Aliases for DNAJB4 Gene
Aliases for DNAJB4 Gene
External Ids for DNAJB4 Gene
- HGNC: 14886
- Entrez Gene: 11080
- Ensembl: ENSG00000162616
- OMIM: 611327
- UniProtKB: Q9UDY4
Previous GeneCards Identifiers for DNAJB4 Gene
- GC01P078623
- GC01P077417
- GC01P077835
- GC01P077893
- GC01P078182
- GC01P078444
- GC01P076602
Summaries for DNAJB4 Gene
-
The protein encoded by this gene is a molecular chaperone, tumor suppressor, and member of the heat shock protein-40 family. The encoded protein binds the cell adhesion protein E-cadherin and targets it to the plasma membrane. This protein also binds incorrectly folded E-cadherin and targets it for endoplasmic reticulum-associated degradation. This gene is a strong tumor suppressor for colorectal carcinoma, and downregulation of it may serve as a good biomarker for predicting patient outcomes. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]
GeneCards Summary for DNAJB4 Gene
DNAJB4 (DnaJ Heat Shock Protein Family (Hsp40) Member B4) is a Protein Coding gene. GO annotations related to this gene include unfolded protein binding and chaperone binding. An important paralog of this gene is DNAJB1.
UniProtKB/Swiss-Prot for DNAJB4 Gene
-
Probable chaperone. Stimulates ATP hydrolysis and the folding of unfolded proteins mediated by HSPA1A/B (in vitro) (PubMed:24318877).
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for DNAJB4 Gene
Genomics for DNAJB4 Gene
Regulatory Elements for DNAJB4 Gene
Enhancers for DNAJB4 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH01G078002 | 2 | FANTOM5 Ensembl ENCODE dbSUPER | 11.9 | +27.8 | 27754 | 8.6 | HNRNPUL1 HDGF PKNOX1 FOXA2 CREB3L1 ARNT AGO1 WRNIP1 ZFP64 ARID4B | DNAJB4 RPL17P6 LOC653631 GIPC2 NEXN ENSG00000273338 LOC100131495 |
| GH01G077680 | 1.1 | ENCODE | 6.5 | -296.3 | -296278 | 4.0 | HDGF PKNOX1 MLX ARNT CREB3L1 ZFP64 WRNIP1 ARID4B SIN3A DMAP1 | RPL17P6 GIPC2 AK5 DNAJB4 ZZZ3 RN7SL370P |
| GH01G077975 | 1.4 | ENCODE dbSUPER | 0.7 | -0.9 | -894 | 5.5 | HDGF PKNOX1 FOXA2 ARNT CREB3L1 WRNIP1 SIN3A FEZF1 DMAP1 ZNF2 | RPL17P6 GIPC2 NEXN DNAJB4 NEXN-AS1 |
| GH01G077949 | 0.8 | ENCODE dbSUPER | 0.3 | -29.9 | -29925 | 0.2 | PAF1 CTCF SMC3 EBF1 RAD21 | DNAJB4 NEXN-AS1 |
| GH01G077959 | 0.5 | dbSUPER | 0.4 | -18.0 | -17996 | 3.3 | ZNF664 PAF1 POLR2A | USP33 NEXN DNAJB4 NEXN-AS1 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around DNAJB4 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the DNAJB4 gene promoter:
Regulatory Element Products
Genomic Location for DNAJB4 Gene
- Chromosome:
- 1
- Start:
- 77,979,175 bp from pter
- End:
- 78,018,721 bp from pter
- Size:
- 39,547 bases
- Orientation:
- Plus strand
Genomic View for DNAJB4 Gene
Genes around DNAJB4 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 1p31.1 by Ensembl
- 1p31.1 by Entrez Gene
- 1p31.1 by HGNC
DNAJB4 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for DNAJB4 Gene
Proteins for DNAJB4 Gene
-
Protein details for DNAJB4 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9UDY4-DNJB4_HUMAN
- Recommended name:
- DnaJ homolog subfamily B member 4
- Protein Accession:
- Q9UDY4
- B2R824
- Q13431
Protein attributes for DNAJB4 Gene
- Size:
- 337 amino acids
- Molecular mass:
- 37807 Da
- Quaternary structure:
-
- Homodimer. The C-terminal section interacts with the C-terminal tail of OPRM1. Interacts also with SDIM1.
