Aliases for DNAJB8 Gene
External Ids for DNAJB8 Gene
Previous GeneCards Identifiers for DNAJB8 Gene
The protein encoded by this gene belongs to the DNAJ/HSP40 family of proteins that regulate chaperone activity. This family member suppresses aggregation and toxicity of polyglutamine proteins, and the C-terminal tail is essential for this activity. It has been implicated as a cancer-testis antigen and as a cancer stem-like cell antigen involved in renal cell carcinoma. [provided by RefSeq, Jun 2012]
GeneCards Summary for DNAJB8 Gene
DNAJB8 (DnaJ (Hsp40) Homolog, Subfamily B, Member 8) is a Protein Coding gene. Diseases associated with DNAJB8 include renal cell carcinoma. GO annotations related to this gene include protein binding involved in protein folding. An important paralog of this gene is DNAJB7.
UniProtKB/Swiss-Prot for DNAJB8 Gene
Efficient suppressor of aggregation and toxicity of disease-associated polyglutamine proteins.