Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

DNAJB5 Gene

protein-coding   GIFtS: 48
GCID: GC09P034991

DnaJ (Hsp40) homolog, subfamily B, member 5

 Explore 6 diseases affiliated with
DNAJB5 via our new
 Human Malady Compendium 
Biological research products
for DNAJB5
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
DnaJ (Hsp40) Homolog, Subfamily B, Member 51 2     Heat Shock Protein Hsp40-32 3
Hsc401 2 3     DnaJ Homolog Subfamily B Member 52
Heat Shock Protein Cognate 402 3     Heat Shock Cognate 402
Heat Shock Protein Hsp40-22 3     HSC403

External Ids:    HGNC: 148871   Entrez Gene: 258222   Ensembl: ENSG000001370947   OMIM: 6113285   UniProtKB: O759533   

Export aliases for DNAJB5 gene to outside databases

Previous GC identifers: GC09P035301 GC09P035159 GC09P034979 GC09P034990 GC09P034944


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for DNAJB5:
DNAJB5 belongs to the evolutionarily conserved DNAJ/HSP40 protein family. For background information on the DNAJ
family, see MIM 608375.(supplied by OMIM, Mar 2008)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000009.11  NC_018920.1  NT_008413.18  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the DNAJB5 gene promoter:
         HEN1   RelA   ZIC2/Zic2   Tal-1beta   ITF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidDNAJB5 promoter sequence
   Search SABiosciences Chromatin IP Primers for DNAJB5

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DNAJB5


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9p13.3   Ensembl cytogenetic band:  9p13.3   HGNC cytogenetic band: 9p

DNAJB5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DNAJB5 gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09P034991:  view genomic region     (about GC identifiers)

Start:
34,989,638 bp from pter      End:
34,998,897 bp from pter
Size:
9,260 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: DNJB5_HUMAN, O75953 (See protein sequence)
Recommended Name: DnaJ homolog subfamily B member 5  
Size: 348 amino acids; 39133 Da
Sequence caution: Sequence=AAH12115.1; Type=Miscellaneous discrepancy; Note=Unlikely isoform. Aberrant splice sites;
Secondary accessions: B3KN14 B4DSA6 J3KR08 Q5T656 Q8TDR7 Q96EM4
Alternative splicing: 2 isoforms:  O75953-3   O75953-4   

Explore the universe of human proteins at neXtProt for DNAJB5: NX_O75953

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_O75953

  • DNAJB5 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (3 alternative transcripts): 
    NP_001128476.2  NP_001128477.1  NP_036398.3  

    ENSEMBL proteins: 
     ENSP00000404079   ENSP00000444290   ENSP00000393749   ENSP00000439217   ENSP00000433640  
     ENSP00000443151   ENSP00000413684   ENSP00000441999   ENSP00000445536   ENSP00000396332  
     ENSP00000337626   ENSP00000312517  

    Human Recombinant Protein Products: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate (see all 2): DNAJB5
    OriGene Custom Protein Services for DNAJB5 
    GenScript Custom Purified and Recombinant Proteins Services for DNAJB5
    Novus Biologicals DNAJB5 Protein
    Novus Biologicals DNAJB5 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for DNAJB5

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus ----
    GO:0005829cytosol ----


    DNAJB5 for ontologies           About GeneDecksing



    DNAJB5 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for DNAJB5 
    GenScript Custom Superior Antibodies Services for DNAJB5
    Novus Biologicals DNAJB5 Antibodies
    Search for Antibodies for DNAJB5 at Abcam  
    Uscn Antibodies for DNAJB5
    Search ThermoFisher Antibodies for DNAJB5

    Assay Products for DNAJB5: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Immunoassay Development
    Browse OriGene Fluorogenic Cell Assay Kits
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for DNAJB5
    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for DNAJB5


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    DNAJB5 for domains           About GeneDecksing

    4 InterPro domains/families:
     IPR008971 HSP40/DnaJ_pept-bd
     IPR002939 DnaJ_C
     IPR001623 DnaJ_domain
     IPR018253 DnaJ_domain_CS

    Graphical View of Domain Structure for InterPro Entry O75953

    ProtoNet protein and cluster: O75953

    UniProtKB/Swiss-Prot: DNJB5_HUMAN, O75953
    Similarity: Contains 1 J domain


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: DNJB5_HUMAN, O75953
    Induction: Expressed under normal conditions, its expression can further be increased after various stress treatments

    miRNA
    Products:
        
    OriGene 3'-UTR Clone (see all 3): DNAJB5
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat DNAJB5
    8/42 QIAGEN miScript miRNA Assays for microRNAs that regulate DNAJB5 (see all 42):
    hsa-miR-562 hsa-miR-429 hsa-miR-3138 hsa-miR-766 hsa-miR-649 hsa-miR-3613-3p hsa-miR-1243 hsa-miR-520g
    SwitchGear 3'UTR luciferase reporter plasmidDNAJB5 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DNAJB5 (see all 7)
    OriGene shRNA RFP: DNAJB5
    OriGene siRNA: DNAJB5
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DNAJB5