Protein Expression for DNAJB4 Gene
Post-translational modifications for DNAJB4 Gene
Other Protein References for DNAJB4 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for DNAJB4
- Invitrogen Antibodies for DNAJB4
- antibodies-online Antibodies for DNAJB4: See all 43
- GeneTex DNAJB4 antibody for DNAJB4
-
Santa Cruz Biotechnology (SCBT) Antibodies for DNAJB4
Protein Products
-
OriGene Purified Proteins for DNAJB4
- Search Origene for MassSpec and Protein Over-expression Lysates for DNAJB4
- Origene Custom Protein Services for DNAJB4
- ProSpec Recombinant Proteins for DNAJB4
- antibodies-online Proteins for DNAJB4: See all 9
- Search antibodies-online for peptides
- Search GeneTex for Proteins for DNAJB4
No data available for DME Specific Peptides for DNAJB4 Gene
Domains & Families for DNAJB4 Gene
Gene Families for DNAJB4 Gene
Protein Domains for DNAJB4 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for DNAJB4 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
No data available for UniProtKB/Swiss-Prot for DNAJB4 Gene
Function for DNAJB4 Gene
Molecular function for DNAJB4 Gene
- UniProtKB/Swiss-Prot Function:
- Probable chaperone. Stimulates ATP hydrolysis and the folding of unfolded proteins mediated by HSPA1A/B (in vitro) (PubMed:24318877).
- UniProtKB/Swiss-Prot Induction:
- By heat shock.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001671 | ATPase activator activity | IDA | 24318877 |
| GO:0005515 | protein binding | IPI | 21255413 |
| GO:0051082 | unfolded protein binding | TAS,IEA | -- |
| GO:0051087 | chaperone binding | IPI | 21231916 |
Phenotypes for DNAJB4 Gene
- GenomeRNAi human phenotypes for DNAJB4:
-
- Increased viability
- Increased vaccinia virus (VACV) infection
- Increased gamma-H2AX phosphorylation
- shRNA abundance <= 50%
- Lamellipodia cells
- Dynamic nuclei (hole, folded or small irregular)
- Increased shRNA abundance (Z-score > 2)
- Decreased shRNA abundance (Z-score < -2)
- Decreased homologous recombination repair frequency
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for DNAJB4
-
-
ViGene Biosciences lentiviral particle packaged cDNA for DNAJB4 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for DNAJB4 gene
- Search ViGene Biosciences for DNAJB4
CRISPR Products
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-
Santa Cruz Biotechnology (SCBT) CRISPR for DNAJB4
- GenScript: Design CRISPR guide RNA sequences for DNAJB4
miRNA for DNAJB4 Gene
- miRTarBase miRNAs that target DNAJB4
-
- hsa-mir-16-5p (MIRT001471)
- hsa-mir-148b-3p (MIRT019300)
- hsa-mir-142-3p (MIRT021629)
- hsa-mir-215-5p (MIRT024618)
- hsa-mir-148a-3p (MIRT026002)
- hsa-mir-192-5p (MIRT026165)
- hsa-mir-103a-3p (MIRT027036)
- hsa-mir-30a-5p (MIRT028464)
- hsa-mir-26b-5p (MIRT028881)
- hsa-mir-548n (MIRT079618)
- hsa-mir-1284 (MIRT079621)
- hsa-mir-3607-5p (MIRT079623)
- hsa-mir-4666a-5p (MIRT079631)
- hsa-mir-1206 (MIRT198429)
- hsa-mir-5089-5p (MIRT290012)
- hsa-mir-183-3p (MIRT478064)
- hsa-mir-5696 (MIRT478065)
- hsa-mir-877-5p (MIRT478066)
- hsa-mir-4524a-3p (MIRT478067)
