External Ids for DNAJB8 Gene
Previous GeneCards Identifiers for DNAJB8 Gene
The protein encoded by this gene belongs to the DNAJ/HSP40 family of proteins that regulate chaperone activity. This family member suppresses aggregation and toxicity of polyglutamine proteins, and the C-terminal tail is essential for this activity. It has been implicated as a cancer-testis antigen and as a cancer stem-like cell antigen involved in renal cell carcinoma. [provided by RefSeq, Jun 2012]
GeneCards Summary for DNAJB8 Gene
DNAJB8 (DnaJ (Hsp40) Homolog, Subfamily B, Member 8) is a Protein Coding gene. GO annotations related to this gene include unfolded protein binding and protein binding involved in protein folding. An important paralog of this gene is DNAJB7.
UniProtKB/Swiss-Prot for DNAJB8 Gene
Efficient suppressor of aggregation and toxicity of disease-associated polyglutamine proteins.