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for DNAJB5

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DNAJB5 (see all 5)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DNAJB5 (see all 3)
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector (see all 3): DNAJB5 (NM_001135004)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for DNAJB5
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DNAJB5 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for DNAJB5
    Search LifeMap BioReagents cell lines for DNAJB5

    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DNAJB5

    Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
    GO:0031072heat shock protein binding IEA--
    GO:0051082unfolded protein binding IEA--


    DNAJB5 for ontologies           About GeneDecksing



    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for DNAJB5

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    5/8 Interacting proteins for DNAJB5 (O759531, 2, 3 ENSP000004136844) via UniProtKB, MINT, STRING, and/or I2D (see all 8)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CACNA1AO005551, 3EBI-5655937,EBI-766279 I2D: score=1 
    HDAC4P565243, ENSP000002646064I2D: score=1 STRING: ENSP00000264606
    TBPL2Q6SJ963, ENSP000002472194I2D: score=1 STRING: ENSP00000247219
    WIPI2Q9Y4P83I2D: score=1 
    TTNQ8WZ421EBI-5655937,EBI-3448943
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000122negative regulation of transcription from RNA polymerase II promoter ----
    GO:0006457protein folding IEA--
    GO:0006986response to unfolded protein IEP10570961


    DNAJB5 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for DNAJB5
    Search CenterWatch for drugs/clinical trials and news about DNAJB5 / DNJB5 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for DNAJB5 gene (3 alternative transcripts): 
    NM_001135004.2  NM_001135005.2  NM_012266.5  

    Unigene Cluster for DNAJB5:

    DnaJ (Hsp40) homolog, subfamily B, member 5
    Hs.237506  [show with all ESTs]
    Unigene Representative Sequence: NM_001135005
    12 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000453597(uc003zvs.3 uc003zvt.3) ENST00000538278 ENST00000458263
    ENST00000537321 ENST00000469798 ENST00000541010 ENST00000454002(uc011los.2)
    ENST00000545841 ENST00000539059 ENST00000443266 ENST00000335998 ENST00000312316


    miRNA
    Products:
         
    OriGene 3'-UTR Clone (see all 3): DNAJB5
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat DNAJB5
    8/42 QIAGEN miScript miRNA Assays for microRNAs that regulate DNAJB5 (see all 42):
    hsa-miR-562 hsa-miR-429 hsa-miR-3138 hsa-miR-766 hsa-miR-649 hsa-miR-3613-3p hsa-miR-1243 hsa-miR-520g
    SwitchGear 3'UTR luciferase reporter plasmidDNAJB5 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DNAJB5 (see all 7)
    OriGene shRNA RFP: DNAJB5
    OriGene siRNA: DNAJB5
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DNAJB5
    Clone
    Products:
         
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DNAJB5 (see all 5)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DNAJB5 (see all 3)
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector (see all 3): DNAJB5 (NM_001135004)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for DNAJB5
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DNAJB5 
    Primer
    Products:
        
    OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DNAJB5
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat DNAJB5
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DNAJB5
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DNAJB5

    Additional cDNA sequence: 

    AF087870.1 AF088982.1 AK023253.1 AK299647.1 AK314671.1 

    10 DOTS entries:

    DT.100780870  DT.97843206  DT.99959264  DT.121195482  DT.121195434  DT.121195477  DT.95214211  DT.95272464 
    DT.95272468  DT.95301276 

    24/174 AceView cDNA sequences (see all 174):

    AA243753 F10358 AI971233 AI858541 BM916097 BM708810 BU507074 F06929 
    AK023253 BQ003935 BM693637 F30111 BC012115 BI915181 AW006148 BF793558 
    AW135625 BU845478 AF088982 F03633 AI282139 AW498583 BM424096 AI023186 

    GeneLoc Exon Structure

    5/9 Alternative Splicing Database (ASD) splice patterns (SP) for DNAJB5 (see all 9)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b · 2c ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7a · 7b ^ 8a · 8b · 8c · 8d ^ 9
    SP1:                    -     -     -           -     -                                                         
    SP2:                    -     -     -           -     -                                                         
    SP3:                    -     -           -     -     -                                                         
    SP4:                    -     -     -     -     -     -                                                         
    SP5:                    -                 -     -     -                                                         


    ECgene alternative splicing isoforms for DNAJB5

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    DNAJB5 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CACAAGAAGC