- hsa-mir-15b-3p (MIRT478068)
- hsa-mir-4729 (MIRT478069)
- hsa-mir-3976 (MIRT478070)
- hsa-mir-6859-5p (MIRT478071)
- hsa-mir-3916 (MIRT478072)
- hsa-mir-3125 (MIRT478073)
- hsa-mir-4641 (MIRT478074)
- hsa-mir-7853-5p (MIRT478075)
- hsa-mir-105-5p (MIRT478076)
- hsa-mir-577 (MIRT478077)
- hsa-mir-7-2-3p (MIRT478078)
- hsa-mir-7-1-3p (MIRT478079)
- hsa-mir-365a-3p (MIRT478080)
- hsa-mir-365b-3p (MIRT478081)
- hsa-mir-3674 (MIRT538047)
- hsa-mir-135b-3p (MIRT538048)
- hsa-mir-7156-3p (MIRT538049)
- hsa-mir-6516-3p (MIRT538050)
- hsa-mir-1255b-5p (MIRT538051)
- hsa-mir-1255a (MIRT538052)
- hsa-mir-3121-5p (MIRT538053)
- hsa-mir-7845-5p (MIRT538054)
- hsa-mir-4802-3p (MIRT538055)
- hsa-mir-586 (MIRT558348)
- hsa-mir-7151-3p (MIRT688453)
- hsa-mir-5095 (MIRT688454)
- hsa-mir-5589-5p (MIRT688455)
- hsa-mir-4731-5p (MIRT688456)
- hsa-mir-6778-3p (MIRT688457)
- hsa-mir-6506-5p (MIRT688458)
- hsa-mir-619-5p (MIRT688459)
- hsa-mir-7107-5p (MIRT688460)
- hsa-mir-1234-3p (MIRT688461)
- hsa-mir-186-3p (MIRT688462)
- hsa-mir-1273g-3p (MIRT688463)
- hsa-mir-520h (MIRT688464)
- hsa-mir-520g-3p (MIRT688465)
- hsa-mir-6504-3p (MIRT688466)
- hsa-mir-512-3p (MIRT688467)
- hsa-mir-4438 (MIRT688468)
- hsa-mir-93-5p (MIRT688469)
- hsa-mir-526b-3p (MIRT688470)
- hsa-mir-519d-3p (MIRT688471)
- hsa-mir-20b-5p (MIRT688472)
- hsa-mir-20a-5p (MIRT688473)
- hsa-mir-17-5p (MIRT688474)
- hsa-mir-106b-5p (MIRT688475)
- hsa-mir-106a-5p (MIRT688476)
- hsa-mir-520a-3p (MIRT688477)
- hsa-mir-372-3p (MIRT688478)
- hsa-mir-302e (MIRT688479)
- hsa-mir-302c-3p (MIRT688480)
- hsa-mir-373-3p (MIRT688481)
- hsa-mir-302b-3p (MIRT688482)
- hsa-mir-302a-3p (MIRT688483)
- hsa-mir-520b (MIRT688484)
- hsa-mir-520c-3p (MIRT688485)
- hsa-mir-520d-3p (MIRT688486)
- hsa-mir-520e (MIRT688487)
- hsa-mir-302d-3p (MIRT688488)
- hsa-mir-6878-3p (MIRT704175)
- hsa-mir-6744-3p (MIRT704176)
- hsa-mir-4757-5p (MIRT704177)
- hsa-mir-4312 (MIRT704178)
- hsa-mir-150-5p (MIRT704179)
- hsa-mir-212-5p (MIRT704180)
- hsa-mir-6747-3p (MIRT704181)
- hsa-mir-3973 (MIRT704182)
miRNA Products
- Search ViGene Biosciences for DNAJB4
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for DNAJB4
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ViGene Biosciences ready-to-package AAV shRNAs for DNAJB4 gene
Clone Products
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- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for DNAJB4
- VectorBuilder custom plasmid, inducible vectors for DNAJB4
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for DNAJB4
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for DNAJB4
-
ViGene Biosciences adenoviral particle packaged cDNA for DNAJB4 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for DNAJB4 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for DNAJB4 gene
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for DNAJB4 Gene
Localization for DNAJB4 Gene
Subcellular locations from UniProtKB/Swiss-Prot for DNAJB4 Gene
- Cytoplasm. Cell membrane. Note=Cytoplasmic according to PubMed:18837411 and membrane-associated according to PubMed:16542645.
