteins0.30


    Find genes that share SuperPaths with DNAJB9           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Reactome Pathway for DNAJB9
        XBP1(S) activates chaperone genes


        Pathway & Disease-focused RT2 Profiler PCR Arrays including DNAJB9: 
              Cellular Stress Responses in human mouse rat
              Unfolded Protein Response in human mouse rat
              Heat Shock Proteins & Chaperones in human mouse rat

    Interactions:

        GeneGlobe Interaction Network for DNAJB9

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for DNAJB9 (Q9UBS32, 3 ENSP000002493564) via UniProtKB, MINT, STRING, and/or I2D (see all 40)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MYL6P606602, 3, ENSP000002934224MINT-65685 I2D: score=4 STRING: ENSP00000293422
    PLK1P533502, 3MINT-65684 I2D: score=5 
    SLC16A8O959072, 3MINT-65683 I2D: score=5 
    DYNLL1P631672, 3MINT-65686 I2D: score=4 
    RFKQ969G62, 3MINT-65688 I2D: score=4 
    About this table

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006987activation of signaling protein activity involved in unfolded protein response TAS--
    GO:0030433ER-associated ubiquitin-dependent protein catabolic process IMP18400946
    GO:0030968endoplasmic reticulum unfolded protein response TAS--
    GO:0044267cellular protein metabolic process TAS--

    Find genes that share ontologies with DNAJB9           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for DNAJB9 (DNJB9)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for DNAJB9 gene: 
    NM_012328.2  

    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000249356(uc003vfn.3) ENST00000491582 ENST00000465725
    miRNA
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    Block miRNA regulation of human, mouse, rat DNAJB9 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate DNAJB9 (see all 53):
    hsa-miR-193a-3p hsa-miR-429 hsa-let-7d hsa-miR-106a hsa-miR-513a-5p hsa-miR-25 hsa-miR-519a hsa-miR-374c
    SwitchGear 3'UTR luciferase reporter plasmidDNAJB9 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for DNAJB9
    Predesigned siRNA for gene silencing in human, mouse, rat DNAJB9
    Clone
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DNAJB9
    Addgene plasmids for DNAJB9 
    Primer
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    OriGene qPCR primer pairs and template standards for DNAJB9
    OriGene qSTAR qPCR primer pairs in human, mouse for DNAJB9
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat DNAJB9
      QuantiTect SYBR Green Assays in human, mouse, rat DNAJB9
      QuantiFast Probe-based Assays in human, mouse, rat DNAJB9

    Selected AceView cDNA sequences (see all 260):

    AI457520 CB321773 BP369159 BM975416 CR613647 AI889643 AI627998 AW612387 
    AI683522 AW779606 AI814803 AI299527 AU280257 BM700341 AA815051 BQ773823 
    AI281873 BG572731 AI351842 AA344966 BM263441 CA311041 AW194852 AA398180 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for DNAJB9    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b ^ 3a · 3b
    SP1:                                -               
    SP2:                    -           -               
    SP3:                                                


    ECgene alternative splicing isoforms for DNAJB9

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    DNAJB9 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AAACTGTATA
    DNAJB9 Expression
    About this image


    DNAJB9 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 10) fully expand
     
     Brain (Nervous System)    fully expand to see all 8 entries
             Cerebral Cortex
     
     Neural Tube (Nervous System)    fully expand to see all 3 entries
             Metencephalon
     
     Liver (Hepatobiliary System)
             Hepatocytes Liver Lobule
     
     Bone (Muscoskeletal System)
             Bone Marrow
     
     Trophoblast (Extraembryonic Tissues)
             Trophoblast Cells Trophoblast
    DNAJB9 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    DNAJB9 Protein Expression
        Pathway & Disease-focused RT2 Profiler PCR Arrays including DNAJB9: 
              Cellular Stress Responses in human mouse rat
              Unfolded Protein Response in human mouse rat
              Heat Shock Proteins & Chaperones in human mouse rat

    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DNAJB9

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for DNAJB9 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Dnajb91 , 5 DnaJ (Hsp40) homolog, subfamily B, member 91, 5 91.44(n)1
    94.14(a)1
      12 (20.71 cM)5
    273621  NM_013760.41  NP_038788.21 
     442058975 
    chicken
    (Gallus gallus)
    Aves DNAJB91 DnaJ (Hsp40) homolog, subfamily B, member 9 76.74(n)
    75.81(a)
      417783  NM_001030735.1  NP_001025906.1 
    lizard
    (Anolis carolinensis)
    Reptilia DNAJB96
    DnaJ (Hsp40) homolog, subfamily B, member 9
    78(a)
    1 ↔ 1
    1(133496858-133502504)
    African clawed frog
    (Xenopus laevis)
    Amphibia BC046936.12   -- 82.43(n)    BC046936.1 
    zebrafish
    (Danio rerio)
    Actinopterygii dnajb9a1 DnaJ (Hsp40) homolog, subfamily B, member 9a 69.33(n)
    69.01(a)
      574005  NM_001025184.1  NP_001020355.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG71306
    --
    27(a)
    1 ↔ 1
    3L(22068156-22068856)