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image

    DNAJB5 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    10 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    Neural TubeNeural TubeSpinal Neural Tube CellsNeural Ectoderm
    BrainCerebral CortexBrain
    BrainHypothalamusBrain
    BrainThalamusBrain
    EyeRetinaEye
    HeartOutflow TractHeart
    Neural TubeDiencephalonNeural Tube
    Neural TubeMetencephalonNeural Tube
    Neural TubeTelencephalonNeural Tube
    Spinal CordPresumptive Spinal CordSpinal Cord
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See DNAJB5 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for DNAJB5

    SOURCE GeneReport for Unigene cluster: Hs.237506
        SABiosciences Expression via Pathway-Focused PCR Arrays including DNAJB5: 
              Cellular Stress Responses in human mouse rat
              Heat Shock Proteins & Chaperones in human mouse rat

    Primer
    Products:
    OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DNAJB5
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat DNAJB5
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DNAJB5
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DNAJB5
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DNAJB5

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for DNAJB5 gene from 8/30 species (see all 30)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves DNAJB51 DnaJ (Hsp40) homolog, subfamily B, member 5 78.74(n)
    86.91(a)
      427409  XM_424983.3  XP_424983.2 
    lizard
    (Anolis carolinensis)
    Reptilia DNAJB56
    --
    85(a)
    1 ↔ 1
    GL343305.1(1596238-1610818)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.181932 Transcribed sequence with moderate similarity to protein more 79.22(n)    AL956919.2 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC5694661 novel protein similar to vertebrate DnaJ (Hsp40) homolog, more 72.53(n)
    78.1(a)
      569466  NM_001100040.1  NP_001093510.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta DnaJ-13
    CG50011
    chaperone3
    CG50011
    50(a)
    (best of 3)3
    59.39(n)1
    56.05(a)1
      64E53
    333081  NM_134742.31  NP_608586.21 
    worm
    (Caenorhabditis elegans)
    Secernentea dnj-136
    DNaJ domain (prokaryotic heat shock protein) famil...
    55(a)
    1 → many
    II(11545637-11547302)
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT5G255301 putative DNAJ heat shock protein 51.37(n)
    47.72(a)
      832628  NM_122464.1  NP_197935.1 
    rice
    (Oryza sativa)
    Liliopsida Os.354632 Oryza sativa (japonica cultivar-group) cDNA cloneJ more 75.2(n)    AK067414.1 


    ENSEMBL Gene Tree for DNAJB5 (if available)
    TreeFam Gene Tree for DNAJB5 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for DNAJB5 gene
    DNAJB42  DNAJC32  DNAJB132  DNAJB22  DNAJB92  DNAJC112  DNAJB62  DNAJC72  
    DNAJB12  DNAJB72  DNAJB82  
    18/27 SIMAP similar genes for DNAJB5 using alignment to 9 protein entries:     DNJB5_HUMAN (see all proteins) (see all similar genes):
    DNAJA3    DNAJC16    DNAJC5B    DNAJB4    DNAJC1    DNAJB1
    DNAJB2    DNAJC18    DNAJC5G    LOC51277    DNAJB6    DNAJB3
    DNAJC10    DNAJB13    DNAJC17    MST104    DNAJA4    DNAJB12

    DNAJB5 for paralogs           About GeneDecksing


    3 Pseudogenes.org Pseudogenes for DNAJB5
    PGOHUM00000263088 PGOHUM00000235987 PGOHUM00000236217


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/157 NCBI SNPs in DNAJB5 are shown (see all 157    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 9 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1422485851,2
    --34987704(+) AGATCG/TGAGGA 2 -- us2k10--------
    rs1884255781,2
    --34987719(+) GCAGCA/GGTGCA 2 -- us2k10--------
    rs1932076011,2
    --34987731(+) GGCCCC/TTCACC 2 -- us2k10--------
    rs1855461891,2
    --34987827(+) TGTGCC/TTCATC 2 -- us2k10--------
    rs1141972611,2
    --34987872(+) ACCCTG/ACCTTC 2 -- us2k11Minor allele frequency- A:0.01WA 118
    rs70486131,2
    C,F,--34987944(+) GAGGAA/C/G/
            
    AGGAG
    2 -- us2k1 trp32WA EA 238
    rs70354591,2
    C,--34988026(+) tcaccG/Atcctc 2 -- us2k11Minor allele frequency- A:0.00CSA 1
    rs106472251,2
    C,--34988088(+) TCATGCTC/-CTCAT 2 -- us2k11Minor allele frequency- -:0.50CSA 2
    rs1994985081,2
    C--34988092(+) TGCTCA/CTTTCC 2 -- us2k10--------
    rs1503866141,2
    C,--34988285(+) TGGCA-/CCCCCC 3 -- us2k10--------

    HapMap Linkage Disequilibrium report for DNAJB5 (34989638 - 34998897 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for DNAJB5: --

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DNAJB5
    DNA2.0 Custom Variant and Variant Library Synthesis for DNAJB5