| Compartment | Confidence |
|---|---|
| extracellular | 5 |
| cytosol | 5 |
| plasma membrane | 4 |
| nucleus | 3 |
| mitochondrion | 1 |
| endoplasmic reticulum | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0005829 | cytosol | IDA | 21231916 |
| GO:0005886 | plasma membrane | IEA | -- |
| GO:0016020 | membrane | IEA | -- |
| GO:0070062 | extracellular exosome | IDA | 23376485 |
Pathways & Interactions for DNAJB4 Gene
No Data Available
Interacting Proteins for DNAJB4 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006457 | protein folding | IEA | -- |
| GO:0006986 | response to unfolded protein | TAS | 9546042 |
| GO:0009408 | response to heat | TAS | 9546042 |
| GO:0032781 | positive regulation of ATPase activity | IEA | -- |
No data available for Pathways by source and SIGNOR curated interactions for DNAJB4 Gene
Transcripts for DNAJB4 Gene
mRNA/cDNA for DNAJB4 Gene
- (6) REFSEQ mRNAs :
- (5) Additional mRNA sequences :
- (201) Selected AceView cDNA sequences:
- (6) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for DNAJB4 Gene
CRISPR Products
-
OriGene CRISPR knockouts for DNAJB4
-
Santa Cruz Biotechnology (SCBT) CRISPR for DNAJB4
- GenScript: Design CRISPR guide RNA sequences for DNAJB4
miRNA Products
- Search ViGene Biosciences for DNAJB4
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for DNAJB4
- Browse OriGene Inhibitory RNA Products For DNAJB4
-
ViGene Biosciences ready-to-package AAV shRNAs for DNAJB4 gene
Clone Products
-
OriGene ORF clones in human for DNAJB4
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for DNAJB4
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for DNAJB4
- VectorBuilder custom plasmid, inducible vectors for DNAJB4
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for DNAJB4
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
| ExUns: | 1 | ^ | 2 | ^ | 3a | · | 3b |
|---|---|---|---|---|---|---|---|
| SP1: | |||||||
| SP2: | - |
Expression for DNAJB4 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Brain (Nervous System)
-
Testis (Reproductive System)
- Leydig Cells Testis Interstitium
-
Liver (Hepatobiliary System)
- Hepatocytes Liver Lobule
- Intestine (Gastrointestinal Tract)
-
Thyroid (Endocrine System)
-
Adrenal Gland (Endocrine System)
This gene is overexpressed in Rectum (7.3), Urinary Bladder (6.7), and Prostate (6.3).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for DNAJB4 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of DNAJB4 Gene:
DNAJB4SOURCE GeneReport for Unigene cluster for DNAJB4 Gene:
Hs.13852mRNA Expression by UniProt/SwissProt for DNAJB4 Gene:
Q9UDY4-DNJB4_HUMAN
Tissue specificity:
Expressed in heart, pancreas and skeletal muscle, and to a lesser extent in brain, placenta and liver.
Evidence on tissue expression from TISSUES for DNAJB4 Gene
- Liver(4.4)
- Nervous system(3.9)
- Heart(2.2)
- Lung(2.1)
- Spleen(2)
Primer Products
-
OriGene qPCR primer pairs for DNAJB4
-
OriGene qPCR primer pairs and template standards for DNAJB4
No data available for mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for DNAJB4 Gene
Orthologs for DNAJB4 Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | DNAJB4 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | DNAJB4 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | DNAJB4 34 35 |
|
||
| mouse (Mus musculus) |
Mammalia | Dnajb4 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Dnajb4 34 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | DNAJB4 35 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | DNAJB4 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | DNAJB4 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | DNAJB4 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | dnajb4 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | dnajb4 34 35 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | DnaJ-1 36 34 35 |
|
||
| CG5001 36 35 |
|
||||
| CG2887 36 35 |
|
||||
| CG12020 36 |
|
|
|||
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP007107 34 |
|
||
| worm (Caenorhabditis elegans) |
Secernentea | dnj-13 34 35 |
|
||
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | SIS1 37 |
|
|
|
| thale cress (Arabidopsis thaliana) |
eudicotyledons | AT5G25530 34 |
|
||