    ENSEMBL Gene Tree for DNAJB9 (if available)
    TreeFam Gene Tree for DNAJB9 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for DNAJB9 gene
    DNAJB42  DNAJB52  DNAJB132  DNAJB22  DNAJB62  DNAJB12  DNAJB72  DNAJC5B2  
    DNAJC52  DNAJC5G2  DNAJB82  
    7 SIMAP similar genes for DNAJB9 using alignment to 2 protein entries:     DNJB9_HUMAN (see all proteins):
    DNAJB12    DNAJB6    DNAJB4    DNAJA3    DNAJB5    DNAJB1
    WUGSC

    Find genes that share paralogs with DNAJB9           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for DNAJB9 (see all 84)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs617499531,2
    C,F--108212174(+) AAATGG/ACTACT 2 /T /A mis12Minor allele frequency- A:0.00NA EU 5157
    rs789483601,2
    C--108212184(+) TCCCCA/CGTCAA 2 Q P mis10--------
    rs1504065851,2
    C--108212243(+) CCTCAA/GAAAGC 2 K E mis11Minor allele frequency- G:0.00NA 4498
    rs1418273021,2
    C--108212288(+) CAGAGC/TGCCAA 2 R C mis11Minor allele frequency- T:0.00NA 4542
    rs1462866251,2
    C--108212298(+) AATCAA/GGAAGG 2 K R mis11Minor allele frequency- G:0.00NA 4542
    rs10436151,2
    C,F,H--108212353(+) AGCCCG/AGATGC 2 /P syn1 ese335Minor allele frequency- A:0.47EA MN NA NS WA CSA EU 10189
    rs1115905961,2
    F--108212655(+) CTGTTG/CCTTCT 1 -- int12Minor allele frequency- C:0.04CSA WA 120
    rs556876341,2
    C,F--108212692(+) AAAATT/CCTTAT 1 -- int12Minor allele frequency- C:0.21WA 120
    rs1842439331,2
    --108212787(+) TTGATC/TTGCTT 1 -- int10--------
    rs1162332001,2
    C--108212848(+) CAGACG/TAGCTC 1 -- int10--------

    HapMap Linkage Disequilibrium report for DNAJB9 (108210012 - 108215294 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for DNAJB9: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing DNAJB9
    DNA2.0 Custom Variant and Variant Library Synthesis for DNAJB9

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

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    OMIM gene information: 602634    OMIM disorders: --


    Find genes that share disorders with DNAJB9           About GenesLikeMe

    Genetic Association Database (GAD): DNAJB9
    Human Genome Epidemiology (HuGE) Navigator: DNAJB9 (1 document)

    Export disorders for DNAJB9 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for DNAJB9 gene, integrated from 10 sources (see all 43):
    (articles sorted by number of sources associating them with DNAJB9)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. ERdj4 and ERdj5 are required for endoplasmic reticulum-associated protein degradation of misfolded surfactant protein C. (PubMed id 18400946)1, 2, 9 Dong M....Weaver T.E. (Mol. Biol. Cell 2008)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (Genome Res. 2003)
    4. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (Genome Res. 2001)
    5. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)1, 2 Zhang Q.-H.... Chen Z. (Genome Res. 2000)
    6. Mammalian HSP40/DNAJ homologs: cloning of novel cDNAs and a proposal for their classification and nomenclature. (PubMed id 11147971)1, 3 Ohtsuka K. and Hata M. (Cell Stress Chaperones 2000)
    7. Assignment of the microvascular endothelial differentiation gene 1 (MDG1) to human chromosome band 14q24.2--&gt;q24.3 by fluorescence in situ hybridization. (PubMed id 9533036)1, 3 PrAPls F....Rautenstrauss B. (Cytogenet. Cell Genet. 1997)
    8. Identification and characterization of a novel endoplasmic reticulum (ER) DnaJ homologue, which stimulates ATPase activity of BiP in vitro and is induced by ER stress. (PubMed id 11836248)1, 9 Shen Y....Hendershot L.M. (J. Biol. Chem. 2002)
    9. HLA-B35 upregulates endothelin-1 and downregulates endothelial nitric oxide synthase via endoplasmic reticulum stress response in endothelial cells. (PubMed id 20335527)1, 9 Lenna S....Scorza R. (J. Immunol. 2010)
    10. XBP-1 regulates a subset of endoplasmic reticulum resident chaperone genes in the unfolded protein response. (PubMed id 14559994)1, 9 Lee A.H....Glimcher L.H. (Mol. Cell. Biol. 2003)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 4189 HGNC: 6968 AceView: DNAJB9 Ensembl:ENSG00000128590 euGenes: HUgn4189
    ECgene: DNAJB9 H-InvDB: DNAJB9

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for DNAJB9 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for DNAJB9 gene:
    Search GeneIP for patents involving DNAJB9

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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