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    DNAJB5 for disorders           About GeneDecksing

    OMIM gene information: 611328    OMIM disorders: --

    6 diseases for DNAJB5:    About MalaCards
    macular degeneration    ataxia    pneumonia    tuberculosis
    malaria    mycobacterium tuberculosis


    Export disorders for DNAJB5 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for DNAJB5 gene, integrated from 9 sources (see all 12):
    (articles sorted by number of sources associating them with DNAJB5)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Hsc40, a new member of the hsp40 family, exhibits similar expression profile to that of hsc70 in mammalian cells. (PubMed id 10570961)1, 2, 3 Chen M.-S.... Laszlo A. (1999)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    3. Mammalian HSP40/DNAJ homologs: cloning of novel cDNAs and a proposal for their classification and nomenclature. (PubMed id 11147971)1, 3 Ohtsuka K. and Hata M. (2000)
    4. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    5. Comparison of an expanded ataxia interactome with pat ient medical records reveals a relationship between macular degeneration and at axia. (PubMed id 21078624)1 Kahle J.J....Zoghbi H.Y. (2011)
    6. A redox-dependent pathway for regulating class II HDACs and cardiac hypertrophy. (PubMed id 18555775)1 Ago T....Sadoshima J. (2008)
    7. Identification of intracellular proteins associated w ith the EBV-encoded nuclear antigen 5 using an efficient TAP procedure and FT-I CR mass spectrometry. (PubMed id 18457437)1 Forsman A....Rymo L. (2008)
    8. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    9. Notch-induced E2A degradation requires CHIP and Hsc70 as novel facilitators of ubiquitination. (PubMed id 15456869)1 Huang Z....Sun X.H. (2004)
    10. DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)2 Humphray S.J.... Dunham I. (2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 25822 HGNC: 14887 AceView: DNAJB5 Ensembl:ENSG00000137094 euGenes: HUgn25822
    ECgene: DNAJB5 H-InvDB: DNAJB5

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for DNAJB5 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for DNAJB5 gene:
    Search GeneIP for patents involving DNAJB5

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
    In Situ Hybridization Assays from
    Advanced Cell Diagnostics
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Phosphatase Activity Assays/Reagents   Browse Recombinant/Natural Proteins  
     Browse OriGene Antibodies   OriGene shRNA RFP for DNAJB5  
     OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DNAJB5   OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DNAJB5  
     OriGene Protein Over-expression Lysate for DNAJB5   Browse OriGene Fluorogenic Cell Assay Kits  
     OriGene siRNA for DNAJB5   OriGene 3'-UTR Clone for DNAJB5  
     OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DNAJB5   OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DNAJB5  
     Browse OriGene GFP tagged cDNA clones in CMV expression vector   Browse OriGene MicroRNA Expression Plasmids  
     Browse OriGene basic RS shRNAs   Browse OriGene validated miRNA SYBR primer pairs  
     Browse OriGene full length recombinant human proteins expressed in human HEK293 cells   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for DNAJB5   OriGene Custom Protein Services for DNAJB5  
     OriGene Custom Immunoassay Development  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat DNAJB5
     QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DNAJB5
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DNAJB5
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DNAJB5
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DNAJB5
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DNAJB5
     GenScript Custom Purified and Recombinant Proteins Services for DNAJB5 GenScript cDNA clones with any tag delivered in your preferred vector for DNAJB5
     GenScript Custom Assay Services for DNAJB5 GenScript Custom Superior Antibodies Services for DNAJB5
     GenScript Custom overexpressing Cell Line Services for DNAJB5 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in DNAJB5 promoter
     Search Chromatin IP Primers for DNAJB5
     RT2 qPCR Primer Assay in human, mouse, rat DNAJB5
     Search GNC Networks for DNAJB5
     SABiosciences PCR Arrays including human, mouse, rat DNAJB5
     Search Tocris compounds for DNAJB5
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological cDNA Clones
     Antibodies/Proteins Production Services
     Rabbit Monoclonal Antibody Platform
     Bulk Purchasing
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     DNAJB5 antibodies
     DNAJB5 proteins
     DNAJB5 lysates
     Search for Antibodies for DNAJB5 at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for DNAJB5
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     DNAJB5 Proteins, Antibodies, CLIAs, and ELISAs
     Search LifeMap BioReagents cell lines for DNAJB5
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DNAJB5
     SwitchGear 3'UTR luciferase reporter plasmids for DNAJB5
     SwitchGear Promoter luciferase reporter plasmids for DNAJB5
     Search ThermoFisher Antibodies for DNAJB5
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DNAJB5
           
    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

    View Random Gene

    Category
    VWF
    (GIFTS: 73)
    von Willebrand factor
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      DNAJB5 gene at Home site.
    hostname: 356980-web2.xennexinc.com index build: 100 solr: 1.4