| Alicante grape (Vitis vinifera) |
eudicotyledons | Vvi.7032 34 |
|
||
| rice (Oryza sativa) |
Liliopsida | Os02g0128400 34 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 35 |
|
OneToMany |
- Species where no ortholog for DNAJB4 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for DNAJB4 Gene
Paralogs for DNAJB4 Gene
(23) SIMAP similar genes for DNAJB4 Gene using alignment to 4 proteins:
Variants for DNAJB4 Gene
| SNP ID | Clin | Chr 01 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs587778373 | untested | 77,978,949(-) | CGGTG(A/G)TGGCG | nc-transcript-variant, upstream-variant-2KB, reference, missense | |
| rs1000017085 | -- | 78,002,646(+) | AAGCT(A/G)TAAGT | intron-variant | |
| rs1000066176 | -- | 78,011,725(+) | GTGAT(A/C)CACCC | intron-variant | |
| rs1000078153 | -- | 78,000,965(+) | ACCAG(A/C)CTGGG | intron-variant | |
| rs1000193945 | -- | 77,991,295(+) | TCTCA(A/G)TAATG | intron-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv3586533 | CNV | loss | 21293372 |
Residual Variation Intolerance Score:
29.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.43;
9.37% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for DNAJB4 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- DNAJB4
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for DNAJB4 Gene
Disorders for DNAJB4 Gene
Relevant External Links for DNAJB4
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- DNAJB4
No disorders were found for DNAJB4 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for DNAJB4 Gene
Publications for DNAJB4 Gene
- Isolation of a new member of DnaJ-like heat shock protein 40 (Hsp40) from human liver. (PMID: 9546042) Hoe K.L. … Yoo H.S. (Biochim. Biophys. Acta 1998) 2 3 4 22 64
- Binding of human nucleotide exchange factors to heat shock protein 70 (Hsp70) generates functionally distinct complexes in vitro. (PMID: 24318877) Rauch J.N. … Gestwicki J.E. (J. Biol. Chem. 2014) 3 4 64
- A novel neuron-enriched protein SDIM1 is down regulated in Alzheimer's brains and attenuates cell death induced by DNAJB4 over- expression in neuro-progenitor cells. (PMID: 21255413) Lei J.X. … Liu Q.Y. (Mol. Neurodegener. 2011) 3 4 64
- Preparation of the anti-HLJ1 monoclonal antibodies and establishment of method for detection of the antigen. (PMID: 18837411) Lin X. … Wang X. (Sheng Wu Gong Cheng Xue Bao 2008) 4 22 64
- A member of the heat shock protein 40 family, hlj1, binds to the carboxyl tail of the human mu opioid receptor. (PMID: 16542645) Ancevska-Taneva N. … Simon E.J. (Brain Res. 2006) 3 4 64
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- Design optimal peptide antigens
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- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for DNAJB4
- Sino Biological Human cDNA Clone for DNAJB4
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Proteins
- Sino Biological Antibodies
- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for DNAJB4
- Novus Biologicals proteins and lysates for DNAJB4
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- ProSpec Recombinant Proteins for DNAJB4
- Invitrogen Antibodies for DNAJB4
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for DNAJB4
- antibodies-online Antibodies for DNAJB4: See all 43
- Search antibodies-online for kits
- antibodies-online Proteins for DNAJB4: See all 9
- Search antibodies-online for peptides
- GeneTex DNAJB4 antibody for DNAJB4
- Search GeneTex for Proteins for DNAJB4
- ViGene Biosciences adenoviral particle packaged cDNA for DNAJB4 gene
- ViGene Biosciences lentiviral particle packaged cDNA for DNAJB4 gene
- ViGene Biosciences ready-to-package AAV shRNAs for DNAJB4 gene
- Search ViGene Biosciences for DNAJB4
- Santa Cruz Biotechnology (SCBT) Antibodies for DNAJB4
- Search Santa Cruz Biotechnology (SCBT) for DNAJB4 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for DNAJB4
- Horizon Cell Lines for DNAJB4
- Cyagen custom Knockout/knockin (KOKI) mouse models for DNAJB4
- VectorBuilder custom plasmid, inducible vectors for DNAJB4
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for DNAJB4
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for DNAJB4 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer